Materialeffizienz und Produktdauerverlängerung in der Messewirtschaft: Handlungsbedarf, Strategien, Lösungen

Das Wuppertal Paper von Rainer Lucas und Sandra Kolberg stellt sich der Frage, wie im Bereich der Messewirtschaft und insbesondere im Messebau die Materialeffizienz erhöht werden kann. Angesichts der kurzen Nutzungsdauer vieler Messestände und ihrer Ausstattungen konzentriert sich das Paper auf das Thema Produktdauerverlängerung. Die hiermit verbundenen Strategien werden zunächst auf ihre mögliche Anwendbarkeit in der Messewirtschaft überprüft. Danach wird es praktisch. Innovative Vorschläge und Konzepte für den Messestandbau, die Standausstattungen und neue Beratungs- und Informationsangebote werden vorgestellt. Hierbei wird deutlich: Bereits bei der Planung des Messestandes sollte auf die Recyclingfähigkeit der verwendeten Materialien geachtet werden. Das Produkt-Design bestimmt im Wesentlichen die Möglichkeiten einer Mehrfachnutzung und einer sinnvollen Nach- und Weiternutzung. Die Arbeit zeigt abschließend unter Beachtung der ökonomischen Rahmenbedingungen auf, welche Innovationspotenziale noch erschlossen werden können. Die vielen aufgeführten Beispiele belegen aber auch: in der Branche wird zunehmend erkannt, dass Materialeffizienz und Produktdauerverlängerung aufgrund der hohen Rohstoffpreise zu einem Wettbewerbsfaktor werden. -- The Wuppertal Paper written by Rainer Lucas and Sandra Kolberg confronts the questions how the concept of material efficiency in the exhibition industry and especially in the business of trade fair construction could be increased. Considering a rather short service life of most exhibition stands and their equipment and accessories, the paper focuses the subject of extension of service life. Strategies usually applied to this approach are first examined regarding their applicability in the exhibition industry. Thereafter some practical consideration are following. Innovative proposals and concepts for trade fair construction, stand equipment and new information and consultancy tools are presented. It turns out to be crucial, that already during the stand's planning phase, the ability of material recycling should be taken into account. The product design determines fundamentally the possibilities for reuse or of a reasonable further usage. Finally, the paper shows - by considering the economical general framework of the exhibition industry - where potentials for innovations can be explored. Besides, the examples shown in here make clear that material efficiency and extension of service life are meeting growing economical importance because they become a relevant factor for competitiveness on the market.

Resource intensity in global food chains : the hot spot analysis

Purpose - The Hot Spot Analysis developed by the Wuppertal Institute is a screening tool focussing on the demand of reliable sustainability-oriented decision-making processes in complex value chains identifying high priority areas ("hot spots") for effective measures in companies. This paper aims to focus on this tool. Design/methodology/approach - The Hot Spot Analysis is a qualitative method following a cradle-to-cradle approach. With the examples of coffee and cream cheese hot spots of sustainability indicators throughout the entire life cycle are identified and evaluated with data from literature reviews and expert consultations or stakeholder statements. This paper focuses on the indicator resource efficiency as an example of how the methodology works. Findings - The identified hot spots for coffee are the raw material procurement phase in terms of abiotic material, water and energy consumption, the production phase concerning biotic material and the energy consumption in the use phase. For cream cheese relevant hot spots appear in the raw material procurement phase in terms of biotic materials and water as well as biotic materials and energy consumption during the production phase. Research limitations/implications - Life cycle analyses connected to indicators like resource efficiency need to be applied as consequent steps of a Hot Spot Analysis if a deeper level of analysis is eventually aimed at which is more cost and time intensive in the short term. The Hot Spot Analysis can be combined with other sustainability management instruments. Practical implications - Research and management can be directed to hot spots of sustainability potential quickly which pays off in the long term. Originality/value - The paper shows that companies can address sustainability potentials relatively cost moderately

Alles im grünen Bereich!

ALLES IM GRÜNEN BEREICH! Alles im grünen Bereich! / Miller, Leif (Rights reserved) ( -

Long-term follow-up of cats in complete remission after treatment of feline infectious peritonitis with oral GS-441524

Objectives Feline infectious peritonitis (FIP), a common disease in cats caused by feline coronavirus (FCoV), is usually fatal once clinical signs appear. Successful treatment of FIP with oral GS-441524 for 84 days was demonstrated recently by this research group. The aim of this study was to evaluate the long-term outcome in these cats. Methods A total of 18 successfully treated cats were followed for up to 1 year after treatment initiation (9 months after completion of the antiviral treatment). Follow-up examinations were performed at 12-week intervals, including physical examination, haematology, serum biochemistry, abdominal and thoracic ultrasound, FCoV ribonucleic acid (RNA) loads in blood and faeces by reverse transciptase-quantitative PCR and anti-FCoV antibody titres by indirect immunofluorescence assay. Results Follow-up data were available from 18 cats in week 24, from 15 cats in week 36 and from 14 cats in week 48 (after the start of treatment), respectively. Laboratory parameters remained stable after the end of the treatment, with undetectable blood viral loads (in all but one cat on one occasion). Recurrence of faecal FCoV shedding was detected in five cats. In four cats, an intermediate short-term rise in anti-FCoV antibody titres was detected. In total, 12 cats showed abdominal lymphadenomegaly during the follow-up period; four of them continuously during the treatment and follow-up period. Two cats developed mild neurological signs, compatible with feline hyperaesthesia syndrome, in weeks 36 and 48, respectively; however, FCoV RNA remained undetectable in blood and faeces, and no increase in anti-FCoV antibody titres was observed in these two cats, and the signs resolved. Conclusions and relevance Treatment with GS-441524 proved to be effective against FIP in both the short term as well as the long term, with no confirmed relapse during the 1-year follow-up period. Whether delayed neurological signs could be a long-term adverse effect of the treatment or associated with a ‘long FIP syndrome’ needs to be further evaluated

Curing cats with Feline Infectious Peritonitis with an oral multi-component drug containing GS-441524

Feline infectious peritonitis (FIP) caused by feline coronavirus (FCoV) is a common dis-ease in cats, fatal if untreated, and no effective treatment is currently legally available. The aim of this study was to evaluate efficacy and toxicity of the multi-component drug Xraphconn$^{®}$ in vitro and as oral treatment in cats with spontaneous FIP by examining survival rate, development of clinical and laboratory parameters, viral loads, anti-FCoV antibodies, and adverse effects. Mass spectrometry and nuclear magnetic resonance identified GS-441524 as an active component of Xraphconn$^{®}$. Eighteen cats with FIP were prospectively followed up while being treated orally for 84 days. Values of key parameters on each examination day were compared to values before treatment initiation using linear mixed-effect models. Xraphconn$^{®}$ displayed high virucidal activity in cell culture. All cats recovered with dramatic improvement of clinical and laboratory parameters and massive reduction in viral loads within the first few days of treatment without serious adverse effects. Oral treatment with Xraphconn$^{®}$ containing GS-441524 was highly effective for FIP without causing serious adverse effects. This drug is an excellent option for the oral treatment of FIP and should be trialed as potential effective treatment option for other severe coronavirus-associated diseases across species

Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE

Combined search for the quarks of a sequential fourth generation

Results are presented from a search for a fourth generation of quarks produced singly or in pairs in a data set corresponding to an integrated luminosity of 5 inverse femtobarns recorded by the CMS experiment at the LHC in 2011. A novel strategy has been developed for a combined search for quarks of the up and down type in decay channels with at least one isolated muon or electron. Limits on the mass of the fourth-generation quarks and the relevant Cabibbo-Kobayashi-Maskawa matrix elements are derived in the context of a simple extension of the standard model with a sequential fourth generation of fermions. The existence of mass-degenerate fourth-generation quarks with masses below 685 GeV is excluded at 95% confidence level for minimal off-diagonal mixing between the third- and the fourth-generation quarks. With a mass difference of 25 GeV between the quark masses, the obtained limit on the masses of the fourth-generation quarks shifts by about +/- 20 GeV. These results significantly reduce the allowed parameter space for a fourth generation of fermions.Comment: Replaced with published version. Added journal reference and DO