170 research outputs found
New Physics at the LHC. A Les Houches Report: Physics at TeV Colliders 2009 - New Physics Working Group
We present a collection of signatures for physics beyond the standard model
that need to be explored at the LHC. First, are presented various tools
developed to measure new particle masses in scenarios where all decays include
an unobservable particle. Second, various aspects of supersymmetric models are
discussed. Third, some signatures of models of strong electroweak symmetry are
discussed. In the fourth part, a special attention is devoted to high mass
resonances, as the ones appearing in models with warped extra dimensions.
Finally, prospects for models with a hidden sector/valley are presented. Our
report, which includes brief experimental and theoretical reviews as well as
original results, summarizes the activities of the "New Physics" working group
for the "Physics at TeV Colliders" workshop (Les Houches, France, 8-26 June,
2009).Comment: 189 page
Mapping interactions with the chaperone network reveals factors that protect against tau aggregation.
A network of molecular chaperones is known to bind proteins ('clients') and balance their folding, function and turnover. However, it is often unclear which chaperones are critical for selective recognition of individual clients. It is also not clear why these key chaperones might fail in protein-aggregation diseases. Here, we utilized human microtubule-associated protein tau (MAPT or tau) as a model client to survey interactions between ~30 purified chaperones and ~20 disease-associated tau variants (~600 combinations). From this large-scale analysis, we identified human DnaJA2 as an unexpected, but potent, inhibitor of tau aggregation. DnaJA2 levels were correlated with tau pathology in human brains, supporting the idea that it is an important regulator of tau homeostasis. Of note, we found that some disease-associated tau variants were relatively immune to interactions with chaperones, suggesting a model in which avoiding physical recognition by chaperone networks may contribute to disease
Component fractionation of wood-tar by column chromatography with the packing material of silica gel
New Physics at the LHC. A Les Houches Report: Physics at TeV Colliders 2009 - New Physics Working Group
We present a collection of signatures for physics beyond the standard model that need to be explored at the LHC. First, are presented various tools developed to measure new particle masses in scenarios where all decays include an unobservable particle. Second, various aspects of supersymmetric models are discussed. Third, some signatures of models of strong electroweak symmetry are discussed. In the fourth part, a special attention is devoted to high mass resonances, as the ones appearing in models with warped extra dimensions. Finally, prospects for models with a hidden sector/valley are presented. Our report, which includes brief experimental and theoretical reviews as well as original results, summarizes the activities of the "New Physics" working group for the "Physics at TeV Colliders" workshop (Les Houches, France, 8-26 June, 2009)
Combining functional weed ecology and crop stable isotope ratios to identify cultivation intensity: a comparison of cereal production regimes in Haute Provence, France and Asturias, Spain
This investigation combines two independent
methods of identifying crop growing conditions and husbandry
practices—functional weed ecology and crop stable
carbon and nitrogen isotope analysis—in order to assess
their potential for inferring the intensity of past cereal
production systems using archaeobotanical assemblages.
Present-day organic cereal farming in Haute Provence,
France features crop varieties adapted to low-nutrient soils
managed through crop rotation, with little to no manuring.
Weed quadrat survey of 60 crop field transects in this region
revealed that floristic variation primarily reflects
geographical differences. Functional ecological weed data
clearly distinguish the Provence fields from those surveyed
in a previous study of intensively managed spelt wheat in
Asturias, north-western Spain: as expected, weed ecological
data reflect higher soil fertility and disturbance in
Asturias. Similarly, crop stable nitrogen isotope values
distinguish between intensive manuring in Asturias and
long-term cultivation with minimal manuring in Haute
Provence. The new model of cereal cultivation intensity
based on weed ecology and crop isotope values in Haute
Provence and Asturias was tested through application to
two other present-day regimes, successfully identifying a
high-intensity regime in the Sighisoara region, Romania,
and low-intensity production in Kastamonu, Turkey. Application
of this new model to Neolithic archaeobotanical
assemblages in central Europe suggests that early farming
tended to be intensive, and likely incorporated manuring,
but also exhibited considerable variation, providing a finer
grained understanding of cultivation intensity than previously
available
Collider aspects of flavour physics at high Q
This review presents flavour related issues in the production and decays of
heavy states at LHC, both from the experimental side and from the theoretical
side. We review top quark physics and discuss flavour aspects of several
extensions of the Standard Model, such as supersymmetry, little Higgs model or
models with extra dimensions. This includes discovery aspects as well as
measurement of several properties of these heavy states. We also present public
available computational tools related to this topic.Comment: Report of Working Group 1 of the CERN Workshop ``Flavour in the era
of the LHC'', Geneva, Switzerland, November 2005 -- March 200
HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1
Recent studies have revealed that a mild increase in environmental temperature stimulates the growth of Arabidopsis seedlings by promoting biosynthesis of the plant hormone auxin. However, little is known about the role of other factors in this process. In this report we show that increased temperature promotes rapid accumulation of the TIR1 auxin co-receptor, an effect that is dependent on the molecular chaperone HSP90. In addition, we show that HSP90 and the co-chaperone SGT1 each interact with TIR1, confirming that TIR1 is an HSP90 client. Inhibition of HSP90 activity results in degradation of TIR1 and interestingly, defects in a range of auxin-mediated growth processes at lower as well as higher temperatures. Our results indicate that HSP90 and SGT1 integrate temperature and auxin signaling in order to regulate plant growth in a changing environment
Periodicities in the Daily Proton Fluxes from 2011 to 2019 Measured by the Alpha Magnetic Spectrometer on the International Space Station from 1 to 100 GV
We present the precision measurement of the daily proton fluxes in cosmic rays from May 20, 2011 to October 29, 2019 (a total of 2824 days or 114 Bartels rotations) in the rigidity interval from 1 to 100 GV based on 5.5×109 protons collected with the Alpha Magnetic Spectrometer aboard the International Space Station. The proton fluxes exhibit variations on multiple timescales. From 2014 to 2018, we observed recurrent flux variations with a period of 27 days. Shorter periods of 9 days and 13.5 days are observed in 2016. The strength of all three periodicities changes with time and rigidity. The rigidity dependence of the 27-day periodicity is different from the rigidity dependences of 9-day and 13.5-day periods. Unexpectedly, the strength of 9-day and 13.5-day periodicities increases with increasing rigidities up to ∼10 GV and ∼20 GV, respectively. Then the strength of the periodicities decreases with increasing rigidity up to 100 GV.</p
Sentiment-Focused Web Crawling
Sentiments and opinions expressed in Web pages towards objects, entities, and products constitute an important portion of the textual content available in the Web. In the last decade, the analysis of such content has gained importance due to its high potential for monetization. Despite the vast interest in sentiment analysis, somewhat surprisingly, the discovery of sentimental or opinionated Web content is mostly ignored. This work aims to fill this gap and addresses the problem of quickly discovering and fetching the sentimental content present in the Web. To this end, we design a sentiment-focused Web crawling framework. In particular, we propose different sentiment-focused Web crawling strategies that prioritize discovered URLs based on their predicted sentiment scores. Through simulations, these strategies are shown to achieve considerable performance improvement over general-purpose Web crawling strategies in discovery of sentimental Web content
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