23 research outputs found
Nucleation of Al3Zr and Al3Sc in aluminum alloys: from kinetic Monte Carlo simulations to classical theory
- Author
- A. Deschamps
- A. Perini
- A. Van der Ven
- A.R. Allnatt
- Christophe Sigli
- D. de Fontaine
- E. Clouet
- E. Nes
- E.A. Marquis
- Emmanuel Clouet
- F. Berthier
- F. Berthier
- F. Soisson
- G.M. Novotny
- J. Murray
- J.D. Robson
- J.M. Roussel
- J.M. Sanchez
- J.P. Perdew
- J.P. Simon
- J.R. Manning
- K. Binder
- K. Binder
- K.M. Carling
- K.M. Carling
- M. Asta
- M. Asta
- M. Athènes
- M. Methfessel
- M. Nastar
- M. Sluiter
- M.A. Novotny
- M.J. Stowell
- Maylise Nastar
- N. Ryum
- O. Le Bacq
- P. Mirold
- R. Kikuchi
- R.A. Ramos
- R.W. Hyland
- R.W. Hyland
- S.I. Fujikawa
- T. Hoshino
- T. Marumo
- T. Mohri
- V. Ozolins
- V.A. Shneidman
- Y. Le Bouar
- Y. Miura
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2004
- Field of study
Zr and Sc precipitate in aluminum alloys to form the compounds Al3Zr and
Al3Sc which for low supersaturations of the solid solution have the L12
structure. The aim of the present study is to model at an atomic scale this
kinetics of precipitation and to build a mesoscopic model based on classical
nucleation theory so as to extend the field of supersaturations and annealing
times that can be simulated. We use some ab-initio calculations and
experimental data to fit an Ising model describing thermodynamics of the Al-Zr
and Al-Sc systems. Kinetic behavior is described by means of an atom-vacancy
exchange mechanism. This allows us to simulate with a kinetic Monte Carlo
algorithm kinetics of precipitation of Al3Zr and Al3Sc. These kinetics are then
used to test the classical nucleation theory. In this purpose, we deduce from
our atomic model an isotropic interface free energy which is consistent with
the one deduced from experimental kinetics and a nucleation free energy. We
test di erent mean-field approximations (Bragg-Williams approximation as well
as Cluster Variation Method) for these parameters. The classical nucleation
theory is coherent with the kinetic Monte Carlo simulations only when CVM is
used: it manages to reproduce the cluster size distribution in the metastable
solid solution and its evolution as well as the steady-state nucleation rate.
We also find that the capillary approximation used in the classical nucleation
theory works surprisingly well when compared to a direct calculation of the
free energy of formation for small L12 clusters.Comment: submitted to Physical Review B (2004
ATLAS detector and physics performance: Technical Design Report, 1
- Author
- Abdinov O.B.
- Abolins M.
- Abramowicz H.
- Acerbi E.
- Ackermann K.
- Ackers M.
- Aderholz M.
- Ahlen S.
- Aielli G.
- Airapetian A.
- Akerman D.
- Akesson T.
- Akhmedov A.
- Akhoundov A.
- Akimov A.
- Alam S.
- Aleksa M.
- Aleppo M.
- Alessandria F.
- Alexa C.
- Alexander G.
- Alexandrov I.
- Alexeev G.
- Alforque S.
- Alikov B.
- Allport P.P.
- Almehed S.
- Aloisio A.
- Alviggi M.G.
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- Amako K.
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- Ambrosini G.
- Amelin D.V.
- Ammosov V.V.
- Amorim A.
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- Anderson K.
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- Publication venue
- Union of Concerned Scientists
- Publication date
- 01/01/1999
- Field of study
Sensing and responding to energetic stress: The role of the AMPK-PGC1α-NRF1 axis in control of mitochondrial biogenesis in fish
- Author
- Bremer
- Bremer
- Burkewitz
- C.D. Moyes
- Camacho
- Carling
- Chen
- Choi
- Craig
- Dhar
- Duggan
- Evans
- Fernandez-Marcos
- Fogarty
- Frier
- Fuentes
- Handschin
- Hardie
- Holmes
- Jibb
- Jäger
- K. Bremer
- K.M. Kocha
- Larsson
- LeMoine
- LeMoine
- Little
- Magnoni
- Magnoni
- Narkar
- Ohno
- Ongwijitwat
- Orczewska
- Pang
- Pfaffl
- Poyton
- Puigserver
- R Core Team
- Rantanen
- Scarpulla
- Scarpulla
- Stensløkken
- T. Snider
- Tang
- Virbasius
- Viscomi
- Winder
- Woods
- Wu
- Xu
- Zitomer
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Design and validation of an observational instrument for technical and tactical actions in beach volleyball
- Author
- Anguera M.T.
- Behar J.
- Blanco A.
- Bulger S.M.
- Burchuk M.
- Carling C.
- Coleman J.E.
- Elosua P.
- Eom H.J.
- Eom H.J.
- Escurra L.
- Glazier P.S.
- Homberg S.
- Hughes M.D.
- Hughes M.D.
- Kimberlin C.L.
- Knudson D.V.
- Lebed F.
- Liebermann D.G.
- Marcelino R.
- McCall G. J.
- McGarry T.
- Merino C.
- Newell K.M.
- Ntoumanis N.
- Padilla J.L.
- Palao J.M.
- Palao J.M.
- Palao J.M.
- Penfield R.D.
- Selinger A.
- Sykes R.E.
- Tabachnick B.G.
- Trochim W.
- Zhu W.
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Metabolomics-edited transcriptomics analysis of Se anticancer action in human lung cancer cells
- Author
- Andrew N. Lane
- C. Ip
- D. Carling
- D. Lu
- D. Mustacich
- D.G. Gadian
- E.S.J. Arner
- G.F. Merrill
- G.N. Schrauzer
- H. Schenk
- H.E. Ganther
- J.C. Aledo
- J.E. Lindsley
- K. Becker
- K.C.M. Verhoeckx
- K.M. Brindle
- L. Bandura
- L. Yan
- L. Yan
- L.C. Clark
- L.E. Huang
- Laura L. Bandura
- M.A. Sanjuan
- M.J. Bonneau
- M.J. Gradwell
- M.Y. Hirai
- Richard M. Higashi
- S.A. Farber
- T. Sasada
- T. Tanaka
- T.W.-M. Fan
- T.W.-M. Fan
- T.W.-M. Fan
- T.W.-M. Fan
- T.W.-M. Fan
- T.W.-M. Fan T.
- Teresa W. M. Fan
- V. Vasta
- W.-N.P. Lee
- W.H.M. Heijne
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Standard doses of the oral proton pump inhibitors are clinically equivalent: A comparison
- Author
- A. Gillessen
- A. Vcev
- A.B.R. Thomson
- A.B.R. Thomson
- A.S. Mee
- Alan B. R. Thomson
- B. Thjodleifsson
- C. Chen
- C.J. Mulder
- C.J. Rensburg Van
- C.P.M. Dekkers
- C.W. Howden
- C.W. Howden
- D. Armstrong
- D. Armstrong
- D. Castell
- D. Glatzel
- D. Jasperson
- D.O. Castell
- D.W. Burget
- E.F. Verdu
- F. Vicari
- H. Mönnikes
- H.G. Dammann
- I.M. Gralnek
- J. Corallo
- J. Hotz
- J. Huang
- J. Labenz
- J. Mössner
- J. Mössner
- J.G. Hatlebakk
- J.P. Petite
- K. Lauritsen
- K.D. Bardhan
- K.G. Tolman
- K.M. Fock
- K.R. McQuaid
- L. Carling
- M.B. Fennerty
- M.S. McDonagh
- N.J. Bell
- N.J. Vakil
- R. Corinaldesi
- R. Seensalu
- R.M. Klok
- S.J. Edwards
- S.J. Edwards
- U.A. Meyer
- V. Stanghellini
- V. Stanghellini
- W. Chey
- W. Kromer
- W. Wang
- W.P. Geus
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Mycorrhizae In The Integrated Pest And Disease Management
- Author
- A. Elsen
- A. Hodge
- A. Torres-Barragán
- A. Trotta
- A. Vivas
- A.K. Suresh
- A.V. Brock
- B Hause
- B. Giri
- B. Munzenberger
- C. Azcó-Aguilar
- C. Calvet
- C. Calvet
- C. Cordier
- C. Cordier
- C. Guillon
- C. Keel
- C. Morin
- C. Vigo
- C. Voisard
- C.A. Ryan
- C.B. Mcallister
- D. Atkinson
- D.E. Carling
- D.J. Burke
- D.M. Sylvia
- D.N. Dowling
- E. Gamalero
- E.A. Curl
- E.E Farmer
- F.T. Davies Jr
- F.T. Davies Jr
- G Lingua
- G. Andrade
- G. Andrade
- G. Bestel-Corre
- G. Bestel-Corre
- G. Défago
- G.H. Dar
- G.S. Smith
- H. Founoune
- H. Saleh
- H.H. Kope
- I der Von Weid
- I. Chet
- I. Garmendia
- I. Garmendia
- I. Garmendia
- I. Garmendia
- J. Garbaye
- J. Hallmann
- J. Huang
- J. Pinochet
- J.F. Johansson
- J.H. O’Bannon
- J.M. Barea
- J.M. Barea
- J.M. Barea
- J.M. Barea
- J.M. Ruiz-Lozano
- J.M. Ruiz-Lozano
- J.M. Trappe
- J.R. Norman
- J.R. Norman
- J.W. Deacon
- J.W. Whipps
- K. Heungens
- K. Thygesen
- K.G. Mukerji
- K.G. Mukerji
- K.G. Mukerji
- K.G. Mukerji
- K.G. Mukerji
- K.G. Mukerji
- K.G. Mukerji
- K.M. Cooper
- K.M. Thomson Cason
- L. Lanfranco
- L.A. Harrier
- L.C. Duchesne
- L.C. Duchesne
- L.C. Duchesne
- L.C. Duchesne
- L.C. Duchesne
- L.C. Duchesne
- L.J. Francl
- L.J.C. Xavier
- L.L. Gao
- M. Bansal
- M. Bansal
- M. Bansal
- M. Caron
- M. Filion
- M. Filion
- M. Fritz
- M. St-Arnaud
- M. St-Arnaud
- M.A. Altieri
- M.C. Jaizme-Vega
- M.J Pozo
- M.J Pozo
- M.J. Pozo
- M.P. Sharma
- M.P. Sharma
- M.P. Sharma
- M.S. Rao
- M.S. Rao
- N. Goicoechea
- N. Vassilev
- O. Shaul
- P. Marschner
- P. Salzer
- P. Shanahan
- P.M. Diedhiou
- R. Gupta
- R. Kapoor
- R. Singh
- R. Utkhede
- R. Zaidi
- R.A. Creelman
- R.C. Summerbell
- R.G. Linderman
- R.G. Linderman
- R.G. Linderman
- R.G. Linderman
- R.G. Linderman
- R.J. Cook
- R.J. Liu
- R.M. Augé
- R.M. Boddey
- R.S. Hussey
- R.S. Zeng
- S. Declerck
- S. Demir
- S. Slezack
- S. Slezack
- S. Slezack
- S. Timonen
- S.B. Chincholkar
- S.E Smith
- S.F. Hwang
- S.J. Grayston
- S.W. Budi
- T. Benitez
- T. Gasper
- T.C. Paulitz
- T.C. Paulitz
- T.L. Wacker
- V. Artursson
- V. Artursson
- V. Bianciotto
- V. Bianciotto
- V. Bianciotto
- V. Bianciotto
- W.E Durrant
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2007
- Field of study
Dysregulation of RNA polymerase I transcription during disease
- Author
- Abidi
- Ali
- Andersen
- Arabi
- Assfalg
- Ayrault
- Bakshi
- Ball
- Bergstralh
- Bertwistle
- Bierhoff
- Birch
- Blyth
- Boisvert
- Boisvert
- Boisvert
- Boisvert
- Bose
- Boulon
- Bradsher
- Brady
- Brandenburger
- Brandenburger
- Brown
- Bywater
- Carling
- Cavanaugh
- Chan
- Chaudhary
- Chein
- Chen
- Cheng
- Chester
- Chi
- Chi
- Chiabrando
- Chinnam
- Cho
- Choesmel
- Chu
- Colombo
- Conte
- Dang
- Dauwerse
- Dawson
- Deng
- Ding
- Dixon
- Dixon
- Dixon
- Dominguez-Brauer
- Drygin
- Drygin
- Drygin
- Duan
- Dutt
- E. Sanij
- Edery
- Efeyan
- Eilers
- Emmott
- Fanzani
- Feng
- Flygare
- Fousteri
- Freed
- Freed
- Freed-Pastor
- Frescas
- Frontini
- Fumagalli
- Fumagalli
- Fumagalli
- Ganapathi
- Gomez-Roman
- Gonugunta
- Goodfellow
- Gorski
- Grandori
- Greenman
- Grierson
- Grummt
- Hannan
- Hannan
- Hannan
- Hannan
- Hannan
- Hannan
- Hannan
- Hannan
- Hannan
- Hannan
- Hardie
- Hardie
- Hein
- Henley
- Hershey
- Hill
- Hirschler-Laszkiewicz
- Hoppe
- Horiuchi
- Huang
- Hundsdorfer
- Ide
- Johnson
- Jones
- K.M. Hannan
- Kaneko
- Kang
- Kenneth
- Kleine-Kohlbrecher
- Kong
- Korgaonkar
- Kraft
- Kruhlak
- Kurki
- Kuwahara
- L.I. Rothblum
- Laferte
- Lake
- Larminie
- Latini
- Laugel
- Laumonnier
- Lebedev
- Lebel
- Lempiainen
- Lessard
- Lessard
- Li
- Li
- Li
- Lin
- Lisik
- Liu
- Liu
- Loenarz
- Lombard
- Lutomska
- Luyken
- Machida
- Manning
- Mansouri
- Mariappan
- Marszalek-Kruk
- Matheu
- Matsson
- Mayer
- McArthur
- McDermott
- McStay
- Meani
- Melvin
- Melvin
- Meraner
- Meyer
- Miller
- Miyake
- Moniz
- Monnich
- Morgan
- Muth
- Najib
- Narla
- Narla
- Natale
- Negrini
- Nousbeck
- Onyezili
- Pandit
- Paredes
- Patel
- Pellagatti
- Pelletier
- Piazza
- Pierre
- Pierre
- Polager
- Poomsawat
- Poortinga
- Poortinga
- Popov
- Populo
- Powers
- Pratilas
- Qi
- Qiu
- R.B. Pearson
- R.D. Hannan
- Ramos-Echazabal
- Rau
- Reikvam
- Ridanpaa
- Roberts
- Rohini
- Romeo
- Rosello-Lleti
- Rossi
- Ruwhof
- Ruzzene
- Sabapathy
- Sakai
- Sala
- Sanij
- Sanij
- Schawalder
- Schmitz
- Sears
- Shenoy
- Sheppard
- Sherr
- Shiratori
- Shiue
- Shiue
- Sieff
- Siehl
- Silva
- Solomon
- Soucek
- Stefanovsky
- Stefanovsky
- Stone
- Sun
- Tang
- Tawfic
- Thiel
- Thompson
- Thway
- Tikoo
- Trainor
- Uemura
- Uhlen
- Valdez
- Vallon
- van Koningsbruggen
- van Riggelen
- Varlakhanova
- Velkova
- Vettel
- Voit
- Voit
- Voit
- von Walden
- Wang
- Wang
- White
- White
- White
- Williamson
- Wu
- Wu
- Xiao
- Yankiwski
- Yoon
- Young
- Yu
- Yuan
- Yuan
- Yuan
- Yue
- Zhai
- Zhang
- Zhang
- Zhang
- Zhang
- Zhang
- Zhao
- Zhong
- Zhou
- Zhu
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/03/2013
- Field of study
Transcription of the ribosomal RNA genes by the dedicated RNA polymerase I enzyme and subsequent processing of the ribosomal RNA are fundamental control steps in the synthesis of functional ribosomes.Dysregulation of Pol I transcription and ribosome biogenesis is linked to the etiology of a broad range of human diseases. Diseases caused by loss of function mutations in the molecular constituents of the ribosome, or factors intimately associated with RNA polymerase I transcription and processing are collectively termed ribosomopathies. Ribosomopathies are generally rare and treatment options are extremely limited tending to be more palliative than curative. Other more common diseases are associated with profound changes in cellular growth such as cardiac hypertrophy, atrophy or cancer. In contrast to ribosomopathies, altered RNA polymerase I transcriptional activity in these diseases largely results from dysregulated upstream oncogenic pathways or by direct modulation by oncogenes or tumor suppressors at the level of the RNA polymerase I transcription apparatus itself. Ribosomopathies associated with mutations in ribosomal proteins and ribosomal RNA processing or assembly factors have been covered by recent excellent reviews. In contrast, here we review our current knowledge of human diseases specifically associated with dysregulation of RNA polymerase I transcription and its associated regulatory apparatus, including some cases where this dysregulation is directly causative in disease. We will also provide insight into and discussion of possible therapeutic approaches to treat patients with dysregulated RNA polymerase I transcription. This article is part of a Special Issue entitled: Transcription by Odd Pols
Simulating conversations: The communion game
- Author
- A. Turing
- A. Waibel
- A.G. Hobbs
- A.P. Huxor
- B. Katz
- B. Malinowski
- B. Shanon
- C. Carling
- C. Karelis
- C. Trevarthen
- C. Trevarthen
- C. Wheddon
- C.E. Shannon
- C.J.C.H. Watkins
- C.K. Ogden
- D. Crystal
- D. Jacquette
- D. McDermott
- D. Michie
- D. Michie
- D. Sperber
- D.B. Lenat
- D.H. Klatt
- F. Saussure de
- G. Alper
- G. Bateson
- G. Sommerhoff
- H. Giles
- H.L. Dreyfus
- J. `t Hart
- J. Laver
- J. Laver
- J. Locke
- J. Lyons
- J. Weizenbaum
- J. Weizenbaum
- J.J. Gumperz
- J.J. Üxküll
- J.L. Mey
- J.R. Krebs
- J.R. Lucas
- J.R. Searle
- Jerry Fodor
- K. Gunderson
- K. Gödel
- K. Sims
- K.M. Colby
- L. Bloomfield
- L. Hauser
- L. Wittgenstein
- L.S. Hultzén
- M. Steedman
- M.A.K. Halliday
- M.A.K. Halliday
- N. Block
- N. Block
- N. Chomsky
- N. Chomsky
- N. Chomsky
- N. Chomsky
- N.J. Nilsson
- P. Bieri
- P. Slezak
- P. Smolensky
- P.F. Strawson
- P.H. Matthews
- P.P.G. Bateson
- P.R. Martin
- R. Harris
- R. Harris
- R. Harré
- R. Penrose
- R. Wilensky
- R.A. Brooks
- R.A. Brooks
- R.G. Schank
- R.M. French
- R.S. Sutton
- S. Harnad
- S. Harnad
- S. J. Cowley
- S. M. Farabaugh
- S. Prevost
- S.C. Levinson
- S.J. Cowley
- S.M. Omohundro
- S.M. Shieber
- T. Lowerre
- T. Winograd
- T. Winograd
- W.F. Clocksin
- W.H. Thorpe
- W.S. Allen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Specific erosional and depositional processes in a pleistocene subglacial tunnel in the wielkopolska region, poland
- Author
- Andrews J.T.
- Batalla R.J.
- Best J.L.
- Beverage J.P.
- Black R.F.
- Bogardi J.
- Boulton G.S.
- Boulton G.S.
- Brennand T.A.
- Brennand T.A.
- Brennand T.A.
- Brierley G.J.
- Brodzikowski K.
- Burke M.J.
- Burke M.J.
- Burn C.R.
- Butrym J.
- Carling P.A.
- Costa J.E.
- Curray J.R.
- Delaney C.
- Delaney C.
- Delaney C.
- Dowdeswell J.A.
- Fard A.M.
- Fard A.M.
- Foley M.G.
- French H.M
- French H.M.
- French H.M.
- French H.M.
- Gill W.D.
- Goździk J.
- Gruszka B.
- Gruszka B.
- Harry D.G.
- Hartley A.J.
- Huddart D.
- Kasse C.
- Kjær K.H.
- Knight P.G.
- Kotov A.N.
- Krupa A.
- Li D.
- Lowe D.R.
- Lowe D.R.
- Lowe D.R.
- Lunkka J.P.
- Maizels J.
- Mark D.M.
- Marks L.
- Meyer G.A.
- Miall A.D.
- Mycielska‐dowgiałło E.
- Nevin C.M.
- Novak I.D.
- Piotrowski J.A.
- Pisarska‐jamroży M.
- Pisarska‐jamroży M.
- Pissart A.
- Przybylski B.
- Ringrose S.
- Roman M.
- Rotnicki K.
- Rotnicki K.
- Russell A.J.
- Russell A.J.
- Ruszczyńska‐szenajch H.
- Saunderson H.C.
- Saunderson H.C.
- Shaw J.
- Shulmeister J.
- Sohn Y.K.
- Stankowski W.
- Stromberg S.G.
- Sundborg A.
- Svendsen J.
- Svensson H.
- Syverson K.M.
- Udden J. A.
- Van huissteden J.
- Van loon A.J.
- Van loon A.J.
- Van loon A.J.
- Vrolijk P.J.
- Warren W.P.
- Weaver L.
- Wentworth C.K.A.
- Williams G.P.
- Zieliński T.
- Publication venue
- 'Wiley'
- Publication date
- Field of study