18 research outputs found

    3D electrical resistivity of Gran Canaria island using magnetotelluric data

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    Gran Canaria, one of the two main islands of the Canary Archipelago off NW Africa, has been volcanically active for at least 15 million years. The island went through several volcanic cycles that varied greatly in composition and extrusive and intrusive activity. The complex orography of the island has excluded extensive land geophysical surveys on the island. A review of the available geophysical information on the island shows that it has been obtained mainly through marine and airborne geophysical surveys. A new dataset comprising 100 magnetotelluric soundings acquired on land has been used to obtain the first 3D electrical resistivity model of the island at crustal scale. The model shows high resistivity values close to the surface in the exposed Tejeda Caldera that extends at depth to the SE cutting the islands in half. Outside the inferred limits of the Tejeda Caldera the 3D model shows low resistivity values that could be explained by hydrothermal alteration at deeper levels and the presence of marine saltwater intrusion at shallower levels near the coast. The presence of unconnected vertical-like structures, with very low resistivity (<10 ohm m) could be associated to small convective cells is confirmed by the sensitivity analysis carried out in the present study. Those structures are the most likely candidates for a detailed analysis in order to determine their geothermal economic potential. A comprehensive review of existing geophysical data and models of Gran Canaria island and their comparison with the new 3D electrical resistivity model is presented.</p

    Exploring the Factors Controlling the Error Characteristics of the Surface Water and Ocean Topography Mission Discharge Estimates

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    The Surface Water and Ocean Topography (SWOT) satellite mission will measure river width, water surface elevation, and slope for rivers wider than 50–100 m. SWOT observations will enable estimation of river discharge by using simple flow laws such as the Manning-Strickler equation, complementing in situ streamgages. Several discharge inversion algorithms designed to compute unobserved flow law parameters (e.g., friction coefficient and bathymetry) have been proposed, but to date, a systematic assessment of factors controlling algorithm performance has not been conducted. Here, we assess the performance of the five algorithms that are expected to be used in the construction of the SWOT product. To perform this assessment, we used synthetic SWOT observations created with hydraulic model output corrupted with SWOT-like error. Prior information provided to the algorithms was purposefully limited to an estimate of mean annual flow (MAF), designed to produce a “worst case” benchmark. Prior MAF error was an important control on algorithm performance, but discharge estimates produced by the algorithms are less biased than the MAF; thus, the discharge algorithms improve on the prior. We show for the first time that accuracy and frequency of remote sensing observations are less important than prior bias, hydraulic variability among reaches, and flow law accuracy in governing discharge algorithm performance. The discharge errors and error sensitivities reported herein are a bounding benchmark, representing worst possible expected errors and error sensitivities. This study lays the groundwork to develop predictive power of algorithm performance, and thus map the global distribution of worst-case SWOT discharge accuracy

    Hyaluronidase enhances the activity of adriamycin in breast cancer models in vitro and in vivo

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    The effect of hyaluronidase and a combination of hyaluronidase with Adriamycin was investigated on several breast cancer models in vitro and in vivo. In vitro enzyme treatment (using concentrations up to 80,000 IU/1) of murine (MXT-, MXT +/-, and MXT+) and human (MCF-7, ZR-75-1 and T-47-D) breast cancer cell lines did not inhibit tumour cell proliferation (measured by a kinetic crystal violet assay) in either case. Although high-dose hyaluronidase (1.2 x 10(6) IU/kg) was ineffective, when administered peritumourally to the MXT M3.2 mammary carcinoma of the B6D2F1 mouse, it is remarkable that five "megadoses" were excellently tolerated. However, the antineoplastic activity of Adriamycin against the oestrogen-receptor-positive variant of the MXT tumour was significantly enhanced by combination with concentrations of hyaluronidase that were inactive per se, both in vitro and in vivo. Interestingly, the enhancement of the in vivo antitumour activity was not compromised by toxic side-effects

    3D electrical resistivity of Gran Canaria island using magnetotelluric data

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    Highlights • New broad band magnetotelluric data covering the whole Gran Canaria island. • First 3D electrical resistivity model of Gran Canaria island at crustal scale. • Low resistivity anomalies found may be of interest for geothermal exploitation. • 3D electrical resitivity shows a good correlation with other geophysical data available at crustal scale. Abstract Gran Canaria, one of the two main islands of the Canary Archipelago off NW Africa, has been volcanically active for at least 15 million years. The island went through several volcanic cycles that varied greatly in composition and extrusive and intrusive activity. The complex orography of the island has excluded extensive land geophysical surveys on the island. A review of the available geophysical information on the island shows that it has been obtained mainly through marine and airborne geophysical surveys. A new dataset comprising 100 magnetotelluric soundings acquired on land has been used to obtain the first 3D electrical resistivity model of the island at crustal scale. The model shows high resistivity values close to the surface in the exposed Tejeda Caldera that extends at depth to the SE cutting the islands in half. Outside the inferred limits of the Tejeda Caldera the 3D model shows low resistivity values that could be explained by hydrothermal alteration at deeper levels and the presence of marine saltwater intrusion at shallower levels near the coast. The presence of unconnected vertical-like structures, with very low resistivity (<10 ohm m) could be associated to small convective cells is confirmed by the sensitivity analysis carried out in the present study. Those structures are the most likely candidates for a detailed analysis in order to determine their geothermal economic potential. A comprehensive review of existing geophysical data and models of Gran Canaria island and their comparison with the new 3D electrical resistivity model is presented

    Estimation of Multiple Inflows and Effective Channel by Assimilation of Multi-satellite Hydraulic Signatures: The Ungauged Anabranching Negro River

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    International audienceWith the upcoming SWOT satellite mission, which should provide spatially dense river surface elevation, width and slope observations globally, comes the opportunity to assimilate such data into hydrodynamic models, from the reach scale to the hydrographic network scale. Based on the HiVDI (Hierarchical Variational Discharge Inversion) modeling strategy (Larnier et al. [#Larnier2019]), this study tackles the forward and inverse modeling capabilities of distributed channel parameters and multiple inflows (in the 1D Saint-Venant model) from multisatellite observations of river surface. It is shown on synthetic cases that the estimation of both inflows and distributed channel parameters (bathymetry-friction) is achievable with a minimum spatial observability between inflows as long as their hydraulic signature is sampled. Next, a real case is studied: 871 km of the Negro river (Amazon basin) including complex multichannel reaches, 21 tributaries and backwater controls from major confluences. An effective modeling approach is proposed using (i) WS elevations from ENVISAT data and dense in situ GPS flow lines (Moreira [#DanielPhD]), (ii) average river top widths from optical imagery (Pekel et al. [#Pekel_Nature]), (iii) upstream and lateral flows from the MGB large-scale hydrological model (Paiva et al. [#paiva2013]). The calibrated effective hydraulic model closely fits satellite altimetry observations and presents real like spatial variabilities; flood wave propagation and water surface observation frequential features are analyzed with identifiability maps following Brisset et al. [#Brisset_2018]. Synthetic SWOT observations are generated from the simulated flowlines and allow to infer model parameters (436 effective bathymetry points, 17 friction patches and 22 upstream and lateral hydrographs) given hydraulically coherent prior parameter values. Inferences of channel parameters carried out on this fine hydraulic model applied at a large scale give satisfying results using noisy SWOT-like data at reach scale. Inferences of spatially distributed temporal parameters (lateral inflows) give satisfying results as well, with even relatively small scale hydrograph variations being inferred accurately on this long reach. This study brings insights in: (i) the hydraulic visibility of multiple inflows hydrographs signature at large scale with SWOT; (ii) the simultaneous identifiability of spatially distributed channel parameters and inflows by assimilation of satellite altimetry data; (iii) the need for prior information; (iv) the need to further tailor and scale network hydrodynamic models and assimilation methods to improve the fusion of multisource information and potential information feedback to hydrological modules in integrated chains
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