Prescription pattern of drugs in ENT outpatient department of tertiary care teaching hospital

Background: Diseases of the ear, nose and throat (ENT) are common among general population affecting all age groups and accounts for most of the drugs prescribed and used. The aim of the study is to assess the prescription pattern of drugs in ENT outpatient department in a tertiary care teaching hospital.Methods: A prospective observational study was conducted from December 2017 to May 2018 in the ENT OPD (Outpatient department) at Pt. J.N.M. Medical College and associated Dr. B.R. Ambedkar Memorial Hospital, Raipur. Data were collected in a proforma and evaluated.Results: A total of 313 prescriptions were analysed. Most of the patients (40.89%) belonged to 13 - 35 years age group.185 patients (59.10%) were male and 128 patients were females (40.90%). A total of 1003 drugs were prescribed. The average number of drugs per prescription was 3.2. Most common class of drugs prescribed was antimicrobials (24.42%), followed by H1 antihistaminics (18.84%), antiulcer drugs (15.55%) and nonsteroidal anti-inflammatory (NSAIDs) drugs (14.35%). The average number of antimicrobials per prescription was 0.78. One or two antimicrobials were prescribed in 202 prescriptions (64.53%). The most common prescribed antimicrobial was of Penicillin group (64.89%) followed by Fluoroquinolone (25.71%). The most common prescribed route of drug administration was oral route (81.35%). The most common prescribed dosage form was tablets (74.87%). FDC constituted 24.62% of prescribed drugs.Conclusions: The study revealed that the most common class of drug prescribed was antimicrobials followed by H1 antihistaminics, antiulcer drugs and NSAIDS

Synthesis and antitubercular activity of novel thiazolidinone derivatives

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Utility of Fine Needle Aspiration Cytology in Evaluation of Breast Lesions.

Objectives: FNAC(Fine needle aspiration cytology) of the breast lesion is a simple, cost effective and less traumatic screening procedure that is valuable for distinguishing non-neoplastic lesions from neoplastic lesions. The aim of the present study was to correlate cytological findings with histopathological findings and to determine the accuracy of FNAC in the diagnosis of breast lesions. Methods: A Retrospective study of total of 200 breast aspirates from January 2015 to May 2015 in pathology department, of B.J.M.C. civil hospital Ahmedabad was done and Histo-cytological correlations were obtained in 80 cases. Results: The statistical analysis showed high sensitivity (92.1%) and specificity (100%) of FNAC in breast lesions, with Positive Predictive Value (PPV) and the Negative Predictive Value (NPV) being 100% and 93.33% respectively. The diagnostic accuracy was found to be 98.5%. Conclusion: FNAC of breast is simple, cost effective and less traumatic method for diagnosis of breast lesions. It can be carried out safely as a preoperative diagnosis method on OPD basis. It is a highly sensitive and specific method so it can be recommended for the diagnosis of suspicious breast lump