129 research outputs found
Neural network parametrization of spectral functions from hadronic tau decays and determination of QCD vacuum condensates
The spectral function is determined from ALEPH and OPAL data
on hadronic tau decays using a neural network parametrization trained to retain
the full experimental information on errors, their correlations and chiral sum
rules: the DMO sum rule, the first and second Weinberg sum rules and the
electromagnetic mass splitting of the pion sum rule. Nonperturbative QCD vacuum
condensates can then be determined from finite energy sum rules. Our method
minimizes all sources of theoretical uncertainty and bias producing an estimate
of the condensates which is independent of the specific finite energy sum rule
used. The results for the central values of the condensates and are
both negative.Comment: 29 pages, 18 ps figure
Dynamics of air transport networks: A review from a complex systems perspective
Air transport systems are highly dynamic at temporal scales from minutes to years. This dynamic behavior not only characterizes the evolution of the system but also affect the system's functioning. Understanding the evolutionary mechanisms is thus fundamental in order to better design optimal air transport networks that benefits companies, passengers and the environment. In this review, we briefly present and discuss the state-of-the-art on time-evolving air transport networks. We distinguish the structural analysis of sequences of network snapshots, ideal for long-term network evolution (e.g. annual evolution), and temporal paths, preferred for short-term dynamics (e.g. hourly evolution). We emphasize that most previous research focused on the first modeling approach (i.e. long-term) whereas only a few studies look at high-resolution temporal paths. We conclude the review highlighting that much research remains to be done, both to apply already available methods and to develop new measures for temporal paths on air transport networks. In particular, we identify that the study of delays, network resilience and optimization of resources (aircraft and crew) are critical topics
Atomic X-ray Spectroscopy of Accreting Black Holes
Current astrophysical research suggests that the most persistently luminous
objects in the Universe are powered by the flow of matter through accretion
disks onto black holes. Accretion disk systems are observed to emit copious
radiation across the electromagnetic spectrum, each energy band providing
access to rather distinct regimes of physical conditions and geometric scale.
X-ray emission probes the innermost regions of the accretion disk, where
relativistic effects prevail. While this has been known for decades, it also
has been acknowledged that inferring physical conditions in the relativistic
regime from the behavior of the X-ray continuum is problematic and not
satisfactorily constraining. With the discovery in the 1990s of iron X-ray
lines bearing signatures of relativistic distortion came the hope that such
emission would more firmly constrain models of disk accretion near black holes,
as well as provide observational criteria by which to test general relativity
in the strong field limit. Here we provide an introduction to this phenomenon.
While the presentation is intended to be primarily tutorial in nature, we aim
also to acquaint the reader with trends in current research. To achieve these
ends, we present the basic applications of general relativity that pertain to
X-ray spectroscopic observations of black hole accretion disk systems, focusing
on the Schwarzschild and Kerr solutions to the Einstein field equations. To
this we add treatments of the fundamental concepts associated with the
theoretical and modeling aspects of accretion disks, as well as relevant topics
from observational and theoretical X-ray spectroscopy.Comment: 63 pages, 21 figures, Einstein Centennial Review Article, Canadian
Journal of Physics, in pres
Key Issues for Determining the Exploitable Water Resources in a Mediterranean River Basin
[EN] One of the major difficulties in water planning is to determine the water availability in a water resource system in order to distribute water sustainably. In this paper, we analyze the key issues for determining the exploitable water resources as an indicator of water availability in a Mediterranean river basin. Historically, these territories are characterized by heavily regulated water resources and the extensive use of unconventional resources (desalination and wastewater reuse); hence, emulating the hydrological cycle is not enough. This analysis considers the Jucar River Basin as a case study. We have analyzed the different possible combinations between the streamflow time series, the length of the simulation period and the reliability criteria. As expected, the results show a wide dispersion, proving the great influence of the reliability criteria used for the quantification and localization of the exploitable water resources in the system. Therefore, it is considered risky to provide a single value to represent the water availability in the Jucar water resource system. In this sense, it is necessary that policymakers and stakeholders make a decision about the methodology used to determine the exploitable water resources in a river basin. (C) 2014 Elsevier B.V. All rights reserved.The authors wish to thank the Confederacion Hidrografica del Jucar (Spanish Ministry of the Environment) for the data provided in developing this study and the Spanish Ministry of Economy and Competitiveness for its financial support through the projects SCARCE (Consolider-Ingenio 2010 CSD2009-00065) and NUTEGES (CGL2012-34978). We also value the support provided by the European Community's Seventh Framework Program in financing the projects DROUGHT-R82SPI (FP7-ENV-2011, 282769), ENHANCE (FP7-ENV-2012, 308438), WAMCD (EC-DG Environment No. 07.0329/2013/671291/ SUB/ENV.C1) and LIFE ALBUFERA (LIFE12 ENV/ES/000685).Pedro Monzonís, M.; Ferrer Polo, FJ.; Solera Solera, A.; Estrela Monreal, T.; Paredes Arquiola, J. (2015). Key Issues for Determining the Exploitable Water Resources in a Mediterranean River Basin. Science of the Total Environment. 503-504:319-328. https://doi.org/10.1016/j.scitotenv.2014.07.042S319328503-50
Trends and outcome of neoadjuvant treatment for rectal cancer: A retrospective analysis and critical assessment of a 10-year prospective national registry on behalf of the Spanish Rectal Cancer Project
Introduction: Preoperative treatment and adequate surgery increase local control in rectal cancer. However, modalities and indications for neoadjuvant treatment may be controversial. Aim of this study was to assess the trends of preoperative treatment and outcomes in patients with rectal cancer included in the Rectal Cancer Registry of the Spanish Associations of Surgeons.
Method: This is a STROBE-compliant retrospective analysis of a prospective database. All patients operated on with curative intention included in the Rectal Cancer Registry were included. Analyses were performed to compare the use of neoadjuvant/adjuvant treatment in three timeframes: I)2006–2009; II)2010–2013; III)2014–2017. Survival analyses were run for 3-year survival in timeframes I-II.
Results: Out of 14, 391 patients, 8871 (61.6%) received neoadjuvant treatment. Long-course chemo/radiotherapy was the most used approach (79.9%), followed by short-course radiotherapy ± chemotherapy (7.6%). The use of neoadjuvant treatment for cancer of the upper third (15-11 cm) increased over time (31.5%vs 34.5%vs 38.6%, p = 0.0018). The complete regression rate slightly increased over time (15.6% vs 16% vs 18.5%; p = 0.0093); the proportion of patients with involved circumferential resection margins (CRM) went down from 8.2% to 7.3%and 5.5% (p = 0.0004). Neoadjuvant treatment significantly decreased positive CRM in lower third tumors (OR 0.71, 0.59–0.87, Cochrane-Mantel-Haenszel P = 0.0008). Most ypN0 patients also received adjuvant therapy. In MR-defined stage III patients, preoperative treatment was associated with significantly longer local-recurrence-free survival (p < 0.0001), and cancer-specific survival (p < 0.0001). The survival benefit was smaller in upper third cancers.
Conclusion: There was an increasing trend and a potential overuse of neoadjuvant treatment in cancer of the upper rectum. Most ypN0 patients received postoperative treatment. Involvement of CRM in lower third tumors was reduced after neoadjuvant treatment. Stage III and MRcN + benefited the most
Continuing outcomes relevant to Evista:Breast cancer incidence in postmenopausal osteoporotic women in a randomized trial of Raloxifene
Perfil de ácidos graxos e teor de colesterol de mortadela elaborada com óleos vegetais
On the sensitivity of the HAWC observatory to gamma-ray bursts
We present the sensitivity of HAWC to Gamma Ray Bursts (GRBs). HAWC is a very
high-energy gamma-ray observatory currently under construction in Mexico at an
altitude of 4100 m. It will observe atmospheric air showers via the water
Cherenkov method. HAWC will consist of 300 large water tanks instrumented with
4 photomultipliers each. HAWC has two data acquisition (DAQ) systems. The main
DAQ system reads out coincident signals in the tanks and reconstructs the
direction and energy of individual atmospheric showers. The scaler DAQ counts
the hits in each photomultiplier tube (PMT) in the detector and searches for a
statistical excess over the noise of all PMTs. We show that HAWC has a
realistic opportunity to observe the high-energy power law components of GRBs
that extend at least up to 30 GeV, as it has been observed by Fermi LAT. The
two DAQ systems have an energy threshold that is low enough to observe events
similar to GRB 090510 and GRB 090902b with the characteristics observed by
Fermi LAT. HAWC will provide information about the high-energy spectra of GRBs
which in turn could help to understanding about e-pair attenuation in GRB jets,
extragalactic background light absorption, as well as establishing the highest
energy to which GRBs accelerate particles
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