Machining and grinding of ultrahigh-strength steels and stainless steel alloys

Machining and grinding of ultrahigh-strength steels and stainless steel alloy

Digital competence across boundaries - beyond a common Nordic model of the digitalisation of K-12 schools?

This paper explores policy related to digital competence and the digitalisation of Nordic K-12 schools. Anchored in some key transnational policies on digital competence, it describes some current Nordic movements in the national policies of Denmark, Finland, Norway and Sweden. The concept of boundary objects is used as an analytical lens, for understanding digital competence as a plastic and temporal concept that can be used to discuss the multi-dimensional translation of this concept in these Nordic countries. The paper ends with a discussion of the potential to view digital competence as a unifying boundary object that, with its plasticity, temporality and n-dimensionality, can show signs of common Nordic efforts in the K-12 school policy.Peer reviewe

The impact of emotional well-being on long-term recovery and survival in physical illness: a meta-analysis

This meta-analysis synthesized studies on emotional well-being as predictor of the prognosis of physical illness, while in addition evaluating the impact of putative moderators, namely constructs of well-being, health-related outcome, year of publication, follow-up time and methodological quality of the included studies. The search in reference lists and electronic databases (Medline and PsycInfo) identified 17 eligible studies examining the impact of general well-being, positive affect and life satisfaction on recovery and survival in physically ill patients. Meta-analytically combining these studies revealed a Likelihood Ratio of 1.14, indicating a small but significant effect. Higher levels of emotional well-being are beneficial for recovery and survival in physically ill patients. The findings show that emotional well-being predicts long-term prognosis of physical illness. This suggests that enhancement of emotional well-being may improve the prognosis of physical illness, which should be investigated by future research

Precision bond lengths for Rydberg Matter clusters KN (N = 19, 37, 61 and 91) in excitation levels n = 4 - 8 from rotational radio-frequency emission spectra

Clusters of the electronically excited condensed matter Rydberg Matter (RM) are planar and six-fold symmetric with magic numbers N = 7, 19, 37, 61 and 91. The bond distances in the clusters are known with a precision of +- 5% both from theory and Coulomb explosion experiments. Long series of up to 40 consecutive lines from rotational transitions in such clusters are now observed in emission in the radio-frequency range 7-90 MHz. The clusters are produced in five different vacuum chambers equipped with RM emitters. The most prominent series with B = 0.9292 +- 0.0001 MHz agrees accurately with expectation (within 2%) for the planar six-fold symmetric cluster K19 in excitation level n = 4. Other long series agree even better with K19 at n = 5 and 6. The ratio between the interatomic distance and the theoretical electron orbit radius (the dimensional ratio) for K19 in n = 4 is found to be 2.8470 +- 0.0003. For clusters K19 (n = 6) and K37 (n = 7 and 8) the dimensional ratio 2.90 is the highest value that is found, which happens to be exactly the theoretical value. Clusters K61 and K91 in n = 5 and 6 have slightly lower dimensional ratios. This is expected since the edge effects are smaller. Intensity alternations are observed of approximately 7:3. The nuclear spins interact strongly with the magnetic field from the orbiting electrons. Spin transitions are observed with energy differences corresponding accurately (within 0.6%) to transitions with apparent total (delta)F = -3 at excitation levels n = 5 and 6. The angular momentum coupling schemes in the clusters are complex but well understood.Comment: 37 pages, 14 figure

Total synthesis of the Amaryllidaceae alkaloid clivonine

Two syntheses of the Amaryllidaceae alkaloid clivonine (1) are described. Both employ previously reported 7-arylhydrindane 6 as an intermediate but differ in the method employed for subsequent introduction of what becomes the ring-B lactone carbonyl carbon (C7). The synthesis featuring a Bischler–Napieralski reaction for this transformation constitutes the first asymmetric synthesis of natural (+)-clivonine. Crystal structures for compounds (±)-13, (±)-16, (−)-20 and (±)-28 are also reported

Anti-Biofilm Compounds Derived from Marine Sponges

Bacterial biofilms are surface-attached communities of microorganisms that are protected by an extracellular matrix of biomolecules. In the biofilm state, bacteria are significantly more resistant to external assault, including attack by antibiotics. In their native environment, bacterial biofilms underpin costly biofouling that wreaks havoc on shipping, utilities, and offshore industry. Within a host environment, they are insensitive to antiseptics and basic host immune responses. It is estimated that up to 80% of all microbial infections are biofilm-based. Biofilm infections of indwelling medical devices are of particular concern, since once the device is colonized, infection is almost impossible to eliminate. Given the prominence of biofilms in infectious diseases, there is a notable effort towards developing small, synthetically available molecules that will modulate bacterial biofilm development and maintenance. Here, we highlight the development of small molecules that inhibit and/or disperse bacterial biofilms specifically through non-microbicidal mechanisms. Importantly, we discuss several sets of compounds derived from marine sponges that we are developing in our labs to address the persistent biofilm problem. We will discuss: discovery/synthesis of natural products and their analogues—including our marine sponge-derived compounds and initial adjuvant activity and toxicological screening of our novel anti-biofilm compounds

Milton\u27s Rival Hermeneutics: Reason is but Choosing

Recent critical conversation has described John Milton\u27s major works as sites of uncertainty, irreconcilability, or even confusion — as texts that actually reflect radical incoherence and openness. These newer critical voices posit, moreover, that traditional critics must strain to find coherence and authorial control in Milton\u27s poetry. Richard DuRocher and Margaret Thickstun, together with an esteemed group of Milton scholars from a wide range of critical and theoretical backgrounds, respond to this challenge. While accepting the presence of uncertainty and welcoming the multiple perspectives that Milton builds into his works, this volume offers a variety of nuanced approaches to Milton\u27s texts.https://digitalcommons.hamilton.edu/books/1010/thumbnail.jp

Same Behaviors, Different Outcomes: Mothers’ and Fathers’ Observed Challenging Behaviors Measured Using a New Coding System Relate Differentially to Children’s Social-Emotional Development

This study used a newly developed coding system for measuring the quality of parenting behavior to examine associations with children’s social-emotional development. The Risky Interaction Support and Challenge Scale (RISCS) measures the extent to which parents engage in behaviors that present physical and regulatory challenges to children, as well as parents’ tendency to allow children to pursue action goals autonomously. These behaviors were observed while parents (n = 57 fathers; n = 55 mothers; n = 50 pairs) interacted with their 1-year-olds who played on a structure that included a slide, a small climbing wall, and a tunnel. Trained raters reliably used the RISCS to measure several dimensions of parent behaviors related to children’s exploration, and all but one of the dimensions captured adequate variability in parent behavior. Although mothers and fathers did not differ in any of the dimensions, the associations between parent behavior and children’s social-emotional development did not overlap. Fathers who engaged in greater autonomy allowance and lower overprotection had toddlers with lower levels of internalizing behavior, whereas mothers who challenged children’s regulatory competence had toddlers with lower levels of externalizing behavior and greater competence. We discuss the implications of the findings for the literature on attachment theory and father-child relationships