Attention Deficit Hyperactivity Disorder: Is There an App for That? Suitability Assessment of Apps for Children and Young People With ADHD

Background: Attention-deficit/hyperactivity disorder (ADHD) is a complex highly comorbid disorder, which can have a huge impact on those with ADHD, their family, and the community around them. ADHD is currently managed using pharmacological and nonpharmacological interventions. However, with advances in technology and an increase in the use of mobile apps, managing ADHD can be augmented using apps specifically designed for this population. However, little is known regarding the suitability and usability of currently available apps. Objective: The aim of this study was to explore the suitability of the top 10 listed apps for children and young people with ADHD and clinicians who work with them. It is hypothesized that mobile apps designed for this population could be more suitably designed for this population. Methods: The top 10 listed apps that are specifically targeted toward children and young people with ADHD in the United Kingdom were identified via the Google Play (n=5) and iTunes store (n=5). Interviews were then undertaken with 5 clinicians who specialize in treating this population and 5 children and young people with ADHD themselves, to explore their opinions of the 10 apps identified and what they believe the key components are for apps to be suitable for this population. Results: Five themes emerged from clinician and young people interviews: the accessibility of the technology, the importance of relating to apps, addressing ADHD symptoms and related difficulties, age appropriateness, and app interaction. Three additional themes emerged from the clinician interviews alone: monitoring symptoms, side effects and app effect on relationships, and the impact of common comorbid conditions. The characteristics of the apps did not appear to match well with the views of our sample. Conclusions: These findings suggest that the apps may not be suitable in meeting the complex needs associated with this condition. Further research is required to explore the value of apps for children and young people with ADHD and their families and, in particular, any positive role for apps in the management of ADHD in this age group. A systematic review on how technology can be used to engage this population and how it can be used to help them would be a useful way forward. This could be the platform to begin exploring the use of apps further

Operational Research: Methods and Applications

Throughout its history, Operational Research has evolved to include a variety of methods, models and algorithms that have been applied to a diverse and wide range of contexts. This encyclopedic article consists of two main sections: methods and applications. The first aims to summarise the up-to-date knowledge and provide an overview of the state-of-the-art methods and key developments in the various subdomains of the field. The second offers a wide-ranging list of areas where Operational Research has been applied. The article is meant to be read in a nonlinear fashion. It should be used as a point of reference or first-port-of-call for a diverse pool of readers: academics, researchers, students, and practitioners. The entries within the methods and applications sections are presented in alphabetical order

Occupational Health & Safety (OHS) management practices in micro- and small-sized enterprises: The case of the Portuguese waste management sector

The waste management sector is dominated by micro and small-sized enterprises. Although it is possible to anticipate that they may face the same problems as other small firms, information about activities related to the prevention of occupational risks in this sector and how this influences Occupational Health & Safety (OHS) performance is still limited. This study aims to address the issue, contributing to current literature about the protection of employees and the prevention of occupational risks in the waste management sector. The study was conducted at 66 enterprises in Portugal. Data about OHS management practices was collected through different sources, such as questionnaires applied to employers and analysis of documents and records available at the enterprise. A summative index that assesses seven OHS performance aspects was used to characterize the enterprises regarding their OHS performance level. The results showed that micro and small-sized waste management firms display several constraints with regard to OHS management. Several enterprises still do not have organized preventive services. Additionally, OSH policies or objectives, risk assessment, training and accident recording mechanisms were found to be non-existent in several cases. The time dedicated by employers to OHS issues and the support of external advisory services was also low for some firms. A positive and statistically significant association was found between these variables and the enterprises’ OHS performance level. Future research will focus on designing an intervention to improve OHS in the waste management sector as a whole

Analysis of Radial Dependence of the Localized Magnetic Field using Artificial Neural Networks

The measurements of the angular distributions of charged particles have a long history in atomic and molecular collision studies. To detect all electrons originating from collision has great importance in experimental studies. Due to the physical constraints of the experimental instruments, electrons in definite angles can be detected. Magnetic angle changer is designed to steer electrons scattered at undetectable angles. The magnetic angle changer is a source of the localized magnetic field. A well-controlled magnetic field in the interaction region changes the angles of the electron trajectories. In this study, artificial neural networks have been performed to obtain variation of the magnetic field strength as a function of radial distance calculated from boundary element method. A stringent quality filter is used for data to produce more robust artificial neural network based prediction. The results indicate that the well-trained artificial neural networks can predict the effect on the radial dependence of the localized magnetic field with tremendous precision. It is believed that this study will introduce a new insight into collision studies

Pentraxin-3 Levels in Beta Thalassemia Major and Minor Patients and Its Relationship With Antioxidant Capacity and Total Oxidant Stress.

Thalassemia major (TM) results in hemolytic anemia, an increase in intestinal iron absorption, and occurrence of iron loading due to erythrocyte transfusion; the disease is characterized by oxidative damage in major organs. Oxidative stress leads to vascular endothelial damage and forms the basis for serious cardiovascular diseases. Pentraxin-3 (PTX-3) is one of the markers of vascular endothelial damage that increases in response to the oxidative stress, which can be used as an early diagnostic marker for inflammation. This study's purpose is to define the relation between PTX-3 and the vascular endothelial damage that increases with oxidative stress in thalassemia patients. Our study included 35 TM patients, 30 β-thalassemia minor patients, and 30 healthy children. As a result of our study, in TM patients, a positive relation was detected between the PTX-3 levels and the total oxidative stress, triglyceride, and very low-density lipoprotein values, whereas a negative relation was detected with the total antioxidant capacity and high-density lipoprotein values. This result shows that as oxidant stress increases, PTX-3 levels also increase; very low-density lipoprotein and triglyceride contribute to the endothelial damage occurring with oxidative stress. As a result, it was concluded that vascular endothelial damage in thalassemia patients can be evaluated through the serum PTX-3 level

5-Allyl-3-Methoxy-2-(P-Tolylsulfonyloxy)-Azobenzene

The structure of the title compound, 5-allyl-3-methoxy-2-(p-tolylsulfonyloxy)diphenyldiazene, C23H22N2O4S, shows the characteristic features of azobenzene derivatives. The rings in the azobenzene frame are twisted by 16.97(2) and 5.37(2)degrees out of the azo group plane. The larger twist is associated with the 5-allyl-3-methoxy ring. The azobenzene moiety of the molecule has a trans configuration.WoSScopu

Omega-3 prevents myelin degeneration in rat foetuses exposed to radiation

The aim of this study is to investigate the protective effect of antioxidant omega-3 fatty acid (FA) on demyelinisation and degeneration of nerves in central and peripheral nervous systems (CNS and PNS) of rat foetuses. 38 pregnant rats weighing 140–155 g were used. Rats were divided into five groups. Group 1: 7 rats exposed to radiation treatment (RT) for 1 hour/day only; Group 2: 7 rats exposed to RT + Omega-3 FA (p.o.) for 1 hour/day; Group 3: 7 rats exposed to RT for 4 hours/day; Group 4: 7 rats exposed to RT + Omega-3 FA (p.o.) for 4 hours/day; and Group 5: 10 rats with no treatment. Nerve injury was induced by whole-body exposure to 20-µT magnetic field. Omega-3 FA was given orally at a dose of 50 mg/kg. After 18 days, foetuses were delivered by the milking method; CNS and PNS were taken out for pathological examination. The degeneration scores of Group 2 were significantly lower than those of Group 1, whereas the degeneration scores of Group 4 were significantly higher than those of Groups 1 and 3. In conclusion, radiation increases demyelinisation and degeneration of nerves in the rat foetuses’ CNS and PNS. Omega-3 FA prevents myelin and nerve degeneration in rat foetuses in low-dose radiation exposure. © 2015 Informa UK Limited, trading as Taylor & Francis Group

Covarian mappings and coupled fixed point results in bipolar metric spaces

In this paper, we establish the existence and uniqueness of common coupled fixed point results for three covariant mappings in bipolar metric spaces. Moreover, we give an illustration which presents the applicability of the achieved results also we provided applications to homotopy theory as well as integral equations