Сутність адміністративного права за новою класифікацією юриспруденції

На основі новітніх підходів до розумінні завдань, об’єктів і класифікації юридичних наук запропонована перспектива розвитку адміністративного права і процесу, які повинні трансформуватися в нові юридичні науки: базисноантиделыктне «Адміністра­тивне право України», процедурне «Админо­регламентное право України» та у низку регулятивних юридичних наук, а також розробити Адміністративний кодекс України, Адміно-регламентній кодекс України, відповідні регулятивні кодекси.На основе новейших подходов к понимании задач, объектов и классификации юридических наук предложена перспектива развития административного права и процес­са, которые должны трансформироваться в новые юридические науки: базисноанти­деликтное «Административное право Украины», процедурное «Админо­регламентное право Украины» и ряд регулятивных юридических наук, а также разработать Административный кодекс Украины, Админо-регламентный кодекс Украины, соответствую­щие регулятивные кодексы.On the basis of the newest fittings to for understanding of tasks, objects and classification of legal sciences the prospect of development of administrative law and process is offered, which must be transformed in new legal sciences: basisuntidelictical the «Administrative law of Ukraine», procedural «Administrative-reglamental law of Ukraine» and the row of regulative legal sciences, and also to develop the Administrative code of Ukraine, Administrative­-reglamental code of Ukraine, proper regulative codes

Некоторые подходы к совершенствованию регионально-институциональной основы курортно-гостиничных услуг в Автономной республике Крым

Рассмотрены подходы (институциональный, региональный, проблемно-ориентированный и маркетинговый) к разработке регионально-институциональной модели курортно-гостиничного хозяйства как одной из важнейших составляющих институциональной модели курортно-рекреационного комплекса Автономной Республики Крым.Розглядаються підходи (інституційний, регіональний, проблемно-орієнтований і маркетинговий) до розробки регіонально-інституційної моделі курортно-готельного господарства як однієї з найважливіших складових інституційної моделі курортно-рекреаційного комплексу Автономної Республіки Крим

A perspective on the developmental toxicity of inhaled nanoparticles.

This paper aimed to clarify whether maternal inhalation of engineered nanoparticles (NP) may constitute a hazard to pregnancy and fetal development, primarily based on experimental animal studies of NP and air pollution particles. Overall, it is plausible that NP may translocate from the respiratory tract to the placenta and fetus, but also that adverse effects may occur secondarily to maternal inflammatory responses. The limited database describes several organ systems in the offspring to be potentially sensitive to maternal inhalation of particles, but large uncertainties exist about the implications for embryo–fetal development and health later in life. Clearly, the potential for hazard remains to be characterized. Considering the increased production and application of nanomaterials and related consumer products a testing strategy for NP should be established. Due to large gaps in data, significant amounts of groundwork are warranted for a testing strategy to be established on a sound scientific basis

The MOBI-Kids Study Protocol: Challenges in Assessing Childhood and Adolescent Exposure to Electromagnetic Fields from Wireless Telecommunication Technologies and Possible Association with Brain Tumor Risk

The rapid increase in mobile phone use in young people has generated concern about possible health effects of exposure to radiofrequency (RF) and extremely low frequency (ELF) electromagnetic fields (EMF). MOBI-Kids, a multinational case-control study, investigates the potential effects of childhood and adolescent exposure to EMF from mobile communications technologies on brain tumor risk in 14 countries. The study, which aims to include approximately 1,000 brain tumor cases aged 10-24 years and two individually matched controls for each case, follows a common protocol and builds upon the methodological experience of the INTERPHONE study. The design and conduct of a study on EMF exposure and brain tumor risk in young people in a large number of countries is complex and poses methodological challenges. This manuscript discusses the design of MOBI-Kids and describes the challenges and approaches chosen to address them, including: (1) the choice of controls operated for suspected appendicitis, to reduce potential selection bias related to low response rates among population controls; (2) investigating a young study population spanning a relatively wide age range; (3) conducting a large, multinational epidemiological study, while adhering to increasingly stricter ethics requirements; (4) investigating a rare and potentially fatal disease; and (5) assessing exposure to EMF from communication technologies. Our experience in thus far developing and implementing the study protocol indicates that MOBI-Kids is feasible and will generate results that will contribute to the understanding of potential brain tumor risks associated with use of mobile phones and other wireless communications technologies among young people

Влияние лечения тиотриазолином на состояние перекисного окисления липидов и уровни иммуновоспалительных и вазоактивных эндотелиальных факторов у больных с хронической сердечной недостаточностью и helicobacter pylori-негативными гастропатиями

Показано, что включение в схему патогенетического лечения больных с ХСН, hp-негативной гастропатией и умеренным или высоким риском сердечно-сосудистых осложнений (ССО) антиоксиданта тиотриазолина сопровождается достоверно более выраженными позитивными эффектами на процессы перекисного окисления липидов и содержание в крови иммуновоспалительных и вазоактивных эндотелиальных факторов по сравнению с динамикой при лечении без использования тиотриазолина, причем степень положительной динамики у больных с высоким риском ССО достоверно больше.Показано, що включення у схему патогенетичного лікування хворих із ХСН, hр-негативною гастропатією і з помірним або високим ризиком серцево-судинних ускладнень (ССУ) антиоксиданта тіотриазоліна супроводжується достовірно більш вираженими позитивними ефектами на процеси перекисного окислення ліпідів та вміст у крові імунозапальних і вазоактивних ендотеліальних факторів порівняно з динамікою при лікуванні без використання тіотриазоліну, причому ступінь позитивної динаміки у хворих із високим ризиком ССУ достовірно більший.It is shown that the use of tiotriazolin in the scheme of pathogenetic treatment of patients with chronic heart failure, Hp-negative gastropathy, and moderate or high risk of cardiovascular complications (CVC) is accompanied by significantly higher positive effect on the processes of lipid peroxidation and the amount of immune inflammation and vasoactive endothelial factors in the blood when compared with the dynamics at treatment without the use of tiotriazolin, the degree of positive dynamics in patients with a high risk of CVC being significantly higher

Comorbidity of eczema, rhinitis, and asthma in IgE-sensitised and non-IgE-sensitised children in MeDALL: a population-based cohort study

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Long-term exposure to elemental constituents of particulate matter and cardiovascular mortality in 19 European cohorts: Results from the ESCAPE and TRANSPHORM projects

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Willingness to pay to avoid health risks from road-traffic-related air pollution and noise across five countries

We conducted a multi-country study to estimate the perceived economic values of traffic-related air pollution and noise health risks within the framework of a large European project. We used contingent valuation as a method to assess the willingness-to-pay (WTP) for both types of pollutants simultaneously. We asked respondents how much they would be willing to pay annually to avoid certain health risks from specific pollutants. Three sets of vignettes with different levels of information were provided prior to the WTP questions. These vignettes described qualitative general health risks, a quantitative single health risk related to a pollutant, and a quantitative scenario of combined health risks related to a pollutant. The mean WTP estimates to avoid road-traffic air pollution effects for the three vignettes were: €130 per person per year (pp/y) for general health risks, €80. pp/y for a half year shorter in life expectancy, and €330. pp/y to a 50% decrease in road-traffic air pollution. Their medians were €40. pp/y, €10. pp/y and €50. pp/y, respectively. The mean WTP estimates to avoid road-traffic noise effects for the three vignettes were: €90. pp/y for general health risks, €100. pp/y for a 13% increase in severe annoyance, and €320. pp/y for a combined-risk scenario related to an increase of a noise level from 50. dB to 65. dB. Their medians were €20. pp/y, €20. pp/y and €50. pp/y, respectively. Risk perceptions and attitudes as well as environmental and pollutant concerns significantly affected WTP estimates. The observed differences in crude WTP estimates between countries changed considerably when perception-related variables were included in the WTP regression models. For this reason, great care should be taken when performing benefit transfer from studies in one country to another

Daily changes of peak expiratory flow and respiratory symptom occurrence around a soy processing factory

Objectives. To evaluate sensitization and acute respiratory health effects in inhabitants living in the vicinity of a factory producing soy oil. Methods. Two panels of potential responders were created on the basis of a response to a short screening questionnaire sent to random samples of 1,000 exposed and 1,000 non-exposed individuals living around the factory and a control area. Individuals responding to the questionnaire were invited for a medical evaluation, including a respiratory symptom questionnaire and skin prick testing, for a panel of common allergens and a soy allergen extract. This resulted in 53 atopic and/or asthmatic inhabitants from the area surrounding the factory and 30 comparable control subjects. In these subjects, morning and evening Peak Expiratory Flow (PEF), respiratory symptoms and medication use were recorded daily during a 10-week period in the autumn. At the same time, soy allergen and endotoxin concentrations were determined in airborne dust in the exposed and the control area. The wind direction relative to the location of a subjects' house and the factory was used to determine whether an individual was exposed on a particular day. Results. Only few of the atopic subjects were sensitized to soy. PEF showed a decrease, respiratory symptoms and bronchodilator use, an increase among soy sensitized subjects after having been downwind from the factory. Airborne soy allergen was found more frequently in the area surrounding the factory and levels were higher than in the control area. Highest levels were found on the factory premises. Only a weak association was found with wind direction. Airborne endotoxin concentrations did not show a consistent pattern with distance, but levels were clearly higher on the factory premises. Conclusion. Sensitization to soy allergen was not increased among the population sample living in the vicinity of the factory. Soy sensitized individuals living in the surroundings of the factory reported more respiratory symptoms, used bronchodilators more often and had a lower PEF after having been downwind of the factory