A comparison of bird communities in loblolly vs. white pine plantations on the Oak Ridge National Environmental Research Park

The value of pine plantations as habitat for avian communities has not been extensively studied. Bird communities that occur in pine plantations need to be chronicled and managed to sustain their diversity. The objectives of this study were to 1) characterize breeding and winter bird communities in loblolly and white pine plantations on the U.S. Department of Energy\u27s Oak Ridge Reservation, and 2) assess and compare bird density, species richness, species diversity, and species equitability of the two habitats. Both loblolly and white pine exhibited well-developed hardwood understories, and supported diverse bird communities. However, the breeding bird density in loblolly pine was higher than in white pine in 1988; loblolly pine had a higher breeding bird density and species richness than white pine in 1989. The understory nesting birds in loblolly were characterized by a number of bird species associated with edge habitat that were not found in white pine; cavity and overstory nesting birds had similar densities in both pine types. The predominance of edge species in loblolly pine may have accounted for the higher bird density and species richness exhibited by this pine type. Certain structural characteristics, such as the more open overstory and dense ground cover of loblolly, may have created habitat attractive to edge bird species. Both pine types were occupied by species normally associated with the interior of deciduous forests. The small sizes of the pine stands and the close proximity to larger tracts of deciduous forests may have allowed the stands to be utilized as part of several species\u27 territories. Three species listed as either threatened or in need of management by the State of Tennessee were observed exclusively in white pine stands. This highlighted the importance of considering the particular species attracted to a habitat, along with other community values. Winter bird communities in loblolly and white pine did not differ significantly. Large flocks of mixed and/or single species of birds utilized the overstory and understory of both pine types, and also utilized adjacent habitats. Birds apparently selected structure that provided appropriate food and shelter regardless of forest type

The genetic architecture of the human cerebral cortex

The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Pornography, women and feminism: between pleasure and politics

This article draws on a qualitative research study which set out to explore women’s experiences and views of pornography within the broader context of conflicting feminist positions on pornography. The research methodology posed an implicit criticism of the kind of ‘findings’ familiar from mainstream psychological research: semi-structured interviews were conducted with women from diverse backgrounds in the UK, and feminist theory and discourse analysis were used to inform interpretation of their accounts. Although the question of feminism was not explicitly raised by the interviewer, it emerged as a recurrent theme in interviews, with interviewees suggesting that the feminist anti-porn stance in particular has influenced their perspective on pornography. Their accounts show that women’s experiences are variegated, individual and complex, and that discourses of pornography and feminism may be negotiated in unpredictable ways

“The Gender and Geography of Citizenship in Mexico-U.S. Transnational Spaces”

This paper proposes an approach for analyzing the gender and geography of citizenship practices in transnational social spaces in order to contribute to theorizing on state-transmigrant relations and citizenship. Drawing on feminist scholarship on citizenship I conceptualize citizenship as including formal rights and substantive citizenship practices that are exercised in relation to different levels of political authority, and in different geographic sites within transnational spaces. The approach is used to examine dynamics between Mexican state policies and programs and transmigrant organizations in Los Angeles. Using data from research on migration between Zacatecas and California, I argue that men find a privileged arena of action in transmigrant organizations and Mexican state-mediated transnational social spaces, which become spaces for practicing forms of citizenship that enhance their social and gender status. Women are excluded from active citizenship in this arena, but often practice substantive social citizenship in the United States