49 research outputs found
Sensing Movement: Microsensors for Body Motion Measurement
Recognition of body posture and motion is an important physiological function that can keep the body in balance. Man-made motion sensors have also been widely applied for a broad array of biomedical applications including diagnosis of balance disorders and evaluation of energy expenditure. This paper reviews the state-of-the-art sensing components utilized for body motion measurement. The anatomy and working principles of a natural body motion sensor, the human vestibular system, are first described. Various man-made inertial sensors are then elaborated based on their distinctive sensing mechanisms. In particular, both the conventional solid-state motion sensors and the emerging non solid-state motion sensors are depicted. With their lower cost and increased intelligence, man-made motion sensors are expected to play an increasingly important role in biomedical systems for basic research as well as clinical diagnostics
IMECE2008-67855 STUDY OF WHOLE BLOOD VISCOSITY USING A MICROFLUIDIC DEVICE
ABSTRACT Cardiovascular diseases include a wide range of disorders that affect heart and blood vessels, and are the leading cause of death in the Unite
IMECE2008-67924 BIOMECHANICAL DEVICE TOWARDS QUANTITATIVE MASSAGE
ABSTRACT Massage therapies are widely employed for improving and recovering tissue functions and physical activities. It i
Noninvasive electromyometrial imaging of human uterine maturation during term labor
Electromyometrial imaging (EMMI) was recently developed to image the three-dimensional (3D) uterine electrical activation during contractions noninvasively and accurately in sheep. Herein we describe the development and application of a human EMMI system to image and evaluate 3D uterine electrical activation patterns at high spatial and temporal resolution during human term labor. We demonstrate the successful integration of the human EMMI system during subjects\u27 clinical visits to generate noninvasively the uterine surface electrical potential maps, electrograms, and activation sequence through an inverse solution using up to 192 electrodes distributed around the abdomen surface. Quantitative indices, including the uterine activation curve, are developed and defined to characterize uterine surface contraction patterns. We thus show that the human EMMI system can provide detailed 3D images and quantification of uterine contractions as well as novel insights into the role of human uterine maturation during labor progression
New genetic loci link adipose and insulin biology to body fat distribution.
Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms
Elucidating the underlying physics in a two-terminal all-perovskite tandem solar cell: A guideline towards 30% power conversion efficiency
10.1016/j.solener.2021.11.029Solar Energy231716-73
A mixed-integer optimization for bifacial two-terminal perovskite-on-perovskite tandem solar cells
10.1016/j.solener.2023.111905Solar Energy262111905-11190
Optoelectronic modeling and sensitivity analysis of a four-terminal all-perovskite tandem solar cell – Identifying pathways to improve efficiency
10.1016/j.solener.2021.01.021Solar Energy216589-60
Optimizing bifacial all-perovskite tandem solar cell: How to balance light absorption and recombination
10.1016/j.solener.2021.12.040Solar Energy2311092-110