26 research outputs found
Meeting report: a workshop on Best Practices in Genome Annotation
Efforts to annotate the genomes of a wide variety of model organisms are currently carried out by sequencing centers, model organism databases and academic/institutional laboratories around the world. Different annotation methods and tools have been developed over time to meet the needs of biologists faced with the task of annotating biological data. While standardized methods are essential for consistent curation within each annotation group, methods and tools can differ between groups, especially when the groups are curating different organisms. Biocurators from several institutes met at the Third International Biocuration Conference in Berlin, Germany, April 2009 and hosted the ‘Best Practices in Genome Annotation: Inference from Evidence’ workshop to share their strategies, pipelines, standards and tools. This article documents the material presented in the workshop
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The Gene Ontology in 2010: extensions and refinements
The Gene Ontology (GO) Consortium (http://www.geneontology.org) (GOC) continues to develop,
maintain and use a set of structured, controlled
vocabularies for the annotation of genes, gene
products and sequences. The GO ontologies
are expanding both in content and in structure.
Several new relationship types have been introduced
and used, along with existing relationships,
to create links between and within the GO domains.
These improve the representation of biology,
facilitate querying, and allow GO developers to systematically
check for and correct inconsistencies
within the GO. Gene product annotation using GO
continues to increase both in the number of total
annotations and in species coverage. GO tools,
such as OBO-Edit, an ontology-editing tool, and
AmiGO, the GOC ontology browser, have seen
major improvements in functionality, speed and
ease of use.This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by Oxford University Press. The published article can be found at: http://nar.oxfordjournals.org/