26 research outputs found
System integration of hydrogen energy technologies using renewable energy resources
- Author
- Publication venue
- Scholars\u27 Mine
- Publication date
- 01/01/2015
- Field of study
The objective of this work has two major tasks that investigation the use of CHHP system at the Missouri University of Science and Technology (Missouri S&T) campus and studying solid waste as renewable source of energy: current and future possibility in Libya. Task one has three major topics. In Topic I, Design of Combined Hydrogen, Heat and Power (CHHP) system for the campus using local resources and treated biogas can be used to generate CHHP using a Molten Carbonate Fuel Cell (MCFC). In Topic II, hydrogen recovery and cleaning system, Heat recovery and electric power usage, hydrogen compression, storage, and dispensing/distribution system, electricity use and economic benefits of the system in operation, and thermal use. In Topic III, utilization of hydrogen production, hydrogen end-uses, CHHP hydrogen output, and hydrogen application consider but not used in the design. In task 2, generation of solid waste in Libya, overview of Waste-to-energy (WTE) conversions, solid waste management, WTE benefits and challenges in Libya. Results for Tasks I and II have been presented. --Abstract, page iv
Malignant gastrointestinal neuroectodermal tumor: a case report and review of the literature
- Author
- Ahmed Alsayyah
- CE Comin
- CR Antonescu
- DL Stockman
- E Zambrano
- FE D’Amico
- G Venkataraman
- J Kong
- J Wang
- JC Yang
- JM Boland
- JP Lagmay
- Jumana A. Alratroot
- K Lasithiotakis
- K Thway
- L Insabato
- M Hisaoka
- M Joo
- Mohamed A. Shawarby
- Mohammad A. Al hamad
- Mohammed J. Alyousef
- N Friedrichs
- P Pauwels
- P Shenjere
- Tarek ElSharkawy
- Tarek M. Hashem
- W Huang
- WL Wang
- Z Zhao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Global economic burden of unmet surgical need for appendicitis
- Author
- Aahlin E. K.
- Aamer A.
- Aaniana K.
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- Abantanga F.
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- Abbouch M.
- Abd-Elmawla M.
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- Abdallah E.
- Abdel-Aty A.
- Abdel-Hameed N.
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- Publication venue
- Oxford University Press
- Publication date
- 01/01/2022
- Field of study
Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
Laparoscopy in management of appendicitis in high-, middle-, and low-income countries: a multicenter, prospective, cohort study.
- Author
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- Abbas M
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- Zapata Ponze De Leon M
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- Zerihun AB
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: Appendicitis is the most common abdominal surgical emergency worldwide. Differences between high- and low-income settings in the availability of laparoscopic appendectomy, alternative management choices, and outcomes are poorly described. The aim was to identify variation in surgical management and outcomes of appendicitis within low-, middle-, and high-Human Development Index (HDI) countries worldwide. METHODS: This is a multicenter, international prospective cohort study. Consecutive sampling of patients undergoing emergency appendectomy over 6 months was conducted. Follow-up lasted 30 days. RESULTS: 4546 patients from 52 countries underwent appendectomy (2499 high-, 1540 middle-, and 507 low-HDI groups). Surgical site infection (SSI) rates were higher in low-HDI (OR 2.57, 95% CI 1.33-4.99, p = 0.005) but not middle-HDI countries (OR 1.38, 95% CI 0.76-2.52, p = 0.291), compared with high-HDI countries after adjustment. A laparoscopic approach was common in high-HDI countries (1693/2499, 67.7%), but infrequent in low-HDI (41/507, 8.1%) and middle-HDI (132/1540, 8.6%) groups. After accounting for case-mix, laparoscopy was still associated with fewer overall complications (OR 0.55, 95% CI 0.42-0.71, p < 0.001) and SSIs (OR 0.22, 95% CI 0.14-0.33, p < 0.001). In propensity-score matched groups within low-/middle-HDI countries, laparoscopy was still associated with fewer overall complications (OR 0.23 95% CI 0.11-0.44) and SSI (OR 0.21 95% CI 0.09-0.45). CONCLUSION: A laparoscopic approach is associated with better outcomes and availability appears to differ by country HDI. Despite the profound clinical, operational, and financial barriers to its widespread introduction, laparoscopy could significantly improve outcomes for patients in low-resource environments. TRIAL REGISTRATION: NCT02179112
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf AM
- Abdelrouf DM
- Abdelshafy M
- Abdelshakour M
- Abdrabou AK
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
- Abdulbagi O
- Abdulgawad M
- Abdulhakeem EM
- Abdullah AAN
- Abdullah MA
- Abdullah N
- Abdullah NAN
- Abdullah NAN
- Abdullahi L
- Abdurrazzaaq A
- Abebe NS
- Abebe NS
- Abem OE
- Aber A
- Abington E
- Abiola O
- Aboarab A
- Aboelella M
- Aboelmagd O
- Aboelsoud MR
- Aboraya M
- Aboraya M
- Abouelnasr A
- Aboul-Naga MS
- Abouzahra A
- Abouzaid A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abu Qumbos A
- Abu-toyour M
- Abubakr M
- Abudeeb H
- Abuowda Y
- Abuqwaider E
- Abusalem L
- Abuseif M
- Abushamleh S
- Acharya P
- Ackom E
- Acquah E
- Adam A
- Adam N
- Adams R
- Adamu A
- Adawi I
- Adawi M
- Adebanjo A
- Adebanjo A
- Adebola O
- Adedeji A
- Adekoya A
- Adel A
- Adel A
- Adel BE
- Adel I
- Adella FJ
- Adelshone A
- Ademuyiwa A
- Ademuyiwa A
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Adenekan B
- Adeniran J
- Adeniran J
- Adeniyi A
- Adeniyi A
- Adesanya O
- Adesanya O
- Adesina A
- Adesina A
- Adesuyi A
- Adeyeye A
- Adeyeye A
- Adeyeye A
- Adham W
- Adhitama N
- Adil M
- Adisa AO
- Adisa AO
- Adu-Aryee N
- Afana S
- Afandy A
- Afifi AM
- Afzal M
- Agalianos C
- Agalianos C
- Agarwal A
- Agarwal A
- Agarwal A
- Agbedinu K
- Agius M
- Aglan A
- Aguado Suarez N
- Aguilar-Jimenez J
- Aguilera M
- Aguilera ML
- Aguilera ML
- Aguilera ML
- Aguilera O
- Aguilera-Arevalo M-L
- Ahlonsou G
- Ahlqvist S
- Ahlqvist S
- Ahlqvist S
- Ahmed A
- Ahmed A
- Ahmed A
- Ahmed EA
- Ahmed H
- Ahmed H
- Ahmed H
- Ahmed LAM
- Ahmed S
- Ahmed S
- Ahmed SM
- Ahounou EYS
- Aigrain Y
- Aiyaman C
- Ajah J
- Ajai O
- Ajao A
- Ajao AE
- Ajiboye A
- Akatibo E
- Akeel N
- Akhtar M
- Akoto E
- Akpenyi O
- Al Amin S
- Al Attar SM
- Al Awwad S
- Al Barrawi FE
- Al Bastawis F
- Al Meligy A
- Al Rafati AAR
- Al Raouf EA
- Al Saied G
- Al Subaie N
- Al-Aarag AA-R
- Al-Azraqi IAA
- Al-Bahrani A
- Al-Buhaisi A
- Al-Dakka E
- Al-Faifi JJ
- Al-faqawi M
- Al-farram H
- Al-Hameedi HII
- Al-Hasani RKMJ
- Al-khatib A
- Al-Mallah A
- Al-Marakby D
- Al-Mousa M
- Al-Nahrawi S
- Al-Obaedi O
- Al-saqqa S
- Al-Saqqa SW
- Al-Saqqa SW
- Al-shammari A
- Al-Slaibi I
- Al-taher T
- Alaael-Dein S
- Alada M
- Alahmady O
- Alakaloko F
- Alakaloko F
- Alaloul E
- Alamin S
- Alamoudi M
- Alamoudi U
- Albeladi B
- Albiety A
- Alcca Ticona W
- Aldalaq A
- Aldhafeeri S
- Aledrisy M
- Alejos Bermudez YE
- Alexander P
- Alexander P
- Alexander P
- Alexandre C
- Alfarsi MA
- Alghamdi A
- Alghamdi B
- Alghamdi M
- Alghamdi MSA
- Algohary O
- Alhabli I
- Alhady K
- Alhammali T
- Alhassan B
- Alhazmi W
- Alhendy M
- Alherz M
- Ali A
- Ali A
- Ali A
- Ali CDM
- Ali E
- Ali FM
- Ali H
- Ali S
- Ali SAWEW
- Ali SS
- Ali THA
- Ali W
- Alihonou T
- Alimi Q
- Alis H
- Aliyu H
- Aliyu M
- Aliyu S
- Aljboor K
- Aljiffry M
- Aljiffry M
- Aljohani E
- Aljohani E
- Aljohani S
- Alkaaki A
- Alkammash A
- Alkelani M
- Alkhabbaz D
- Alkhouri M
- Allam M
- Allam M
- Allam Y
- Allegri A
- Allegri A
- Allen JLY
- Allott R
- Almallah A
- Almoflihi A
- Almuallem S
- Almy J
- Alnaby MH
- Alnawam E
- Alnuqaydan SA
- Alnusairat A
- Alomar IN
- Alqahtani E
- Alqahtani S
- Alrahawy M
- Alrajraji M
- Alrifaie A
- AlRowais M
- Alsaggaf M
- Alsaggaf MU
- Alsaggaf MU
- Alser OH
- Alshareef R
- Altaf A
- Altaf A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamini A
- Altarayra M
- Althwainy A
- Altibi A
- Altinel Y
- Altinel Y
- Altoe F
- Altwigry AM
- Altwijri A
- Alvarado Jaramillo R
- Alvarez Barreda LM
- Alvi AR
- Alwafai MG
- Aly AK
- Aly MYM
- Alyacoubi S
- Alyahya R
- Alyami R
- Alyami R
- AlYoussef I
- Alzahrani A
- Alzahrani M
- Alzahrani M
- Alzayat T
- Aman NF
- Amandito R
- Amandito R
- Amandito R
- Amandito R
- Ambrona-Zafra D
- Ambrozeviciute V
- Ameen M
- Amer MA
- Amin HAA
- Amin J
- Amin J
- Amjad M
- Ammar M
- Ammar MS
- Amoah M
- Amoako J
- Amoako PT
- Amoako-Boateng M
- Amole I
- Amreia M
- Amreia M
- Anandkumar D
- Anderson D
- Anderson F
- Anderson R
- Anderson-Knight H
- Andersson L
- Andika FFA
- Andreotti D
- Andres Garcia-Marin J
- Andress C
- Andriola V
- Ang YL
- Angelieri D
- Anis E
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Antar S
- Antezana D
- Anthoulakis C
- Anthoulakis C
- Antoniozzi A
- Anwar AW
- Anwar N
- Anwer W
- Anyanwu L-J
- Anyanwu L-J
- Aonzo P
- Appeadu-Mensah W
- Appiah EK
- Aql S
- Aquilino F
- Arachchi PP
- Arachchige LAJJ
- Arafa O
- Arafa S
- Arango MCM
- Arango MCM
- Aranzabal Durand SY
- Araujo R
- Arcudi C
- Ardley R
- Arenas A
- Arevalo Azmitia JR
- Arias Pacheco RD
- Arman S
- Arman S
- Armando ChunguiBravo J
- Armellini A
- Arnaud A
- Arnaud AP
- Arnaud AP
- Arnaud AP
- Arroyo Basto CA
- Arshad MM
- Arslan E
- Arsyad HM
- Arthur T
- Arulampalam T
- Aruldas N
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- Asar YH
- Asare-Bediako K
- Asele FA
- Ashour A
- Ashour A
- Ashour K
- Ashraf SF
- Ashtari M
- Ashton A
- Asi F
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- Assal A
- Assouto PA
- Asturia S
- Asumah H
- Ata A
- Ata AAA
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- Atiyeh A
- Atkins ET
- Atkinson K
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- Attallah NA
- Attard M
- Attia A
- Attia AM
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- Aung KP
- Austraite A
- Aviles S
- Avoka A
- Awad I
- Awad SA
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo OO
- Aydin MC
- Ayyar S
- Aziz DNA
- Aziz MRA
- Aziz NA
- Azizeldine MG
- Azmitia Mendizabal CA
- Azodo IA
- Azzie G
- Azzie G
- Azzis O
- Baba S
- Bachri H
- Badawy M
- Badenjki MA
- Badicel M
- Badr A
- Badr MFM
- Badwi NM
- Badwi NM
- Badwy A
- Bahar S
- Baheeg M
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- Baillie K
- Baillie K
- Baird A
- Bakhaidar M
- Baki BE
- Bakr A
- Bakry HM
- Bala M
- Balalis D
- Baldacchino M
- Balducci G
- Balila RMH
- Balkan AZA
- Ballouhey Q
- Balmaceda R
- Balmaceda R
- Balmaceda R
- Balogun F
- Baltrunas R
- Baluch F
- Bamford R
- Bamicha A
- Bamicha A
- Banaitis VJ
- Bandi A
- Bandoh D
- Bani-Sadar A
- Banipal GS
- Baraka H
- Barakat SAE
- Barendegere V
- Barker T
- Barkolias C
- Barmayehvar B
- Barnabas GN
- Barnacle J
- Barneo L
- Barrionuevo Ojeda RR
- Barrios E
- Barrios E
- Barros De Castro Segundo LC
- Barroso de Lima CV
- Barry J
- Basilico S
- Basir ERM
- Bassem M
- Bassit KA
- Basso SMM
- Basson S
- Batt J
- Bayram S
- Beamon M
- Beasley W
- Beaton C
- Bedada AG
- Bediako-Bowan A
- Behar N
- Beisa V
- Beisa V
- Bekhet AH
- Bekhet NM
- Beleno AEM
- Belkouchi A
- Belli A
- Bello B
- Benammi S
- Benevento A
- Benevento A
- Benger M
- Bennai RM
- Benons N
- Bentounsi Z
- Benyaiche C
- Berti S
- Bertuello I
- Beuran M
- Beuran M
- Beyene R
- Bezerra Morais PA
- Bezzina M
- Bhang A
- Bhangu A
- Bhangu A
- Bhargava A
- Bharj IS
- Bhat S
- Bhatnagar A
- Bhattacharya S
- Bhopal KF
- Bhopal KF
- Bianco F
- Bigaran A
- Billy M
- Bin Adnan A
- Bin Hasnan M
- Bin Ismail MJ
- Bin Mahamood A
- Birindelli A
- Birring A
- Bisset C
- Bjorklund I
- Bjorklund I
- Blacker S
- Blackwell J
- Blanco R
- Blanco-Colino R
- Blencowe N
- Blencowe N
- Bliksoen M
- Blower E
- Bluelle R
- Blundell R
- Boakye-Yiadom K
- Boal M
- Bocchetti T
- Boddy A
- Bode C
- Bode C
- Bodur S
- Boereboom C
- Boggon A
- Boijsen M
- Bokhari S
- Bonavia K
- Bonavina L
- Bonavina L
- Bond-Smith G
- Bondin J
- Bondurri A
- Bondurri A
- Boni S
- Bonnard A
- Bonney W
- Borda Luque G
- Borda-Luque G
- Borda-Luque G
- Borg E
- Borg E
- Borg E
- Borin E
- Bortolasi L
- Bortolasi L
- Boshnaq M
- Botes S
- Bottini C
- Botto N
- Bouali O
- Bougard H
- Boukhal K
- Bowabsak A
- Bowe R
- Bowley D
- Bowling K
- Bowman C
- Boyce T
- Bradulskis S
- Bradulskis S
- Bratu M
- Bratu MR
- Bratu R-M
- Braungart S
- Bray LD
- Breaud J
- Breistrand M
- Breitenstein S
- Breslin R
- Brincat SD
- Broch A
- Brogden T
- Brown D
- Brown E
- Brown J
- Brown J
- Browning DRL
- Brunoni B
- Bsisu I
- Bucci L
- Bugaev N
- Bugeja R
- Buisson P
- Bukari M
- Bunting D
- Burger S
- Burmistrovas A
- Burns H
- Bustangi N
- Butt MT
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- Cabala Chiong JA
- Cacurri A
- Cadogan DD
- Cahill R
- Cakaloglu HC
- Caliman C
- Callan R
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- Cameron B
- Camilleri GM
- Camilleri-Brennan J
- Camilleri-Brennan J
- Camilleri-Brennan JF
- Camilo Correa J
- Campagnaro T
- Canta Calua A
- Capito C
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- Careta MC
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- Carmela Lapitan M
- Carmona JM
- Carpio J
- Carrasco N
- Carreira J-A
- Carreiro De Freitas AV
- Cassar K
- Castro Mollo M
- Catani M
- Cautiero R
- Caydiid H
- Cecilia T
- Celik S
- Cengiz TB
- Cengiz Y
- Cengiz Y
- Cengiz Y
- Cengiz Y
- Ceriani C
- Cevik M
- Chabok A
- Chachulski W
- Chai C-A
- Chai FY
- Chambers A
- Chambers A
- Chan E
- Chan L
- Chan T-YK
- Chan XW
- Chan Z
- Chandrakumar C
- Chang K
- Chang KY-C
- Chapman A
- Chapman SJ
- Charles A
- Cheah AEZ
- Chen CY
- Chen KY
- Chen T-L
- Chenn R
- Cheong YJ
- Chetta N
- Cheung YHE
- Chew LS
- Chhabra S
- Chibuye C
- Chidambaram S
- Chiesa D
- Chilton G
- Chin PX
- Chin YR
- Chiu S
- Chiu S
- Chiu SMY
- Choi J
- Choi P
- Chong BFHK
- Chong CL
- Chong CL
- Chong CL
- Chong CS
- Chong H-Y
- Chong HY
- Choudhry A
- Chow CYN
- Chowdhury A
- Chowdhury D
- Chu K
- Chun A
- Chun T
- Chung KJ
- Chung S
- Ciccioli E
- Cirocchi R
- Ciubotaru C
- Claire R
- Clarissa A
- Clark DJ
- Clark T
- Clegg-Lampety J-N
- Clegg-Lamptey J-N
- Clement KD
- Clements JM
- Clerico G
- Clifford C
- Cloro LM
- Coasaca Huaraya R
- Coccolini F
- Coccolini F
- Coccolini F
- Coccolini F
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- Cocorullo G
- Cohen DM
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- Cole S
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- Coletti M
- Colombani J-F
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- Confalonieri G
- Conlon KC
- Connor K
- Connor K
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- Contreras Urquizu M
- Contreras Vergara AL
- Contreras E
- Coomber R
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- Cornick J
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- Corro-Diaz S
- Costa C
- Costa-Maia J
- Costa-Maia J
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- Costas-Chavarri A
- Courboin E
- Court E
- Cox D
- Cox M
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- Cragg J
- Craus-Miguel A
- Cross K
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- Cruz H
- Cucumazzo S
- Cullen F
- Curletti G
- Currow C
- Currow C
- D'aguzan N
- D'Amours S
- D'amours SK
- D'cruz R
- D'Souza MS
- D'Souza R
- Da Silva LA
- Dabboor M
- Dabbour K
- Dabessa D
- Dablouk M
- Dablouk MO
- Dagoe E
- Dahy A
- Dainius E
- Dakubo J
- Dal Canto M
- Dalli J
- Dally C
- Dambrauskas Z
- Dambrauskas Z
- Dan I
- Danelli P
- Daniels I
- Daniyan M
- Danys D
- Dao W
- Daqeeq A
- Dar M
- Dar W
- Dardenne S
- Darweesh M
- Darwish AKZ
- Das A
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- Das S
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- Dashnyam E
- Dassah V
- Datta U
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- Dayie M
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- De Luca E
- De Marco P
- De Sousa AV
- Deal R
- Dean R
- Deane C
- Debrah S
- Deckelbaum DL
- Decker E
- Dedekind B
- Dedey F
- Deichsel F
- Del Basso C
- del Pilar Paucar A
- Delforge X
- Dell A
- Dempster E
- Denakpo M
- Denewar A
- Depalma N
- Deputy M
- Der Y
- Dervenis C
- Despotidis V
- Desta S
- Deutschmann P
- Devadasar GH
- Dharamshi HA
- Dhillon D
- Di Franco F
- Di Martino N
- Di Saverio S
- Di Saverio S
- Diab A
- Diaconescu B
- Diaconescu I-B
- Dias S
- Diaz Vico T
- Diaz-Jover P
- Diaz-Zorrilla C
- Dick L
- Dickfos M
- Dickson L
- Dijan E
- Dimech T
- Din F
- Dindyal S
- Dindyal S
- Dione Parreno-Sacdalan M
- Dissanayake T
- Djivoh F
- Domini E
- Domini E
- Donnelly P
- Donoghue D
- Dorani RMNR
- Dorisme A
- dos Santos DV
- Dossou F
- Doughan S
- Doughty J
- Dousset B
- Dragatas D
- Drake TM
- Drake TM
- Drake TM
- Driscoll A
- Drungilas M
- Du Plessis D
- du Plooy F
- Du Toit F
- Duane T
- Dubois A
- Duffy L
- Duhoranenayo D
- Duinhouwer L
- Dulskas A
- Dwydar A
- Ebdewi H
- Ebidy M
- Ebidy MM
- Ebrahim OS
- Eduard P
- Edwards J
- Edye M
- Eid MM
- Eisner L
- Ekow M
- El Ashal G
- El Dahab AA
- El Deen KN
- El Gendy A
- El Gendy NH
- El Halawany M
- El Jamassi A
- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Sayed GS
- El Sayed IM
- El Shoura Y
- El-badawy HA
- El-Dien KS
- El-Dien KS
- El-Din RA
- El-Din SA
- El-Gizawy E
- El-Hamouly AS
- El-Kashef H
- El-Latif NK
- El-Ma'doul AS
- El-Rabaa S
- El-Sagheer N
- El-Sawy A
- El-Sehily A
- El-Shahat NS
- El-Sheemy H
- El-Taher E
- Elabdin HZ
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem AA
- Elazoul M
- Elbanby E
- Elbanby ES
- Elbatahgy A
- Elbe P
- Elbermawy M
- Elbisomy KH
- Eldafrawy M
- Eldamaty L
- Eldeeb AZ
- Eldeen EA
- Eldin MAB
- EldosoukyMohammed A
- Elebute O
- Elebute O
- Elena G
- Elfarargy A
- Elfeki H
- Elfeki H
- Elfiky M
- Elfil M
- Elfouly N
- Elfouly N
- Elfouly Y
- Elfouly Y
- Elgebaly A
- Elgendy AH
- Elgendy FI
- Elgheriany M
- Elhadad A
- Elhadary NM
- Elhadry S
- Elhalawany E
- Elhamouly S
- Elhelbawy MS
- Elhendawy A
- Elhendawy AOA
- Elhoseny G
- Elhusseiny AAE
- Elizabeth Lopez C
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
- Elkelany A
- Elkelany A
- Elkhadrawi M
- Elkhalek EA
- Elkholy A
- Elkholy SS
- Elkolaly SS
- Elkorashy AM
- Ellison Q
- Elmashala A
- Elmasry M
- Elmelegy R
- Elmihy S
- Elnagar A
- Elnajjar MA
- Elnemr AE
- Elrazek AA
- Elsabbagh N
- Elsameea AA
- Elsawahly DME
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
- Elsayed NAR
- Elsayed ZM
- Elsebaaye AO
- Elsehimy M
- Elsemelawy R
- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay AE
- Elshami M
- Elshanwany S
- Elsharkawy AA
- Elsheikh S
- Elsherbiney S
- Elsherbiny AS
- Elsherif FA
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy DEAA
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escalante Salas MDC
- Espin-Basany E
- Espinoza F
- Essam A
- Essam AA
- Essam M
- Essoun S
- Esteban E
- Estee MM
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
- Etwire V
- Evajelista CV
- Evans D
- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
- Faboya O
- Faccincani R
- Fadel A
- Fahiem A
- Fahim M
- Fahmy MAB
- Fahy C
- Fairfield C
- Fairfield C
- Fairfield C
- Fairfield C
- Fakher R
- Falaschi F
- Falco N
- Falzon M
- Farag A
- Farag S
- Farah A
- Farahat MM
- Faraz A
- Fares M
- Farhad M
- Farhan-Alanie MMH
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk SAM
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy AM
- Fattah AA
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe CO
- Fergany A
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fergusson SJ
- Fermani C
- Fermani CG
- Fernandes C
- Fernandez C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald JE
- Fitzgerald JE
- Florez Farfan ES
- Foco M
- Fok CYJ
- Fontana T
- Foo CC
- Forlin L
- Forno W
- Fouad A
- Fouad D
- Fouad D
- Fourcade L
- Fowler AJ
- Fozard T
- Fozard T
- Frade F
- Fraga GP
- Francisco Roxas M
- Franco H
- Francois P
- Francois-Coridon H
- Francone E
- Freitas AV
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
- Furqan MM
- Gaafar S
- Gaarder T
- Gad A
- Gad MO
- Gadelkarim M
- Gadhvi V
- Gado A
- Gaignard E
- Gaignard E
- Gaizauskas V
- Gala T
- Gala T
- Galiqi G
- Galleano R
- Gallo G
- Galloway S
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- Yildirim R
- Yip C
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- Yoganathan P
- Yolcu S
- Yong CO
- Yong GL
- Younis A
- Youssef D
- Youssef H
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- Zaa'treh R
- Zachariades D-C
- Zadoroznas A
- Zahran D
- Zakaria E
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- Zapata Ponze De Leon M
- Zapata F
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- Zerihun AB
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- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
- Author
- Aamir Faiqa Binte
- Aamir Syed Roohan
- Ababneh Adnan
- Abbal Muhammad Anas
- Abbas Ahmed M
- Abbas Mostafa
- Abd-Albain Montasir A
- Abdalei Abdulwahab
- Abdalla Ahmed
- Abdalla Ahmed Yassir
- Abdalla Mohamed Galal Ali
- Abdalla Zainab
- Abdallah Mohamed M
- Abdalmahmoud Noon Ezzeldien
- Abdalsadeg Rowa
- Abdelaal Ahmed M
- Abdelbagi Alnazeer Y
- Abdelbaky Mostafa
- Abdelbaset Doaa
- AbdElbaset Esraa
- Abdelbast Menhag
- Abdelfatah Mohammed Abdelnasser
- Abdelgawad Samia
- Abdelhamid Mohamed M
- Abdeljaber Mahmoud
- Abdelkhalig Mubarak
- Abdelmaksoud Mohamed
- Abdelmeguid Rana
- Abdelmelek Dhia Errahmane
- Abdelnaeam Samah
- Abdelnasser Mohammad K
- Abdelrahim Najwa
- Abdelrahman Amira
- Abdelrahman Ayman
- Abdelsalam Hebatalla
- Abdelsamed Enas Abdelbaset
- Abdelwahab Khaled
- Abdoun Meriem
- Abdulali Fatima
- Abdulaziz Mohamed
- Abdulla Dheba Almukhtar
- Abdullah Bahiyah
- Abdullah Bahiyah
- Abdullah Walaa
- Abdullahi Habiba Ibrahim
- Abdulrahman Ahmed
- Abdulrasheed Lubabatu
- Abdulwahed Eman
- Abdulwahed Eman
- Abeysirigunawardana Dewmi
- Abidin Muhammad Fihmi Zainal
- Abiola Olukayode
- Abiyere Henry
- Abodina Ahmed Mohammed
- Aboelela Reham
- AboElfarh Hadeer Elsaeed
- Aboudlal Husein
- AbouHiekal Osama
- Aboulfotouh Ahmed
- Abozid Anwaar
- Abubaker Noora
- Abubaker Noora
- Abufanas Asma
- Abughanima Mahmoud
- Abuhashem Shehab
- Abulafia Daniel
- Abushaala Fatima
- Abushanab Khaled
- AbuShawareb Issa
- Abuuqteish Hamza
- Abuzaho Amany
- Achem Arome
- Adam Eithar
- Adam Mohammed
- Adam Mohammed A
- Addalla Mohamed
- Addley Jordan
- Adeleye Gbadebo
- Adeniyi Adebayo
- Adewole Nathaniel
- Adeyemo Olabisi
- Adeyeye Ademola
- Adeyeye Ademola
- Adly Michael
- Adnan Siti Nasyirah Nisya
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adze Joel Amwe
- Afeikhena Ehis
- Agida Teddy
- Agilla Hamza
- Agnew Emilie
- Agu Joy Onyekachi
- Ahmad Zatul Akmar
- Ahmed Abdalla
- Ahmed Ahmed
- Ahmed Ahmed
- Ahmed Alaaaldeen
- Ahmed Entisar
- Ahmed Habeeba
- Ahmed Hatem
- Ahmed Reem
- Ahmed Rehab
- Ahmed Rihab
- Ahmed Rogia Ahmed Abdalla
- Ahmed Ruaa
- Ahmed Sharwany
- Ahmed Uzair
- Ahmed Wahiba
- Ahmeed Sultan
- Airede Lydia Regina
- Aitchison Lori
- Ajredini Mirac
- Ajulo Adeshina A
- Akaba Godwin
- Akasha Mazin
- Akbar Maha Ghulam
- Akbuz Seyma Orcan
- Akdere Hakan
- Akın Bilge
- Akkaya Ege Nur
- Akpamgbo Chukwunonso Nnamdi
- Akwaisah Ayoub
- Al Hammoud Amr
- Al Rawashdeh Toka
- Al-Baw Mahmoud
- Al-Dahdouh Mosheer
- Al-Haek Safa’
- Al-Hazaimeh Mo'ath
- Al-issawi Dima
- Al-Issawi Subhi
- Al-jammal Maryam
- Al-Juaifari Maytham A
- Al-Mwajeh Tesneem
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- Zaed Moahmed
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- Zaheer Adil
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- Zakaria Ahmed
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- Zakaria Mohd Zaim
- Zalloum Jihad
- Zamanbandhon Bushra
- Zambon Mattia
- Zapsalis Konstantinos
- Zargar Kamran
- Zarzour Mohamed A
- Zeng Raymond
- Zeng Raymond
- Zengin Kagan
- Zertuche Juventino Tadeo Guerrero
- Zhang Caitlin
- Zhang Edward
- Zhang Shane
- Zhang Yichi
- Zhao Hailin
- Zheng Helen
- Zhou Karen
- Zhou Yida
- Ziergiebel Felix
- Zou Peishan
- Zuylekom Kate Van
- Zuylekom Katie Van
- Zwain Yasir Adnan
- Zyul'korneeva Sof'ya
- Aladna Abdallah
- Aljoumaa Abdullah
- Nawfal Hamdi
- Niazi Ammar
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
Mortality of emergency abdominal surgery in high-, middle- and low-income countries
- Author
- A A Ahmed Ata
- A A Ibrahem
- A A Maghrabi
- A A Nasir
- A A Ne'ma Abdullah
- A Abd El Galeel
- A Abdel-Rahman Al-Aarag
- A AbdelFattah
- A Abdelgelil
- A Abdelkareem
- A Abdelmotaleb Ghazy
- A Aber
- A Abo El Magd
- A Abo Elazayem
- A Aboarab
- A Abouelnasr
- A Abouzahra
- A Adebanjo
- A Adekoya
- A Adel
- A Adel
- A Ademuyiwa
- A Adeniyi
- A Adesina
- A Adesuyi
- A Adeyeye
- A Afandy
- A Agarwal
- A Ahmed
- A Al-Mallah
- A Al-Shammari
- A Aldalaq
- A Ali
- A Ali
- A Alkammash
- A Allegri
- A Almallah
- A Almoflihi
- A Alrifaie
- A Altaf
- A Altamimi
- A Althwainy
- A Arenas
- A Ashton
- A Atef Omar
- A Austraite
- A B Zerihun
- A Badr
- A Badwy
- A Baird
- A Bamicha
- A Benevento
- A Bhangu
- A Bhargava
- A Birring
- A Boddy
- A Bondurri
- A Bonnard
- A C Manchego Bautista
- A C Manchego Bautista
- A C Roslani
- A C Snaith
- A Cacurri
- A Chambers
- A Chambers
- A Chapman
- A Chowdhury
- A Chun
- A Daltri Lazzarini Cury
- A Daqeeq
- A Das
- A Diab
- A Driscoll
- A Dubois
- A Dwydar
- A E Ajao
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- A E Ward
- A Echevarria Rosas Moran
- A El Gendy
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- A Elbatahgy
- A Elgebaly
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- A Elkelany
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- A Fadel
- A Fahiem
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- A Faraz
- A Farquharson
- A Faure
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- A G N Robertson
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- A Gharib
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- A Vlachogiorgos
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- A Watts
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- Abid Bin Mahamood
- B Albeladi
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- B Pereira Silvestre
- B S Kumar
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- C A Arroyo Basto
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- D Mapasse
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- E Abington
- E Adel Sayma
- E Ali Ahmed
- E Aljohani
- E Aljohani
- E Alnawam
- E Alqahtani
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- E Borg
- E Borin
- E Brown
- E Chan
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- E E Howie
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- L Jennings
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- L Marples
- L Mauro
- L Napolitano
- L Nymo
- L Parkinson
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- L Richardson
- L Rodriguez
- L S Chew
- L S García
- L Sabeeh
- L Sarmento Tatagiba
- L Shi Yeo
- L Turati
- L Urbanavicius
- L Yallop
- L-A Mercado Rodriguez
- L-J Anyanwu
- M A Alfarsi
- M A Baky Fahmy
- M A E H Mohamed
- M A Fathi Abozyed
- M Abbas
- M Abd El Slam
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- M Abdelraheim
- M Abdelshafy
- M Abdulgawad
- M Abdulkhalek Habeeb
- M Abo Raya
- M Aboraya
- M Abozaid
- M Abuseif
- M Afzal
- M Agius
- M Aguilera
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- M Aledrisy
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- M Ali Yavuz
- M Aljiffry
- M Alkhouri
- M Allam
- M Alrahawy
- M Alrajraji
- M AlRowais
- M Alsaggaf
- M Alzahrani
- M Alzahrani
- M Ameen
- M Amer
- M Ammar
- M Amreia
- M Angel Paludi
- M Asal
- M Ashur Sherif
- M Attard
- M Baheeg
- M Bakhaidar
- M Baldacchino
- M Benger
- M Beuran
- M Bezzina
- M Boal
- M Boijsen
- M Boshnaq
- M Bukari
- M C Mendoza Arango
- M C Mendoza Arango
- M C Mendoza Arango
- M Carlucci
- M Cassa Careta
- M Castro Mollo
- M Contreras Urquizu
- M Dablouk
- M Dal Canto
- M Dar
- M Darweesh
- M Deputy
- M Dickfos
- M Edye
- M Elashmawy
- M Elazoul
- M Elbermawy
- M Elfil
- M Elkhadrawi
- M Elsayed
- M Elsayed
- M Elsehimy
- M Elshaer
- M Elshobary
- M Elsiddig
- M Elzayat
- M Etman
- M F Leung
- M Farhad
- M Farid Hosh
- M Firdouse
- M Gamal Mohamad Hamad
- M Gemeah
- M Ghassan Alwafai
- M Ghetia
- M Ghetia
- M Ghoneem
- M Gillespie
- M Gimzewska
- M Gomah
- M Goodstein
- M Griffiths
- M Gumar
- M Habib Ibrahim
- M Hache-Marliere
- M Hafez
- M Hampton
- M Hanafy
- M Hanrahan
- M Hanrahan
- M Hanrahan
- M Hashish
- M Hassan
- M Hassanain
- M Hemmila
- M Hjertberg
- M Hogea
- M Hussain
- M Husseini
- M I Villegas
- M Ismail
- M Jacobe
- M Jarmin
- M Jawaid
- M Jha
- M Jokubauskas
- M K Kang
- M Karakahya
- M Karkeet
- M Kennedy
- M Kesinger
- M Khajanchi
- M Khalili
- M Kimaro
- M Kontos
- M L Pimenta
- M Leal
- M Linares Delgado
- M Livingston
- M Lopez
- M M Furqan
- M M Hassan Mohammed
- M M Metwally
- M M Palliyil
- M Machaca
- M Mahmoud
- M Makinde
- M Marta Modolo
- M Mayasari
- M Mccarthy
- M Mccarthy
- M Mendez
- M Mesalam
- M Mezeil Telfah
- M Mlotshwa
- M Moamen Mohamed
- M Mohan
- M Monteleone
- M Montrimaite
- M Moron Munhoz
- M Morsi
- M Mousa
- M Mustafa
- M Mustafa
- M Nasr
- M Nirumal Kumar
- M O Dablouk
- M O'Neill
- M Oludara
- M Orchard
- M Osman
- M Othman
- M Pasini
- M Peycelon
- M Puttick
- M Puttick
- M Rabie
- M Radic
- M Ramcharn
- M Rangarajan
- M Rashad
- M Rashid
- M Rashid Minhas Qadir
- M Rodriguez Castro
- M S Ali Muhammad Gohar
- M S J Wilson
- M S J Wilson
- M S Weinstein
- M Saad
- M Sabry Ammar
- M Saeed
- M Saeed
- M Salama
- M Salma
- M Scott
- M Seif
- M Seisa
- M Shaalan
- M Shawki
- M Siguantay
- M Sion
- M Spurr
- M Stoddart
- M Sund
- M Swaroop
- M Sykes
- M Taher
- M Tun
- M Turner
- M Utter
- M Varcada
- M Vartic
- M Vella-Baldacchino
- M Wagener
- M Warda
- M Worku
- M Young-Han Kim
- M Zakir
- M Zalabia
- M Zapata Ponze De Leon
- M Zapata Ponze De Leon
- M Zidan
- M Zikry
- M Zuber
- N A Nik Abdullah
- N Abd El Hamid
- N Ahmed Attallah
- N Akeel
- N Badwi
- N Behar
- N Benons
- N Blencowe
- N Botto
- N Bugaev
- N D'aguzan
- N Elfouly
- N Elsayed
- N F Watson
- N Ghandora
- N Gobin
- N Gouvas
- N Green
- N Gyanchandani
- N Hall
- N Harrison
- N Herrera
- N J Hall
- N J Smart
- N J Wright
- N Kaselis
- N Limaye
- N M Urbina Rojas
- N Maple
- N Mcintyre
- N Mendez
- N Muralha
- N Ngayu
- N Nikoloudis
- N Osman
- N Panait
- N Pezelj
- N Phillips
- N R Kosai
- N Robertson
- N S Abebe
- N S Mitroudis
- N Sadig
- N Seyoum Abebe
- N Sishuba
- N Soltani
- N Soubhy El-Shahat
- N Starr
- N Yosri Elsayed Abdel-Wahab
- N Zanini
- O Abbo
- O Adesanya
- O Aguilera
- O Al-Obaedi
- O Alahmady
- O Algohary
- O Azzam
- O Bouali
- O Elebute
- O Faturoti
- O Garaycochea
- O Javed
- O Javed
- O Komolafe
- O Mohamed
- O Mosalum
- O Nasher
- O O Ayandipo
- O Oshodi
- O Osman
- O Saadeldeen Ebrahim
- O Salah
- O Seifelnasr
- O Sherief Abd El Hameed
- O Taiwo
- O Todd
- O Warren
- O Wiliams
- O Ziff
- P A Assouto
- P Acharya
- P Alves Bezerra Morais
- P C Munipalle
- P Capleton
- P Danelli
- P De Bono
- P Eduard
- P Harbord
- P Harrison
- P Holton
- P J Lim
- P Jackson
- P Jain
- P Karumnas
- P Kielty
- P Labib
- P Malik
- P Mentula
- P Paolo Grandinetti
- P Patel
- P Pitigala Arachchi
- P Ramazzini
- P Sarmah
- P Silvani
- P Singh
- P Sodde
- P Stassen
- P Sutton
- P Sutton
- P Thomson
- P Ugalde
- P Weber
- P Weber
- P Witherspoon
- P-O Lundgren
- Q Alimi
- Q Alimi
- R Adams
- R Allott
- R Alvarado Jaramillo
- R Alyami
- R Alyami
- R Amandito
- R Anderson
- R Araujo
- R Ardley
- R Balmaceda
- R Barrionuevo Ojeda
- R Beyene
- R Blundell
- R Bowe
- R Bugeja
- R Cahill
- R Camacho
- R Chenn
- R Cirocchi
- R Coasaca Huaraya
- R Coomber
- R D Obute
- R D S Omara
- R D'cruz
- R Darío Arias Pacheco
- R Davenport
- R Dean
- R Elmelegy
- R F Staerkle
- R Faccincani
- R Fakher
- R George
- R Gilbert
- R Goh Ern Tze
- R Gratton
- R Guevara
- R Harrison
- R K M Jawad Al-Hasani
- R Kamil
- R Karlo
- R Kennedy
- R Kerley
- R King
- R Lages Simoes
- R Lawther
- R Lilford
- R M H Balila
- R Macchiavello
- R Mcdonald
- R Mcintosh
- R Mcintyre
- R Melo
- R Moore
- R Morton
- R Osuoji
- R Oumer
- R Pranevicius
- R Rackauskas
- R Rajan
- R Rakauskas
- R Riauka
- R Rivas
- R Rodríguez-Uría
- R Sakr
- R Satoskar
- R Schmid
- R Shah
- R Shaker
- R Shaker
- R Slade
- R Soley
- R Som
- R Spence
- R Thurairaja
- R Tyler
- R Villa
- R W Gilbert
- R Zilinskiene
- R-M Bratu
- S A Alnuqaydan
- S A Durand
- S Abd Elmageed Barakat
- S Abdelghany
- S Abdoun Ishag Idris
- S Ahlqvist
- S Al Awwad
- S Al-Nahrawi
- S Aldhafeeri
- S Aljohani
- S Almuallem
- S Altaf Naqvi
- S Anderson Khouri Ferreira
- S Antar
- S Aql
- S Arman
- S Ayad
- S Ayyar
- S B Shu Yip
- S Basson
- S Batista Lemaire
- S Bhat
- S Bhattacharya
- S Binna Kim
- S Bokhari
- S Botes
- S Bradulskis
- S Braungart
- S Breitenstein
- S Chhabra
- S Chidambaram
- S Chiu
- S Chung
- S Corro-Diaz Gonzalez
- S Cucumazzo
- S Das
- S Desta
- S Di Saverio
- S Dias
- S Dindyal
- S Doughan
- S El Mesery
- S El-Rabaa
- S Elshanwany
- S Elsheikh
- S Elsobky
- S Estupinian
- S F Ashraf
- S Fergusson
- S G Gosling
- S Galloway
- S Germanos
- S Ghanem
- S Giuliani
- S Gokani
- S Gosling
- S Hafiz
- S Haines
- S Hallam
- S Hassan
- S Highcock
- S Hossaini
- S Hussein
- S Irtan
- S Itopa Suleiman
- S J Chapman
- S J Lim
- S Juciute
- S K D'amours
- S K Pitt
- S Karandikar
- S Khan
- S Kharsa
- S King
- S Koh
- S Kruspi
- S Kumar
- S Kushwaha
- S Limache
- S Loizides
- S M Contreras Mérida
- S M Lakhani
- S M Sundstrom
- S Magdy Ahmed
- S Mahdi
- S Man Yeng Chiu
- S Mcaleer
- S Mehrez
- S Mikalauskas
- S Mitrasinovic
- S Mouttalib
- S Nadkarni
- S Ng
- S Nigo
- S O'Neill
- S Olori
- S Pai
- S Parthiban
- S Ramzi
- S Ray
- S Rayne
- S Razmdjou
- S Roncali
- S Roy
- S S Prasad
- S Saad
- S Said Elkolaly
- S Samy
- S Sani Ali
- S Sarsik
- S Sarwary
- S Satoskar
- S Shaikh
- S Shehata
- S Sheth
- S Shu
- S Sierra
- S Singh
- S Sinha
- S Sivaganesh
- S Stock
- S Tabiri
- S Talukder
- S Talukder
- S Tewari
- S Tharmalingam
- S Tou
- S V Kinnera
- S Vivekanantham
- S Ward
- S Wondimu
- S Zegarra
- S Zeidan
- S-H Kim
- S-P Hosein
- T A M Malik
- T Akeem Lawal
- T Alzayat
- T Arulampalam
- T B Wold
- T Barker
- T Boyce
- T Brogden
- T Chun
- T Clark
- T E Glover
- T Ebogo Ngwa
- T F Jones
- T Falconer Hall
- T Farooq
- T Fautz
- T Fernandes Giuriato
- T Fozard
- T Fozard
- T Khan
- T Kumar
- T M Drake
- T Mak
- T Muhammad Yaseen
- T Naqvi
- T Newton
- T Nouh
- T O'Connor
- T Pezas
- T Poskus
- T Razek B Marinkovic
- T S Hettiarachchi
- T Sherman
- T Stasinou
- T Urbonas
- T W Tilston
- T White
- T Xerri
- T Yaseen
- U Alamoudi
- U Gunnarsson
- U Gustafsson
- U Hantour
- U Karabacak
- U Walsh
- V Ambrozeviciute
- V Beisa
- V D Palomino Castillo
- V Despotidis
- V Gadhvi
- V Graffeille
- V Graffieille
- V Grassi
- V J P Nsengimana
- V Jennings
- V Jotautas
- V K Proctor
- V Kong
- V M Quintero Riaza
- V Parent
- V Patel
- V Punja
- V Sallinen
- V Shatkar
- V Summerour
- V Thanusan
- W Adham
- W Anwer
- W Beasley
- W C Ho
- W C Soon
- W Chachulski
- W Forno
- W Guo
- W Hawkins
- W Ho
- W Hutch
- W J Lossius
- W L Messa Aguilar
- W L Messa Aguilar
- W Milligan
- W Milligan
- W Pino
- W S Li
- W S M Kithsiri Janakantha Senanayake
- Y Abd El Salam
- Y Abd Elrasoul
- Y Abd-Elrasoul
- Y Aigrain
- Y Cengiz
- Y El Shoura
- Y Elfouly
- Y Hegazy
- Y Ibrahim
- Y Imorou Souaibou
- Y Macchitella
- Y N Neo
- Y P Mogan
- Y Rajjoub
- Y Reddy
- Y Salama
- Y Sinha
- Z Chan
- Z Dambrauskas
- Z Hassan
- Z Iftikhar
- Z Jaffry
- Z Mikwar
- Z Oof
- Z Urniezius
- Z Zhang
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2016
- Field of study
Background: Surgical mortality data are collected routinely in high-income countries, yet virtually no low- or middle-income countries have outcome surveillance in place. The aim was prospectively to collect worldwide mortality data following emergency abdominal surgery, comparing findings across countries with a low, middle or high Human Development Index (HDI).
Methods: This was a prospective, multicentre, cohort study. Self-selected hospitals performing emergency surgery submitted prespecified data for consecutive patients from at least one 2-week interval during July to December 2014. Postoperative mortality was analysed by hierarchical multivariable logistic regression.
Results: Data were obtained for 10 745 patients from 357 centres in 58 countries; 6538 were from high-, 2889 from middle- and 1318 from low-HDI settings. The overall mortality rate was 1⋅6 per cent at 24 h (high 1⋅1 per cent, middle 1⋅9 per cent, low 3⋅4 per cent; P < 0⋅001), increasing to 5⋅4 per cent by 30 days (high 4⋅5 per cent, middle 6⋅0 per cent, low 8⋅6 per cent; P < 0⋅001). Of the 578 patients who died, 404 (69⋅9 per cent) did so between 24 h and 30 days following surgery (high 74⋅2 per cent, middle 68⋅8 per cent, low 60⋅5 per cent). After adjustment, 30-day mortality remained higher in middle-income (odds ratio (OR) 2⋅78, 95 per cent c.i. 1⋅84 to 4⋅20) and low-income (OR 2⋅97, 1⋅84 to 4⋅81) countries. Surgical safety checklist use was less frequent in low- and middle-income countries, but when used was associated with reduced mortality at 30 days.
Conclusion: Mortality is three times higher in low- compared with high-HDI countries even when adjusted for prognostic factors. Patient safety factors may have an important role. Registration number: NCT02179112 (http://www.clinicaltrials.gov)
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
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- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay Ae
- Elshami M
- Elshanwany S
- Elsharkawy Aa
- Elsheikh S
- Elsherbiney S
- Elsherbiny As
- Elsherif Fa
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy Deaa
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escobar Eg.
- Espin-Basany E
- Espinoza F
- Espinoza Kt
- Espinoza Kt
- Essam A
- Essam Aa
- Essam M
- Essoun S
- Esteban E
- Estee Mm
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
- Etwire V
- Evajelista Cv
- Evans D
- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
- Faboya O
- Faccincani R
- Fadel A
- Fahiem A
- Fahim M
- Fahy C
- Fairfield C
- Fairfield C
- Fairfield C
- Fakher R
- Falaschi F
- Falco N
- Falzon M
- Farag A
- Farag S
- Farah A
- Farahat Mm
- Faraz A
- Fares M
- Farfan Esf
- Farhad M
- Farhan-Alanie Mmh
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk Sam
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy Am
- Fattah Aa
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
- Fergusson Sj
- Fergusson Sj
- Fermani C
- Fermani Cg
- Ferná
- Fernandes C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferreira Sak
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald Je
- Florez Ljg
- Foco M
- Fok Cyj
- Fontana T
- Foo Cc
- Forlin L
- Forno W
- Fouad A
- Fouad D
- Fouad D
- Fourcade L
- Fowler Aj
- Fozard T
- Fozard T
- Frade F
- Fraga Gp
- Franco H
- Francois P
- Francois-Coridon H
- Francone E
- Freitas Av
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
- Furqan Mm
- Gü
- Gü
- Gaafar S
- Gaarder T
- Gad A
- Gad Mo
- Gadelkarim M
- Gadhvi V
- Gado A
- Gaiž
- Gaignard E
- Gaignard E
- Gala T
- Gala T
- Galiqi G
- Galleano R
- Gallo G
- Galloway S
- Galvez Cp
- Gamal D
- Gamal E
- Gamal H
- Gamal S
- Gamaly E
- Gamil D
- Gan C
- Gan Yy
- Gani Ma
- Garaycochea O
- Garcí
- Garcí
- Garcí
- Garcia-Florez L
- Garcia-Marin Ja
- Garcia-Perez Jm
- Garland A
- Gash K
- Gash K
- Gash K
- Gastaldi P
- Gasteratos K
- Gaujoux S
- Gavagna L
- Gbessi Dg
- Gemeah M
- Gemenetzis G
- Gemenetzis G
- George R
- Germanos S
- Germanos S
- Gerosa A
- Gerosa A
- Geuoshy A
- Ghaben A
- Ghandora N
- Ghanem A
- Ghanem E
- Ghanem S
- Ghanem S
- Ghannam M
- Gharib A
- Gharib A
- Ghazy Aa
- Gheith A
- Ghetia M
- Ghetia M
- Ghonaim Ma
- Ghoneem M
- Ghoneim O
- Giacci L
- Giardino Fr
- Giavarini L
- Giglio Mc
- Gilbert R
- Gilbert Rw
- Giles J
- Gillespie M
- Gimzewska M
- Giraldo Rsr
- Giuliani S
- Giuliani S
- Giuriato Tf
- Gkiokas G
- Glasbey J
- Glasbey J
- Glasbey Jc
- Glasbey Jc
- Glover Te
- Glover-Addy H
- Glynn M
- Gobin N
- Gobin N
- Goh Cc
- Goh Cc
- Goh W
- Gohar Meam
- Gokani S
- Goldin E
- Golding D
- Gomaa A
- Gomah M
- Gonzalez M
- Gonzalez Sc
- Goodstein M
- Gosling S
- Gosling Sg
- Gouda A
- Gould L
- Gouldthorpe C
- Gouvas N
- Gouws J
- Graffeille V
- Graffieille V
- Gran M
- Grandinetti Pp
- Grant A
- Grasset E
- Grasset E
- Grassi V
- Gratton R
- Gravante G
- Gravante G
- Gray D
- Grech N
- Green N
- Grella Mg
- Gribauskaite J
- Griffiths E
- Griffiths E
- Griffiths M
- Grima T
- Grisin E
- Grizhja B
- Grobler Dc
- Grosos C
- Grossart C
- Guasti Bpsj
- Gudal A
- Gudal A
- Gudal A
- Gudlaugsdottir K
- Guevara R
- Guglielmo V
- Gui D
- Gulbinas A
- Gulcicek Ob
- Gulielmi A
- Gultom Pa
- Gumar M
- Gunaseelan K
- Gunawan R
- Guner A
- Gunnarsson U
- Guo W
- Gupta A
- Gustafsson U
- Gyamfi Fe
- Gyanchandani N
- Gyedu A
- Habeeb Ma
- Habeeb O
- Habeebullah A
- Hache-Marliere M
- Haddad N
- Hafez At
- Hafez M
- Hafez M
- Hafez S
- Haffreingue A
- Hafiz S
- Hagan R
- Hagar A
- Haines M
- Haines S
- Hajeh H
- Hakim H
- Halhouli O
- Halhouli O
- Halicioglu I
- Hall E
- Hall N
- Hall Nj
- Hall Tf
- Hallam S
- Haloho A
- Hamad Mgm
- Hamaguchi Jlh
- Hamarshi A
- Hamasaki J
- Hamdan A
- Hamdan M
- Hamed Mf
- Hamill D
- Hammad A
- Hammad A
- Hammad Am
- Hampton M
- Hampton Mi
- Hamsho W
- Hanafy M
- Hand C
- Hanks A
- Hanley I
- Hanoun S
- Hanrahan M
- Hanrahan M
- Hanrahan M
- Hanrahan M
- Hantour U
- Hantour U
- Hany E
- Haque M
- Har Pa
- Haraux E
- Harbord P
- Haroun A
- Harper E
- Harrison Em
- Harrison Em
- Harrison N
- Harrison P
- Harrison R
- Hartford L
- Harvey N
- Hasan A
- Hasan A
- Hasan D
- Hasanah A
- Hasanain D
- Hascoet J
- Hashad E
- Hasheminia A
- Hashim A
- Hashish A
- Hashish M
- Haslegrave A
- Hasnan Mb
- Hassaan A
- Hassaan A
- Hassan A
- Hassan A
- Hassan A
- Hassan Ata
- Hassan I
- Hassan M
- Hassan Omm
- Hassan S
- Hassan Z
- Hassanain M
- Hassanain M
- Hassanein Ab
- Havemann I
- Hawkins W
- Heard R
- Heath J
- Heffernan D
- Hegazy Em
- Hegazy Y
- Helene Fc
- Helguero-Santin Lm
- Hemeda D
- Hemingway D
- Hemmila M
- Hemmila M
- Henderson L
- Henderson L
- Heng He
- Henric N
- Henry F
- Henshall De
- Herebat A
- Herikstad R
- Herrera N
- Herrera-Matta J
- Herrod P
- Hervieux E
- Hervieux E
- Hesham O
- Hettiarachchi Ts
- Hewage K
- Heywood Eg
- Highcock S
- Hilal K
- Hinojosa C
- Hjertberg M
- Hjertberg M
- Hmila S
- Ho A
- Ho Cw
- Ho W
- Ho Wc
- Hodonou F
- Hogea M
- Holte S
- Holton P
- Homeida A
- Hoogakker E
- Horobjowsky A
- Hosein Sp
- Hosh M
- Hossaini S
- Hossameldin A
- Houlden C
- Howells L
- Howie Ee
- Hrora A
- Huaman E
- Huaraya Rc
- Humm G
- Hunter K
- Hussain M
- Hussein A
- Hussein S
- Husseini M
- Husseiny R
- Hutch W
- Huwait A
- Iş
- Iacono C
- Iannone I
- Ibraheem Aa
- Ibraheem Hi
- Ibrahem Aa
- Ibrahem Aa
- Ibrahim A
- Ibrahim A
- Ibrahim A
- Ibrahim Am
- Ibrahim E
- Ibrahim Em
- Ibrahim I
- Ibrahim K
- Ibrahim M
- Ibrahim Mh
- Ibrahim Y
- Idress T
- Idris F
- Idris Sai
- Iftekhar F
- Iftikhar Z
- Iftikhar Z
- Ignatavicius P
- Ihediwa G
- Imoro O
- Ingabire Jca
- Ingabire Jca
- Ingabire Jca
- Ioannidis O
- Iordache Fm
- Iqbal Fm
- Iqbal Mr
- Ireland P
- Irtan S
- Irtan S
- Irwin G
- Irwin G
- Irwin G
- Irwin G
- Ishak N
- Iskandar F
- Ismaï
- Ismaï
- Ismaï
- Ismaï
- Ismail A
- Ismail M
- Ismail M
- Ismail Mjb
- Ismail Mk
- Ismail Sa
- Israelsson L
- Ivros N
- Iyer D
- Iyer D
- Iyer D
- Jabal Ms
- Jabbar A
- Jaber S
- Jackson P
- Jacobe M
- Jaffry Z
- Jaffry Z
- Jaich R
- Jain P
- Jama Gm
- Jamal L
- Janardha Kc
- Janik M
- Jankus T
- Jaradat D
- Jaramillo Ra
- Jarmin M
- Jasaitis K
- Javaid M
- Javed O
- Javed O
- Jawaid M
- Jayathilake Ab
- Jck Ng
- Jean-Francois C
- Jeffery A
- Jeffery A
- Jenner E
- Jennings L
- Jennings V
- Jennings V
- Jensen E
- Jenvey C
- Jeo Ws
- Jeon H
- Jeremic L
- Jethwani Dl
- Jeyakumar J
- Jeyakumar J
- Jha M
- Jimenez J
- Jimenez-Morillas P
- Joel Lwl
- Johanna N
- Johnson K
- Johnston R
- Jokubauskas M
- Jokubauskas M
- Jokubonis K
- Jones C
- Jones C
- Jones E
- Jones Tf
- Jonnalagadda R
- Joosten J
- Jordan H
- Jotautas V
- Jotautas V
- Jovine E
- Jovine E
- Jubran Af
- Juciute S
- Julaihi R
- Jurdell E
- Kaafarani H
- Kabariti R
- Kabariti R
- Kabba J
- Kabongo K
- Kache S
- Kaci Aa
- Kadiwar S
- Kalakouti E
- Kalles V
- Kalles V
- Kalles V
- Kamarajah Sk
- Kamarulzamil Sna
- Kamil R
- Kamya S
- Kanani A
- Kandil Am
- Kandil H
- Kang Mk
- Kanta Th
- Karabacak U
- Karabelias G
- Karabulut K
- Karahan Sr
- Karakahya M
- Karandikar S
- Karandikar S
- Kariem N
- Karim A
- Karim R
- Karim S
- Karismaningtyas H
- Karjiker P
- Karkeet M
- Karkeet M
- Karlo R
- Karlo R
- Karousos D
- Karumnas P
- Kaselis N
- Kaselis N
- Kasem E
- Kasem Ea
- Kasputyte S
- Kaul A
- Kazanavicius D
- Kedar A
- Kefalidi E
- Keke Kr
- Kelany M
- Kenibar A
- Kennedy Ed
- Kennedy M
- Kennedy R
- Keogh K
- Kerley R
- Kershaw S
- Kesinger M
- Khafagy T
- Khairy H
- Khairy H
- Khajanchi M
- Khaled H
- Khalifah E
- Khalili M
- Khalique A
- Khallaf S
- Khamajeet A
- Khan A
- Khan K
- Khan Ma
- Khan R
- Khan S
- Khan T
- Khan Za
- Kharsa S
- Khatri C
- Khatri C
- Khattab K
- Khedr Aeh
- Khg Li
- Khoja A
- Khoja A
- Khokha D
- Khokha V
- Khosla S
- Khreishi R
- Khreishi R
- Khulu Lb
- Khyrallh A
- Kiasat A
- Kidd T
- Kielty P
- Kim My
- Kim Sb
- Kim Sh
- Kimaro M
- Kinandu K
- King R
- King S
- King S
- Kinnera Sv
- Kiran Rp
- Kirby A
- Kirishnan A
- Kirupagaran A
- Kiudelis M
- Kjellin A
- Kkk Li
- Klappenbach R
- Knight S
- Koay Kl
- Kobal Bb
- Koh C
- Koh H
- Koh Py
- Koh S
- Koh S
- Kojo Att
- Kojo Att
- Kojo Att
- Kolosov A
- Komolafe O
- Kondrotas P
- Kong C
- Kong Sn
- Kong V
- Kong V
- Konstantina K
- Kontos M
- Kordorwu Hek
- Korkolis D
- Kosai Nr
- Kosai Nr
- Kose E
- Koskenvuo L
- Kostov E
- Kotb Ahe
- Kotecha D
- Koto Mz
- Kotobi H
- Koumpa F
- Kouraklis G
- Kourdouli A
- Kourdouli A
- Kretzmann H
- Krishna K
- Kruspi S
- Kufeji D
- Kulasabanathan K
- Kuliavas J
- Kumar B
- Kumar B
- Kumar B
- Kumar Bs
- Kumar Mn
- Kumar S
- Kumar S
- Kumar S
- Kumar S
- Kumar T
- Kumwenda D
- Kushwaha S
- Kushwaha S
- Kusi K
- Kutkevicius J
- Kwakyeafriyie P
- Kwatiwani C
- Kwizera S
- Kwok Sh
- Kyereh M
- Kyriazanos I
- Kyrou G
- Kyziridis D
- Ló
- L&apos
- La Brocca A
- la Medina AR
- la Medina AR
- la Medina AR
- Labib P
- Ladukas A
- Lafferty K
- Lagunavicius K
- Lai Ac
- Lakhani Sm
- Lakshmi Hn
- Lam Fy
- Lam Jcy
- Lam Wh
- Lamanna Gl
- Lanau Miv
- Lando J
- Landolfo G
- Landolfo G
- Lap G
- Lapitan Mc
- Lapitan Mc
- Larsen Jw
- Lasek A
- Lasheen A
- Lasheen Kt
- Latif A
- Laufer Lav
- Laugzemys E
- Laugzemys E
- Laurie K
- Lauzikas G
- Law Jh
- Lawal A
- Lawal Ao
- Lawal T
- Lawal Ta
- Lawani I
- Lawther R
- Lazzari G
- Lazzari V
- Leal A
- Leal M
- Lecompte Jf
- Lee C
- Lee Ex
- Lee F
- Lee K
- Lee Kc
- Lee Ky
- Lee Tsb
- Lemaire Sb
- Leone N
- Leong Fqh
- Leppä
- Leppä
- Leroux J
- Leung Kw
- Leung Mf
- Leusink A
- Lewis J
- Li Ws
- Licari L
- Lieske B
- Lieske B
- Liew I
- Liew I
- Lilford R
- Lilford R
- Lilford Rj
- Lim G
- Lim H
- Lim J
- Lim Pj
- Lim Sj
- Lim Sj
- Lim Sy
- Limache S
- Limaye N
- Limoges B
- Lintin L
- Lipnickas V
- Litvin A
- Liu Q
- Liu Q
- Livesey A
- Livingston M
- Ljuhar D
- Lo Conte A
- Loaloa Mr
- Lockey J
- Lohse Has
- Lohse Has
- Loizides S
- Lokman Maa
- Longstaff L
- Lopez Ce
- Lopez Lip
- Lopez M
- Lopez M
- Lopez-Arevalo C
- Lorenzon L
- Lossius Wj
- Loughran D
- Low X
- Luc Ar
- Luck J
- Luck J
- Luck J
- Luglio G
- Lund J
- Lund J
- Lundgren Po
- Luque Gb
- Luque L
- Luque L
- Lytras D
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- Má
- Mé
- Mü
- Mañ
- Ma J
- Mabitsela Me
- Mabrouk M
- Macchiavello R
- Macchitella Y
- Macchitella Y
- Macdermid E
- Macdonald A
- Macdonald E
- Macdonald L
- Maceviciute K
- Macfarlane A
- Machaca M
- Maciejec L
- Madiba T
- Madkor Mh
- Maffioli A
- Maffioli A
- Magdy A
- Magdy B
- Magdy E
- Magdy H
- Magdy M
- Magdy S
- Magee C
- Maghrabi A
- Maghrabi Aa
- Magri D
- Mahamood Ab
- Mahanty S
- Maharaj G
- Mahdi A
- Mahdi S
- Mahdi S
- Maher Me
- Mahmoud B
- Mahmoud H
- Mahmoud M
- Mahmoud Ma
- Mahmoud Mi
- Mahmoud S
- Mahmoud Sme
- Mahmud K
- Maillot B
- Maimbo M
- Maimbo M
- Mairs Ng
- Maison K
- Maistry N
- Majauskyté
- Majbar A
- Majid Ahha
- Majid K
- Major Cp
- Major P
- Major P
- Mak T
- Mak T
- Makama J
- Makinde M
- Makupe A
- Malavenda M
- Malik K
- Malik P
- Malik Ta
- Mamdouh E
- Mamdouh R
- Manatakis Dk
- Manfreda S
- Mangan C
- Mangan C
- Mangiapane M
- Manipal Ce
- Maniscalco A
- Mann T
- Mannu Gs
- Manriquez-Reyes M
- Mansor Ey
- Mansour B
- Mansour S
- Mansuri A
- Mao P
- Mapasse D
- Maple N
- Maraie N
- Marey A
- Marey As
- Margaritis M
- Mariani A
- Marinkovic B
- Marinos C
- Marks E
- Marples L
- Marret Jb
- Marshall Dc
- Martian Bv
- Martin A
- Mas R
- Mason C
- Mata Lps
- Matheu A
- Mathew Sw
- Matos-Puig R
- Matta Jjh
- Mattar O
- Matter Sm
- Mauro L
- Mayasari M
- Mazelyte R
- Mazrimas P
- Mazzella A
- Mcaleer E
- Mcaleer S
- Mccarthy K
- Mccarthy M
- Mccarthy M
- McCullagh D
- Mcdonald R
- McGarvie S
- Mcguigan A
- McIntosh K
- Mcintosh R
- Mcintyre Cj
- Mcintyre N
- Mcintyre R
- Mckechnie D
- Mclachlan G
- Mclean Al
- Mclean K
- McMorran D
- Mcnish D
- Mcphee A
- Mealy K
- Mehdi A
- Mehrez S
- Mejia Agv
- Melo R
- Melo R
- Mendel H
- Mendez M
- Mendez N
- Mendizabal Caa
- Mendoza I
- Menegussi J
- Mensah E
- Menshawy A
- Mentula P
- Meqbil J
- Mericliler M
- Merlini D
- Merlini D
- Merlo Ms
- Mesbah N
- Meshref A
- Metwally Mm
- Migliore M
- Miguel Gps
- Mihaljevic Al
- Mihanovic J
- Mihanovic J
- Mijuskovic B
- Mikalauskas S
- Mikalauskas S
- Mikuckyte D
- Mikwar Z
- Milligan W
- Milligan W
- Mingrone P
- Minguez G
- Minocha A
- Minocha A
- Miranda C
- Mircea H
- Mirghani D
- Mironescu A
- Mironescu A
- Mironescu As
- Mironescu As
- Mirza A
- Mirza S
- Mistry A
- Mitrasinovic S
- Mitroudi M
- Mitroudis N
- Mittal A
- Mitul Ar
- Mitul Ar
- Miyasato Hs
- Mizzi C
- Mizzi S
- Mlotshwa M
- Moaty M
- Mochet S
- Modolo Mm
- Modolo Mm
- Modolo Mm
- Moe Tt
- Mogan Yp
- Moghazy Me
- Mohamed A
- Mohamed A
- Mohamed Am
- Mohamed Ar
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed Ma
- Mohamed Maeh
- Mohamed Mm
- Mohamed O
- Mohamed Sr
- Mohameden A
- Mohammad A
- Mohammad A
- Mohammed A
- Mohammed A
- Mohammed Ae
- Mohammed Ar
- Mohammed H
- Mohammed Mm
- Mohammed Mmh
- Mohammed S
- Mohan H
- Mohan M
- Mohan M
- Mok Yt
- Mokhtar A
- Molina G
- Mollo Mc
- Monaghan E
- Monaghan E
- Monrad-Hansen Pw
- Montejo Msg
- Monteleone M
- Monteleone M
- Montes I
- Montes I
- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
- Moore R
- Mora Jjv
- Morais Pab
- Morales C
- Moran Aer
- Morandi E
- Moreira G
- Moreno Sc
- Morgan C
- Morgan C
- Morshedy Em
- Morsi A
- Morsi M
- Morton D
- Morton D
- Morton R
- Mosad A
- Mosalum O
- Mostafa Ha
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
- Mphatsoe Am
- Mshelbwala P
- Msiska N
- Msosa V
- Msosa V
- Muddebihal U
- Mukin Adf
- Muktar U
- Mukuzunga C
- Muller C
- Muller C
- Munera A
- Munhoz Mm
- Munipalle Pc
- Muntean L
- Muntean Li
- Muralha N
- Murphy J
- Murray A
- Murutoglu B
- Musa Aek
- Musleh A
- Musowoya J
- Mussad A
- Mustafa M
- Mustafa M
- Mustafa Ma
- Musyoka Ck
- Mutabazi Az
- Mutabazi Az
- Mutlu D
- Mutlu V
- Muzio E
- Myers J
- Mykoniatis I
- Næ
- Nabawi A
- Nada F
- Nadeem N
- Nadkarni S
- Nagy Gs
- Nahar Sn
- Nair H
- Nanthakumaran S
- Napolitano L
- Napolitano L
- Naqvi Sa
- Naqvi T
- Naranjo Aristizã
- Narayanan R
- Narayanan R
- Narvestad Jk
- Nashaat A
- Nashat M
- Nasher O
- Nashidengo P
- Nasir A
- Nasir Aa
- Nasr A
- Nasr M
- Nasr M
- Nassif D
- Nastri G
- Natalie H
- Nataraja R
- Natili A
- Navarro A
- Nawara C
- Nawawi A
- Nawawi A
- Nayel Ar
- Nazir M
- Ndajiwo A
- Ndajiwo A
- Ndegwa W
- Ndlovu Sr
- Ndwambi P
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- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
Recommended from our members
Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Ababneh Hazim S
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbasgholizadeh Rouzbeh
- Abbasi-Kangevari Mohsen
- Abbasian Mohammadreza
- Abbastabar Hedayat
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdelwahab Ahmed
- Abdollahi Mohammad
- Abdollahifar Mohammad-Amin
- Abdoun Meriem
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abebe Mesfin
- Abebe Samrawit Shawel
- Abedi Aidin
- Abegaz Kedir Hussein
- Abhilash E S
- Abidi Hassan
- Abiodun Olumide
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abolmaali Meysam
- Abouzid Mohamed
- Aboye Girma Beressa
- Abreu Lucas Guimarães
- Abrha Woldu Aberhe
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- Starodubova Antonina V
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- Uddin Sayed Mohammad Nazim
- Udoakang Aniefiok John
- Udoh Arit
- Ullah Atta
- Ullah Irfan
- Ullah Saeed
- Ullah Sana
- Umakanthan Srikanth
- Umeokonkwo Chukwuma David
- Unim Brigid
- Unnikrishnan Bhaskaran
- Unsworth Carolyn Anne
- Upadhyay Era
- Urso Daniele
- Usman Jibrin Sammani
- Vahabi Seyed Mohammad
- Vaithinathan Asokan Govindaraj
- Valizadeh Rohollah
- Van de Velde Sarah M
- Van den Eynde Jef
- Varga Orsolya
- Vart Priya
- Varthya Shoban Babu
- Vasankari Tommi Juhani
- Vasic Milena
- Vaziri Siavash
- Vellingiri Balachandar
- Venketasubramanian Narayanaswamy
- Verghese Nicholas Alexander
- Verma Madhur
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Vervoort Dominique
- Villafañe Jorge Hugo
- Villanueva Gabriela Ines
- Vinayak Manish
- Violante Francesco S
- Viskadourou Maria
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Vo Bay
- Vollset Stein Emil
- Vongpradith Avina
- Vos Theo
- Vujcic Isidora S
- Vukovic Rade
- Wafa Hatem A
- Waheed Yasir
- Wamai Richard G
- Wang Cong
- Wang Ning
- Wang Shu
- Wang Song
- Wang Yanzhong
- Wang Yuan-Pang
- Waqas Muhammad
- Ward Paul
- Wassie Emebet Gashaw
- Watson Stefanie
- Watson Stephanie Louise Watson
- Weerakoon Kosala Gayan
- Wei Melissa Y
- Weintraub Robert G
- Weiss Daniel J
- Westerman Ronny
- Whisnant Joanna L
- Wiangkham Taweewat
- Wickramasinghe Dakshitha Praneeth
- Wickramasinghe Nuwan Darshana
- Wilandika Angga
- Wilkerson Caroline
- Willeit Peter
- Wilson Shadrach
- Wojewodzic Marcin W
- Woldegebreal Demewoz H
- Wolf Axel Walter
- Wolfe Charles D A
- Wondimagegene Yohannes Addisu
- Wong Yen Jun
- Wongsin Utoomporn
- Wool Eve E
- Wu Ai-Min
- Wu Chenkai
- Wu Felicia
- Wu Xinsheng
- Wu Zenghong
- Xia Juan
- Xiao Hong
- Xie Yang
- Xu Suowen
- Xu Wang-Dong
- Xu Xiaoyue
- Xu Yvonne Yiru
- Yadollahpour Ali
- Yamagishi Kazumasa
- Yang Danting
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Yaribeygi Habib
- Ye Pengpeng
- Yehualashet Sisay Shewasinad
- Yesiltepe Metin
- Yesuf Subah Abderehim
- Yezli Saber
- Yi Siyan
- Yigezu Amanuel
- Yip Paul
- Yismaw Malede Berihun
- Yismaw Yazachew
- Yiğit Arzu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- Yoon Seok-Jun
- You Yuyi
- Younis Mustafa Z
- Yousefi Zabihollah
- Yu Chuanhua
- Yu Yong
- Yuh Faith H
- Zadey Siddhesh
- Zadnik Vesna
- Zafari Nima
- Zakham Fathiah
- Zaki Nazar
- Zaman Sojib Bin
- Zamora Nelson
- Zand Ramin
- Zangiabadian Moein
- Zar Heather J
- Zare Iman
- Zarrintan Armin
- Zeariya Mohammed G M
- Zeinali Zahra
- Zhang Haijun
- Zhang Jianrong
- Zhang Jingya
- Zhang Liqun
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhong Chenwen
- Zhou Juexiao
- Zhu Bin
- Zhu Lei
- Ziafati Makan
- Zielińska Magdalena
- Zitoun Osama A
- Zoladl Mohammad
- Zou Zhiyong
- Zuhlke Liesl J
- Zumla Alimuddin
- Zweck Elric
- Zyoud Samer H
- Ärnlöv Johan
- Šekerija Mario
- Publication venue
- Elsevier
- Publication date
- 03/04/2024
- Field of study
BACKGROUND Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mortality rates and life expectancy allow comparisons of the consequences of causes of death globally and over time, providing a nuanced understanding of the effect of these causes on global populations. METHODS The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 cause-of-death analysis estimated mortality and years of life lost (YLLs) from 288 causes of death by age-sex-location-year in 204 countries and territories and 811 subnational locations for each year from 1990 until 2021. The analysis used 56 604 data sources, including data from vital registration and verbal autopsy as well as surveys, censuses, surveillance systems, and cancer registries, among others. As with previous GBD rounds, cause-specific death rates for most causes were estimated using the Cause of Death Ensemble model-a modelling tool developed for GBD to assess the out-of-sample predictive validity of different statistical models and covariate permutations and combine those results to produce cause-specific mortality estimates-with alternative strategies adapted to model causes with insufficient data, substantial changes in reporting over the study period, or unusual epidemiology. YLLs were computed as the product of the number of deaths for each cause-age-sex-location-year and the standard life expectancy at each age. As part of the modelling process, uncertainty intervals (UIs) were generated using the 2·5th and 97·5th percentiles from a 1000-draw distribution for each metric. We decomposed life expectancy by cause of death, location, and year to show cause-specific effects on life expectancy from 1990 to 2021. We also used the coefficient of variation and the fraction of population affected by 90% of deaths to highlight concentrations of mortality. Findings are reported in counts and age-standardised rates. Methodological improvements for cause-of-death estimates in GBD 2021 include the expansion of under-5-years age group to include four new age groups, enhanced methods to account for stochastic variation of sparse data, and the inclusion of COVID-19 and other pandemic-related mortality-which includes excess mortality associated with the pandemic, excluding COVID-19, lower respiratory infections, measles, malaria, and pertussis. For this analysis, 199 new country-years of vital registration cause-of-death data, 5 country-years of surveillance data, 21 country-years of verbal autopsy data, and 94 country-years of other data types were added to those used in previous GBD rounds. FINDINGS The leading causes of age-standardised deaths globally were the same in 2019 as they were in 1990; in descending order, these were, ischaemic heart disease, stroke, chronic obstructive pulmonary disease, and lower respiratory infections. In 2021, however, COVID-19 replaced stroke as the second-leading age-standardised cause of death, with 94·0 deaths (95% UI 89·2-100·0) per 100 000 population. The COVID-19 pandemic shifted the rankings of the leading five causes, lowering stroke to the third-leading and chronic obstructive pulmonary disease to the fourth-leading position. In 2021, the highest age-standardised death rates from COVID-19 occurred in sub-Saharan Africa (271·0 deaths [250·1-290·7] per 100 000 population) and Latin America and the Caribbean (195·4 deaths [182·1-211·4] per 100 000 population). The lowest age-standardised death rates from COVID-19 were in the high-income super-region (48·1 deaths [47·4-48·8] per 100 000 population) and southeast Asia, east Asia, and Oceania (23·2 deaths [16·3-37·2] per 100 000 population). Globally, life expectancy steadily improved between 1990 and 2019 for 18 of the 22 investigated causes. Decomposition of global and regional life expectancy showed the positive effect that reductions in deaths from enteric infections, lower respiratory infections, stroke, and neonatal deaths, among others have contributed to improved survival over the study period. However, a net reduction of 1·6 years occurred in global life expectancy between 2019 and 2021, primarily due to increased death rates from COVID-19 and other pandemic-related mortality. Life expectancy was highly variable between super-regions over the study period, with southeast Asia, east Asia, and Oceania gaining 8·3 years (6·7-9·9) overall, while having the smallest reduction in life expectancy due to COVID-19 (0·4 years). The largest reduction in life expectancy due to COVID-19 occurred in Latin America and the Caribbean (3·6 years). Additionally, 53 of the 288 causes of death were highly concentrated in locations with less than 50% of the global population as of 2021, and these causes of death became progressively more concentrated since 1990, when only 44 causes showed this pattern. The concentration phenomenon is discussed heuristically with respect to enteric and lower respiratory infections, malaria, HIV/AIDS, neonatal disorders, tuberculosis, and measles. INTERPRETATION Long-standing gains in life expectancy and reductions in many of the leading causes of death have been disrupted by the COVID-19 pandemic, the adverse effects of which were spread unevenly among populations. Despite the pandemic, there has been continued progress in combatting several notable causes of death, leading to improved global life expectancy over the study period. Each of the seven GBD super-regions showed an overall improvement from 1990 and 2021, obscuring the negative effect in the years of the pandemic. Additionally, our findings regarding regional variation in causes of death driving increases in life expectancy hold clear policy utility. Analyses of shifting mortality trends reveal that several causes, once widespread globally, are now increasingly concentrated geographically. These changes in mortality concentration, alongside further investigation of changing risks, interventions, and relevant policy, present an important opportunity to deepen our understanding of mortality-reduction strategies. Examining patterns in mortality concentration might reveal areas where successful public health interventions have been implemented. Translating these successes to locations where certain causes of death remain entrenched can inform policies that work to improve life expectancy for people everywhere. FUNDING Bill & Melinda Gates Foundation
Novel non-cyclooxygenase inhibitory derivatives of naproxen for colorectal cancer chemoprevention
- Author
- Publication venue
- Springer
- Publication date
- 01/01/2014
- Field of study
A structure-based medicinal chemistry strategy was applied to design new naproxen derivatives that show growth inhibitory activity against human colon tumor cells through a cyclooxygenase (COX)-independent mechanism. In vitro testing of the synthesized compounds against the human HT-29 colon tumor cell line revealed enhanced growth inhibitory activity compared to the parent naproxen with 3a showing IC<sub>50</sub> of 11.4 μM (two orders of magnitude more potent than naproxen). Selectivity of 3a was investigated against a panel of three tumor and one normal colon cell lines and showed up to six times less toxicity against normal colonocytes. Compound 3a was shown to induce dose-dependent apoptosis of HT116 colon tumor cells as evidenced by measuring the activity of caspases-3 and 7. None of the synthesized compounds showed activity against COX-1 or COX-2 isozymes, confirming a COX-independent mechanism of action. Compound 3k was found to have no ulcerogenic effect in rats as indicated by electron microscope scanning of the stomach after oral administration. A pharmacophore model was developed for elucidating structure–activity relationships and subsequent chemical optimization for this series of compounds as colorectal cancer chemopreventive drugs