40 research outputs found
Dust Devil Tracks
Dust devils that leave dark- or light-toned tracks are common on Mars and they can also be found on the Earth’s surface. Dust devil tracks (hereinafter DDTs) are ephemeral surface features with mostly sub-annual lifetimes. Regarding their size, DDT widths can range between ∼1 m and ∼1 km, depending on the diameter of dust devil that created the track, and DDT lengths range from a few tens of meters to several kilometers, limited by the duration and horizontal ground speed of dust devils. DDTs can be classified into three main types based on their morphology and albedo in contrast to their surroundings; all are found on both planets: (a) dark continuous DDTs, (b) dark cycloidal DDTs, and (c) bright DDTs. Dark continuous DDTs are the most common type on Mars. They are characterized by their relatively homogenous and continuous low albedo surface tracks. Based on terrestrial and martian in situ studies, these DDTs most likely form when surficial dust layers are removed to expose larger-grained substrate material (coarse sands of ≥500 μm in diameter). The exposure of larger-grained materials changes the photometric properties of the surface; hence leading to lower albedo tracks because grain size is photometrically inversely proportional to the surface reflectance. However, although not observed so far, compositional differences (i.e., color differences) might also lead to albedo contrasts when dust is removed to expose substrate materials with mineralogical differences. For dark continuous DDTs, albedo drop measurements are around 2.5 % in the wavelength range of 550–850 nm on Mars and around 0.5 % in the wavelength range from 300–1100 nm on Earth. The removal of an equivalent layer thickness around 1 μm is sufficient for the formation of visible dark continuous DDTs on Mars and Earth. The next type of DDTs, dark cycloidal DDTs, are characterized by their low albedo pattern of overlapping scallops. Terrestrial in situ studies imply that they are formed when sand-sized material that is eroded from the outer vortex area of a dust devil is redeposited in annular patterns in the central vortex region. This type of DDT can also be found in on Mars in orbital image data, and although in situ studies are lacking, terrestrial analog studies, laboratory work, and numerical modeling suggest they have the same formation mechanism as those on Earth. Finally, bright DDTs are characterized by their continuous track pattern and high albedo compared to their undisturbed surroundings. They are found on both planets, but to date they have only been analyzed in situ on Earth. Here, the destruction of aggregates of dust, silt and sand by dust devils leads to smooth surfaces in contrast to the undisturbed rough surfaces surrounding the track. The resulting change in photometric properties occurs because the smoother surfaces have a higher reflectance compared to the surrounding rough surface, leading to bright DDTs. On Mars, the destruction of surficial dust-aggregates may also lead to bright DDTs. However, higher reflective surfaces may be produced by other formation mechanisms, such as dust compaction by passing dust devils, as this may also cause changes in photometric properties. On Mars, DDTs in general are found at all elevations and on a global scale, except on the permanent polar caps. DDT maximum areal densities occur during spring and summer in both hemispheres produced by an increase in dust devil activity caused by maximum insolation. Regionally, dust devil densities vary spatially likely controlled by changes in dust cover thicknesses and substrate materials. This variability makes it difficult to infer dust devil activity from DDT frequencies. Furthermore, only a fraction of dust devils leave tracks. However, DDTs can be used as proxies for dust devil lifetimes and wind directions and speeds, and they can also be used to predict lander or rover solar panel clearing events. Overall, the high DDT frequency in many areas on Mars leads to drastic albedo changes that affect large-scale weather patterns
Field Measurements of Terrestrial and Martian Dust Devils
Surface-based measurements of terrestrial and martian dust devils/convective vortices provided from mobile and stationary platforms are discussed. Imaging of terrestrial dust devils has quantified their rotational and vertical wind speeds, translation speeds, dimensions, dust load, and frequency of occurrence. Imaging of martian dust devils has provided translation speeds and constraints on dimensions, but only limited constraints on vertical motion within a vortex. The longer mission durations on Mars afforded by long operating robotic landers and rovers have provided statistical quantification of vortex occurrence (time-of-sol, and recently seasonal) that has until recently not been a primary outcome of more temporally limited terrestrial dust devil measurement campaigns. Terrestrial measurement campaigns have included a more extensive range of measured vortex parameters (pressure, wind, morphology, etc.) than have martian opportunities, with electric field and direct measure of dust abundance not yet obtained on Mars. No martian robotic mission has yet provided contemporaneous high frequency wind and pressure measurements. Comparison of measured terrestrial and martian dust devil characteristics suggests that martian dust devils are larger and possess faster maximum rotational wind speeds, that the absolute magnitude of the pressure deficit within a terrestrial dust devil is an order of magnitude greater than a martian dust devil, and that the time-of-day variation in vortex frequency is similar. Recent terrestrial investigations have demonstrated the presence of diagnostic dust devil signals within seismic and infrasound measurements; an upcoming Mars robotic mission will obtain similar measurement types
Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study
Objectives: Physical inactivity and sedentary behaviour are associated with higher breast cancer risk in observational studies, but ascribing causality is difficult. Mendelian randomisation (MR) assesses causality by simulating randomised trial groups using genotype. We assessed whether lifelong physical activity or sedentary time, assessed using genotype, may be causally associated with breast cancer risk overall, pre/post-menopause, and by case-groups defined by tumour characteristics.
Methods: We performed two-sample inverse-variance-weighted MR using individual-level Breast Cancer Association Consortium case-control data from 130 957 European-ancestry women (69 838 invasive cases), and published UK Biobank data (n=91 105–377 234). Genetic instruments were single nucleotide polymorphisms (SNPs) associated in UK Biobank with wrist-worn accelerometer-measured overall physical activity (nsnps=5) or sedentary time (nsnps=6), or accelerometer-measured (nsnps=1) or self-reported (nsnps=5) vigorous physical activity.
Results: Greater genetically-predicted overall activity was associated with lower breast cancer overall risk (OR=0.59; 95% confidence interval (CI) 0.42 to 0.83 per-standard deviation (SD;~8 milligravities acceleration)) and for most case-groups. Genetically-predicted vigorous activity was associated with lower risk of pre/perimenopausal breast cancer (OR=0.62; 95% CI 0.45 to 0.87,≥3 vs. 0 self-reported days/week), with consistent estimates for most case-groups. Greater genetically-predicted sedentary time was associated with higher hormone-receptor-negative tumour risk (OR=1.77; 95% CI 1.07 to 2.92 per-SD (~7% time spent sedentary)), with elevated estimates for most case-groups. Results were robust to sensitivity analyses examining pleiotropy (including weighted-median-MR, MR-Egger).
Conclusion: Our study provides strong evidence that greater overall physical activity, greater vigorous activity, and lower sedentary time are likely to reduce breast cancer risk. More widespread adoption of active lifestyles may reduce the burden from the most common cancer in women
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
Using the Cap Analysis of Gene Expression (CAGE) technology, the FANTOM5 consortium provided one of the most comprehensive maps of transcription start sites (TSSs) in several species. Strikingly, ~72% of them could not be assigned to a specific gene and initiate at unconventional regions, outside promoters or enhancers. Here, we probe these unassigned TSSs and show that, in all species studied, a significant fraction of CAGE peaks initiate at microsatellites, also called short tandem repeats (STRs). To confirm this transcription, we develop Cap Trap RNA-seq, a technology which combines cap trapping and long read MinION sequencing. We train sequence-based deep learning models able to predict CAGE signal at STRs with high accuracy. These models unveil the importance of STR surrounding sequences not only to distinguish STR classes, but also to predict the level of transcription initiation. Importantly, genetic variants linked to human diseases are preferentially found at STRs with high transcription initiation level, supporting the biological and clinical relevance of transcription initiation at STRs. Together, our results extend the repertoire of non-coding transcription associated with DNA tandem repeats and complexify STR polymorphism
CO2-cushion vehicle for Mars. An alternative locomotion for exploration rovers
In this work, consideration is given to ad hoc cushion vehicles for Mars. On Earth, air cushion vehicles use pressurized atmospheric air by means of powerful blowers that pump the air into a chamber, however, for Mars -at least for the ¿rst stages of human colonization, such an Earth-like approach seems not viable either because the low atmospheric density of Mars, the weight associated with the system or the risk of mechanical failure by handling with a dusty atmosphere. Nevertheless it is worthy to investigate if a sort of similar air-cushion vehicle for Mars because the suppression of the heavy systems associated with terrain vehicles - which reduces the available payload for experiments, and also the limited mobility of these kind of locomotion. Here, a scoping study for an ad hoc air cushion vehicle for Mars is investigated by taking advantage of Mars CO2 atmosphere and the low temperatures attained during the nights. Fundamentally the idea behind, is freezing CO2 -as dry-ice, during the Martian cold nights and then be used to levitate the vehicle above the ground by releasing the highly pressurized CO2 obtained previous sublimation during the warm day. It is shown that such a Martian surface vehicle will have a daily ¿ight limited to 10-20 minutes or thereabouts, depending of the clearance height and the weight of the vehicle. This autonomy of ¿ight per day although seems very small if compared with traditional terrain vehicles, is misleading and has to be put in context. Indeed, because the much more larger velocity attained by the cushion vehicle in comparison with terrain vehicles this will translate into an equal or even much more larger distances traveled by the cushion vehicle during a short time per day than by a terrain vehicle during prolonged times.Peer ReviewedPostprint (published version
Seasonal variations in low level flow in the NASA-Ames Mars GCM
The Martian Hadley circulation consists of two cells of different sizes at most times of the year, with one cell dominating near the solstices. The lower branch of this flow is strongly topographically controlled, especially east of the Tharsis plateau and Syrtis Major. Simulations using idealized topography show that longitudinal asymmetries in heating also play a role in forming the jets. Nearer the equinoxes, the total cross-equatorial flow intensity is reduced and the effect of the seasonal condensation flow is felt more strongly. Because of effects such as topography, zero cross-equatorial flow is not actually achieved at the equinoxes, but is slightly offset in time. Even when the mean flow is zero, the two jets are still present but flow in opposite directions: the Tharsis jet flows south and the Syrtis jet north. The latter is a result of the time-averaged effect of slope wind circulations. The two jets are still relatively intense at this time. For example, with an optical depth τ of 0.3, and at a height of 250 m, v̄ at L = 270° is about 9ms southward, while at 45°W v is 26 m s. At L = 350°, v̄ is 0.5 m s, while at 45°W it is still above 8 m s. The effect of atmospheric dust loading is also examined
On the origin of perennial water ice at the south pole of Mars: A precession-controlled mechanism?
The poles of Mars are known to have recorded recent (<107 years) climatic changes. While the south polar region appears to have preserved its million-year-old environment from major resurfacing events, except for the small portion containing the CO2 residual cap, the discovery of residual water ice units in areas adjacent to the cap provides compelling evidence for recent glaciological activity. The mapping and characterization of these H2O-rich terrains by Observatoire pour la Minéralogie, l'Eau, les Glaces et l'Activité (OMEGA) on board Mars Express, which have supplemented earlier findings by Mars Odyssey and Mars Global Surveyor, have raised a number of questions related to their origin. We propose that these water ice deposits are the relics of Mars' orbit precession cycle and that they were laid down when perihelion was synchronized with northern summer, i.e., more than 10,000 years ago. We favor precession over other possible explanations because (1) as shown by our General Circulation Model (GCM) and previous studies, current climate is not conducive to the accumulation of water at the south pole due to an unfavorable volatile transport and insolation configuration, (2) the residual CO2 ice cap, which is known to cold trap water molecules on its surface and which probably controls the current extent of the water ice units, is geologically younger, (3) our GCM shows that 21,500 years ago, when perihelion occurred during northern spring, water ice at the north pole was no longer stable and accumulated instead near the south pole with rates as high as 1 mm yr−1. This could have led to the formation of a meters-thick circumpolar water ice mantle. As perihelion slowly shifted back to the current value, southern summer insolation intensified and the water ice layer became unstable. The layer recessed poleward until the residual CO2 ice cover eventually formed on top of it and protected water ice from further sublimation. In this polar accumulation process, water ice clouds play a critical role since they regulate the exchange of water between hemispheres. The so-called “Clancy effect,” which sequesters water in the spring/summer hemisphere coinciding with aphelion due to cloud sedimentation, is demonstrated to be comparable in magnitude to the circulation bias forced by the north-to-south topographic dichotomy. However, we predict that the response of Mars' water cycle to the precession cycle should be asymmetric between hemispheres not only because of the topographic bias in circulation but also because of an asymmetry in the dust cycle. We predict that under a “reversed perihelion” climate, dust activity during northern summer is less pronounced than during southern summer in the opposite perihelion configuration (i.e., today's regime). When averaged over a precession cycle, this reduced potential for dust lifting will force a significantly colder summer in the north and, by virtue of the Clancy effect, will curtail the ability of the northern hemisphere to transfer volatiles to the south. This process may have helped create the observed morphological differences in the layered deposits between the poles and could help explain the large disparity in their resurfacing ages