Documentant l'arqueologia: la casa de Massot Avengenà a l'alfòndec del call Major de Barcelona (carrer de Sant Honorat, núm. 3)

El present article sintetitza l?estudi historicoartístic de les restes medievals trobades al jaciment arqueològic del subsòl del número 3 del carrer Sant Honorat de Barcelona, avui seu del Departament de la Presidència de la Generalitat de Catalunya, realitzat l?any 2009. Les estratigrafies més importants d?aquest excepcional jaciment ?juntament amb les d?època tardoromana? corresponen a una casa palau situada a l?alfòndec del call Major de Barcelona, de la qual es conserven bona part dels fonaments i diverses sitges de grans proporcions construïdes a mitjan segle xiii. A partir de les dades facilitades per l?arqueologia, de la bibliografia existent i de documentació arxivística parcialment inèdita, s?ha pogut reconstruir la història de la finca entre els segles xiv i xix, però sobretot en un període clau per a la història de la ciutat: el pogrom de 1391, la desaparició de l?aljama barcelonina i l?establiment de les elits urbanes cristianes a l?antic call. En aquell moment, la casa passà de mans del darrer propietari jueu, el financer Massot Avengenà, al primer estadant cristià, el jurista Pere de Rajadell.Documenting archaeology: Massot Avengenà?s house in the corn exchange in Barcelona?s call Major (number 3, Carrer de Sant Honorat). The article outlines the historical and artistic study carried out in 2009 on the medieval remains found at the archaeological site in the subsoil of number 3, Carrer Sant Honorat in Barcelona, where the Government of Catalonia?s Presidential Office is currently located. This exceptional site?s most important stratigraphies (alongside those from the late Roman period) correspond to a house/palace located in the corn exchange in Barcelona?s call Major (the largest section of the city?s medieval Jewish quarter). A significant portion of the building?s foundations have been preserved, along with a number of large silos constructed in the mid-13th century. The information obtained through archaeological work and the existing bibliography and partially unpublished archive documents have made it possible to reconstruct the history of the property between the 14th and 19th centuries, particularly during a key period in the city?s past, encompassing the pogrom of 1391, the disappearance of Barcelona?s aljama (a Spanish term of Arabic origin used in old official documents to designate self-governing communities of Moors and Jews living under Spanish rule) and the settling of the urban Christian elite in the old Jewish quarter. During this period, the house ceased to belong to the financier Massot Avengenà, its last Jewish owner, and became the property of the jurist Pere de Rajadell, its first Christian resident

El conflicto entre cristianos y musulmanes en las relaciones de sucesos : la liberación de Buda

Este trabajo propone el análisis de una selección de textos escritos en romance sobre la derrota turca y la toma de la ciudad de Buda en 1686, que denuncian la exultante acogida popular de la noticia de las gestas cristianas en Centroeuropa, la percepción del eterno conflicto entre Oriente y Occidente y la proyección del imaginario colectivo del siglo xvii acerca de la lucha contra los infieles.This paper offers the analysis of a selection of texts, written in Romance languages, about the Turkish defeat and the conquest of the city of Buda in 1686, which provide evidence of the popular exultation at the news of the Christian achievements in Central Europe, the perception of the eternal conflict between East and West, and the projection of the seventeenth-century collective imagination regarding the struggle against the infidel

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Documentant l'arqueologia: la casa de Massot Avengenà a l'alfòndec del call Major de Barcelona (carrer de Sant Honorat, núm. 3)

El present article sintetitza l?estudi historicoartístic de les restes medievals trobades al jaciment arqueològic del subsòl del número 3 del carrer Sant Honorat de Barcelona, avui seu del Departament de la Presidència de la Generalitat de Catalunya, realitzat l?any 2009. Les estratigrafies més importants d?aquest excepcional jaciment ?juntament amb les d?època tardoromana? corresponen a una casa palau situada a l?alfòndec del call Major de Barcelona, de la qual es conserven bona part dels fonaments i diverses sitges de grans proporcions construïdes a mitjan segle xiii. A partir de les dades facilitades per l?arqueologia, de la bibliografia existent i de documentació arxivística parcialment inèdita, s?ha pogut reconstruir la història de la finca entre els segles xiv i xix, però sobretot en un període clau per a la història de la ciutat: el pogrom de 1391, la desaparició de l?aljama barcelonina i l?establiment de les elits urbanes cristianes a l?antic call. En aquell moment, la casa passà de mans del darrer propietari jueu, el financer Massot Avengenà, al primer estadant cristià, el jurista Pere de Rajadell.Documenting archaeology: Massot Avengenà?s house in the corn exchange in Barcelona?s call Major (number 3, Carrer de Sant Honorat). The article outlines the historical and artistic study carried out in 2009 on the medieval remains found at the archaeological site in the subsoil of number 3, Carrer Sant Honorat in Barcelona, where the Government of Catalonia?s Presidential Office is currently located. This exceptional site?s most important stratigraphies (alongside those from the late Roman period) correspond to a house/palace located in the corn exchange in Barcelona?s call Major (the largest section of the city?s medieval Jewish quarter). A significant portion of the building?s foundations have been preserved, along with a number of large silos constructed in the mid-13th century. The information obtained through archaeological work and the existing bibliography and partially unpublished archive documents have made it possible to reconstruct the history of the property between the 14th and 19th centuries, particularly during a key period in the city?s past, encompassing the pogrom of 1391, the disappearance of Barcelona?s aljama (a Spanish term of Arabic origin used in old official documents to designate self-governing communities of Moors and Jews living under Spanish rule) and the settling of the urban Christian elite in the old Jewish quarter. During this period, the house ceased to belong to the financier Massot Avengenà, its last Jewish owner, and became the property of the jurist Pere de Rajadell, its first Christian resident

Documentant l'arqueologia: la casa de Massot Avengenà a l'alfòndec del call Major de Barcelona (carrer de Sant Honorat, núm. 3)

El present article sintetitza l?estudi historicoartístic de les restes medievals trobades al jaciment arqueològic del subsòl del número 3 del carrer Sant Honorat de Barcelona, avui seu del Departament de la Presidència de la Generalitat de Catalunya, realitzat l?any 2009. Les estratigrafies més importants d?aquest excepcional jaciment ?juntament amb les d?època tardoromana? corresponen a una casa palau situada a l?alfòndec del call Major de Barcelona, de la qual es conserven bona part dels fonaments i diverses sitges de grans proporcions construïdes a mitjan segle xiii. A partir de les dades facilitades per l?arqueologia, de la bibliografia existent i de documentació arxivística parcialment inèdita, s?ha pogut reconstruir la història de la finca entre els segles xiv i xix, però sobretot en un període clau per a la història de la ciutat: el pogrom de 1391, la desaparició de l?aljama barcelonina i l?establiment de les elits urbanes cristianes a l?antic call. En aquell moment, la casa passà de mans del darrer propietari jueu, el financer Massot Avengenà, al primer estadant cristià, el jurista Pere de Rajadell.Documenting archaeology: Massot Avengenà?s house in the corn exchange in Barcelona?s call Major (number 3, Carrer de Sant Honorat). The article outlines the historical and artistic study carried out in 2009 on the medieval remains found at the archaeological site in the subsoil of number 3, Carrer Sant Honorat in Barcelona, where the Government of Catalonia?s Presidential Office is currently located. This exceptional site?s most important stratigraphies (alongside those from the late Roman period) correspond to a house/palace located in the corn exchange in Barcelona?s call Major (the largest section of the city?s medieval Jewish quarter). A significant portion of the building?s foundations have been preserved, along with a number of large silos constructed in the mid-13th century. The information obtained through archaeological work and the existing bibliography and partially unpublished archive documents have made it possible to reconstruct the history of the property between the 14th and 19th centuries, particularly during a key period in the city?s past, encompassing the pogrom of 1391, the disappearance of Barcelona?s aljama (a Spanish term of Arabic origin used in old official documents to designate self-governing communities of Moors and Jews living under Spanish rule) and the settling of the urban Christian elite in the old Jewish quarter. During this period, the house ceased to belong to the financier Massot Avengenà, its last Jewish owner, and became the property of the jurist Pere de Rajadell, its first Christian resident

Glioblastoma Treatment: State-of-the-Art and Future Perspectives

(1) Background: Glioblastoma is the most frequent and lethal primary tumor of the central nervous system. Through many years, research has brought various advances in glioblastoma treatment. At this time, glioblastoma management is based on maximal safe surgical resection, radiotherapy, and chemotherapy with temozolomide. Recently, bevacizumab has been added to the treatment arsenal for the recurrent scenario. Nevertheless, patients with glioblastoma still have a poor prognosis. Therefore, many efforts are being made in different clinical research areas to find a new alternative to improve overall survival, free-progression survival, and life quality in glioblastoma patients. (2) Methods: Our objective is to recap the actual state-of-the-art in glioblastoma treatment, resume the actual research and future perspectives on immunotherapy, as well as the new synthetic molecules and natural compounds that represent potential future therapies at preclinical stages. (3) Conclusions: Despite the great efforts in therapeutic research, glioblastoma management has suffered minimal changes, and the prognosis remains poor. Combined therapeutic strategies and delivery methods, including immunotherapy, synthetic molecules, natural compounds, and glioblastoma stem cell inhibition, may potentiate the standard of care therapy and represent the next step in glioblastoma management research

El conflicto entre cristianos y musulmanes en las relaciones de sucesos: la liberación de Buda

Este trabajo propone el análisis de una selección de textos escritos en romance sobre la derrota turca y la toma de la ciudad de Buda en 1686, que denuncian la exultante acogida popular de la noticia de las gestas cristianas en Centroeuropa, la percepción del eterno conflicto entre oriente y occidente y la proyección del imaginario colectivo del siglo xvii acerca de la lucha contra los infieles

Filosofía, Feminismo y Ficción: identidades narrativas en mundos analógicos y virtuales

Memoria del Proyecto de Innovación Educativa 7/23-24 "Filosofía, Feminismo y Ficción: identidades narrativas en mundos analógicos y virtuales", desarrollado en tres ejes: implementación de formatos audiovisuales, teatrales y multimedia en la docencia, difusión de contenidos y trabajo interno sobre la identidad personal.Depto. de Lógica y Filosofía TeóricaFac. de FilosofíaFac. de Ciencias de la InformaciónFac. de FilologíaFALSEsubmitte