663 research outputs found
Observation of a One-Dimensional Spin-Orbit Gap in a Quantum Wire
Understanding the flow of spins in magnetic layered structures has enabled an
increase in data storage density in hard drives over the past decade of more
than two orders of magnitude1. Following this remarkable success, the field of
'spintronics' or spin-based electronics is moving beyond effects based on local
spin polarisation and is turning its attention to spin-orbit interaction (SOI)
effects, which hold promise for the production, detection and manipulation of
spin currents, allowing coherent transmission of information within a device.
While SOI-induced spin transport effects have been observed in two- and
three-dimensional samples, these have been subtle and elusive, often detected
only indirectly in electrical transport or else with more sophisticated
techniques. Here we present the first observation of a predicted 'spin-orbit
gap' in a one-dimensional sample, where counter-propagating spins, constituting
a spin current, are accompanied by a clear signal in the easily-measured linear
conductance of the system.Comment: 10 pages, 5 figures, supplementary informatio
Seasonal winter forecasts and the stratosphere
Published© 2016 Royal Meteorological Society. We investigate seasonal forecasts of the winter North Atlantic Oscillation (NAO) and their relationship with the stratosphere. Climatological frequencies of sudden stratospheric warming (SSW) and strong polar vortex (SPV) events are well represented and the predicted risk of events varies between 25 and 90% from winter to winter, indicating predictability beyond the deterministic range. The risk of SSW and SPV events relates to predicted NAO as expected, with NAO shifts of -6.5 and +4.8hPa in forecast members containing SSW and SPV events. Most striking of all is that forecast skill of the surface winter NAO vanishes from these hindcasts if members containing SSW events are excluded.This work was supported by the Joint DECC/Defra Met Office
Hadley Centre Climate Programme (GA01101), the UK Public
Weather Service research program and the European Union
Framework 7 SPECS project. The contribution of AYK is funded
by FMI’s tenure track program and the Academy of Finland
under grant 286298
A Multi-Wavelength Infrared Study of NGC 891
We present a multi-wavlength infrared study of the nearby, edge-on, spiral
galaxy NGC 891. We have examined 20 independent, spatially resolved IR images
of this galaxy, 14 of which are newly reduced and/or previously unpublished
images. These images span a wavelength regime from 1.2 microns in which the
emission is dominated by cool stars, through the MIR, in which emission is
dominated by PAHs, to 850 microns, in which emission is dominated by cold dust
in thermal equilibrium with the radiation field. The changing morphology of the
galaxy with wavelength illustrates the changing dominant components. We detect
extra-planar dust emission in this galaxy, consistent with previously published
results, but now show that PAH emission is also in the halo, to a vertical
distance of z >= 2.5 kpc. We compare the vertical extents of various components
and find that the PAHs (from 7.7 and 8 micron data) and warm dust (24 microns)
extend to smaller z heights than the cool dust (450 microns). For six locations
in the galaxy for which the S/N was sufficient, we present SEDs of the IR
emission, including two in the halo - the first time a halo SED in an external
galaxy has been presented. We have modeled these SEDs and find that the PAH
fraction is similar to Galactic values (within a factor of two), with the
lowest value at the galaxy's center, consistent with independent results of
other galaxies. In the halo environment, the fraction of dust exposed to a
colder radiation field, is of order unity, consistent with an environment in
which there is no star formation. The source of excitation is likely from
photons escaping from the disk.Comment: 24 pages, 17 figures, 7 tables, accepted for publication in MNRA
Observation of a One-Dimensional Spin-Orbit Gap in a Quantum Wire
Understanding the flow of spins in magnetic layered structures has enabled an
increase in data storage density in hard drives over the past decade of more
than two orders of magnitude1. Following this remarkable success, the field of
'spintronics' or spin-based electronics is moving beyond effects based on local
spin polarisation and is turning its attention to spin-orbit interaction (SOI)
effects, which hold promise for the production, detection and manipulation of
spin currents, allowing coherent transmission of information within a device.
While SOI-induced spin transport effects have been observed in two- and
three-dimensional samples, these have been subtle and elusive, often detected
only indirectly in electrical transport or else with more sophisticated
techniques. Here we present the first observation of a predicted 'spin-orbit
gap' in a one-dimensional sample, where counter-propagating spins, constituting
a spin current, are accompanied by a clear signal in the easily-measured linear
conductance of the system.Comment: 10 pages, 5 figures, supplementary informatio
LoCuSS: Luminous infrared galaxies in the merging cluster Abell 1758 at z=0.28
We present the first galaxy evolution results from the Local Cluster
Substructure Survey (LoCuSS), a multi-wavelength survey of 100 X-ray selected
galaxy clusters at 0.15<z<0.30. LoCuSS combines far-UV through far-IR
observations of cluster galaxies with gravitational lensing analysis and X-ray
data to investigate the interplay between the hierarchical assembly of clusters
and the evolution of cluster galaxies. Here we present new panoramic
Spitzer/MIPS 24micron observations of the merging cluster Abell 1758 at z=0.279
spanning 6.5x6.5Mpc and reaching a 90% completeness limit of 400uJy. We
estimate a global cluster SFR of 910\pm320 M_sun/yr within 3 Mpc of the cluster
centre, originating from 42 galaxies with L_IR > 5x10^10 L_sun. The obscured
activity in A1758 is therefore comparable with that in Cl 0024+1654, the most
active cluster previously studied at 24um. The obscured galaxies faithfully
trace the cluster potential as revealed by the weak-lensing mass map of the
cluster, including numerous mass peaks at R~2-3Mpc that are likely associated
with infalling galaxy groups and filamentary structures. However the core
(R<500kpc) of A1758N is 2x more active in the IR than that of A1758S, likely
reflecting differences in the recent dynamical history of the two clusters. The
24micron results from A1758 therefore suggest that dust-obscured cluster
galaxies are common in merging clusters and suggests that obscured activity in
clusters is triggered by both the details of cluster-cluster mergers and
processes that operate at larger radii including those within in-falling
groups. Our ongoing far-UV through far-IR observations of a large sample of
clusters should allow us to disentangle the different physical processes
responsible for triggering obscured star formation in clusters.Comment: 13 pages, 9 figures. Accepted for publication in MNRA
The alpha 7 nicotinic receptor agonist PHA-543613 hydrochloride inhibits <i>Porphyromonas gingivalis</i>-induced expression of interleukin-8 by oral keratinocytes
Objective:
The alpha 7 nicotinic receptor (α7nAChR) is expressed by oral keratinocytes. α7nAChR activation mediates anti-inflammatory responses. The objective of this study was to determine if α7nAChR activation inhibited pathogen-induced interleukin-8 (IL-8) expression by oral keratinocytes.<p></p>
Materials and methods:
Periodontal tissue expression of α7nAChR was determined by real-time PCR. OKF6/TERT-2 oral keratinocytes were exposed to <i>Porphyromonas gingivalis</i> in the presence and absence of a α7nAChR agonist (PHA-543613 hydrochloride) alone or after pre-exposure to a specific α7nAChR antagonist (α-bungarotoxin). Interleukin-8 (IL-8) expression was measured by ELISA and real-time PCR. Phosphorylation of the NF-κB p65 subunit was determined using an NF-κB p65 profiler assay and STAT-3 activation by STAT-3 in-cell ELISA. The release of ACh from oral keratinocytes in response to <i>P. gingivalis</i> lipopolysaccharide was determined using a GeneBLAzer M3 CHO-K1-blacell reporter assay.<p></p>
Results:
Expression of α7nAChR mRNA was elevated in diseased periodontal tissue. PHA-543613 hydrochloride inhibited <i>P. Gingivalis</i>-induced expression of IL-8 at the transcriptional level. This effect was abolished when cells were pre-exposed to a specific α7nAChR antagonist, α-bungarotoxin. PHA-543613 hydrochloride downregulated NF-κB signalling through reduced phosphorylation of the NF-κB p65-subunit. In addition, PHA-543613 hydrochloride promoted STAT-3 signalling by maintenance of phosphorylation. Furthermore, oral keratinocytes upregulated ACh release in response to <i>P. Gingivalis</i> lipopolysaccharide.<p></p>
Conclusion:
These data suggest that α7nAChR plays a role in regulating the innate immune responses of oral keratinocytes.<p></p>
Prevalence of childhood disability and the characteristics and circumstances of disabled children in the UK : secondary analysis of the Family Resources Survey
Background: Robust data on the prevalence of childhood disability and the circumstances and characteristics of
disabled children is crucial to understanding the relationship between impairment and social disadvantage. It is also
crucial for public policy development aimed at reducing the prevalence of childhood disability and providing
appropriate and timely service provision. This paper reports prevalence rates for childhood disability in the United
Kingdom (UK) and describes the social and household circumstances of disabled children, comparing these where
appropriate to those of non-disabled children.
Methods: Data were generated from secondary analysis of the Family Resources Survey, a national UK cross-sectional
survey, (2004/5) which had data on 16,012 children aged 0-18 years. Children were defined as disabled if they met the
Disability Discrimination Act (DDA) definition (1995 and 2005). Frequency distributions and cross-tabulations were run
to establish prevalence estimates, and describe the circumstances of disabled children. To establish the association
between individual social and material factors and childhood disability when other factors were controlled for, logistic
regression models were fitted on the dependent variable 'DDA defined disability'.
Results: 7.3% (CI 6.9, 7.7) of UK children were reported by as disabled according to the DDA definition. Patterns of
disability differed between sexes with boys having a higher rate overall and more likely than girls to experience
difficulties with physical coordination; memory, concentration and learning; communication. Disabled children lived in
different personal situations from their non-disabled counterparts, and were more likely to live with low-income,
deprivation, debt and poor housing. This was particularly the case for disabled children from black/minority ethnic/
mixed parentage groups and lone-parent households. Childhood disability was associated with lone parenthood and
parental disability and these associations persisted when social disadvantage was controlled for.
Conclusion: These analyses suggest that UK disabled children experience higher levels of poverty and personal and
social disadvantage than other children. Further research is required to establish accurate prevalence estimates of
childhood disability among different black and minority ethnic groups and to understand the associations between
childhood disability and lone parenthood and the higher rates of sibling and parental disability in households with
disabled children
Broad Line Region Physical Conditions along the Quasar Eigenvector 1 Sequence
[Abridged] We compare broad emission line profiles and estimate line ratios
for all major emission lines between Ly-alpha and H-beta in a sample of six
quasars. The sources were chosen with two criteria in mind: the existence of
high quality optical and UV spectra as well as the possibility to sample the
spectroscopic diversity in the 4D Eigenvector 1 context . In the latter sense
each source occupies a region (bin) in the FWHM(H-beta) vs. optical FeII
strength plane that is significantly different from the others. High S/N H-beta
emission line profiles are used as templates for modeling the other lines
(Ly-alpha, CIV 1549, HeII 1640, Al III 1860, Si III] 1892, and Mg II 2800). We
can adequately model all broad lines assuming the existence of three components
distinguished by blueshifted, unshifted and redshifted centroids (indicated as
blue, broad and very broad component respectively). The broad component (high
electron density, low ionization parameter; high column density) is present in
almost all type-1 quasars and therefore corresponds most closely to the
classical broad line emitting region (the reverberating component). The blue
component emission (lower electron density; high ionization; low column
density) arises in less optically thick gas; it is often thought to arise in an
accretion disk wind. The least understood component involves the very broad
component (high ionization and large column density). It is perhaps the most
distinguishing characteristic of quasars with FWHM H-beta > 4000 km/s that
belong to the so-called Population B of our 4DE1 space. Population A quasars
(FWHM H-beta < 4000 km/s) are dominated by broad component emission in H-beta
and blue component emission in CIV 1549 and other high ionization lines. 4DE1
appears to be the most useful current context for revealing and unifying
spectral diversity in type-1 quasars.Comment: 7 Tables, 5 Figures; accepted for publication in Monthly Notices of
the Royal Astronomical Societ
Multilateralizing Asian Regionalism
Motivated by the proliferation of free trade agreements (FTAs) in Asia over the last decade, this paper studies the challenges faced by the Asian "noodle bowl" - overlapping, multiple trade rules, regulations, and standards in Asia - in the process of regional and global trade integration. The paper first highlights the importance of trade and investment linkages among Asian economies that have formed Asian supply chains, called Factory Asia. It then considers ways and means of multilateralizing Asian trade regionalism by discussing the pros and cons of various approaches - such as the Association of Southeast Asian Nations (ASEAN)-centered regional trade agreements, including the Regional Comprehensive Economic Partnership agreement, and cross-regional FTAs, including the Trans-Pacific Partnership agreement and a future Asia-European Union FTA. The paper emphasizes the promising role of inclusive Asian regionalism and the need to move to global integration
Galaxy Zoo: dust and molecular gas in early-type galaxies with prominent dust lanes
We study dust and associated molecular gas in 352 nearby early-type galaxies
(ETGs) with prominent dust lanes. 65% of these `dusty ETGs' (D-ETGs) are
morphologically disturbed, suggesting a merger origin. This is consistent with
the D-ETGs residing in lower density environments compared to the controls
drawn from the general ETG population. 80% of D-ETGs inhabit the field
(compared to 60% of the controls) and <2% inhabit clusters (compared to 10% of
the controls). Compared to the controls, D-ETGs exhibit bluer UV-optical
colours (indicating enhanced star formation) and an AGN fraction that is more
than an order of magnitude greater (indicating higher incidence of nuclear
activity). The clumpy dust mass residing in large-scale features is estimated,
using the SDSS r-band images, to be 10^{4.5}-10^{6.5} MSun. A comparison to the
total (clumpy + diffuse) dust masses- calculated using the far-IR fluxes of 15%
of the D-ETGs that are detected by the IRAS- indicates that only ~20% of the
dust resides in these large-scale features. The dust masses are several times
larger than the maximum value expected from stellar mass loss, ruling out an
internal origin. The dust content shows no correlation with the blue
luminosity, indicating that it is not related to a galactic scale cooling flow.
No correlation is found with the age of the recent starburst, suggesting that
the dust is accreted directly in the merger rather than being produced in situ
by the triggered star formation. Using molecular gas-to-dust ratios of ETGs in
the literature we estimate that the median current and initial molecular gas
fraction are ~1.3% and ~4%, respectively. Recent work suggests that the merger
activity in nearby ETGs largely involves minor mergers (mass ratios between
1:10 and 1:4). If the IRAS-detected D-ETGs form via this channel, then the
original gas fractions of the accreted satellites are 20%-44%. [Abridged]Comment: 11 pages, 18 figures, 1 table, MNRAS (Accepted for publication- 2012
March 19
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