2,766 research outputs found
Review of Alaska Mental Health Statutes
This report identifies key statutory provisions that we recommend be amended, a description of our findings based on interviews with stakeholders, legislative history of the Alaska statutes, reviews of national best practices and, where applicable, information about emerging areas in national mental health law for Alaska to consider in creating new law. Our recommendations are based in large part on significant advances in law and medicine in the understanding and treatment of mental illness that have occurred in the years since Alaska last made significant and substantive reforms to its criminal and civil mental health statutes. It is important to note that proper implementation of many of the suggested reforms will require significant allocation of resources and development of infrastructure throughout the state and within local communities
Review of Alaska Mental Health Statutes
Review of Alaska Mental Health Statutes produced in 2016
Topical Application of Imiquimod as a Treatment for Chromoblastomycosis
Peer reviewedPublisher PD
A Multi-wavelength analysis of M81: insight on the nature of Arp's loop
Context: The optical ring like structure detected by Arp (1965) around M81
(commonly referenced as "Arp's loop") represents one of the most spectacular
feature observed in nearby galaxies. Arp's loop is commonly interpreted as a
tail resulting from the tidal interaction between M81 and M82. However, since
its discovery the nature of this feature has remained controversial. Aims: Our
primary purpose was to identify the sources of optical and infrared emission
observed in Arp's loop. Methods: The morphology of the Arp's loop has been
investigated with deep wide-field optical images. We also measured its colors
using IRAS and Spitzer-MIPS infrared images and compared them with those of the
disk of M81 and Galactic dust cirrus that fills the area where M81 is located.
Results: Optical images reveal that this peculiar object has a filamentary
structure characterized by many dust features overlapping M81's field. The
ratios of far-infrared fluxes and the estimated dust-to-gas ratios indicate the
infrared emission of Arp's loop is dominated by the contribution of cold dust
that is most likely from Galactic cirrus. Conclusions: The above results
suggest that the light observed at optical wavelengths is a combination of
emission from i) a few recent star forming regions located close to M81, where
both bright UV complexes and peaks in the HI distribution are found, ii) the
extended disk of M81 and iii) scattered light from the same Galactic cirrus
that is responsible for the bulk of the far infrared emission.Comment: 7 pages, 7 figures, accepted for publication by A&
Dextran and its potential use as tablet excipient
Dextrans are a class of carbohydrate polymers extensively applied in pharmaceutical applications, particularly as drug conjugate macromolecular carriers or drug delivery systems. These polysaccharides improve the stability of the therapeutics enabling also the control of their release, via either the parenteral and or oral routes. In the latter case, due to their gel forming ability they may have potential as hydrophilic matrix tablets for sustained drug release.
In this paper, we investigated the behaviour of different molecular weight (1, 40, 500 and 2300 kDa) dextrans as tabletting excipients. Powder particle size and hygroscopic studies have been reported, together with tabletability, tablet stability and tablet swelling. Moreover we use tramadol as model compound to evaluate the ability of dextrans to control drug dissolution. The results suggest that dextrans with lower molecular weights may be a promising excipient to be used as filler for immediate release tablets, due to their good tabletability and fast dissolution rate, while dextrans with higher molecular weights could be an efficient disintegrant due to their swelling ability
The GALEX Ultraviolet Atlas of Nearby Galaxies
We present images, integrated photometry, surface-brightness and color
profiles for a total of 1034 nearby galaxies recently observed by the GALEX
satellite in its far-ultraviolet (FUV; 1516A) and near-ultraviolet (NUV; 2267A)
bands. (...) This data set has been complemented with archival optical,
near-infrared, and far-infrared fluxes and colors. We find that the integrated
(FUV-K) color provides robust discrimination between elliptical and
spiral/irregular galaxies and also among spiral galaxies of different
sub-types. Elliptical galaxies with brighter K-band luminosities (i.e. more
massive) are redder in (NUV-K) color but bluer in (FUV-NUV) than less massive
ellipticals. In the case of the spiral/irregular galaxies our analysis shows
the presence of a relatively tight correlation between the (FUV-NUV) color and
the total infrared-to-UV ratio. The correlation found between (FUV-NUV) color
and K-band luminosity (with lower luminosity objects being bluer than more
luminous ones) can be explained as due to an increase in the dust content with
galaxy luminosity.
The images in this Atlas along with the profiles and integrated properties
are publicly available through a dedicated web page at
http://nedwww.ipac.caltech.edu/level5/GALEX_Atlas/Comment: 181 pages, 10 figures, accepted for publication in ApJS (abstract
abridged
Dust properties in M31.I.Basic properties and a discussion on age-dependent dust heating
Context. Spitzer Space Telescope observations and dust emission models are
used to discuss the distribution of dust and its characteristics in M31.
Together with GALEX FUV, NUV, and SDSS images we studied the age dependence of
the dust heating process. Methods.Spitzer IRAC/MIPS maps of M31 were matched
together and compared to dust emission models allowing to constrain the dust
mass, the intensity of the mean radiation field, the abundance of Polycyclic
Aromatic Hydrocarbons (PAH) particles. The total infrared emission (TIR) was
analyzed in function of UV and Optical colors and compared to predictions of
models which consider the age-dependent dust heating. Results. We demonstrate
that cold-dust component emission dominates the infrared spectral energy
distribution of M31. The mean intensity of the radiation field heating the dust
is low (typically U<2, where U=1 is the value in the solar surrounding). Due to
the lack of submillimetric measurements the dust mass (M_{dust}) is only weakly
constrained by the infrared spectrum. We show that across the spiral-ring
structure of M31 a fraction >3% of the total dust mass is in PAHs. UV and
optical colors are correlated to (TIR/FUV) ratios in \sim 670 pc-sized regions
overall the disk of M31, although deviating from the IRX-beta relationship for
starburst galaxies. We derived that in 83% of the regions analyzed across the
10kpc ring more than 50% of the energy absorbed by the dust is rediated at
\lambda > 4000 \AA and that dust in M31 appears mainly heated by populations a
few Gyr old even across the star-forming ring. The attenuation is varying
radially peaking near 10kpc and decreasing faster in the inner regions of M31
than in the outer regions. We finally derived the attenuation map of M31 at
6"/px resolution (\sim 100 pc/px along the plane of M31).[abridged]Comment: 21 pages, 18 figures, accepted for publication in A&A. Only low
resolution images included, full resolution images will be avaiable in the
journal electronic version. Fig.14 and Fig.17 will be avaiable via CD
The Spitzer Local Volume Legacy: Survey Description and Infrared Photometry
The survey description and the near-, mid-, and far-infrared flux properties
are presented for the 258 galaxies in the Local Volume Legacy (LVL). LVL is a
Spitzer Space Telescope legacy program that surveys the local universe out to
11 Mpc, built upon a foundation of ultraviolet, H-alpha, and HST imaging from
11HUGS (11 Mpc H-alpha and Ultraviolet Galaxy Survey) and ANGST (ACS Nearby
Galaxy Survey Treasury). LVL covers an unbiased, representative, and
statistically robust sample of nearby star-forming galaxies, exploiting the
highest extragalactic spatial resolution achievable with Spitzer. As a result
of its approximately volume-limited nature, LVL augments previous Spitzer
observations of present-day galaxies with improved sampling of the
low-luminosity galaxy population. The collection of LVL galaxies shows a large
spread in mid-infrared colors, likely due to the conspicuous deficiency of 8um
PAH emission from low-metallicity, low-luminosity galaxies. Conversely, the
far-infrared emission tightly tracks the total infrared emission, with a
dispersion in their flux ratio of only 0.1 dex. In terms of the relation
between infrared-to-ultraviolet ratio and ultraviolet spectral slope, the LVL
sample shows redder colors and/or lower infrared-to-ultraviolet ratios than
starburst galaxies, suggesting that reprocessing by dust is less important in
the lower mass systems that dominate the LVL sample. Comparisons with
theoretical models suggest that the amplitude of deviations from the relation
found for starburst galaxies correlates with the age of the stellar populations
that dominate the ultraviolet/optical luminosities.Comment: Accepted for publication in ApJ; Figures 1,8,9 provided as jpeg
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