14,193 research outputs found

    Estrogenic activity, race/ethnicity, and Indigenous American ancestry among San Francisco Bay Area women.

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    Estrogens play a significant role in breast cancer development and are not only produced endogenously, but are also mimicked by estrogen-like compounds from environmental exposures. We evaluated associations between estrogenic (E) activity, demographic factors and breast cancer risk factors in Non-Latina Black (NLB), Non-Latina White (NLW), and Latina women. We examined the association between E activity and Indigenous American (IA) ancestry in Latina women. Total E activity was measured with a bioassay in plasma samples of 503 women who served as controls in the San Francisco Bay Area Breast Cancer Study. In the univariate model that included all women with race/ethnicity as the independent predictor, Latinas had 13% lower E activity (p = 0.239) and NLBs had 35% higher activity (p = 0.04) compared to NLWs. In the multivariable model that adjusted for demographic factors, Latinas continued to show lower E activity levels (26%, p = 0.026), but the difference between NLBs and NLWs was no longer statistically significant (p = 0.431). An inverse association was observed between E activity and IA ancestry among Latina women (50% lower in 0% vs. 100% European ancestry, p = 0.027) consistent with our previously reported association between IA ancestry and breast cancer risk. These findings suggest that endogenous estrogens and exogenous estrogen-like compounds that act on the estrogen receptor and modulate E activity may partially explain racial/ethnic differences in breast cancer risk

    Manipulating the perceived shape and color of a virtual limb can modulate pain responses

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    Changes in body representation may affect pain perception. The effect of a distorted body image, such as the telescoping effect in amputee patients, on pain perception, is unclear. This study aimed to investigate whether distorting an embodied virtual arm in virtual reality (simulating the telescoping effect in amputees) modulated pain perception and anticipatory responses to pain in healthy participants. Twenty-seven right-handed participants were immersed in virtual reality and the virtual arm was shown with three different levels of distortion with a virtual threatening stimulus either approaching or contacting the virtual hand. We evaluated pain/discomfort ratings, ownership, and skin conductance responses (SCRs) after each condition. Viewing a distorted virtual arm enhances the SCR to a threatening event with respect to viewing a normal control arm, but when viewing a reddened-distorted virtual arm, SCR was comparatively reduced in response to the threat. There was a positive relationship between the level of ownership over the distorted and reddened-distorted virtual arms with the level of pain/discomfort, but not in the normal control arm. Contact with the threatening stimulus significantly enhances SCR and pain/discomfort, while reduced SCR and pain/discomfort were seen in the simulated-contact condition. These results provide further evidence of a bi-directional link between body image and pain perception

    An Ecosystem Approach to the Role of Fish Farming in Coastal Areas

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    Coastal ecosystems put up most of the impacts from human activities in the sea. Generally, assessment based on a unispecific ecological group and/or habitat reflects only a fraction of what is happening in the ecosystem, and usually it is biased by the spatial and temporal variability at small scales. This is more evident when several human activities co-exist in the same area and interact synergically among them and with the natural structure and dynamics of the ecosystem. An ecosystemic assessment can combine several ecological groups, habitats, processes and/or activities, and offer a more holistic picture about the structure and dynamics of the considered coastal area.This study was partially funded by Spanish Ministry of Science Grant (Project FATFISH CTM2009-14362-C02-01). JTBS thanks to Conselleria d'Educació, Generalitat Valenciana, for financing the visit to La Paz during 2012. FAS thanks support to visit the University of Alicante during 2013

    Stomatal and non-stomatal limitations on leaf carbon assimilation in beech (Fagus sylvatica L.) seedlings enduring moderate water stress under natural conditions

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    Seasonal variation and the differential effect of drought on photosynthetic parameters involved in carbon assimilation in forest species have been poorly studied under natural conditions. Limitations to diffusion and biochemical factors affecting leaf carbon uptake were analyzed in young beech seedlings (Fagus sylvatica L.) growing in natural gaps of a beech-wood at the southern limit of the species. Half of the seedling received periodic watering in addition to natural rainfall to reduce the severity of the summer drought which is typical in the area. Plant water status was evaluated by measuring predawn water potential. Basic biochemical parameters were inferred from photosynthesis-CO2 curves (A-Cc) under saturating light and chlorophyll fluorescence. The curves were established on three dates during the summer months Main variables studied included: stomatal and mesophyll conductance to CO2 (gs and gm respectively), maximum velocity of carboxylation (Vcmax) and maximum electron transport capacity (Jmax). The gm was estimated by two methodologies: the curve-fitting and J constant methods. Seedlings withstood a moderate water stress as the leaf predawn water potential (Ψpd) measured during the study was within the range –0.2 to –0.5 MPa. A mild drought caused gs and gm to decrease only slightly in response to Ψpd. However both diffusional parameters explained most of the limitations to CO2 uptake. Furthermore, non-stomatal limitations were also important limiting net photosynthesis as water stress increased. In addition, it should be highlighted that the biochemical limitations, prompted by Vcmax and Jmax, were related mainly to ontogenic factors, without any clear relationship with drought under the moderate water stress experienced by beech seedlings through the study. The results may help to further understand of the functional mechanisms influencing carbon fixation capacity of beech seedlings. This capacity may influence the total carbon balance of beech seedlings, and feed forward to their growth and survival under drought-prone environments such as those in the south of Europe.Peer reviewe

    Boyeria Irene (Fonscolombe, 1838) y Cordulegaster Boltonii (Donovan, 1807) (Odonata): Dos estrategias en cuanto a sustratos de emergencia de larvas en un mismo hábitat.

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    Se presentan datos sobre emergencia de Cordulegaster boltonii y Boyeria irene en un río de montaña del centro de España (altitud 1200 m s.n.m.) donde coexisten ambas especies, basados en la recogida semanal de exuvias. Boyeria irene comenzó a emerger 28 días más tarde que C. boltonii. Los sustratos usados por las larvas de ambas especies para emerger se solaparon ampliamente, aunque C. boltonii utilizó significativamente más árboles. Con respecto a otras zonas geográficas, las dos especies han modificado su estrategia, retrasando el inicio del periodo de emergencia. Se discute la importancia de las condiciones ambientales (sobre todo temperatura) en este hecho

    Seedlings from marginal and core populations of European beech (Fagus sylvatica L.) respond differently to imposed drought and shade

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    Warming temperatures and altered precipitation patterns threaten plant populations worldwide. European beech (Fagus sylvatica) is a species that expresses both high phenotypic plasticity and local adaptation among populations. Beech seedlings’ susceptibility to prolonged drought may be dictated by their immediate light environment. We tested whether seedlings of four beech provenances, from contrasting edaphoclimatic environments, expressed differences in trait responses to imposed water stress under sun and shade treatments. Populations from the southern range margin were expected to display greater water-stress tolerance and core populations’ faster growth rates in the absence of abiotic limitations. Both high light and water stress induced differences in trait responses among provenances, but traits that failed to respond to our experimental treatments likewise did not segregate at the provenance level. Hence, those traits responding to light, e.g., increasing leaf flavonol index and leaf mass area, also tended to differ among rovenances. Similarly, there was evidence of local adaptation among provenances in traits, like midday leaf water potential, responding to water stress. Exceptionally, there was a three way interaction water- × -light- × -provenance for stomatal conductance which converged among provenances under water stress. Leaf chlorophyll content also varied both with light and water in a provenance-specific manner. We found core provenances’ growth traits to outperform others under favourable onditions, whereas southern and high-elevation populations displayed traits adapted to tolerate high irradiance. Only stomatal conductance produced a complementary interactive response between light- × -water across provenances, whereas other traits responded less to combined water stress and high irradiance than to either treatment alone.Peer reviewe

    Tools for analyzing parallel I/O

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    Parallel application I/O performance often does not meet user expectations. Additionally, slight access pattern modifications may lead to significant changes in performance due to complex interactions between hardware and software. These issues call for sophisticated tools to capture, analyze, understand, and tune application I/O. In this paper, we highlight advances in monitoring tools to help address these issues. We also describe best practices, identify issues in measure- ment and analysis, and provide practical approaches to translate parallel I/O analysis into actionable outcomes for users, facility operators, and researchers

    Exploring the adoption of precision agricultural technologies: a cross regional study of EU farmers

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    Precision agricultural technologies (PATs) allow more detailed management of in-field variability. Policy and advisory communities have championed PATs as a route to preserving natural capital whilst increasing productivity from agricultural land. A range of PATs are currently available for the agricultural producer but uptake varies by the type of technology and region. Whereas most studies on uptake have focused on US or Australia we empirically examine uptake of machine guidance (MG) and variable rate nitrogen technologies (VRNT) within European farming systems. Using primary information from 971 arable crop growers across five countries: Belgium, Germany, Greece, the Netherlands and the UK, a multilevel random intercept regression estimated a) the differences between adoption and non-adoption and b) the differences between VRNT and MG adoption. We find, aside from size and income differences, which reflect the economic cost barrier to adoption, an attitudinal difference, in terms of optimism towards the technology's economic return leading to more probability of uptake. Moreover innovative and information seeking behaviour also proved significant when upgrading from machine guidance to variable rate technologies. Subsidy and taxation were considered positive drivers of uptake within the community. However, results suggest that more indirect interventions, such as informational support to counteract industry bias, and demonstration to prove the viability of economic return may be effective at meeting land manager and policy expectations towards PATs

    Motivations for Food Consumption during Specific Eating Occasions in Turkey

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    Citation: Chambers, D., Phan, U. T. X., Chanadang, S., Maughan, C., Sanchez, K., Di Donfrancesco, B., . . . Esen, E. (2016). Motivations for Food Consumption during Specific Eating Occasions in Turkey. Foods, 5(2), 14. doi:10.3390/foods5020039Several studies in different countries have been conducted to investigate factors affecting food choices. The objective of this study was to understand the motivations of specific food and beverage choices for different eating occasions in a typical diet of the Turkish people. A convenience sample of 141 respondents from seven different geographical regions in Turkey completed an online survey questionnaire that included questions about demographic information and details about their latest eating occasion. Respondents reported all of their motivations for choosing each food/beverage item reported for that specific eating occasion. Results indicated that different motivations played different roles in food choices of people in Turkey. Liking was a key characteristic for all eating occasions, but key natural concerns were even more important at breakfast, and need and hunger were more important for a mid-afternoon snack. Lunch involved additional motivations such as Sociability, Variety Seeking, and Social Norms. In addition to Liking, choices of different food groups were also driven by other motivations such as Habits, Convenience, Need and Hunger, Natural Concerns, and Health. This study helped better understand the current dietary patterns of Turkish people as well as the motives underlying their choices of foods and beverages for different meals and snacks. These findings could be useful for dietary campaigns that aim to improve eating behaviors in Turkey

    Stomatal and non-stomatal limitations on leaf carbon assimilation in beech (Fagus sylvatica L.) seedlings under natural conditions

    Get PDF
    Limitations to diffusion and biochemical factors affecting leaf carbon uptake were analyzed in young beech seedlings (Fagus sylvtica L.) growing in natural gaps of a beech-wood at the southern limit of the species. Half of the seedlings received periodic watering in addition to natural rainfall to reduce the severity of the summer drought. Plant water status was evaluated by measuring predawn water potential. Basic biochemical parameters were inferred from chlorophyll fluorescence and photosynthesis-CO2 curves (A-Cc) under saturating light. The curves were established on three dates during the summer months. The main variables studied included: stomatal and mesophyll conductance to CO2 (gs and gm respectively), maximum velocity of carboxylation (Vcmax) and maximum electron transport capacity (Jmax). The gm was estimated by two methodologies: the curve-fitting and J constant methods. Seedlings withstood moderate water stress, as the leaf predawn water potential (Ψpd) measured during the study was within the range –0.2 to –0.5 MPa. Mild drought caused gs and gm to decrease only slightly in response to Ψpd. However both diffusional parameters explained most of the limitations to CO2 uptake. In addition, it should be highlighted that biochemical limitations, prompted by Vcmax and Jmax, were related mainly to ontogenic factors, without any clear relationship with drought under the moderate water stress experienced by beech seedlings through the study. The results may help to further understanding of the functional mechanisms influencing the carbon fixation capacity of beech seedlings under natural conditions.Peer reviewe
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