6,731 research outputs found
IS CONTRAST-ASSOCIATED ACUTE KIDNEY INJURY (CA-AKI) ASSOCIATED TO THE TYPE OF HOSPITAL AND ICU? PRELIMINAY RESULTS OF THE NEFROCON STUDY
Carbon-fiber tips for scanning probe microscopes and molecular electronics experiments
We fabricate and characterize carbon-fiber tips for their use in combined
scanning tunneling and force microscopy based on piezoelectric quartz tuning
fork force sensors. An electrochemical fabrication procedure to etch the tips
is used to yield reproducible sub-100-nm apex. We also study electron transport
through single-molecule junctions formed by a single octanethiol molecule
bonded by the thiol anchoring group to a gold electrode and linked to a carbon
tip by the methyl group. We observe the presence of conductance plateaus during
the stretching of the molecular bridge, which is the signature of the formation
of a molecular junction.Comment: Conference Proceeding (Trends in NanoTechnology 2011, Tenerife
SPAIN); Nanoscale Research Letters, (2012) 7:25
Prácticas de autocuidado en adultos mayores: un estudio cualitativo en población mexicana
Background: Older adults perform self-care activities based on common knowledge, which should be valued by the nursing team. Objectives: To describe and analyze the self-care behaviors of older adults in a Mexican population. Methodology: Qualitative ethnographic study, using Leininger’s qualitative research method. Results: Seventeen older adults were interviewed. Te analysis resulted in 4 explanatory patterns: 1) I keep my peace of mind through what I think, feel, and believe; 2) I watch my diet and pay attention not only to what I eat but also how I eat it; 3) Staying busy is what keeps me going; 4) and Seeking help and helping myself. Te following risk behaviors were identifed: Postponing medical care; Self-medication; and Food-related beliefs. Conclusion: Identifying older adults’ reported behaviors would contribute to the planning of culturally-sensitive nursing interventions.Marco contextual: Los adultos mayores realizan prácticas de autocuidado con base en sus saberes populares, estas de- ben ser valoradas por el personal de enfermería. Objetivos: Describir y analizar las prácticas de autocuidado que llevan a cabo adultos mayores de una población mexicana. Metodología: Investigación cualitativa etnográfica, en la que se utilizó el método de análisis cualitativo de Leininger. Resultados: Se entrevistó a 17 adultos mayores. El análisis originó 4 patrones explicativos: 1) Conservo mi tranquilidad a través de lo que pienso, siento y creo; 2) Cuido mi alimentación porque no solo es lo que se come, sino cómo se come; 3) Mantenerme ocupado es lo que me tiene en pie; 4) Pidiendo ayuda y ayudándose uno mismo. Las prácticas de riesgo son posponer la atención médica, automedicarse y las creencias en la alimentación. Conclusión: La identificación de las prácticas expresadas por los adultos mayores aportaría una plusvalía en la planificación de las intervenciones de enfermería en el ámbito de los cuidados culturalmente sensibles
Chemical Evolution of CoCrMo Wear Particles: An in Situ Characterization Study
The unexpected high failure rates of CoCrMo hip implants are associated with the release of a large number of inflammatory wear particles. CoCrMo is nominally a stable material; however, previous chemical speciation studies on CoCrMo wear particles obtained from periprosthetic tissue revealed only trace amounts of Co remaining despite Co being the major component of the alloy. The unexpected high levels of Co dissolution in vivo raised significant clinical concerns particularly related to the Cr speciation in the dissolution process. At high electrochemical potentials, the alloy's Cr-rich passive film breaks down (transpassive polarization), facilitating alloy dissolution. The potential release of the carcinogenic Cr(VI) species in vivo has been a subject of debate. While the large-scale Co dissolution observed on in vivo produced particles could indicate a highly oxidizing in vivo environment, Cr(VI) species were not previously detected in periprosthetic tissue samples (except in the specific case of post-mortem tissue of diabetic patients). However, Cr(VI) is likely to be an unstable (transient) species in biological environments, and studies on periprosthetic tissue do not provide information about intermediate reaction products or the exposure history of the wear particles. Here, an in situ spectromicroscopy approach was developed, utilizing the high chemical resolution of synchrotron radiation, to study CoCrMo reactivity as a function of time and oxidizing conditions. The results reveal limited Co dissolution from CoCrMo particles, which increases dramatically at a critical electrochemical potential. Furthermore, in situ XAS detected only Cr(III) dissolution, even at potentials where Cr(VI) is known to be produced, suggesting that Cr(VI) species are extremely transient in simulated biological environments where the oxidation zone is small
Ruling out four-neutrino oscillation interpretations of the LSND anomaly?
Prompted by recent solar and atmospheric data, we re-analyze the
four-neutrino description of current global neutrino oscillation data,
including the LSND evidence for oscillations. The higher degree of rejection
for non-active solar and atmospheric oscillation solutions implied by the SNO
neutral current result as well as by the latest 1489-day Super-K atmospheric
neutrino data allows us to rule out (2+2) oscillation schemes proposed to
reconcile LSND with the rest of current neutrino oscillation data. Using an
improved goodness of fit (gof) method especially sensitive to the combination
of data sets we obtain a gof of only 1.6 times 10^{-6} for (2+2) schemes.
Further, we re-evaluate the status of (3+1) oscillations using two different
analyses of the LSND data sample. We find that also (3+1) schemes are strongly
disfavoured by the data. Depending on the LSND analysis we obtain a gof of 5.6
times 10^{-3} or 7.6 times 10^{-5}. This leads to the conclusion that all
four-neutrino descriptions of the LSND anomaly, both in (2+2) as well as (3+1)
realizations, are highly disfavoured. Our analysis brings the LSND hint to a
more puzzling status.Comment: 21 pages, 7 figure
Cornering (3+1) sterile neutrino schemes
Using the most recent atmospheric neutrino data, as well as short-baseline,
long-baseline and tritium -decay data we show that the joint
interpretation of the LSND, solar and atmospheric neutrino anomalies in (3+1)
sterile neutrino schemes is severely disfavored, in contrast to the
theoretically favored (2+2) schemes.Comment: 14 pages, 4 figures, v3: extended tritium decay analysis, small
corrections in Fig. 2 and Eq.(4), version accepted for publication in Phys.
Lett.
ZnO Nanomaterials and Ionic Zn Partition within Wastewater Sludge Investigated by Isotopic Labeling
The increasing commercial use of engineered zinc oxide nanomaterials necessitates a thorough understanding of their behavior following their release into wastewater. Herein, the fates of zinc oxide nanoparticles (ZnO NPs) and ionic Zn in a real primary sludge collected from a municipal wastewater system are studied via stable isotope tracing at an environmentally relevant spiking concentration of 15.2 µg g−1. Due to rapid dissolution, nanoparticulate ZnO does not impart particle-specific effects, and the Zn ions from NP dissolution and ionic Zn display indistinguishable behavior as they partition equally between the solid, liquid, and ultrafiltrate phases of the sludge over a 4-h incubation period. This work provides important constraints on the behavior of engineered ZnO nanomaterials in primary sludge—the first barrier in a wastewater treatment plant—at low, realistic concentrations. As the calculated solid–liquid partition coefficients are significantly lower than those reported in prior studies that employ unreasonably high spiking concentrations, this work highlights the importance of using low, environmentally relevant doses of engineered nanomaterials in experiments to obtain accurate risk assessments
Active-active and active-sterile neutrino oscillation solutions to the atmospheric neutrino anomaly
We perform a fit to the full data set corresponding to 33.3 kt-yr of data of
the Super-Kamiokande experiment as well as to all other experiments in order to
compare the two most likely solutions to the atmospheric neutrino anomaly in
terms of oscillations in the and
channels. Using state-of-the-art atmospheric neutrino fluxes we have determined
the allowed regions of oscillation parameters for both channels. We find that
the values for the active-sterile oscillations (both for positive
and negative ) are higher than for the case,
and that the increased Super-Kamiokande sample slightly favours oscillations over oscillations into a sterile species ,
, and disfavours . We also give the
zenith angle distributions predicted for the best fit points in each of the
possible oscillation channels. Finally we compare our determinations of the
atmospheric neutrino oscillation parameters with the expected sensitivities of
future long-baseline experiments K2K, MINOS, ICARUS, OPERA and NOE.Comment: Updated to 535 days of Super-Kamiokande and corresponding
modifications in the discussion and figures. Some References adde
Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors
Hypertension, diabetes and obesity are cardiovascular risk factors closely associated to the development of renal and cardiovascular target organ damage. VAV2 and VAV3, members of the VAV family proto-oncogenes, are guanosine nucleotide exchange factors for the Rho and Rac GTPase family, which is related with cardiovascular homeostasis. We have analyzed the relationship between the presence of VAV2 rs602990 and VAV3 rs7528153 polymorphisms with cardiovascular risk factors and target organ damage (heart, vessels and kidney) in 411 subjects. Our results show that being carrier of the T allele in VAV2 rs602990 polymorphism is associated with an increased risk of obesity, reduced levels of ankle-brachial index and diastolic blood pressure and reduced retinal artery caliber. In addition, being carrier of T allele is associated with increased risk of target organ damage in males. On the other hand, being carrier of the T allele in VAV3 rs7528153 polymorphism is associated with a decreased susceptibility of developing a pathologic state composed by the presence of hypertension, diabetes, obesity or cardiovascular damage, and with an increased risk of developing altered basal glycaemia. This is the first report showing an association between VAV2 and VAV3 polymorphisms with cardiovascular risk factors and target organ damage
- …