Oral health inequalities and the corporate determinants of health: a commentary

Empirical research critically examining the role of the corporate determinants of health has gained traction in the past few years. Many of these reports have received strong, sometimes litigious, backlash from the corporations exposed. The aim of this paper is to provide a critical commentary on existing literature, policies, procedures and observations of issues, especially regarding the use of the corporate determinants of health as a research construct, in the persistence and flourishing of oral health inequalities at a global level. We discuss theoretical frameworks that underpin the power constructs of the corporate determinants of health, including Lukes “three faces of power” theory. This theory posits that power is exercised in three ways: through decision-making, through non-decision-making and ideologically. We will demonstrate, using examples of corporate determinants of health and oral health inequalities from several countries, how intervening at key leverage points is a crucial strategy for improving oral health inequalities at a global level

Children’s rights in their oral health care: How responsive are oral health professionals to children’s rights

Research on children’s rights in oral health care is lacking, and this study aims to partially fill this gap. In 2015, we conducted research in one region of New Zealand using video methods to explore the rights of 22 children during a specific oral health treatment, the placement of stainless steel crowns. Our findings show that many children did not receive a professional standard of care, there were gaps in the delivery and standard of care, and there were numerous examples of children’s rights’ violations. At the same time, however, some of the children’s dental practitioners’ (CDPs) actions may have been acceptable practice within the profession if children’s rights have not yet fully been embedded into the practice of oral health care workers. We conclude with a discussion of the implications of our findings and suggestions for a more rights based standard of oral health care

Final State Interactions in Hypernuclear Decay

We present an update of the One-Meson-Exchange (OME) results for the weak decay of s- and p-shell hypernuclei (Ref. Phys. Rev. C {\bf 56}, 339 (1997)), paying special attention to the role played by final state interactions between the emitted nucleons. The present study also corrects for a mistake in the inclusion of the $K$ and $K^*$ exchange mechanisms, which substantially increases the ratio of neutron-induced to proton-induced transitions, $\Gamma_n/\Gamma_p$. With the most up-to-date model ingredients, we find that the OME approach is able to describe very satisfactorily most of the measured observables, including the ratio $\Gamma_n/\Gamma_p$.Comment: 20 pages, 2 eps figure

Overview of the New Horizons Science Payload

The New Horizons mission was launched on 2006 January 19, and the spacecraft is heading for a flyby encounter with the Pluto system in the summer of 2015. The challenges associated with sending a spacecraft to Pluto in less than 10 years and performing an ambitious suite of scientific investigations at such large heliocentric distances (> 32 AU) are formidable and required the development of lightweight, low power, and highly sensitive instruments. This paper provides an overview of the New Horizons science payload, which is comprised of seven instruments. Alice provides spatially resolved ultraviolet spectroscopy. The Ralph instrument has two components: the Multicolor Visible Imaging Camera (MVIC), which performs panchromatic and color imaging, and the Linear Etalon Imaging Spectral Array (LEISA), which provides near-infrared spectroscopic mapping capabilities. The Radio Experiment (REX) is a component of the New Horizons telecommunications system that provides both occultation and radiometry capabilities. The Long Range Reconnaissance Imager (LORRI) provides high sensitivity, high spatial resolution optical imaging capabilities. The Solar Wind at Pluto (SWAP) instrument measures the density and speed of solar wind particles. The Pluto Energetic Particle Spectrometer Science Investigation (PEPSSI) measures energetic protons and CNO ions. The Venetia Burney Student Dust Counter (VB-SDC) is used to record dust particle impacts during the cruise phases of the mission.Comment: 17 pages, 4 figures, 1 table; To appear in a special volume of Space Science Reviews on the New Horizons missio

Structural Determinants and Children's Oral Health: A Cross-National Study

Much research on children's oral health has focused on proximal determinants at the expense of distal (upstream) factors. Yet, such upstream factors-the so-called structural determinants of health-play a crucial role. Children's lives, and in turn their health, are shaped by politics, economic forces, and social and public policies. The aim of this study was to examine the relationship between children's clinical (number of decayed, missing, and filled teeth) and self-reported oral health (oral health-related quality of life) and 4 key structural determinants (governance, macroeconomic policy, public policy, and social policy) as outlined in the World Health Organization's Commission for Social Determinants of Health framework. Secondary data analyses were carried out using subnational epidemiological samples of 8- to 15-y-olds in 11 countries ( N = 6,648): Australia (372), New Zealand (three samples; 352, 202, 429), Brunei (423), Cambodia (423), Hong Kong (542), Malaysia (439), Thailand (261, 506), United Kingdom (88, 374), Germany (1498), Mexico (335), and Brazil (404). The results indicated that the type of political regime, amount of governance (e.g., rule of law, accountability), gross domestic product per capita, employment ratio, income inequality, type of welfare regime, human development index, government expenditure on health, and out-of-pocket (private) health expenditure by citizens were all associated with children's oral health. The structural determinants accounted for between 5% and 21% of the variance in children's oral health quality-of-life scores. These findings bring attention to the upstream or structural determinants as an understudied area but one that could reap huge rewards for public health dentistry research and the oral health inequalities policy agenda

Parity-Violating Interaction Effects I: the Longitudinal Asymmetry in pp Elastic Scattering

The proton-proton parity-violating longitudinal asymmetry is calculated in the lab-energy range 0--350 MeV, using a number of different, latest-generation strong-interaction potentials--Argonne V18, Bonn-2000, and Nijmegen-I--in combination with a weak-interaction potential consisting of rho- and omega-meson exchanges--the model known as DDH. The complete scattering problem in the presence of parity-conserving, including Coulomb, and parity-violating potentials is solved in both configuration- and momentum-space. The predicted parity-violating asymmetries are found to be only weakly dependent upon the input strong-interaction potential adopted in the calculation. Values for the rho- and omega-meson weak coupling constants $h^{pp}_\rho$ and $h^{pp}_\omega$ are determined by reproducing the measured asymmetries at 13.6 MeV, 45 MeV, and 221 MeV.Comment: 24 pages, 8 figures, submitted to Physical Review

B-cell dysregulation in Crohn's disease is partially restored with infliximab therapy

Background: B-cell depletion can improve a variety of chronic inflammatory diseases, but does not appear beneficial for patients with Crohn's disease. Objective: To elucidate the involvement of B cells in Crohn's disease, we here performed an 'in depth' analysis of intestinal and blood B-cells in this chronic inflammatory disease. Methods: Patients with Crohn's disease were recruited to study B-cell infiltrates in intestinal biopsies (n = 5), serum immunoglobulin levels and the phenotype and molecular characteristics of blood B-cell subsets (n = 21). The effects of infliximab treatment were studied in 9 patients. Results: Granulomatous tissue showed infiltrates of B lymphocytes rather than Ig-secreting plasma cells. Circulating transitional B cells and CD21low B cells were elevated. IgM memory B cells were reduced and natural effector cells showed decreased replication histories and somatic hypermutation (SHM) levels. In contrast, IgG and IgA memory B cells were normally present and their Ig gene transcripts carried increased SHM levels. The numbers of transitional and natural effector cells were normal in patients who responded clinically well to infliximab. Conclusions: B cells in patients with Crohn's disease showed signs of chronic stimulation with localization to granulomatous tissue and increased molecular maturation of IgA and IgG. Therapy with TNFα-blockers restored the defect in IgM memory B-cell generation and normalized transitional B-cell levels, making these subsets candidate markers for treatment monitoring. Together, these results suggest a chronic, aberrant B-cell response in patients with Crohn's disease, which could be targeted with new therapeutics that specifically regulate B-cell function

Weak Decay of Lambda Hypernuclei

In this review we discuss the present status of strange nuclear physics, with special attention to the weak decay of Lambda hypernuclei. The models proposed for the evaluation of the Lambda decay widths are summarized and their results are compared with the data. Despite the recent intensive investigations, the main open problem remains a sound theoretical interpretation of the large experimental values of the ratio G_n/G_p. Although recent works offer a step forward in the solution of the puzzle, further efforts must be invested in order to understand the detailed dynamics of the non-mesonic decay. Even if, by means of single nucleon spectra measurements, the error bars on G_n/G_p have been considerably reduced very recently at KEK, a clean extraction of G_n/G_p is needed. What is missing at present, but planned for the next future, are measurements of 1) nucleon energy spectra in double coincidence and 2) nucleon angular correlations: such observations allow to disentangle the nucleons produced in one- and two-body induced decays and lead to a direct determination of G_n/G_p. For the asymmetric non-mesonic decay of polarized hypernuclei the situation is even more puzzling. Indeed, strong inconsistencies appear already among data. A recent experiment obtained a positive intrinsic Lambda asymmetry parameter, a_{Lambda}, for 5_{Lambda}He. This is in complete disagreement with a previous measurement, which obtained a large and negative a_{Lambda} for p-shell hypernuclei, and with theory, which predicts a negative value moderately dependent on nuclear structure effects. Also in this case, improved experiments establishing with certainty the sign and magnitude of a_{Lambda} for s- and p-shell hypernuclei will provide a guidance for a deeper understanding of hypernuclear dynamics and decay mechanisms.Comment: 129 pages, 21 figures, Submitted to Phys. Rep

Unsupervised crosslingual adaptation of tokenisers for spoken language recognition

Phone tokenisers are used in spoken language recognition (SLR) to obtain elementary phonetic information. We present a study on the use of deep neural network tokenisers. Unsupervised crosslingual adaptation was performed to adapt the baseline tokeniser trained on English conversational telephone speech data to different languages. Two training and adaptation approaches, namely cross-entropy adaptation and state-level minimum Bayes risk adaptation, were tested in a bottleneck i-vector and a phonotactic SLR system. The SLR systems using the tokenisers adapted to different languages were combined using score fusion, giving 7-18% reduction in minimum detection cost function (minDCF) compared with the baseline configurations without adapted tokenisers. Analysis of results showed that the ensemble tokenisers gave diverse representation of phonemes, thus bringing complementary effects when SLR systems with different tokenisers were combined. SLR performance was also shown to be related to the quality of the adapted tokenisers

Unsupervised crosslingual adaptation of tokenisers for spoken language recognition

Phone tokenisers are used in spoken language recognition (SLR) to obtain elementary phonetic information. We present a study on the use of deep neural network tokenisers. Unsupervised crosslingual adaptation was performed to adapt the baseline tokeniser trained on English conversational telephone speech data to different languages. Two training and adaptation approaches, namely cross-entropy adaptation and state-level minimum Bayes risk adaptation, were tested in a bottleneck i-vector and a phonotactic SLR system. The SLR systems using the tokenisers adapted to different languages were combined using score fusion, giving 7-18% reduction in minimum detection cost function (minDCF) compared with the baseline configurations without adapted tokenisers. Analysis of results showed that the ensemble tokenisers gave diverse representation of phonemes, thus bringing complementary effects when SLR systems with different tokenisers were combined. SLR performance was also shown to be related to the quality of the adapted tokenisers