Micro-beam and pulsed laser beam techniques for the micro-fabrication of diamond surface and bulk structures

Micro-fabrication in diamond is involved in a wide set of emerging technologies, exploiting the exceptional characteristics of diamond for application in bio-physics, photonics, radiation detection. Micro ion-beam irradiation and pulsed laser irradiation are complementary techniques, which permit the implementation of complex geometries, by modification and functionalization of surface and/or bulk material, modifying the optical, electrical and mechanical characteristics of the material. In this article we summarize the work done in Florence (Italy) concerning ion beam and pulsed laser beam micro-fabrication in diamond.Comment: 14 pages, 5 figure

Usefulness of panoramic 344°-viewing in Crohn's disease capsule endoscopy : a proof of concept pilot study with the novel PillCam™ Crohn's system

Background: A new capsule endoscopy (CE) system featuring two advanced optics for 344\ub0-viewing and a prolonged operative time has been recently developed for Crohn's disease (CD) patients. Hence, we evaluated, for the first time, the performance of this novel CE and the add-on value of the 344\ub0-viewing in a multi-center real-life setting. Methods: Consecutive patients with suspected or established CD received the PillCam\u2122 Crohn's System as supplementary diagnostic work-up focused on the small-bowel between June 2017 and June 2018. Technical and clinical data, including the panenteric CE diagnostic yield, the Lewis score and the impact of small-bowel findings on clinical management during a 6-months follow-up (new diagnosis, staging or treatment upgrade) were collected, thereby evaluating the added value of the 344\ub0 panoramic-view (lesions detected by camera A and B) over the standard 172\ub0-view (lesions detected by one camera only). Results: Among 41 patients (aged 43 \ub1 20 years), 73% underwent CE for suspected CD and 27% for established CD. The rate of complete enteroscopy was 90%. No technical failure or retention occurred. Compared to the standard 172\ub0 view, the panoramic 344\ub0-view revealed a greater number of patients with a relevant lesion (56.1% vs. 39.0%; P = 0.023), resulting in higher Lewis score (222,8 vs. 185.7; P = 0.031), and improved clinical management (48.8% vs. 31.7%, P = 0.023). Conclusions: The panoramic 344\ub0-view increases small-bowel CE accuracy, thereby improving the clinical management of CD patients with mild small-bowel active disease. This system should be regarded as a new standard for both small-bowel diagnosis and monitoring in inflammatory bowel diseases

Response of microchannel plates in ionization mode to single particles and electromagnetic showers

Hundreds of concurrent collisions per bunch crossing are expected at future hadron colliders. Precision timing calorimetry has been advocated as a way to mitigate the pileup effects and, thanks to their excellent time resolution, microchannel plates (MCPs) are good candidate detectors for this goal. We report on the response of MCPs, used as secondary emission detectors, to single relativistic particles and to electromagnetic showers. Several prototypes, with different geometries and characteristics, were exposed to particle beams at the INFN-LNF Beam Test Facility and at CERN. Their time resolution and efficiency are measured for single particles and as a function of the multiplicity of particles. Efficiencies between 50% and 90% to single relativistic particles are reached, and up to 100% in presence of a large number of particles. Time resolutions between 20ps and 30ps are obtained.Comment: 20 pages, 9 figures. Paper submitted to NIM

School Feeding Programs in Middle Childhood and Adolescence

Almost every country in the world has a national school feeding program to provide daily snacks or meals to school-attending children and adolescents. The interven- tions reach an estimated 368 million children and ado- lescents globally. The total investment in the intervention is projected to be as much as US$75 billion annually (WFP 2013), largely from government budgets. School feeding may contribute to multiple objectives, including social safety nets, education, nutrition, health, and local agriculture. Its contribution to education objectives is well recognized and documented, while its role as a social safety net was underscored following the food and fuel crises of 2007 and 2008 (Bundy and others 2009). In terms of health and nutrition, school feeding contributes to the continuum of development by build- ing on investments made earlier in the life course, including maternal and infant health interventions and early child development interventions (see chapter 7 in this volume, Alderman and others 2017). School feeding may also help leverage global efforts to enhance the inclusiveness of education for out-of-school children, adolescent girls, and disabled persons, as called for in the Sustainable Development Goals (see chapter 17 in this volume, Graham and others 2017). Although the Disease Control Priorities series focuses on low- and middle-income countries (LMICs), evidence from high-income countries (HICs) is included because of the near universality of school feeding and the insights that inclusion can provide as economies develop. For example, the design of school feeding in countries under- going the nutrition transition 1 may provide some lessons on how to shift from providing access to sufficient calo- ries to promoting healthful diets and dietary behaviors for children and adolescents (WFP 2013). Agricultural development has increasingly gained attention. It is clear that to enable the transition to sus- tainable, scalable government-run programs, the inclu- sion of the agricultural sector is essential (Bundy and others 2009; Drake and others 2016). Accounting for the full benefits of school feeding through cost- effectiveness and benefit-cost analysis is challenging, similar to other complex interventions, but undertaking this accounting is critical for assessing the tradeoffs with competing investments. This chapter reviews the evidence about how school feeding meets these objectives and provides some indi- cation of costs in relation to benefits. The costs of the intervention are well established; estimates that encompass all the benefits of school feeding are more challenging. The benefits must be quantified and translated to the same unit to allow for aggregation. Moreover, how school feeding interventions are designed and implemented varies significantly across countries. Given that delivery of school feeding often involves multiple sectors, common policy frameworks and cross-sectoral coordination are required to achieve maximum benefit (Bundy and others 2009). Several other chapters in the volume highlight school feeding. These include chapter 11 (Lassi, Moin, and Bhutta 2017), chapter 20 (Bundy and others 2017), chapter 22 (Plaut and others 2017), and chapter 25 (Fernandes and Aurino 2017)

Optical properties of silicon-implanted polycrystalline diamond membranes

We investigate the optical properties of polycrystalline diamond membranes containing silicon-vacancy (SiV) color centers in combination with other nano-analytical techniques. We analyze the correlation between the Raman signal, the SiV emission, and the background luminescence in the crystalline grains and in the grain boundaries, identifying conditions for the addressability of single SiV centers. Moreover, we perform a scanning transmission electron microscopy (STEM) analysis, which associates the microscopic structure of the membranes and the evolution of the diamond crystal along the growth direction with the photoluminescence properties, as well as a time-of-flight secondary ion mass spectrometry (ToF-SIMS) to address the distribution of silicon in implanted and un-implanted membranes. The results of the STEM and ToF-SIMS studies are consistent with the outcome of the optical measurements and provide useful insight into the preparation of polycrystalline samples for quantum nano-optics.Comment: 21 pages, 8 figure

High intensity neutrino oscillation facilities in Europe

The EUROnu project has studied three possible options for future, high intensity neutrino oscillation facilities in Europe. The first is a Super Beam, in which the neutrinos come from the decay of pions created by bombarding targets with a 4 MW proton beam from the CERN High Power Superconducting Proton Linac. The far detector for this facility is the 500 kt MEMPHYS water Cherenkov, located in the Fréjus tunnel. The second facility is the Neutrino Factory, in which the neutrinos come from the decay of μ+ and μ− beams in a storage ring. The far detector in this case is a 100 kt magnetized iron neutrino detector at a baseline of 2000 km. The third option is a Beta Beam, in which the neutrinos come from the decay of beta emitting isotopes, in particular He6 and Ne18, also stored in a ring. The far detector is also the MEMPHYS detector in the Fréjus tunnel. EUROnu has undertaken conceptual designs of these facilities and studied the performance of the detectors. Based on this, it has determined the physics reach of each facility, in particular for the measurement of CP violation in the lepton sector, and estimated the cost of construction. These have demonstrated that the best facility to build is the Neutrino Factory. However, if a powerful proton driver is constructed for another purpose or if the MEMPHYS detector is built for astroparticle physics, the Super Beam also becomes very attractive

A survey of high-z galaxies: serra simulations

We introduce SERRA, a suite of zoom-in high-resolution (1.2 ×104 M⊙, ≃ 25 pc at z = 7.7) cosmological simulations including non-equilibrium chemistry and on-the-fly radiative transfer. The outputs are post-processed to derive galaxy ultraviolet (UV) + far-infrared (FIR) continuum and emission line properties. Results are compared with available multiwavelength data to constrain the physical properties [e.g. star formation rates (SFRs), stellar/gas/dust mass, metallicity] of high-redshift 6 ≲ z ≲ 15 galaxies. This flagship paper focuses on the z = 7.7 sub-sample, including 202 galaxies with stellar mass 107 M⊙ ≲ M⊙ ≲ 5 ×1010 M⊙, and specific star formation rate ranging from sSFR ∼100 Gyr-1 in young, low-mass galaxies to ∼10 Gyr-1 for older, massive ones. At this redshift, SERRA galaxies are typically bursty, i.e. they are located abo v e the Schmidt-Kennicutt relation by a factor κs = 3.03+4.9-1.8, consistent with recent findings for [O III ] and [C II ] emitters at high z. They also show relatively large InfraRed eXcess (IRX = LFIR/LUV) values as a result of their compact/clumpy morphology effectively blocking the stellar UV luminosity. Note that this conclusion might be affected by insufficient spatial resolution at the molecular cloud level. We confirm that early galaxies lie on the standard [C II ] -SFR relation; their observed L[OIII]/L [CII] ≃ 1-10 ratios can be reproduced by a part of the SERRA galaxies without the need of a top-heavy initial mass function and/or anomalous C/O abundances. [O I] line intensities are similar to local ones, making ALMA high-z detections challenging but feasible ( ∼6 h for an SFR of 50 M⊙yr-1)

Study of the threshold anomaly effect in the reaction 7 Li+ 208 Pb at energies around the Coulomb barrier

The elastic scattering in the reaction7Li+208Pb was investigated in the bombarding energy range from 25 to39 MeV. The real and imaginary parts of the optical potential were analyzed by using a phenomenological potential. A dispersion relation analysis is presented in order to investigate the threshold anomaly effect. It is concluded that7Li has an intermediate behavior between the tightly bound nuclei suchas16O and the loosely bound nuclei such as6Li where the lack of the threshold anomaly is unambiguously observed.Reaction cross sections are also extracted from the elastic scattering data and its comparison with the ones of other systems has been performed to draw hints on the effect of the breakup channel