La tecnología que aprende a elegir tu talla de calzado

Ballester Fernandez, A.; Gil Mora, S.; Valero, J.; Gonzalez Garcia, JC.; Remon Gomez, A. (2019). La tecnología que aprende a elegir tu talla de calzado. Innovación biomecánica en Europa. (8):1-3. http://hdl.handle.net/10251/167979S13

Proyecto de Innovación Docente “MarWatching”

Hay a disposición una serie de videos públicos que complementan el tutorial de MyOcean del Capítulo 4 (https://www.youtube.com/playlist?list=PLd7A9IeroEZgAnLudkqbXRAA8bxJrPXJe).El presente documento, financiado por el Programa de Investigación en Docencia Universitaria de la Universidad 2021-22 (Xarxa 5543) tiene el objetivo de facilitar el uso de una serie de herramientas que permitan el estudio y análisis del cambio climático en el ámbito universitario de forma transversal. La base de datos de Copernicus, Programa de Observación de la Tierra de la Unión Europea, en su sección marina (Copernicus Marine Service; https://marine.copernicus.eu/) alberga una infinidad de datos que pueden ser difíciles de manejar por docentes y estudiantes. En concreto, se pretende facilitar el empleo de la herramienta MyOcean de Copernicus (https://marine.copernicus.eu/access-data/ocean-visualisation-tools) a través de este manual y de un curso Moodle y Mooc que estarán disponibles en la web de la UA.REDES DE CALIDAD, INNOVACIÓN E INVESTIGACIÓN EN DOCENCIA UNIVERSITARIA. CONVOCATORIA 2021-22 Vicerrectorat de Transformació Digital. Institut de Ciències de l'Educació

BASE PROTECTION, apuesta por la tecnología del IBV para recomendar el modelo y la talla de calzado que mejor se ajusta a cada usuario

[ES] Para que un sistema de recomendación de talla de calzado se considere fiable debe fundamentarse en el ajuste o relación entre la forma interior del calzado y la forma del pie. Para ello es clave el escaneado preciso del pie en 3D y la generación de modelos estadísticos para la predicción del ajuste. Para su transferencia a las empresas, la tecnología debe ser fácilmente integrable en su modelo de negocio y escalable. El Instituto de Biomecánica (IBV) cuenta con la tecnología y las herramientas para escanear el pie del usuario y usar esta información para la selección del modelo y la talla de calzado que mejor se ajusta a cada usuario. También permite asignar la anatomía de la plantilla que mejor se adapta a la forma del pie. El IBV ha colaborado con la empresa BASE PROTECTION licenciando la app 3D Avatar Feet/IBV, que captura la forma del pie con tan solo 3 fotos, y adaptando los algoritmos que permiten asignar la talla del calzado que mejor se ajusta, así como la plantilla más adecuada a cada usuario en función de su anatomía plantarSolves Camallonga, C.; Gonzalez Garcia, JC.; Gil Mora, S.; Ballester Fernandez, A.; Valero Zorraquino, J.; Nacher Fernandez, B.; Alemany Mut, MS. (2020). BASE PROTECTION, apuesta por la tecnología del IBV para recomendar el modelo y la talla de calzado que mejor se ajusta a cada usuario. Revista de Biomecánica (Online). (67):1-5. http://hdl.handle.net/10251/176144S156

Spirometric phenotypes from early childhood to young adulthood : a Chronic Airway Disease Early Stratification study

Acknowledgements Cohort-specific acknowledgements are presented in the supplementary material. We also acknowledge collaboration with the EXPANSE consortium (funded by the EU H2020 programme, grant number 874627). We thank Elise Heuvelin, European Respiratory Society, Lausanne, Switzerland, for her assistance on the current project.Peer reviewedPublisher PD

Global disparities in surgeons’ workloads, academic engagement and rest periods: the on-calL shIft fOr geNEral SurgeonS (LIONESS) study

: The workload of general surgeons is multifaceted, encompassing not only surgical procedures but also a myriad of other responsibilities. From April to May 2023, we conducted a CHERRIES-compliant internet-based survey analyzing clinical practice, academic engagement, and post-on-call rest. The questionnaire featured six sections with 35 questions. Statistical analysis used Chi-square tests, ANOVA, and logistic regression (SPSS® v. 28). The survey received a total of 1.046 responses (65.4%). Over 78.0% of responders came from Europe, 65.1% came from a general surgery unit; 92.8% of European and 87.5% of North American respondents were involved in research, compared to 71.7% in Africa. Europe led in publishing research studies (6.6 ± 8.6 yearly). Teaching involvement was high in North America (100%) and Africa (91.7%). Surgeons reported an average of 6.7 ± 4.9 on-call shifts per month, with European and North American surgeons experiencing 6.5 ± 4.9 and 7.8 ± 4.1 on-calls monthly, respectively. African surgeons had the highest on-call frequency (8.7 ± 6.1). Post-on-call, only 35.1% of respondents received a day off. Europeans were most likely (40%) to have a day off, while African surgeons were least likely (6.7%). On the adjusted multivariable analysis HDI (Human Development Index) (aOR 1.993) hospital capacity > 400 beds (aOR 2.423), working in a specialty surgery unit (aOR 2.087), and making the on-call in-house (aOR 5.446), significantly predicted the likelihood of having a day off after an on-call shift. Our study revealed critical insights into the disparities in workload, access to research, and professional opportunities for surgeons across different continents, underscored by the HDI

Cabbage and fermented vegetables : From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.Peer reviewe

Nrf2-interacting nutrients and COVID-19 : time for research to develop adaptation strategies

There are large between- and within-country variations in COVID-19 death rates. Some very low death rate settings such as Eastern Asia, Central Europe, the Balkans and Africa have a common feature of eating large quantities of fermented foods whose intake is associated with the activation of the Nrf2 (Nuclear factor (erythroid-derived 2)-like 2) anti-oxidant transcription factor. There are many Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) that all act similarly to reduce insulin resistance, endothelial damage, lung injury and cytokine storm. They also act on the same mechanisms (mTOR: Mammalian target of rapamycin, PPAR gamma:Peroxisome proliferator-activated receptor, NF kappa B: Nuclear factor kappa B, ERK: Extracellular signal-regulated kinases and eIF2 alpha:Elongation initiation factor 2 alpha). They may as a result be important in mitigating the severity of COVID-19, acting through the endoplasmic reticulum stress or ACE-Angiotensin-II-AT(1)R axis (AT(1)R) pathway. Many Nrf2-interacting nutrients are also interacting with TRPA1 and/or TRPV1. Interestingly, geographical areas with very low COVID-19 mortality are those with the lowest prevalence of obesity (Sub-Saharan Africa and Asia). It is tempting to propose that Nrf2-interacting foods and nutrients can re-balance insulin resistance and have a significant effect on COVID-19 severity. It is therefore possible that the intake of these foods may restore an optimal natural balance for the Nrf2 pathway and may be of interest in the mitigation of COVID-19 severity

Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis

Objectives To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study. Design Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined. Setting Children aged 0–18 years from 26 European birth cohorts. Participants 136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood. Main outcome measure Questionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity) at age 6–18 years. Results Questionnaire-based and accelerometry-based PA and sedentary behaviour at age 3–5 years was not associated with asthma at age 6–18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results. Conclusions Reduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood. Data availability statement Due to data protection reasons, the datasets generated during the current study cannot be made publicly available. The cohort-specific datasets are available to interested researchers on reasonable request, provided the release is consistent with the obtained consent of the study participants of the cohort. This will not be possible for all cohorts involved. Ethical approval might be necessary to be obtained for the release and a data transfer agreement must be accepted

Compuesto inhibidor dual de las enzimas PDE7 y/o PDE4, composiciones farmacéuticas y sus aplicaciones

La invención describe una serie de inhibidores duales de las enzimas PDE7 y PDE4 de fórmula (I) y su utilidad para la elaboraciónde composiciones farmacéuticas para el tratamiento de procesos 5inflamatorios y/o autoinmunes.Cuando una patente se hace internacional, se puede encontrar en el idioma de cada país en que se ha solicitado. En Espacenet se tiene acceso a los documentos en cada idioma.Consejo Superior de Invesrtigaciones Científicas; Instituto de Salud Carlos IIISolicitud de patent

Innovation for Children

[EN] Design4Children is the most ambitious European project carried out in relation to the design of products for children. It is coordinated by the Spanish Association of products for children (ASEPRI) and involves 12 entities the first year of the project, just ended, the IBV has played a fundamental role generating knowledge, inexistent to date, to satisfy the comfort and safety needs of children from 0 to 12 years. This knowledge includes the perception that parents have about children¿s product in the market and specific design criteria for children¿s products to ensure the health of children and the comfort and usability of parents. In addition, it has been defined the specifications of a set of innovative tools, that will be developed over the next two years, and will support designers allowing to introduce scientific knowledge regarding products comfort and usability into the design process to ensure the comfort and welfare of children throughout the process of developing new products, advising parents to buy and retailers to select the best products for sale. (R&D centers, associations and companies). With a budget of 1.5M Euros, it covers 3 years. During[ES] Design4Children es el proyecto europeo más ambicioso que se ha llevado a cabo en relación con el diseño de productos para la infancia. Está coordinado por la Asociación Española de Productos para la Infancia (ASEPRI) y participan 12 entidades (centros de I+D, asociaciones y empresas). Con un presupuesto de 1.5 millones de Euros, tiene una duración de 3 años. Durante el primer año del proyecto, que acaba de finalizar, el Instituto de Biomecánica (IBV) ha desarrollado un papel fundamental en la generación de conocimiento, inexistente hasta ahora, relativo a las necesidades en materia de confort y seguridad de la población infantil de 0 a 12 años, así como sobre la percepción que los padres tienen del producto infantil actualmente en el mercado, se han generado criterios de diseño específicos para productos infantiles que aseguren la salud de niños y el confort y usabilidad para los padres. Además, se han definido las especificaciones de un set de herramientas informáticas innovadoras que serán desarrolladas a lo largo de los dos próximos años, y que darán apoyo a los diseñadores. Estas herramientas permitirán a éstos introducir conocimiento científico para asegurar el confort y el bienestar de los niños a lo largo del proceso de desarrollo de nuevos productos, a los padres les aconsejará en la compra y a los minoristas les ayudará en la selección de los productos óptimos para la venta.También queremos dar las gracias a la Comisión Europea por el apoyo financiero brindado en la realización del proyecto dentro de la convocatoria del 7º programa marco "Research for SME associations"Olaso Melis, J.; Ballester Fernández, A.; Hernández Alonso, A.; Gil Garcia, M.; Gonzalez Garcia, JC.; Gil Mora, S.; Iranzo Martínez, L.... (2011). Innovación para los más pequeños. Revista de biomecánica. (57):35-40. http://hdl.handle.net/10251/38459S35405