Preliminary evaluation of a blast sprayer controlled by pulse width modulated nozzles

[EN] Precision spraying relies on the response of the spraying equipment to the features of the targeted canopy. PWM technology manages the flow rate using a set of electronically actuated solenoid valves to regulate flow rate at the nozzle level. Previous studies have found that PWM systems may deliver incorrect flow rates. The objective of the present study was to characterize the performance of a commercial blast sprayer modified with pulse-width-modulated nozzles under laboratory conditions, as a preliminary step before its further field validation. Four different duty cycles (25 percent, 50 percent, 75 percent and 100 percent) and four different pressures (400 kPa, 500 kPa, 600 kPa and 700 kPa) were combined to experimentally measure the flow rate of each nozzle. Results showed that the PWM nozzles mounted in the commercial blast sprayer, under static conditions, were capable of modulating flow rate according to the duty cycle. However, the reduction of flow rates for the tested duty cycles according to pressure was lower than the percentage expected. A good linear relation was found between the pressure registered by the control system feedback sensor and the pressure measured by a reference conventional manometer located after the pump. High-speed video recordings confirmed the accurate opening and closing of the nozzles according to the duty cycle; however, substantial pressure variations were found at nozzle level. Further research to establish the general suitability of PWM systems for regulating nozzle flow rates in blast sprayers without modifying the system pressure still remains to be addressed.This research was funded by the Government of Spain through the project "Smart spraying for a sustainable vineyard and olive trees" PIVOS (PID2019-104289RB).Ortí García, E.; Cuenca, A.; Pérez Teruel, M.; Torregrosa, A.; Ortiz Sánchez, MC.; Rovira Más, F. (2022). Preliminary evaluation of a blast sprayer controlled by pulse width modulated nozzles. Sensors. 22(13):1-12. https://doi.org/10.3390/s22134924112221

The impact of associated tenotomies on the outcome of incomplete phalangeal osteotomies for lesser toe deformities

Partial or incomplete osteotomy (IO) of the phalanx is recently described in the literature. However, the clinical outcome and the rate of complications when applied to lesser toe deformities (LTD) have been never addressed. This study aims to find out if the association of tenotomies to incomplete or partial phalanx osteotomies has a significant impact on the clinical outcomes, the occurrence of complications, and the recovery time after surgery. Methods: A retrospective review of two cohorts of cases operated in our institution for hallux abductus valgus (HAV) and associated LTD from 2008 to 2014 was carried out. The surgical correction of both HAV and the associated LTD was always performed by minimally invasive techniques. The study included a total of 223 patients (723 IO in 556 toes). In 129 cases, the IO for LTD correction was performed without tenotomies, and in 94, the procedure was combined with flexor and/or extensor tenotomies. Patients were assessed with the American Orthopaedic Foot and Ankle Society (AOFAS) questionnaire before surgery and at 6- and 12-month follow-up. Results: The mean preoperative AOFAS score before surgery was similar in both cohorts. At 12-month follow-up, the cohort without tenotomies showed better recovery (95.7 ± 2.8 versus 92.5 ± 6.8; p < 0.01). AOFAS scores decreased as the number of associated LTD increased (r = − 0.814; p < 0.001). Cases operated on by PO + tenotomy showed a high rate of complications such as delayed union of the osteotomy (p < 0.01), hypertrophic callus (p < 0.01), phalangeal fracture at the osteotomy site (p < 0.01), and lack of correction (p < 0.05). The overall occurrence of adverse events was 38.6% in cases operated by PO + tenotomy and 13.9% in cases receiving PO alone (p < 0.0001). Cases operated on without tenotomy showed a shorter time to complete recovery for daily life activities (37.4 ± 2.3 versus 43.0 ± 1.7 days; p < 0.01). Conclusion: The performance of associated tenotomies to incomplete phalanx osteotomies provides worse clinical outcomes, higher complication rates, and longer recovery time as compared to similar forefoot surgeries without tenotomies.Podologí

Theoretical and experimental study of mechanical losses in automotive turbochargers

The aim of the present work is to show an approximation, through an experimental an theoretical study, to quantify the mechanical losses in a turbocharging system. These are linked to the dynamics in the turbo shaft bearings, both axial and radial. Theoretical and experimental methodologies are presented in order to develop a mechanical losses model. The experimental work consists on a measurement campaign in quasi-adiabatic operating conditions, while in the theoretical part, a mathematical model is developed taking into account the radial and axial bearings. The model uses some assumptions in order to solve the Navier-Stokes equations, leading to a simplified model which includes viscosity and the Reynolds number of the oil film formed on the bearings. The proposed model has shown a good agreement with the experimental dataThe authors of this paper wish to thank M.A. Ortiz and V. Ucedo for their invaluable work during the experimental setup and campaign, F.J. Arnau, Ph.D, for its excellent job maintaining and expanding Open WAMs code base and M.A. Reyes-Belmonte for all his hard and rigorous work extrapolating turbine maps and preparing and launching the simulations. This work has been partially supported by the Spanish Ministerio de Ciencia e Innovacion through grant number DPI2010-20891-C02-02.Serrano Cruz, JR.; Olmeda González, PC.; Tiseira Izaguirre, AO.; García-Cuevas González, LM.; Lefebvre, A. (2013). Theoretical and experimental study of mechanical losses in automotive turbochargers. Energy. 55:888-898. https://doi.org/10.1016/j.energy.2013.04.042S8888985

Fabry Nephropathy: An Evidence-Based Narrative Review.

Fabry disease (FD) is a rare, X-linked disorder caused by mutations in the GLA gene encoding the enzyme α-galactosidase A. Complete or partial deficiency in this enzyme leads to intracellular accumulation of globotriaosylceramide (Gb3) and other glycosphingolipids in many cell types throughout the body, including the kidney. Progressive accumulation of Gb3 in podocytes, endothelial cells, epithelial cells, and tubular cells contribute to the renal symptoms of FD, which manifest as proteinuria and reduced glomerular filtration rate leading to renal insufficiency. A correct diagnosis of FD, although challenging, has considerable implications regarding treatment, management, and counseling. The diagnosis may be confirmed by demonstrating the enzyme deficiency in males and by identifying the specific GLA gene mutation in male and female patients. Treatment with enzyme replacement therapy, as part of the therapeutic strategy to prevent complications of the disease, may be beneficial in stabilizing renal function or slowing its decline, particularly in the early stages of the disease. Emergent treatments for FD include the recently approved chaperone molecule migalastat for patients with amenable mutations. The objective of this report is to provide an updated overview on Fabry nephropathy, with a focus on the most relevant aspects of its epidemiology, diagnosis, pathophysiology, and treatment options.S

Clinical practice guideline for surgical antimicrobial prophylaxis

La infección del sitio quirúrgico (ISQ) es una de las principales causas de infecciones asociadas a la atención en salud (IAAS), con un impacto significativo en la mortalidad y morbilidad del paciente quirúrgico, así como en los costos asociados a la atención en salud. El adecuado uso de la profilaxis quirúrgica antimicrobiana es un aspecto fundamental en la reducción del riesgo de ISQ, dado que su utilización inapropiada o indiscriminada puede representar un riesgo para los pacientes y contribuir al desarrollo de resistencia a los antimicrobianos, por lo que resulta de importancia generar directrices que permitan orientar el uso adecuado de antimicrobianos en la profilaxis del paciente quirúrgico, con el objetivo de obtener mejores desenlaces clínicos y propender por un uso racional de antibióticos. La presente guía contiene recomendaciones para profilaxis antibiótica de pacientes sometidos a procedimiento quirúrgico, basadas en la evidencia, realizadas mediante el proceso de adaptación de guías de práctica clínica para el contexto colombiano.Q4Pacientes sometidos a Profilaxis quirúrgica antimicrobianaSurgical site infection (SSI) is one of the main causes of healthcare associated infections (HAI), with a significant impact on the mortality and morbidity of the surgi-cal patient, as well as on the costs associated with health care. The adequate use of surgical antimicrobial prophylaxis being a fundamental aspect in reducing the risk of SSI, taking into account that the inappropriate or indiscriminate use of antibiotics in surgical prophylaxis may represent a risk for patients and contribute to the development of antimicrobial resistance, so it is important to generate guidelines that guide the appropriate antimicrobial prophylaxis in the surgical patient, with the aim of obtaining better clinical outcomes and promoting a rational use of antibiotics. This guide contains recommendations for antibiotic prophylaxis in patients undergoing a surgical procedure, based on evidence, carried out through the process of adapting clinical practice guidelines for the Colombian context.https://orcid.org/0000-0002-5392-7083https://orcid.org/0000-0003-2568-4667Revista Nacional - IndexadaCN

III Jornadas de Jóvenes Investigadores en Arqueología: Libro de Actas

Libro de Actas de las III Jornadas de Jóvenes Investigadores en Arqueologí

Whole-genome genotyping of grape using a panel of microsatellite

The use of microsatellite markers in large-scale genetic studies is limited by its low throughput and high cost and labor requirements. Here, we provide a panel of 45 multiplex PCRs for fast and cost-efficient genome-wide fluorescence-based microsatellite analysis in grapevine. The developed multiplex PCRs panel (with up to 15-plex) enables the scoring of 270 loci covering all the grapevine genome (9 to 20 loci/chromosome) using only 45 PCRs and sequencer runs. The 45 multiplex PCRs were validated using a diverse grapevine collection of 207 accessions, selected to represent most of the cultivated Vitis vinifera genetic diversity. Particular attention was paid to quality control throughout the whole process (assay replication, null allele detection, ease of scoring). Genetic diversity summary statistics and features of electrophoretic profiles for each studied marker are provided, as are the genotypes of 25 common cultivars that could be used as references in other studies

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

On the application of artificial neural network for the development of a nonlinear aeroelastic model

[EN] Aeroelastic Computational Fluid Dynamics simulations have traditionally been associated to a high computational cost, making them prohibitive in a initial phase of the design. Analytic models, which may not be accurate for nonlinear aerodynamics, have traditionally been utilized in order to size those structures. Recently, some authors have proposed the use of artificial neural networks to reduce the error in the prediction of aerodynamic coefficients of bluff bodies, which have separated flow over a substantial part of its wetted surface. This article proposes a method based on neural networks for calculating the dynamic aerodynamic coefficients of a flat plate. The procedure, which is applied for different network typologies (feed-forward and long-short term memory neural networks), is, then, coupled with a structural solver in order to create an aeroelastic reduced order model. The results are compared with CFD aeroelastic simulations, showing a high reduction of computational cost (99%) without penalties in the accuracy. The instabilities are captured and the mean deformation, amplitude and frequency of the motion are predicted. In addition, the different neural network models are compared evidencing that for the aeroelastic calculation feed-forward networks are most efficient in terms of accuracy and computational cost.This project has beenpartially funded by Spanish Ministry of Science, Innovation and Universities through the University Faculty Training (FPU) program with reference FPU19/02201.Torregrosa, AJ.; García-Cuevas González, LM.; Quintero-Igeño, P.; Cremades-Botella, A. (2021). On the application of artificial neural network for the development of a nonlinear aeroelastic model. Aerospace Science and Technology. 115:1-15. https://doi.org/10.1016/j.ast.2021.106845S11511