13 research outputs found
ALMA observations of polarized emission toward the CW Tau and DG Tau protoplanetary disks: constraints on dust grain growth and settling
We present polarimetric data of CW Tau and DG Tau, two well-known Class II
disk/jet systems, obtained with the Atacama Large Millimeter/submillimeter
Array at 870 m and 0."2 average resolution. In CW Tau, the total and
polarized emission are both smooth and symmetric, with polarization angles
almost parallel to the minor axis of the projected disk. In contrast, DG Tau
displays a structured polarized emission, with an elongated brighter region in
the disk's near side and a belt-like feature beyond about 0."3 from the source.
At the same time the total intensity is spatially smooth, with no features. The
polarization pattern, almost parallel to the minor axis in the inner region,
becomes azimuthal in the outer belt, possibly because of a drop in optical
depth. The polarization fraction has average values of 1.2% in CW Tau and 0.4%
in DG Tau. Our results are consistent with polarization from self-scattering of
the dust thermal emission. Under this hypothesis, the maximum size of the
grains contributing to polarization is in the range 100 - 150 m for CW Tau
and 50 - 70 m for DG Tau. The polarization maps combined with dust opacity
estimates indicate that these grains are distributed in a geometrically thin
layer in CW Tau, representing a settling in the disk midplane. Meanwhile, such
settling is not yet apparent for DG Tau. These results advocate polarization
studies as a fundamental complement to total emission observations, in
investigations of the structure and the evolution of protoplanetary disks.Comment: 8 pages, 5 figures. Accepted for publication in ApJ Letter
PRISM (Polarized Radiation Imaging and Spectroscopy Mission): A White Paper on the Ultimate Polarimetric Spectro-Imaging of the Microwave and Far-Infrared Sky
PRISM (Polarized Radiation Imaging and Spectroscopy Mission) was proposed to
ESA in response to the Call for White Papers for the definition of the L2 and
L3 Missions in the ESA Science Programme. PRISM would have two instruments: (1)
an imager with a 3.5m mirror (cooled to 4K for high performance in the
far-infrared---that is, in the Wien part of the CMB blackbody spectrum), and
(2) an Fourier Transform Spectrometer (FTS) somewhat like the COBE FIRAS
instrument but over three orders of magnitude more sensitive. Highlights of the
new science (beyond the obvious target of B-modes from gravity waves generated
during inflation) made possible by these two instruments working in tandem
include: (1) the ultimate galaxy cluster survey gathering 10e6 clusters
extending to large redshift and measuring their peculiar velocities and
temperatures (through the kSZ effect and relativistic corrections to the
classic y-distortion spectrum, respectively) (2) a detailed investigation into
the nature of the cosmic infrared background (CIB) consisting of at present
unresolved dusty high-z galaxies, where most of the star formation in the
universe took place, (3) searching for distortions from the perfect CMB
blackbody spectrum, which will probe a large number of otherwise inaccessible
effects (e.g., energy release through decaying dark matter, the primordial
power spectrum on very small scales where measurements today are impossible due
to erasure from Silk damping and contamination from non-linear cascading of
power from larger length scales). These are but a few of the highlights of the
new science that will be made possible with PRISM.Comment: 20 pages Late
Anatomo-radiological study of the superficial musculo-aponeurotic system of the face.
The aim of the study was to analyse the appearance of the superficial muscolo-aponeurotic system (SMAS) in radiological images (Magnetic Resonance -MR- and Computed tomography -CT- scans, 10M, 10F randomly selected) in the three regions of the face (the parotid and cheek regions and the nasolabial fold). In axial CT images, the SMAS appears as a relatively hyperdense tortuous line between the hypodense superficial fibroadipose tissue (SAT) and the hypodense deep adipose tissue (DAT). In parotid region SAT is well represented (mean thickness 4.32 +/- 2.9 mm), whereas DAT is very thin (0.33 +/- 0.48 mm); SMAS appears as a thin hyperdense line, close to the parotid gland (0.76 +/- 0.43 mm). In cheek region, SAT is well represented (5.57 +/- 1.17 mm), whereas DAT is thinner (2.94 +/- 0.62 mm), and SMAS is well recognisable (1.69 +/- 0.52 mm). At the level of the nasolabial fold, the SAT is poorly represented (0.37 +/- 0.06 mm); the SMAS continues in the mimic muscles (2.41 +/- 0.05 mm), and DAT shows a mean thickness of 2.15 +/- 0.63 mm. In the MR examination, the SMAS appears as a thin continuous line hypointense in the T1-and T2-weighted sequence, from parotid region to nasolabial fold, comprising mimic muscles in the anterior region of the cheek and at the level of the nasolabial fold. No significative differences in thickness between CT and MR were found. Our anatomo-radiological study confirms that the subcutaneous architecture of the face consists of multiple layers of tissues that connect facial muscles with the dermis. This pattern of arrangement shows a progressive centrifugal thinning towards the adjacent regions
Concomitant recovery from left spatial neglect and inflammatory dysfunction of white-matter pathways in a case of acute disseminated encephalo-myelitis (ADEM)
Timing of intrathecal baclofen therapy in persons with acquired brain injury: Influence on outcome
PRISM (Polarized Radiation Imaging and Spectroscopy Mission): an extended white paper
Contains fulltext :
126057.pdf (preprint version ) (Open Access
Timing of Muscle Response to a Sudden Leg Perturbation: Comparison between Adolescents and Adults with Down Syndrome
Brivaracetam as add-on treatment in patients with post-stroke epilepsy: real-world data from the BRIVAracetam add-on First Italian netwoRk Study (BRIVAFIRST)
Objective: Post-stroke epilepsy (PSE) is one of the most common causes of acquired epilepsy and accounts for about 10-15% of all newly diagnosed epilepsy cases. However, evidence about the clinical profile of antiseizure medications in the PSE setting is currently limited. Brivaracetam (BRV) is a rationally developed compound characterized by high-affinity binding to synaptic vesicle protein 2A. The aim of this study was to assess the 12-month effectiveness and tolerability of adjunctive BRV in patients with PSE treated in a real-world setting. Methods: This was a subgroup analysis of patients with PSE included in the BRIVAracetam add-on First Italian netwoRk Study (BRIVAFIRST). The BRIVAFIRST was a 12-month retrospective, multicentre study including adult patients prescribed adjunctive BRV. Effectiveness outcomes included the rates of seizure response (â„50% reduction in baseline seizure frequency), seizure-freedom, and treatment discontinuation. Safety and tolerability outcomes included the rate of treatment discontinuation due to adverse events (AEs) and the incidence of AEs. Results: Patients with PSE included in the BRIVAFIRST were 75 and had a median age of 57 (interquartile range, 42-66) years. The median daily doses of BRV at 3, 6, and 12 months from starting treatment were 100 (100-150) mg, 125 (100-200) mg and 100 (100-200) mg, respectively. At 12 months, 32 (42.7%) patients had a reduction in their baseline seizure frequency by at least 50%, and the seizure freedom rates was 26/75 (34.7%). During the 1-year study period, 10 (13.3%) patients discontinued BRV. The reasons of treatment withdrawal were insufficient efficacy in 6 (8.0%) patients and poor tolerability in 4 (5.3%) patients. Adverse events were reported by 13 (20.3%) patients and were rated as mild in 84.6% and moderate in 15.4% of cases. Significance: Adjunctive BRV was efficacious and generally well-tolerated when used in patients with PSE in clinical practice. Adjunctive BRV can be a suitable therapeutic option for patients with PSE