Eficacia de la hipnosis en psicologia del deporte. Importancia de la comunicación y estudio de casos

En la historia del desarrollo de los procedimientos médicos y psicológicos, la hipnosis ha protagonizado un papel destacado, siendo una intervención clínica valiosa en el tratamiento de una extensa variedad de problemas. A pesar de ello no se ha librado de controversias y mitos acerca de su naturaleza. En el presente trabajo se revisa el desarrollo histórico de la hipnosis y los modelos explicativos más relevantes, desde aquellos que la consideran un estado alterado de conciencia hasta los que deenden que los fenómenos hipnóticos pueden ser explicados por las mismas variables que la conducta y la experiencia no hipnótica. También se revisan algunas de las definiciones que han surgido desde los distintos paradigmas, así como la evidencia empírica de su eficacia, comprobándose que cuando es utilizada como coadyuvante de los tratamientos médicos y psicológicos incrementa la ecacia de los mismos, siendo de especial relevancia la relación de comunicación que se establece entre clínico y paciente. Se finaliza con una revisión de su aplicación en el ámbito del deporte y la presentación de un estudio de casos (3 atletas y 1 futbolista) en los que se utiliza hipnosis coadyuvante con otras técnicas. En todos los casos se logran resultados óptimos.

Meristematic and meristematic-like fungi in Dothideomycetes

SUPPLEMENTARY MMATERIAL : FIG. S1. Maximum Likelihood (ML) phylogenetic tree of the ITS sequence alignment of the new genus Endophytium and related meristematic and meristematic-like fungi in Dothideomycetes. New taxa are in bold face. Thickened branches indicate full statistical support in all analyses. Confidence values for ML-BS ≥ 70 % (UFboot2/RAxML) are included near the nodes and the “-” indicates statistical support below the threshold values. The scale bar represents the expected number of changes per site. The tree was rooted to Xylaria (Xylariales, Sordariomycetes) and Sordaria (Sordariales, Sordariomycetes). Families and orders are shown in coloured blocks and indicated to the right of the tree. FIG. S2. Maximum Likelihood (ML) phylogenetic tree of the LSU sequence alignment of the new genus Endophytium and related meristematic and meristematic-like fungi in Dothideomycetes. New taxa are in bold face. Thickened branches indicate full statistical support in all analyses. Confidence values for ML-BS ≥ 70 % (UFboot2/RAxML) are included near the nodes and the “-” indicates statistical support below the threshold values. The scale bar represents the expected number of changes per site. The tree was rooted to Xylaria (Xylariales, Sordariomycetes) and Sordaria (Sordariales, Sordariomycetes). Families and orders are shown in coloured blocks and indicated to the right of the tree. FIG. S3. Maximum Likelihood (ML) phylogenetic tree of the SSU sequence alignment of the new genus Endophytium and related meristematic and meristematic-like fungi in Dothideomycetes. New taxa are in bold face. Thickened branches indicate full statistical support in all analyses. Confidence values for ML-BS ≥ 70 % (UFboot2/RAxML) are included near the nodes and the “-” indicates statistical support below the threshold values. The scale bar represents the expected number of changes per site. The tree was rooted to Xylaria (Xylariales, Sordariomycetes) and Sordaria (Sordariales, Sordariomycetes). Families and orders are shown in coloured blocks and indicated to the right of the tree. FIG. S4. Maximum Likelihood (ML) phylogenetic tree of the RPB2 sequence alignment of the new genus Endophytium and related meristematic and meristematic-like fungi in Dothideomycetes. New taxa are in bold face. Thickened branches indicate full statistical support in all analyses. Confidence values for ML-BS ≥ 70 % (UFboot2/RAxML) are included near the nodes and the “-” indicates statistical support below the threshold values. The scale bar represents the expected number of changes per site. The tree was rooted to Xylaria (Xylariales, Sordariomycetes) and Sordaria (Sordariales, Sordariomycetes). Families and orders are shown in coloured blocks and indicated to the right of the tree. TABLE S1. Summary of phylogenetic information for the different analyses in this study. TABLE S2. Species, strains/vouchers and GenBank accession numbers of sequences used in phylogenetic analyses. Newly generated sequences are in bold.Meristematic fungi are mainly defined as having aggregates of thick-walled, melanised cells enlarging and reproducing by isodiametric division. Dothideomycetes black meristematic and meristematic-like fungi have been allied to Myriangiales, which currently has two accepted families, Myriangiaceae and Elsinoaceae, with fungi mainly regarded as pathogens, parasites, saprobes and epiphytes of different plant species. This study aimed to verify the phylogenetic position using four nuclear markers (SSU, LSU, ITS and RPB2) of the incertae sedis genera associated with Myriangiales, namely Endosporium, Gobabebomyces, Lembosiniella and Phaeosclera, and the new genus, Endophytium gen. nov. (including E. albocacti sp. nov. and E. cacti sp. nov.), established for endophytic fungi occurring in cacti in Brazil. Based on morphology, lifestyle and phylogenetic inferences, these black meristematic and meristematic-like fungi cannot be accommodated in Myriangiales. Combining these results, three new orders and two new families are introduced: Endophytiales ord. nov. (including Endophytiaceae fam. nov. for Endophytium gen. nov.), Endosporiales ord. nov. (including Endosporiaceae for Endosporium) and Phaeosclerales ord. nov. (including Phaeoscleraceae fam. nov. for Phaeosclera). Gobabebomyces and Lembosiniella remained incertae sedis due to their disposition in the phylogenetic tree, that moved among clades accordingly with the gene analysed. Our results show that the inclusion of endophytic fungi obtained from plants in dry forests can contribute to the discovery of new taxa, clarify the phylogenetic position of allied taxa and confer information to the estimation of national and global fungal diversity.the Conselho Nacional de Desenvolvimento Científico e Tecnológico, the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, the Financiadora de Estudos e Projetos, the Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco, the Fundação de Amparo à Pesquisa do Estado de Goiás (FAPEG) of Brazil, CAPES, CNPq and the European Union’s Horizon 2020 research and innovation program (RISE) under the Marie Skłodowska-Curie grant agreement No. 101008129.https://fuse-journal.orghj2024BiochemistryForestry and Agricultural Biotechnology Institute (FABI)GeneticsMicrobiology and Plant PathologySDG-15:Life on lan

Moving forward through the in silico modeling of tuberculosis: a further step with UISS-TB

Background In 2018, about 10 million people were found infected by tuberculosis, with approximately 1.2 million deaths worldwide. Despite these numbers have been relatively stable in recent years, tuberculosis is still considered one of the top 10 deadliest diseases worldwide. Over the years, Mycobacterium tuberculosis has developed a form of resistance to first-line tuberculosis treatments, specifically to isoniazid, leading to multi-drug-resistant tuberculosis. In this context, the EU and Indian DBT funded project STriTuVaD—In Silico Trial for Tuberculosis Vaccine Development—is supporting the identification of new interventional strategies against tuberculosis thanks to the use of Universal Immune System Simulator (UISS), a computational framework capable of predicting the immunity induced by specific drugs such as therapeutic vaccines and antibiotics. Results Here, we present how UISS accurately simulates tuberculosis dynamics and its interaction within the immune system, and how it predicts the efficacy of the combined action of isoniazid and RUTI vaccine in a specific digital population cohort. Specifically, we simulated two groups of 100 digital patients. The first group was treated with isoniazid only, while the second one was treated with the combination of RUTI vaccine and isoniazid, according to the dosage strategy described in the clinical trial design. UISS-TB shows to be in good agreement with clinical trial results suggesting that RUTI vaccine may favor a partial recover of infected lung tissue. Conclusions In silico trials innovations represent a powerful pipeline for the prediction of the effects of specific therapeutic strategies and related clinical outcomes. Here, we present a further step in UISS framework implementation. Specifically, we found that the simulated mechanism of action of RUTI and INH are in good alignment with the results coming from past clinical phase IIa trials

Measurement of the p-pbar -> Wgamma + X cross section at sqrt(s) = 1.96 TeV and WWgamma anomalous coupling limits

The WWgamma triple gauge boson coupling parameters are studied using p-pbar -> l nu gamma + X (l = e,mu) events at sqrt(s) = 1.96 TeV. The data were collected with the DO detector from an integrated luminosity of 162 pb^{-1} delivered by the Fermilab Tevatron Collider. The cross section times branching fraction for p-pbar -> W(gamma) + X -> l nu gamma + X with E_T^{gamma} > 8 GeV and Delta R_{l gamma} > 0.7 is 14.8 +/- 1.6 (stat) +/- 1.0 (syst) +/- 1.0 (lum) pb. The one-dimensional 95% confidence level limits on anomalous couplings are -0.88 < Delta kappa_{gamma} < 0.96 and -0.20 < lambda_{gamma} < 0.20.Comment: Submitted to Phys. Rev. D Rapid Communication

Measurement of the ttbar Production Cross Section in ppbar Collisions at sqrt{s} = 1.96 TeV using Kinematic Characteristics of Lepton + Jets Events

We present a measurement of the top quark pair ttbar production cross section in ppbar collisions at a center-of-mass energy of 1.96 TeV using 230 pb**{-1} of data collected by the DO detector at the Fermilab Tevatron Collider. We select events with one charged lepton (electron or muon), large missing transverse energy, and at least four jets, and extract the ttbar content of the sample based on the kinematic characteristics of the events. For a top quark mass of 175 GeV, we measure sigma(ttbar) = 6.7 {+1.4-1.3} (stat) {+1.6- 1.1} (syst) +/-0.4 (lumi) pb, in good agreement with the standard model prediction.Comment: submitted to Phys.Rev.Let

Measurement of the ttbar Production Cross Section in ppbar Collisions at sqrt(s)=1.96 TeV using Lepton + Jets Events with Lifetime b-tagging

We present a measurement of the top quark pair ($t\bar{t}$) production cross section ($\sigma_{t\bar{t}}$) in $p\bar{p}$ collisions at $\sqrt{s}=1.96$ TeV using 230 pb$^{-1}$ of data collected by the D0 experiment at the Fermilab Tevatron Collider. We select events with one charged lepton (electron or muon), missing transverse energy, and jets in the final state. We employ lifetime-based b-jet identification techniques to further enhance the $t\bar{t}$ purity of the selected sample. For a top quark mass of 175 GeV, we measure $\sigma_{t\bar{t}}=8.6^{+1.6}_{-1.5}(stat.+syst.)\pm 0.6(lumi.)$ pb, in agreement with the standard model expectation.Comment: 7 pages, 2 figures, 3 tables Submitted to Phys.Rev.Let

Evidence of Color Coherence Effects in W+jets Events from ppbar Collisions at sqrt(s) = 1.8 TeV

We report the results of a study of color coherence effects in ppbar collisions based on data collected by the D0 detector during the 1994-1995 run of the Fermilab Tevatron Collider, at a center of mass energy sqrt(s) = 1.8 TeV. Initial-to-final state color interference effects are studied by examining particle distribution patterns in events with a W boson and at least one jet. The data are compared to Monte Carlo simulations with different color coherence implementations and to an analytic modified-leading-logarithm perturbative calculation based on the local parton-hadron duality hypothesis.Comment: 13 pages, 6 figures. Submitted to Physics Letters

Measurement of the Isolated Photon Cross Section in p-pbar Collisions at sqrt{s}=1.96 TeV

The cross section for the inclusive production of isolated photons has been measured in p anti-p collisions at sqrt{s}=1.96 TeV with the D0 detector at the Fermilab Tevatron Collider. The photons span transverse momenta 23 to 300 GeV and have pseudorapidity |eta|<0.9. The cross section is compared with the results from two next-to-leading order perturbative QCD calculations. The theoretical predictions agree with the measurement within uncertainties.Comment: 7 pages, 5 figures, submitted to Phys.Lett.

Search for W' bosons decaying to an electron and a neutrino with the D0 detector

This Letter describes the search for a new heavy charged gauge boson W' decaying into an electron and a neutrino. The data were collected with the D0 detector at the Fermilab Tevatron proton-antiproton Collider at a center-of-mass energy of 1.96 TeV, and correspond to an integrated luminosity of about 1 inverse femtobarn. Lacking any significant excess in the data in comparison with known processes, an upper limit is set on the production cross section times branching fraction, and a W' boson with mass below 1.00 TeV can be excluded at the 95% C.L., assuming standard-model-like couplings to fermions. This result significantly improves upon previous limits, and is the most stringent to date.Comment: submitted to Phys. Rev. Let

Improved W boson mass measurement with the D0 detector

We have measured the W boson mass using the D0 detector and a data sample of 82 pb^-1 from the Tevatron collider. This measurement used W -> e nu decays, where the electron is close to a boundary of a central electromagnetic calorimeter module. Such 'edge' electrons have not been used in any previous D0 analysis, and represent a 14% increase in the W boson sample size. For these electrons, new response and resolution parameters are determined, and revised backgrounds and underlying event energy flow measurements are made. When the current measurement is combined with previous D0 W boson mass measurements, we obtain M_W = 80.483 +/- 0.084 GeV. The 8% improvement from the previous D0 measurement is primarily due to the improved determination of the response parameters for non-edge electrons using the sample of Z bosons with non-edge and edge electrons.Comment: submitted to Phys. Rev. D; 20 pages, 18 figures, 9 table