220 research outputs found

    Magnetic spring in oscillating mirror linear scanner for satellite camera

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    One of the main difficulties encountered in the development of a multispectral scanner is the realization of an oscillating mechanical device. A magnetic device which is characterized by the absence of friction is presented. The main developments concern the analysis of magnetic forces. A preliminary project of a device which could be used in a satellite is presented

    Fostering a Healthy Food Culture: On Campus and Away

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    Liberal arts institutions have a unique opportunity to foster more responsible food systems. The lead panelists and other stakeholders in this session will share approaches for facilitating student engagement with food issues through academic, co-curricular and/or paraprofessional activities

    Inelastic Light Scattering Processes

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    Five different inelastic light scattering processes will be denoted by, ordinary Raman scattering (ORS), resonance Raman scattering (RRS), off-resonance fluorescence (ORF), resonance fluorescence (RF), and broad fluorescence (BF). A distinction between fluorescence (including ORF and RF) and Raman scattering (including ORS and RRS) will be made in terms of the number of intermediate molecular states which contribute significantly to the scattered amplitude, and not in terms of excited state lifetimes or virtual versus real processes. The theory of these processes will be reviewed, including the effects of pressure, laser wavelength, and laser spectral distribution on the scattered intensity. The application of these processes to the remote sensing of atmospheric pollutants will be discussed briefly. It will be pointed out that the poor sensitivity of the ORS technique cannot be increased by going toward resonance without also compromising the advantages it has over the RF technique. Experimental results on inelastic light scattering from I(sub 2) vapor will be presented. As a single longitudinal mode 5145 A argon-ion laser line was tuned away from an I(sub 2) absorption line, the scattering was observed to change from RF to ORF. The basis, of the distinction is the different pressure dependence of the scattered intensity. Nearly three orders of magnitude enhancement of the scattered intensity was measured in going from ORF to RF. Forty-seven overtones were observed and their relative intensities measured. The ORF cross section of I(sub 2) compared to the ORS cross section of N2 was found to be 3 x 10(exp 6), with I(sub 2) at its room temperature vapor pressure

    Postgraduate pedagogy in pandemic times: Online forums as facilitators of access to dialogic interaction and scholarly voices

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    In 2020, when the switch to remote teaching and learning required redesigning asynchronous on-line versions of face-to-face courses, we were concerned about whether access to engaged and dialogic learning could be facilitated in this new space. In attempting to address this concern we asked students in a B Ed Honours course to post, in an online forum, their reflective responses to weekly readings and to each other’s posts. This discussion forum became the engine of the course. With their permission, the posts of students in the 2021 cohort, together with their summative reflective reading response assignment, were analysed in order to understand different kinds of dialogic interactions and their affordances for reducing the potential alienation of asynchronous learning. One of the key findings that emerged from this analysis is the role of dialogic interaction in facilitating the development of personal, professional and scholarly voices which contributed to epistemic access.  Our analysis was informed by the theoretical work of Bakhtin on the dialogic and by theoretical and empirical work of scholars in the field of critical pedagogies. We use examples from the writing of a ‘stronger’ and a ‘weaker’ student to illustrate how students negotiated roles and positions for themselves by appropriating and using the textual resources available on the forum. We argue for the value of sustained practice in ‘writing about reading’, of reading each other’s writing and of ‘writing back’ to one another on-line, for the gradual acquisition of a range of confident voices and for enhanced understanding of module content

    New Experimental Limit on Photon Hidden-Sector Paraphoton Mixing

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    We report on the first results of a search for optical-wavelength photons mixing with hypothetical hidden-sector paraphotons in the mass range between 10^-5 and 10^-2 electron volts for a mixing parameter greater than 10^-7. This was a generation-regeneration experiment using the "light shining through a wall" technique in which regenerated photons are searched for downstream of an optical barrier that separates it from an upstream generation region. The new limits presented here are approximately three times more sensitive to this mixing than the best previous measurement. The present results indicate no evidence for photon-paraphoton mixing for the range of parameters investigated.Comment: 9 pages, 3 figure

    Anthelmintic and antimycobacterial activity of fractions and compounds isolated from Cissampelos mucronata

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    ETHNOPHARMACOLOGICAL RELEVANCE : Cissampelos mucronata A. Rich., a perennial climber belonging to the family Menispermaceae, has been used traditionally to treat parasites and tuberculosis-related symptoms. Co-infection of helminth parasites and tuberculosis-causing pathogens heightens the risk of developing active tuberculosis. AIM OF THE STUDY : The aim was to isolate and characterize antimycobacterial compounds from Cissampelos mucronata and to investigate their antibiofilm and anthelmintic efficacy as well as cytotoxicity. MATERIALS AND METHODS : The acetone extract of C. mucronata leaves and stems was fractionated by vacuum liquid chromatography using hexane, ethyl acetate, acetone and methanol:chloroform (3:7). Separation of the active ethyl acetate fraction by column and preparative thin layer chromatography led to the isolation and identification of five compounds using NMR and LC-MS, as well as GC-MS for non-polar compounds. The anthelmintic, antimycobacterial, antibiofilm, antioxidant and anti-inflammatory effects as well as cytotoxicity of the fractions and compounds were determined. RESULTS : The ethyl acetate fraction had the best antimycobacterial activity (MIC = 0.015–0.08 mg/ml). The fractions were relatively non-toxic to Vero cells (0.03–0.79 mg/ml) and had good anti-inflammatory and antibiofilm effects. Five compounds were identified as stigmasterol, hentriacontane, simiarenol, nonacosene and carbonic acid. Nonacosene had moderate anthelmintic effects but poor antimycobacterial activity (MIC = 0.375 mg/ml). Nonacosene and hentriacontane had good biofilm inhibitory effect (90–100%). CONCLUSIONS : This study reveals that C. mucronata is a potential source of promising compounds with a range of useful bioactivities that support its use in traditional medicine. Development of plant-based remedies may assist in reducing the impact of co-infections with helminth parasites and tuberculosis-causing mycobacteria.The University of South Africa, the University of Pretoria, the South African Medical Research Council and the National Research Foundation.http://www.elsevier.com/locate/jethpharmhj2023Paraclinical Science

    ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

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    This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in neuroscience, psychiatry, neurology, and genetics. Most ENIGMA WGs focus on specific psychiatric and neurological conditions, other WGs study normal variation due to sex and gender differences, or development and aging; still other WGs develop methodological pipelines and tools to facilitate harmonized analyses of "big data" (i.e., genetic and epigenetic data, multimodal MRI, and electroencephalography data). These international efforts have yielded the largest neuroimaging studies to date in schizophrenia, bipolar disorder, major depressive disorder, post-traumatic stress disorder, substance use disorders, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, autism spectrum disorders, epilepsy, and 22q11.2 deletion syndrome. More recent ENIGMA WGs have formed to study anxiety disorders, suicidal thoughts and behavior, sleep and insomnia, eating disorders, irritability, brain injury, antisocial personality and conduct disorder, and dissociative identity disorder. Here, we summarize the first decade of ENIGMA's activities and ongoing projects, and describe the successes and challenges encountered along the way. We highlight the advantages of collaborative large-scale coordinated data analyses for testing reproducibility and robustness of findings, offering the opportunity to identify brain systems involved in clinical syndromes across diverse samples and associated genetic, environmental, demographic, cognitive, and psychosocial factors
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