Brittle Creep Failure, Critical Behavior, and Time-to-Failure Prediction of Concrete under Uniaxial Compression

Understanding the time-dependent brittle deformation behavior of concrete as a main building material is fundamental for the lifetime prediction and engineering design. Herein, we present the experimental measures of brittle creep failure, critical behavior, and the dependence of time-to-failure, on the secondary creep rate of concrete under sustained uniaxial compression. A complete evolution process of creep failure is achieved. Three typical creep stages are observed, including the primary (decelerating), secondary (steady state creep regime), and tertiary creep (accelerating creep) stages. The time-to-failure shows sample-specificity although all samples exhibit a similar creep process. All specimens exhibit a critical power-law behavior with an exponent of −0.51 ± 0.06, approximately equal to the theoretical value of −1/2. All samples have a long-term secondary stage characterized by a constant strain rate that dominates the lifetime of a sample. The average creep rate expressed by the total creep strain over the lifetime (tf-t0) for each specimen shows a power-law dependence on the secondary creep rate with an exponent of −1. This could provide a clue to the prediction of the time-to-failure of concrete, based on the monitoring of the creep behavior at the steady stage

The silicon isotope composition of Ethmodiscus rexlaminated diatom mats from the tropical West Pacific: Implications for silicate cycling during the Last Glacial Maximum

The cause of massive blooms of Ethmodiscus rex laminated diatom mats (LDMs) in the eastern Philippine Sea (EPS) during the Last Glacial Maximum (LGM) remains uncertain. In order to better understand the mechanism of formation of E. rex LDMs from the perspective of dissolved silicon (DSi) utilization, we determined the silicon isotopic composition of single E. rex diatom frustules (δ30SiE. rex) from two sediment cores in the Parece Vela Basin of the EPS. In the study cores, δ30SiE. rex varies from −1.23‰ to −0.83‰ (average −1.04‰), a range that is atypical of marine diatom δ30Si and that corresponds to the lower limit of reported diatom δ30Si values of any age. A binary mixing model (upwelled silicon versus eolian silicon) accounting for silicon isotopic fractionation during DSi uptake by diatoms was constructed. The binary mixing model demonstrates that E. rex dominantly utilized DSi from eolian sources (i.e., Asian dust) with only minor contributions from upwelled seawater sources (i.e., advected from Subantarctic Mode Water, Antarctic Intermediate Water, or North Pacific Intermediate Water). E. rex utilized only ~24% of available DSi, indicating that surface waters of the EPS were eutrophic with respect to silicon during the LGM. Our results suggest that giant diatoms did not always use a buoyancy strategy to obtain nutrients from the deep nutrient pool, thus revising previously proposed models for the formation of E. rex LDMs

smoothness-constrained face photo-sketch synthesis using sparse representation

Face photo-sketch and sketch-photo synthesis have important usages in law enforcement. It is challenging to synthesize face sketches from photos because the drawing techniques and styles of artists' depictions are hard to be learned. To synthesize face photos from sketches is also hard due to its ill-posed nature. In order to avoid mosaic effects in the existed photo-sketch methods, we propose a smoothness-constrained photo-sketch synthesis method via sparse representation. The work is an extension of the previous work[1]. The method is modeled as the minimization of an energy function, a large scale convex optimization problem with l1-norm constraint. Since previous optimization methods are infeasible to solve our problem, we propose an iterative optimization approach, which decomposes the large scale optimization into a sequence of small scale optimizations and solve them iteratively to obtain the approximated optimal solution. The same synthesis strategy can be also used to synthesize photos from sketches. Experiments show its effectiveness. © 2012 ICPR Org Committee.Science Council of Japan; Information Processing Society of Japan (IPSJ); Inst. Electron., Inf. Commun. Eng. (IEICE) Inf. Syst. Soc. (ISS); Japan Society for the Promotion of Science (JSPS); The Telecommunications Advancement FoundationFace photo-sketch and sketch-photo synthesis have important usages in law enforcement. It is challenging to synthesize face sketches from photos because the drawing techniques and styles of artists' depictions are hard to be learned. To synthesize face photos from sketches is also hard due to its ill-posed nature. In order to avoid mosaic effects in the existed photo-sketch methods, we propose a smoothness-constrained photo-sketch synthesis method via sparse representation. The work is an extension of the previous work[1]. The method is modeled as the minimization of an energy function, a large scale convex optimization problem with l1-norm constraint. Since previous optimization methods are infeasible to solve our problem, we propose an iterative optimization approach, which decomposes the large scale optimization into a sequence of small scale optimizations and solve them iteratively to obtain the approximated optimal solution. The same synthesis strategy can be also used to synthesize photos from sketches. Experiments show its effectiveness. © 2012 ICPR Org Committee

self-calibration of hybrid central catadioptric and perspective cameras

Hybrid central catadioptric and perspective cameras are desired in practice, because the hybrid camera system can capture large field of view as well as high-resolution images. However, the calibration of the system is challenging due to heavy distortions in catadioptric cameras. In addition, previous calibration methods are only suitable for the camera system consisting of perspective cameras and catadioptric cameras with only parabolic mirrors, in which priors about the intrinsic parameters of perspective cameras are required. In this work, we provide a new approach to handle the problems. We show that if the hybrid camera system consists of at least two central catadioptric and one perspective cameras, both the intrinsic and extrinsic parameters of the system can be calibrated linearly without priors about intrinsic parameters of the perspective cameras, and the supported central catadioptric cameras of our method can be more generic. In this work, an approximated polynomial model is derived and used for rectification of catadioptric image. Firstly, with the epipolar geometry between the perspective and rectified catadioptric images, the distortion parameters of the polynomial model can be estimated linearly. Then a new method is proposed to estimate the intrinsic parameters of a central catadioptric camera with the parameters in the polynomial model, and hence the catadioptric cameras can be calibrated. Finally, a linear self-calibration method for the hybrid system is given with the calibrated catadioptric cameras. The main advantage of our method is that it cannot only calibrate both the intrinsic and extrinsic parameters of the hybrid camera system, but also simplify a traditional nonlinear self-calibration of perspective cameras to a linear process. Experiments show that our proposed method is robust and reliable. © 2012 Elsevier Inc. All rights reserved

Sex and age modify biochemical and skeletal manifestations of chronic hyperparathyroidism by altering target organ responses to Ca2+ and parathyroid hormone in mice.

We studied mice with or without heterozygous deletion of the Casr in the parathyroid gland (PTG) [(PTG) CaSR(+/-)] to delineate effects of age and sex on manifestations of hyperparathyroidism (HPT). In control mice, aging induced a left-shift in the Ca(2+) /parathyroid hormone (PTH) set point accompanied by increased PTG CaSR expression along with lowered serum Ca(2+) and mildly increased PTH levels, suggesting adaptive responses of PTGs to aging-induced changes in mineral homeostasis. The aging effects on Ca(2+) /PTH set point and CaSR expression were significantly blunted in (PTG) CaSR(+/-) mice, who showed instead progressively elevated PTH levels with age, especially in 12-month-old females. These 12-month-old knockout mice demonstrated resistance to their high PTH levels in that serum 1,25-dihydroxyvitamin D (1,25-D) levels and RNA expression of renal Cyp27b1 and expression of genes involved in Ca(2+) transport in kidney and intestine were unresponsive to the rising PTH levels. Such changes may promote negative Ca(2+) balance, which further exacerbate the HPT. Skeletal responses to HPT were age-, sex-, and site-dependent. In control mice of either sex, trabecular bone in the distal femur decreased whereas cortical bone in the tibiofibular junction increased with age. In male (PTG) CaSR(+/-) mice, anabolic actions of the elevated PTH levels seemed to protect against trabecular bone loss at ≥ 3 months of age at the expense of cortical bone loss. In contrast, HPT produced catabolic effects on trabecular bone and anabolic effects on cortical bone in 3-month-old females; but these effects reversed by 12 months, preserving trabecular bone in aging mice. We demonstrate that the CaSR plays a central role in the adaptive responses of parathyroid function to age-induced changes in mineral metabolism and in target organ responses to calciotropic hormones. Restraining the ability of the PTG to upregulate CaSRs by heterozygous gene deletion contributes to biochemical and skeletal manifestations of HPT, especially in aging females

Calcium-Sensing Receptors in Chondrocytes and Osteoblasts Are Required for Callus Maturation and Fracture Healing in Mice.

Calcium and its putative receptor (CaSR) control skeletal development by pacing chondrocyte differentiation and mediating osteoblast (OB) function during endochondral bone formation-an essential process recapitulated during fracture repair. Here, we delineated the role of the CaSR in mediating transition of callus chondrocytes into the OB lineage and subsequent bone formation at fracture sites and explored targeting CaSRs pharmacologically to enhance fracture repair. In chondrocytes cultured from soft calluses at a closed, unfixed fracture site, extracellular [Ca2+ ] and the allosteric CaSR agonist (NPS-R568) promoted terminal differentiation of resident cells and the attainment of an osteoblastic phenotype. Knockout (KO) of the Casr gene in chondrocytes lengthened the chondrogenic phase of fracture repair by increasing cell proliferation in soft calluses but retarded subsequent osteogenic activity in hard calluses. Tracing growth plate (GP) and callus chondrocytes that express Rosa26-tdTomato showed reduced chondrocyte transition into OBs (by >80%) in the spongiosa of the metaphysis and in hard calluses. In addition, KO of the Casr gene specifically in mature OBs suppressed osteogenic activity and mineralizing function in bony calluses. Importantly, in experiments using PTH (1-34) to enhance fracture healing, co-injection of NPS-R568 not only normalized the hypercalcemic side effects of intermittent PTH (1-34) treatment in mice but also produced synergistic osteoanabolic effects in calluses. These data indicate a functional role of CaSR in mediating chondrogenesis and osteogenesis in the fracture callus and the potential of CaSR agonism to facilitate fracture repair. © 2019 American Society for Bone and Mineral Research

Rapid precipitation changes in the tropical West Pacific linked to North Atlantic climate forcing during the last deglaciation

The cause of rapid hydrological changes in the tropical West Pacific during the last deglaciation remains controversial. In order to test whether these changes were triggered by abrupt climate change events in the North Atlantic Ocean, variations in precipitation during the last deglaciation (18–10 ka) were extracted from proxy records of chemical weathering and terrigenous input in the western Philippine Sea (WPS). The evolution of chemical weathering and terrigenous input since 27 ka was reconstructed using the chemical index of alteration (CIA), elemental ratios (K/Al, TOC/TN and Ti/Ca), δ13Corg, terrigenous fraction abundance and flux data from International Marine Global Change Study Program (IMAGES) core MD06-3054 collected on the upper continental slope of eastern Luzon (northern Philippines). Sediment deposited during the Last Glacial Maximum (LGM) shows weathering equal to or slightly greater than Holocene sediment in the WPS. This unusual state of chemical weathering, which is inconsistent with lower air temperatures and decreased precipitation in Luzon during the LGM, may be due to reworking of poorly consolidated sediments on the eastern Luzon continental shelf during the LGM sea-level lowstand. Rapid changes in chemical weathering, characterized by higher intensity during the Heinrich event 1 (H1) and Younger Dryas (YD) and lower intensity during the Bølling-Allerød (B/A), were linked to rapid variations in precipitation in the WPS during the last deglaciation. The higher terrigenous inputs during the LGM relative to those of the Holocene were controlled by sea-level changes rather than precipitation. The terrigenous inputs show a long-term decline during the last deglaciation, punctuated by brief spikes during the H1 and YD related to sea-level rises and rapid precipitation changes in the WPS, respectively. The proxy records of chemical weathering and terrigenous input from eastern Luzon suggest high rainfall during the H1 and YD events, consistent with inferred rainfall patterns based on Fe/Ca records from offshore Mindanao. Rapid precipitation changes in the WPS did not coincide with migrations of the Intertropical Convergence Zone (ITCZ) but, rather, were related to state shifts of the El Niño-Southern Oscillation (ENSO) during the last deglaciation. Based on proxy records and modeling results, we argue that the Atlantic meridional overturning circulation (AMOC) controlled rapid precipitation changes in the tropical West Pacific through zonal shifts of ENSO or meridional migration of the ITCZ during the last deglaciation. Our findings highlight the dominant role of the North Atlantic Ocean in the tropical hydrologic cycle during the last deglaciation