Análisis de falla de una mordaza de prensa de banco, tornillo elevador y tubo de transporte de amoniaco

En este proyecto se realizó el diagnostico de las fallas que se presentaron en una mordaza para prensa de banco, un tornillo elevador y un tubo de transporte para amoniaco. Para hacer esto, se realizó una inspección visual del objeto de estudio, con apoyo de técnicas de caracterización como la microscopia óptica y medición de dureza. Los análisis de las muestras tomadas ayudan a recopilar evidencias para aclarar el panorama general de la raíz de la falla. Después de estudiar la información recolectada, se concluye que la mordaza falló por fatiga ya que muestra una serie de huellas características de este tipo de fenómeno. El tornillo elevador falló debido a un esfuerzo a flexión ocasionando que se presentara una fractura frágil. Por último, el tubo para transporte de amoniaco falló por corrosión en forma de picaduras ocasionadas por el entorno al cual estaba expuesto. Esta clase de estudios ayuda a definir parámetros de diseño para evitar fallas en máquinas y estructuras, así como crear un historial de fallas con causas definidas que servirán como apoyo a futuros proyectos.In this project the diagnosis of the faults that were presented in a vice for the bench press, a lifting screw and a transport tube for ammonia was made. To do this, a visual inspection of the object of study was carried out, with the support of characterization techniques such as optical microscopy and hardness measurement. The analyzes of the samples help to gather evidence to clarify the general panorama of the root of the fault. After studying the information collected, it is concluded that the gag was due to fatigue and that it shows a series of traces characteristic of this type of phenomenon. The steel screw is due to a bending stress causing a brittle fracture to occur. Finally, the tube for the transport of ammonia was due to corrosion in the form of bites caused by the environment to which it was exposed. This type of studies helps to define design parameters to avoid faults in machines and structures, as well as create a history of failures with defined causes that serve as support for future project

A Domain-Adaptable Heterogeneous Information Integration Platform: Tourism and Biomedicine Domains.

In recent years, information integration systems have become very popular in mashup-type applications. Information sources are normally presented in an individual and unrelated fashion, and the development of new technologies to reduce the negative effects of information dispersion is needed. A major challenge is the integration and implementation of processing pipelines using different technologies promoting the emergence of advanced architectures capable of processing such a number of diverse sources. This paper describes a semantic domain-adaptable platform to integrate those sources and provide high-level functionalities, such as recommendations, shallow and deep natural language processing, text enrichment, and ontology standardization. Our proposed intelligent domain-adaptable platform (IDAP) has been implemented and tested in the tourism and biomedicine domains to demonstrate the adaptability, flexibility, modularity, and utility of the platform. Questionnaires, performance metrics, and A/B control groups’ evaluations have shown improvements when using IDAP in learning environmentspost-print2139 K

Light-induced capacitance tunability in ferroelectric crystals

The remote controlling of ferroic properties with light is nowadays a hot and highly appealing topic in materials science. Here, we shed light on some of the unresolved issues surrounding light–matter coupling in ferroelectrics. Our findings show that the capacitance and, consequently, its related intrinsic material property, i.e., the dielectric constant, can be reversibly adjusted through the light power control. High photodielectric performance is exhibited across a wide range of the visible light wavelength because of the wavelength-independence of the phenomenon. We have verified that this counterintuitive behavior can be strongly ascribed to the existence of “locally free charges” at domain wall.Postprint (author's final draft

Taxonomic identity of invasive rabbits in Cuba: first record of Eastern Cottontail, Sylvilagus floridanus (Mammalia: Lagomorpha)

In islands of the West Indian zoogeographical region, rabbits are not native, and wild populations are the result of introductions. Oryctolagus cuniculus is the only lagomorph listed among the introduced mammals of the Cuban archipelago. We analyzed specimens of wild rabbits and we report the occurrence of Sylvilagus floridanus for the first time in Cuba. Capture data suggest that their distribution is currently limited to the west-central region of the island. However, the niche models showed high climatic suitability throughout the majority of Cuba, suggesting a high expansion probability

Empresa social biosaludable de paneleros COOPANELA

El presente proyecto está denominado como Empresa Social Biosaludable de Paneleros – Coopanela el objetivo principal fue crear un modelo de negocio de emprendimiento social “Empresa social biosaludable de paneleros – COOPANELA” en el municipio de Convención, Norte de Santander, para dar solución a la problemática social y a la falta de empleo del sector. El proyecto social plantea la inversión en zonas vulnerables que permitan el desarrollo y sostenibilidad de la población. Se empleó la metodología por fases las cuales fueron: planeación, diseño y formulación, estrategia de mercado y marketing digital. Los resultados de la primera fase se identificaron problemática en la región de Convención (Norte de Santander), falta de oportunidades, crecimiento delictivo, pobreza. En la innovación social, creación de la Empresa Social biosaludable de paneleros – COOPANELA que generará empleos directos e indirectos. Para el Modelo Design Thinking empatiza realizando un auto-análisis para plantear posibles nuevas estrategias. Define los actores que intervienen en la conformación de la Empresa Social el recurso humano, agricultor, conductor, distribuidor, distribuidor al por menor, consumidor. En la idea negocio rentable y sostenible que beneficie a la sociedad de Convención (Norte de Santander), prototipo se escoge el producto. Durante la fase de Testea, se evolucionó la idea hasta convertirla en la solución que estábamos buscando.The present project is called the Paneleros Biosaludable Social Company - Coopanela. The main objective was to create a business model for social entrepreneurship "Paneleros Biosaludable Social Company - COOPANELA" in the municipality of Convencion, Norte de Santander, to provide a solution to the problem. social and the lack of employment in the sector. The social project proposes investment in vulnerable areas that requires the development and sustainability of the population. The methodology was used in phases, which were: planning, design and formulation, market strategy and digital marketing. The results of the first phase identified problems in the Convention region (Norte de Santander), lack of opportunities, criminal growth, poverty. In social innovation, creation of the biohealthy Social Company of paneleros - COOPANELA that generates direct and indirect jobs. For the Design Thinking Model, a self-analysis empathizes operations to propose possible new strategies. Define the actors involved in the formation of the Social Enterprise: the human resource, farmer, driver, distributor, retail distributor, consumer. In the idea of profitable and sustainable business that benefits the society of the Convention (Norte de Santander), the product is chosen as a prototype. During the Testea phase, the idea evolved to become the solution I could look for. During the marketing study of the social enterprise we developed COOPANELA, it develops new products; The secure distribution chain to the final consumer, the price between $1,684 to$ 1,662 in the first half of the year, with a distribution strategy, through channels that facilitate the transportation of the product. In the promotion, it is expected to sell a minimum 8% profit margin, while in the communication strategy, radio stations, two large pendulums, brochures, website; and publication of propaganda in a written medium, newspaper; The process, distribution and promotion service strategy is natural and artisanal, economic activity, biohealthy panela production, positioning strategy for benefits and with a transcendental message which would be: Do you want to take care of your health? internet and social media, online marketing has great advantages to offer

Erradicación de Helicobacter pylori mediante triple terapia (amoxicilina, claritromicina y omeprazole), en pacientes del Hospital Rafael Ángel Calderón Guardia

Artículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud. 2003Justificación y objetivo: H. pylori es un factor importante en el desarrollo de diversos tipos de patologías gástricas como: gastritis crónica, úlcera péptica, adenocarcinoma tipo intestinal y linfoma. Erradicar la infección es una importante posibilidad en la terapia de los pacientes con esas patologías. En el estudio se analizó la utilidad de la triple terapia para erradicar de la infección por H. pylori en pacientes con gastritis crónica y úlcera péptica. Métodos: Se incluyeron 267 pacientes que atendieron el Servicio de Gastroenteróloga del HCG, entre enero y mayo de 2000. La presencia de H. pylori fue determinada por ureasa rápida, cultivo y antígenos fecales específicos. Se determin6 la CIM de algunos aislamientos mediante la prueba de E-test. Los pacientes recibieron triple terapia con amoxicilina (1000 mg bid vo), claritromicina (500 mg bid vo - Claritrobac,) y omeprazole (20 mg bid vo - Proton,), por 10 días. La erradicación de la infección se definió como presencia de H. pylori al principio del tratamiento y un resultado negativo en la prueba de antígenos fecales específicos, entre 30 y 45 días después de finalizado el tratamiento. Resultados: De los 267 pacientes que recibieron la triple terapia, 189 (70,8%) la completaron. La erradicación de la bacteria se confirmó en 127 (84,7%) de los pacientes que completaron el tratamiento. Treinta y siete (94,9%) de los 39 pacientes con diagnóstico endoscópico de úlcera péptica erradicaron la bacteria. La erradicación fue exitosa incluso en pacientes portadores de cepas que mostraron resistencia in vitro a amoxicilina o a claritromicina, aunque en este estudio la presencia de cepas sensibles no predice el éxito del tratamiento en todos los casos. Conclusión: La-triple terapia basada en amoxicilina (1000 mg bid vo), claritromicina (500 mg bid vo - Claritrobac,) y omeprazole (20 mg bid. vo - Proton,), por 10 días, erradicó la infección por H. pylori en el 84,7% de los pacientes que cumplieron el tratamiento, incluyendo a 37 de 39 pacientes (94,9%) con enfermedad úlcero-péptica. La triple terapia por 10 días constituye una opción exitosa para erradicar de la infección por H. pylori.Universidad de Costa Rica. Instituto de Investigaciones en Salud.UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA

SYNTHESIS OF 1H-BENZOXAZINE-2,4-DIONES FROM HETEROCYCLIC ANHYDRIDES: EVALUATION OF ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES

A facile one-step synthesis of 1H-benzoxazine-2,4-diones from heterocyclic anhydrides and TMSA was described. This paper determines their antimicrobial activity against nine human bacterial pathogens by the broth microdilution method; antioxidant activity by DPPH• inactivation and a ferric-reducing power assay; and toxicity by a brine shrimp, Artemia salina, assay. The 1H-benzoxazine-2,4-dione yields were in the range of 57 to 98%. The novel compound 1H-pyrazino[2,3-][1,3]oxazine-2,4-dione 4c showed the highest antioxidant capacity (DPPH 35.4% and FRAP 0.063 µmol TEs/µmol)

Bronchoscopist's perception of the quality of the single-use bronchoscope (Ambu aScope4™) in selected bronchoscopies: a multicenter study in 21 Spanish pulmonology services

Background: The disposable bronchoscope is an excellent alternative to face the problem of SARS-CoV-2 and other cross infections, but the bronchoscopist’s perception of its quality has not been evaluated. Methods: To evaluate the quality of the Ambu-aScope4 disposable bronchoscope, we carried out a cross-sectional study in 21 Spanish pulmonology services. We use a standardized questionnaire completed by the bronchoscopists at the end of each bronchoscopy. The variables were described with absolute and relative frequencies, measures of cen‑ tral tendency and dispersion depending on their nature. The existence of learning curves was evaluated by CUSUM analysis. Results: The most frequent indications in 300 included bronchoscopies was bronchial aspiration in 69.3% and the median duration of these was 9.1 min. The route of entry was nasal in 47.2% and oral in 34.1%. The average score for ease of use, image, and aspiration quality was 80/100. All the planned techniques were performed in 94.9% and the bronchoscopist was satisfed in 96.6% of the bronchoscopies. They highlighted the portability and immediacy of the aScope4TM to start the procedure in 99.3%, the possibility of taking and storing images in 99.3%. The CUSUM analysis showed average scores>70/100 from the frst procedure and from the 9th procedure more than 80% of the scores exceeded the 80/100 score

Bronchoscopist's perception of the quality of the single-use bronchoscope (Ambu aScope4™) in selected bronchoscopies : a multicenter study in 21 Spanish pulmonology services

Background: The disposable bronchoscope is an excellent alternative to face the problem of SARS-CoV-2 and other cross infections, but the bronchoscopist's perception of its quality has not been evaluated. Methods: To evaluate the quality of the Ambu-aScope4 disposable bronchoscope, we carried out a cross-sectional study in 21 Spanish pulmonology services. We use a standardized questionnaire completed by the bronchoscopists at the end of each bronchoscopy. The variables were described with absolute and relative frequencies, measures of central tendency and dispersion depending on their nature. The existence of learning curves was evaluated by CUSUM analysis. Results: The most frequent indications in 300 included bronchoscopies was bronchial aspiration in 69.3% and the median duration of these was 9.1 min. The route of entry was nasal in 47.2% and oral in 34.1%. The average score for ease of use, image, and aspiration quality was 80/100. All the planned techniques were performed in 94.9% and the bronchoscopist was satisfied in 96.6% of the bronchoscopies. They highlighted the portability and immediacy of the aScope4TM to start the procedure in 99.3%, the possibility of taking and storing images in 99.3%. The CUSUM analysis showed average scores > 70/100 from the first procedure and from the 9th procedure more than 80% of the scores exceeded the 80/100 score. Conclusions: The aScope4™ scored well for ease of use, imaging, and aspiration. We found a learning curve with excellent scores from the 9th procedure. Bronchoscopists highlighted its portability, immediacy of use and the possibility of taking and storing images