Congenital insensitivity to pain with anhidrosis as a little prevalent disease. Updates for a comprehensive therapeutic approach

La ICD con anhidrosis está provocada por mutaciones del gen NTRK1 y se caracteriza por ausencia de dolor e incapacidad para sudar. Son importantes algunas consideraciones a tener en cuenta con respecto al manejo de pacientes en procedimientos anestésicos. Se plantea el abordaje terapéutico de los pacientes con ICD con anhidrosis, las principales evidencias científicas relacionadas con esta enfermedad, definir los problemas de salud de estos pacientes, estudiar cómo se lleva a cabo el diagnóstico de la misma y describir las diferentes precauciones a tener en cuenta ante procesos anestésicos. Se ha realizado una búsqueda bibliográfica entre los meses de diciembre y enero mediante diferentes bases de datos y fuentes documentales como: Pubmed, Cohcrane, LILACS y Cuiden, ORPHANET y el Registro Nacional de Enfermedades Raras. Se utilizaron repositorios como Google Scholar y SciELO. Se escogieron artículos redactados en Castellano o inglés y no superiores a los 5 años de antigüedad (a excepción de aquellos que contenían información para el objeto de estudio). Los registros se analizaron mediante la herramienta CASPe y atendieron a criterios de inclusión y exclusión para su selección. Las publicaciones escogidas se clasificaron en 2 categorías de análisis: La primera, en función de las manifestaciones, mutaciones y diagnóstico de la ICD con anhidrosis, y la segunda, relacionada con el manejo anestésico. El control de la temperatura corporal es importante ante procesos anestésicos. Además, se notifican nuevas mutaciones en el gen NTRK1, aunque aún queda mucho campo de investigación con respecto a esta enfermedad. La conclusión es que no existe un tratamiento para esta enfermedad por lo que el cuidado continuado de estos pacientes es de vital importancia, así como el aumento de estudios de casos que nos permitan ampliar nuestro conocimiento

The pilot project of the mineral collections from the University of Barcelona: An opportunity to create updated teaching material to be shared with other universities

The Mineralogy teaching collection from the University of Barcelona has proved to be a successful tool for students. The urge of its renewal to meet the necessities of modernCindustry brought the idea to replicate this collection in order to offer high quality teaching material to other universities worldwide. This project has led to an international collaboration aiming to enhance international solidarity among universities and make evident the importance of Mineralogy in Geology studies

Com trobar elements rars de la taula periòdica a Catalunya?

Hi ha molts mecanismes de concentració d'elements químics a partir de la seva dispersió geoquímica per tal de formar dipòsits minerals d'interès econòmic. La diversitat de processos geològics que han configurat el subsòl de Catalunya permet esperar una gran diversitat de recursos, molts d'ells explotats ja de fa segles. En aquest treball es discuteixen les possibilitats que alguns recursos d'elements rars, mai investigats en detall, es puguin trobar a Catalunya, i es conclou que hi ha recursos potencials en aquests elements formats per processos de fraccionament magmàtic, hidrotermal i supergènic

Com fer un article divulgatiu. Integrant coneixements i desenvolupant competències

Activitat dissenyada per proporcionar als estudiants uns fonaments clars per escriure bones memòries, informes o articles en el seu futur professional. Neix de la necessitat de millorar la seva competència comunicativa escrita, i es basa en la redacció conjunta (professors + estudiants de diferent nivell) d'un article divulgatiu, amb revisió externa, i en la seva posterior presentació i divulgació. Es pretén també fomentar la metodologia docent d'Aprenentatge-Servei (ApS) entre els estudiant

Global variations in diabetes mellitus based on fasting glucose and haemogloblin A1c

Fasting plasma glucose (FPG) and haemoglobin A1c (HbA1c) are both used to diagnose diabetes, but may identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening had elevated FPG, HbA1c, or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardised proportion of diabetes that was previously undiagnosed, and detected in survey screening, ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the agestandardised proportion who had elevated levels of both FPG and HbA1c was 29-39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global gap in diabetes diagnosis and surveillance.peer-reviewe

Factors that affect the consumption of nutritional supplements in elderly adults in users who go to the Botica Salud & Bienestar. Of the province of Barranca – Lima in the period february – march 2022

Los estudios han demostrado la utilidad de la administración de suplementos nutricionales en adultos mayores, con efectos positivos y reduce las complicaciones a la salud sin disminuir el consumo de alimentos diario. La edad media de los participantes fue de 63 años, con un rango de 60 a 79 años. El 70.2% de los adultos mayores manifestó no padecer ningún tipo de enfermedad crónica, signos de deterioro cognitivo o algún daño físico. El 88.3% indicó que viven en familia. El 97.9% considera beneficioso en su estado de salud, físico y emocional. El 62.8% si dejara de usar los suplementos nutricionales produciría desnutrición. El 28% indicó consumir suplementos nutricionales sin prescripción médicaStudies have demonstrated the usefulness of nutritional supplementation in older adults, with positive effects and reduced health complications without reducing daily food consumption. The mean age of the participants was 63 years, with a range of 60 to 79 years. 70.2% of the older adults stated that they did not suffer from any type of chronic disease, signs of cognitive impairment or any physical damage. 88.3% indicated that they live in a family. 97.9% considered it beneficial to their health, physical and emotional. 62.8% if they stopped using nutritional supplements it would lead to malnutrition. 28% indicated that they consume nutritional supplements without a medical prescription

Investigación educativa en las aulas de primaria

Reúne trabajos derivados de la experiencias de diversos docentes en educación primaria en los siguientes temas: Tecnología de Información y Comunicación, educación inclusiva, enseñanza de la música, educación física, enseñanza de la historia, acoso escolar, auto-evaluación, métodos de enseñanza, inteligencia emocional, percepción del alumno, marco cognitivo en comprensión lectora y comunicación escuela-familia

Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

: Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29-39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance

Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

International audienceAbstract Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) are both used to diagnose diabetes, but these measurements can identify different people as having diabetes. We used data from 117 population-based studies and quantified, in different world regions, the prevalence of diagnosed diabetes, and whether those who were previously undiagnosed and detected as having diabetes in survey screening, had elevated FPG, HbA1c or both. We developed prediction equations for estimating the probability that a person without previously diagnosed diabetes, and at a specific level of FPG, had elevated HbA1c, and vice versa. The age-standardized proportion of diabetes that was previously undiagnosed and detected in survey screening ranged from 30% in the high-income western region to 66% in south Asia. Among those with screen-detected diabetes with either test, the age-standardized proportion who had elevated levels of both FPG and HbA1c was 29–39% across regions; the remainder had discordant elevation of FPG or HbA1c. In most low- and middle-income regions, isolated elevated HbA1c was more common than isolated elevated FPG. In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence. Our prediction equations help allocate finite resources for measuring HbA1c to reduce the global shortfall in diabetes diagnosis and surveillance

Diminishing benefits of urban living for children and adolescents’ growth and development

Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified