A Holistic Approach

During my interview for the position of editor here at Civil War Book Review, the director, Leah Wood Jewett, described the United States Civil War Center and its publication as having the mission of promoting the multidisciplinary study of the United States Civil War. Throughout my inaugural...

A Convergence Of Contexts

Civil War Book Review has been through its fair share of changes and upheavals over this past year. Early last summer I began my tenure as the new editor. In the fall we learned that our publishing partner could no longer afford to fund our journal. A few months later it was decided that the ...

Writing The War

Two segments included in this issue of Civil War Book Review directly address the fact that the Civil War has been the focus of an enormous amount of literary and scholarly attention. In his Rediscovering Civil War Classics column, David Madden takes a look at The Unwritten War: American Writers ...

The Benefits Of Change

There is a debate circulating in literary and academic circles regarding publishing on the Internet. Many purists fear that web publishing will tarnish the sanctity of language and literature while the avant-garde is embracing the excitement of hypertext and new age information sharing. There are pl...

A New Beginning

On behalf of the previous editors, the U.S. Civil War Center, and myself I would like to thank Michael Zibart and the BookPage team for their commitment to this publication over the last few years. It is with regret, for both parties, that our publishing partnership has been dissolved. As most of ...

Cwbr Author Interview: Compelling Images Enhance Narrative Histories: Interview With William C. Davis

William C. Davis is the author or editor of more than 40 books on the Civil War and Southern history, as well as numerous documentary screenplays. He has served as historical consultant on various television and film productions. Davis has twice been nominated for the Pulitzer Prize in history and is currently professor of history at the Virginia Polytechnic Institute and State University. His most recent book, The Civil War in Photographs (Carlton 2002), served as the platform for this interview..

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms