Tasa de éxito subjetivo y objetivo en pacientes operados con cinta suburetral transobturatriz: ocho años de seguimiento

Indexación: Scopus; Scielo.Antecedentes: La Incontinencia Urinaria de Esfuerzo (IOE) representa el 50% de las incontinencias urinarias en la mujer, produciendo un gran impacto en su calidad de vida. Actualmente el TOT es una de las técnicas quirúrgicas más utilizadas para su tratamiento. Objetivos: Determinar la tasa de éxito objetiva y subjetiva de las pacientes operadas por IOE e incontinencia de orina mixta (IOM) mediante TOT, y determinar la tasa de complicaciones perioperatorias. Métodos: Se realizó un estudio retrospectivo de cohorte de 8 años de seguimiento, en el que se evaluó mediante anamnesis, examen físico y protocolos quirúrgicos la tasa de éxito objetivo y subjetivo del TOT. Resultados: La tasa de éxito objetivo y subjetivo fue 92% y 76% respectivamente. El 8,3% de las pacientes presentó alguna complicación y la tasa de exposición de malla fue de 1,2%. Conclusiones: El TOT es una excelente alternativa para el tratamiento de la IOE en el Hospital de Quilpué.http://ref.scielo.org/6tnxn

The social wellbeing of irrigation water. A demand-side integrated valuation in a Mediterranean agroecosystem

[EN] Irrigation water is a vital input for agricultural production. The supply of irrigation water to crops enhances land productivity and affects the agroecosystem functioning. Agroecosystems co-provide a wide range of agroecosystem services and disservices, which contribute positively and negatively, respectively, to human wellbeing. Therefore, irrigated agroecosystems produce several positive and negative outcomes in relation to society, and agricultural water management is key to the provision of adequate incentives for the enhancement of social wellbeing. In such a context, the aim of this work was to value the contribution of water to the provision of agroecosystem services and disservices, as a way to summarise the contribution of irrigation to social wellbeing. To this end, a demand-side integrated valuation of agroecosystem services and disservices was carried out for both rain-fed and irrigated agriculture in two different agroecosystems of the Region of Murcia (south-eastern Spain), a semi-arid western Mediterranean region characterised by water scarcity. In addition, the intensity of the agricultural water use was considered by distinguishing traditional and highly-intensive irrigated agroecosystems. Almond and lemon, two woody crops, were employed to develop the economic valuation in rain-fed and irrigated agroecosystems, respectively. The assessment of biophysical indicators to quantify the provision of services and disservices and their economic valuation, using market and non-market methods, were used. The results show that the contribution of water to social wellbeing is valued at 9000-12,300 euro/ha/year, being greater when the intensive use of agricultural water is promoted. The net economic value of all categories of agroecosystem services and disservices increases when irrigation water is supplied. Notwithstanding, the greatest contribution is due to the increase in provisioning services, mainly food provision in the case of the highly-intensive agroecosystem. Traditional irrigated agroecosystems make a greater contribution to regulating and cultural agroecosystem services. Hence, agricultural water management should focus on increasing the contribution of irrigated agroecosystems to human wellbeing.This work was supported by the AgriCambio project (Grant PID2020- 114576RB-I00 funded by MCIN/AEI/ 10.13039/501100011033). Jos¿e A. Zabala, Víctor Martínez-García and Jos¿e A. Albaladejo-García acknowledge the financial support from the Spanish Ministry of Education and Personal Training (FPU 16/03473; FPU19/05143; FPU 16/ 03562)Alcon, F.; Zabala, J.; Matínez-García, V.; Albaladejo, J.; López-Becerra, E.; De Miguel, MD.; Martínez-Paz, JM. (2022). The social wellbeing of irrigation water. A demand-side integrated valuation in a Mediterranean agroecosystem. Agricultural Water Management. 262. https://doi.org/10.1016/j.agwat.2021.10740026

Pruebas in vitro de respuesta plasmónica en nanopartículas de oro en el Parque Tecnológico del ITESO II

El PAP Pruebas in vitro de respuesta plasmónica en nanopartículas de oro en el Parque Tecnológico del ITESO II forma parte de un proyecto iniciado en el semestre de otoño del año 2019. En este proyecto se atendió la necesidad de desarrollar métodos novedosos y eficientes para la detección del virus del papiloma humano (VPH). El objetivo principal del proyecto consistió en evaluar el funcionamiento de un biosensor nanoestructurado para el reconocimiento del VPH de tipo 16 y 18, haciendo uso de nanopartículas de oro (AuNPs). Además, se plantearon tres objetivos específicos: Determinar la pureza del material genético del que se dispuso, inmovilizar sondas de tiol con las AuNPs y aumentar la concentración de AuNPs funcionalizadas en el acoplamiento con el material genético del VPH. Se utilizó la técnica de electroforesis para determinar la pureza del material genético de VPH con el que se trabajó. Por otro lado, se sintetizaron nanopartículas de oro utilizando el método de Turkevich y se funcionalizaron al adherirles sondas de tiol capaces de unirse a la proteína L I presente en el VPH. Se aprovechó el efecto plasmón de las nanopartículas funcionalizadas para detectar la presencia del material genético del virus a partir de un barrido espectrofotométrico.Los resultados demostraron diferencias en las absorbancias de los VPH del tipo 16 y 18. Los cambios en las concentraciones de material genético y AuNPs fueron claves para la obtención de resultados que resaltaran dichas diferencias. Se propone ajustar también las concentraciones de sondas para mejorar futuros resultados.ITESO, A.C

Obtaining protoanemonin through selective oxidation of Dfructose and 5-(hydroxymethyl) furfural in a self-catalysed reaction

Although different ways of converting 5- (hydroxymethyl)furfural (1) to various substrates with high value have been sought, few transformations have obtained building blocks that can be very useful in the area of fine chemistry. Herein, we report the synthesis of protoanemonin (5-methylenefuran-2(5H)- one) from D-fructose via compound (1), a versatile γalkylidenebutenolide, using an efficient self-catalysed process with formic acid, with high reaction performance and selectivity (up to 94% yield and 98% conversion from (1), while 28% yield from Dfructose). This efficient and simple operational process involved a two-phase aqueous-organic system between chlorinated solvents (CHxCly) and hydrogen peroxide as the initial oxidizing agent. The reaction presents a key cleavage in the 5-hydroxymethyl moiety of (1), due to the Baeyer-Villiger oxidation (BVO) process that generates formic acid in situ. Ultimately, DFF and HMF were successfully obtained in 80% and 98% yield, respectively, starting from D-fructose and using Preyssler heteropolyacids as Brønsted acid catalysts under an atmosphere of oxygen in the absence of hydrogen peroxide.Fil: Martínez, José J.. Universidad Pedagógica y Tecnológica de Colombia; ColombiaFil: Páez, Luis A.. Universidad Pedagógica y Tecnológica de Colombia; ColombiaFil: Gutiérrez, Luisa F.. Universidad Pedagógica y Tecnológica de Colombia; ColombiaFil: Pardo Cuervo, Oscar H.. Universidad Pedagógica y Tecnológica de Colombia; ColombiaFil: Rojas, Hugo A.. Universidad Pedagógica y Tecnológica de Colombia; ColombiaFil: Romanelli, Gustavo Pablo. Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de la Plata; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; ArgentinaFil: Portilla, Jaime. Universidad de Los Andes, Colombia; ColombiaFil: Castillo, Juan Carlos. Universidad Pedagógica y Tecnológica de Colombia; Colombia. Universidad de los Andes; ColombiaFil: Gamboa Becerra, Diana Paola. Universidad Pedagógica y Tecnológica de Colombia; Colombi

Global and Regional IUCN Red List Assessments: 3

In this contribution, the conservation status assessment of four vascular plants are presented according to IUCN categories and criteria. It includes the assessment at global level of Crepis lacera Ten subsp. titani (Pamp.) Roma-Marzio, G.Astuti & Peruzzi and Anthyllis hermanniae L. subsp. sicula Brullo & Giusso and the regional assessment of Commicarpus plumbagineus (Cav.) Standl. (Spain and Europe) and Ambrosia maritima L. (Italy)

VAMOS: a Pathfinder for the HAWC Gamma-Ray Observatory

VAMOS was a prototype detector built in 2011 at an altitude of 4100m a.s.l. in the state of Puebla, Mexico. The aim of VAMOS was to finalize the design, construction techniques and data acquisition system of the HAWC observatory. HAWC is an air-shower array currently under construction at the same site of VAMOS with the purpose to study the TeV sky. The VAMOS setup included six water Cherenkov detectors and two different data acquisition systems. It was in operation between October 2011 and May 2012 with an average live time of 30%. Besides the scientific verification purposes, the eight months of data were used to obtain the results presented in this paper: the detector response to the Forbush decrease of March 2012, and the analysis of possible emission, at energies above 30 GeV, for long gamma-ray bursts GRB111016B and GRB120328B.Comment: Accepted for pubblication in Astroparticle Physics Journal (20 pages, 10 figures). Corresponding authors: A.Marinelli and D.Zaboro

Contribución al conocimiento de los edafismos de las comarcas interiores de Andalucía Oriental (España)

In this paper we present 21 new records for 16 taxa of peculiar substrates in Eastern Andalusia; these evidences provide several new records for regional and provincial flora.Se presentan 21 citas de 16 taxones propios de substratos peculiares de Andalucía Oriental, estas citas aportan varias novedades florísticas regionales, provinciales y comarcales

Recommendations for the Treatment of Anti-Melanoma Differentiation-Associated Gene 5-positive Dermatomyositis-Associated Rapidly Progressive Interstitial Lung Disease

Objectives: The study aimed to develop evidence-based recommendations for the treatment of rapidly progressive interstitial lung disease (RPILD) associated with the anti-Melanoma Differentiation-Associated Gene 5-positive dermatomyositis (DM) syndrome. Methods: The task force comprised an expert panel of specialists in rheumatology, intensive care medicine, pulmonology, immunology, and internal medicine. The study was carried out in two phases: identifying key areas in the management of DM-RPILD syndrome and developing a set of recommendations based on a review of the available scientific evidence. Four specific questions focused on different treatment options were identified. Relevant publications in English, Spanish or French up to April 2018 were searched systematically for each topic using PubMed (MEDLINE), EMBASE, and Cochrane Library (Wiley Online). The experts used evidence obtained from these studies to develop recommendations. Results: A total of 134 studies met eligibility criteria and formed the evidentiary basis for the recommendations regarding immunosuppressive therapy and complementary treatments. Overall, there was general agreement on the initial use of combined immunosuppressive therapy. Combination of high-dose glucocorticoids and calcineurin antagonists with or without cyclophosphamide is the first choice. In the case of calcineurin antagonist contraindication or treatment failure, switching or adding other immunosuppressants may be individualized. Plasmapheresis, polymyxin B hemoperfusion and/or intravenous immunoglobulins may be used as rescue options. ECMO should be considered in life-threatening situations while waiting for a clinical response or as a bridge to lung transplant. Conclusions: Thirteen recommendations regarding the treatment of the anti-MDA5 positive DM-RPILD were developed using research-based evidence and expert opinion.This project was supported by Spanish Rheumatology Society and Spanish Society of Internal Medicine (GEAS, Study Group on Autoimmune Diseases)

Nueva citas para la flora de la provincia de Almería (Sureste Ibérico, España)

Three new floristic records are presented in this work including one new species for Andalucia (Tamarix dalmatica), one new species for the province of Almería (Filago hispanica) and a confirmation for this province (Orobanche ballotae).Se presentan tres citas florísticas que suponen, una novedad para Andalucía (Tamarix dalmatica), una novedad la provincia de Almería (Filago hispanica) y una confirmación para dicha provincia (Orobanche ballotae)

MAGIC Upper Limits for two Milagro-detected, Bright Fermi Sources in the Region of SNR G65.1+0.6

We report on the observation of the region around supernova remnant G65.1+0.6 with the stand-alone MAGIC-I telescope. This region hosts the two bright GeV gamma-ray sources 1FGL J1954.3+2836 and 1FGL J1958.6+2845. They are identified as GeV pulsars and both have a possible counterpart detected at about 35 TeV by the Milagro observatory. MAGIC collected 25.5 hours of good quality data, and found no significant emission in the range around 1 TeV. We therefore report differential flux upper limits, assuming the emission to be point-like (<0.1 deg) or within a radius of 0.3 deg. In the point-like scenario, the flux limits around 1 TeV are at the level of 3 % and 2 % of the Crab Nebula flux, for the two sources respectively. This implies that the Milagro emission is either extended over a much larger area than our point spread function, or it must be peaked at energies beyond 1 TeV, resulting in a photon index harder than 2.2 in the TeV band.Comment: 8 pages, 3 figures, 1 tabl