119 research outputs found

    Facebook: Friend or Foe? Exploring the Relationship Between Social Media Use, Social Comparison, Self-Esteem and Affect

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    Festinger’s social comparison theory suggests humans have a drive to gain accurate self-evaluations through comparison to others. As social media continues to expand, different platforms for social comparison are continuously being created allowing for individuals to compare themselves to millions of people worldwide. Social media provides the perfect platform for meticulous self-presentation. Frequent social media users may believe that others are happier and more successful than themselves, which could lead to lower self-esteem. Research also suggests that participants high in social comparison orientation seek out social comparisons on social media. Thus, an individual’s tendency to compare oneself to others may increase Facebook use and negatively affect their self-perception and mood. The purpose of this study was to analyze the relationships between social media use, social comparison orientation, self-esteem and affect. Participants (N=234) were recruited through Mechanical Turk and convenience sampling. Facebook use, social comparison orientation, self-esteem and affect were measured. It was hypothesized that individuals with higher social comparison orientation will use Facebook more frequently and that heavier Facebook use will be associated with lower self-esteem and greater negative affect. Gender differences were also examined, and it was expected that women would score higher than men on all variables. The results showed there is a relationship between social comparison orientation, affect and Facebook use. Facebook use was positively correlated with social comparison orientation and negative affect. No significant relationship was found between frequency of Facebook use and self-esteem. Women reported using Facebook more and engaging in more social comparison. The current findings increase our understanding of the correlations to Facebook use and suggests that there are important gender differences in social media use

    Influence de la dissipation énergetique sur l'efficacité de la flottation à air dissous : analogie avec la floculation

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    Les flottateurs Ă  air dissous sont classiquement dimensionnĂ©s Ă  partir de deux paramĂštres: le rapport mA/mS des masses d'air et de solides en prĂ©sence et le temps de contact entre phases. Une sĂ©rie d'essais effectuĂ©s sur cinq diffĂ©rentes unitĂ©s continues ou discontinues montre que ces seules variables opĂ©ratoires ne suffisent pas Ă  dĂ©terminer l'efficacitĂ©. De plus, l'extrapolation des donnĂ©es obtenues sur un floculateur discontinu conduirait Ă  des besoins en air dissous considĂ©rables pouvant limiter le dĂ©veloppement industriel. La dissipation d'Ă©nergie, habituellement nĂ©gligĂ©e, peut ĂȘtre quantifiĂ©e par le gradient de vitesse tel qu'il a Ă©tĂ© introduit en thĂ©orie de la floculation. De plus, une analogie entre la capture bulles-particules et le processus de floculation des particules primaires sur les flocs dĂ©jĂ  formĂ©s permet d'Ă©tendre les Ă©quations de vitesse de la floculation et d'obtenir un modĂšle cinĂ©tique oĂč interviennent seulement le gradient de vitesse et la concentration de particules; ce modĂšle remplace avantageusement l'approche classique qui considĂšre la flottation comme un processus du premier ordre par rapport aux particules. L'efficacitĂ© d'une cellule discontinue ou d'un floculateur piston est alors fonction du seul nombre de Camp. Les rĂ©sultats montrent l'existence d'un intervalle optimal pour le gradient de vitesse, 3000 Ă  4000 s-Âč, et pour le nombre de Camp 105 Ă  106. Le modĂšle devra ĂȘtre amĂ©liorĂ© par introduction de la tension critique de mouillage des particules.Dissolved air flotation units are generally designed on the basis of two parameters: the mA/mS ratio of the air mass to the solid mass in reaction, and the contact time between the gas phase and the solid phase. The insufficiency of this approach, which neglects energy dissipation, is demonstrated.Five units, the efficiencies of which were quantified by turbidimetry, were operated with a bentonite suspension previously flocculated with WAC or ferric chloride. Batch flotator 1 was a commercial unit designed to evaluate flotation feasibility (Fig.1). Flotators 2 and 3 were used to establish flotation efficiency as a function of the mA/mS ratio in continuous operation (Figs. 2 and 3). The influence of contact time was determined with batch flotator 4 (Fig. 4). Continuous flotators 3 and 5 were identical rectangular reactors but the latter was designed to allow the injection of pressurized water through five different points (Fig. 3).Turbidity abatement increases as a function of mA/mS, reaching a plateau, the curve having a classical sigmoidal shape in batch or in continuous operation (Fig. 5). However the important air requirement (mA/mS=1) to attain 70% abatement would hamper industrial applications. The contact time is the residence time of the gas phase through a batch cell or the residence time of the solid phase through a continuous flotator. Its influence is displayed in Fig. 6 where a sigmoidal curve shows that a 100 second contact time is required to reach a significant abatement even with a low mA/mS of 0.1. However, flotator 3 operated with a 108 second contact time and 0.1 mA/mS ratio afforded only 40% abatement (Fig. 7). Efficiency is not therefore determined by the two classical parameters only but also by energy dissipation. The energetic conditions can be quantified by velocity gradient measurements, of classical use in flocculation; this parameter is 3100 s-Âč in flotator 3 and between 590 and 1670 s-Âč in flotator 4.Flotation kinetics are classically considered first-order with respect to the particle concentration (Eqn. 3). In fact there is an analogy between flotation and flocculation which allows one to extend the well-known flocculation kinetics (Eqn. 4) to the flotation process (Eqn. 5). The steadiness of the bubble concentration permits the derivation of Eqn. 6, which enables one to calculate the efficiency of a batch or a plug-flow reactor as a function of the Camp number Gt (Eqn. 9). In fact there is an optimum range of velocity gradients between 3000 and 4000 s-Âč and an optimum range of Camp number between 105 and 106 (Fig. 9). The difference with the range currently observed in flocculation could be explained by the contact efficiencies in each process and by the probable existence of two ranges of optimal conditions. The model accuracy can be verified and the rate constant calculated (Figs. 8 and 10). This approach should be extended by testing particles exhibiting different degrees of hydrophobicity

    Revisiting the distribution of oceanic N<sub>2</sub> fixation and estimating diazotrophic contribution to marine production

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    Marine N2 fixation supports a significant portion of oceanic primary production by making N2 bioavailable to planktonic communities, in the process influencing atmosphere-ocean carbon fluxes and our global climate. However, the geographical distribution and controlling factors of marine N2 fixation remain elusive largely due to sparse observations. Here we present unprecedented high-resolution underway N2 fixation estimates across over 6000 kilometers of the western North Atlantic. Unexpectedly, we find increasing N2 fixation rates from the oligotrophic Sargasso Sea to North America coastal waters, driven primarily by cyanobacterial diazotrophs. N2 fixation is best correlated to phosphorus availability and chlorophyll-a concentration. Globally, intense N2 fixation activity in the coastal oceans is validated by a meta-analysis of published observations and we estimate the annual coastal N2 fixation flux to be 16.7 Tg N. This study broadens the biogeography of N2 fixation, highlights the interplay of regulating factors, and reveals thriving diazotrophic communities in coastal waters with potential significance to the global nitrogen and carbon cycles

    Role of small Rhizaria and diatoms in the pelagic silica production of the Sourther Ocean

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    We examined biogenic silica production and elementary composition (biogenic Si, particulate organic carbon and particulate organic nitrogen) of Rhizaria and diatoms in the upper 200 m along a transect in the Southwest Pacific sector of the Southern Ocean during austral summer (January–February 2019). From incubations using the 32Si radioisotope, silicic acid uptake rates were measured at 15 stations distributed in the Polar Front Zone, the Southern Antarctic Circumpolar Current and the Ross Sea Gyre. Rhizaria cells are heavily silicified (up to 7.6 nmol Si cell−1), displaying higher biogenic Si content than similar size specimens found in other areas of the global ocean, suggesting a higher degree of silicification of these organisms in the silicic acid rich Southern Ocean. Despite their high biogenic Si and carbon content, the Si/C molar ratio (average of 0.05 ± 0.03) is quite low compared to that of diatoms and relatively constant regardless of the environmental conditions. The direct measurements of Rhizaria's biogenic Si production (0.8–36.8 Όmol Si m−2 d−1) are of the same order of magnitude than previous indirect estimations, confirming the importance of the Southern Ocean for the global Rhizaria silica production. However, diatoms largely dominated the biogenic Si standing stock and production of the euphotic layer, with low rhizarians' abundances and biogenic Si production (no more than 1%). In this manuscript, we discuss the Antarctic paradox of Rhizaria, that is, the potential high accumulation rates of biogenic Si due to Rhizaria in siliceous sediments despite their low production rates in surface waters.VersiĂłn del editor3,38

    Revisiting the distribution of oceanic N 2 fixation and estimating diazotrophic contribution to marine production

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    Marine N 2 fixation supports a significant portion of oceanic primary production by making N 2 bioavailable to planktonic communities, in the process influencing atmosphere-ocean carbon fluxes and our global climate. However, the geographical distribution and controlling factors of marine N 2 fixation remain elusive largely due to sparse observations. Here we present unprecedented high-resolution underway N 2 fixation estimates across over 6000 kilometers of the western North Atlantic. Unexpectedly, we find increasing N 2 fixation rates from the oligotrophic Sargasso Sea to North America coastal waters, driven primarily by cyanobacterial diazotrophs. N 2 fixation is best correlated to phosphorus availability and chlorophyll-a concentration. Globally, intense N 2 fixation activity in the coastal oceans is validated by a meta-analysis of published observations and we estimate the annual coastal N 2 fixation flux to be 16.7 Tg N. This study broadens the biogeography of N 2 fixation, highlights the interplay of regulating factors, and reveals thriving diazotrophic communities in coastal waters with potential significance to the global nitrogen and carbon cycles

    Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure

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    Aims: Recent studies have demonstrated the importance of chromatin remodelling via histone acetylation/deacetylation for the control of cardiac gene expression. Specific histone deacetylases (HDACs) can, in fact, play a positive or negative role in determining cardiac myocyte (CM) size. Here, we report on the effect on hypertrophy development of three inhibitors (HDACi) of class I HDACs. Methods and results: The compounds were first analysed in vitro by scoring hypertrophy, expression of foetal genes, and apoptosis of neonatal rat CMs stimulated with phenylephrine, an \u3b11-adrenergic agonist. This initial screening indicated that a truncated derivative of apicidin with class I HDAC specificity, denoted API-D, had the highest efficacy to toxicity ratio, and was thus selected for further analysis in vivo. Administration of this drug significantly decreased myocardial hypertrophy and foetal gene expression after 1 week of pressure overload induced by thoracic aortic constriction (TAC) in mice. After 9 weeks of TAC, when manifest heart failure is encountered, mice treated with API-D presented with significantly improved echocardiographic and haemodynamic parameters of cardiac function when compared with untreated TAC-operated mice. Conclusion: The apicidin derivative, API-D, is capable of reducing hypertrophy and, consequently, the transition to heart failure in mice subjected to TAC. Treatment with this substance, therefore, holds promise as an important therapeutic option for heart failure

    Introduction to the French GEOTRACES North Atlantic Transect (GA01): GEOVIDE cruise

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    The GEOVIDE cruise, a collaborative project within the framework of the international GEOTRACES programme, was conducted along the French-led section in the North Atlantic Ocean (Section GA01), between 15 May and 30 June 2014. In this special issue (https://www.biogeosciences.net/special_issue900.html), results from GEOVIDE, including physical oceanography and trace element and isotope cyclings, are presented among 18 articles. Here, the scientific context, project objectives, and scientific strategy of GEOVIDE are provided, along with an overview of the main results from the articles published in the special issue

    Inactivation of CDK/pRb Pathway Normalizes Survival Pattern of Lymphoblasts Expressing the FTLD-Progranulin Mutation c.709-1G>A

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    8 figuras, 2 tablasBackground Mutations in the progranulin (PGRN) gene, leading to haploinsufficiency, cause familial frontotemporal lobar degeneration (FTLD-TDP), although the pathogenic mechanism of PGRN deficit is largely unknown. Allelic loss of PGRN was previously shown to increase the activity of cyclin-dependent kinase (CDK) CDK6/pRb pathway in lymphoblasts expressing the c.709-1G>A PGRN mutation. Since members of the CDK family appear to play a role in neurodegenerative disorders and in apoptotic death of neurons subjected to various insults, we investigated the role of CDK6/pRb in cell survival/death mechanisms following serum deprivation. Methodology/Principal Findings We performed a comparative study of cell viability after serum withdrawal of established lymphoblastoid cell lines from control and carriers of c.709-1G>A PGRN mutation, asymptomatic and FTLD-TDP diagnosed individuals. Our results suggest that the CDK6/pRb pathway is enhanced in the c.709-1G>A bearing lymphoblasts. Apparently, this feature allows PGRN-deficient cells to escape from serum withdrawal-induced apoptosis by decreasing the activity of executive caspases and lowering the dissipation of mitochondrial membrane potential and the release of cytochrome c from the mitochondria. Inhibitors of CDK6 expression levels like sodium butyrate or the CDK6 activity such as PD332991 were able to restore the vulnerability of lymphoblasts from FTLD-TDP patients to trophic factor withdrawal. Conclusion/Significance The use of PGRN-deficient lymphoblasts from FTLD-TDP patients may be a useful model to investigate cell biochemical aspects of this disease. It is suggested that CDK6 could be potentially a therapeutic target for the treatment of the FTLD-TDPThis work has been supported by grants from Ministry of Education and Science (SAF2007-61701, SAF2010-15700, SAF2011-28603), Fundación Eugenio Rodríguez Pascual, and Basque Government (Saiotek program 2008–2009). NE holds a fellowship of the JAE predoctoral program of the CSICPeer reviewe
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