El Parkinson no me detiene campaña de concientización de la enfermedad de Parkinson

Parkinson's Disease, after Alzheimer’s, is the second most common neurodegenerative disorder to appear. This disease is commonly associated with people from 65 years or older, however, recent studies have revealed the existence of Juvenile Parkinson’s presented in patients from 35 years. To date, Ecuador hasn’t developed studies to get official statistics on the incidence of Parkinson's. The following work consists in a research plan and an communicational initiative to encourage Parkinson's patients to remain active and to develop an equal society.La Enfermedad de Parkinson es el segundo trastorno neurodegenerativo más común en aparecer luego del Alzheimer. Hasta la fecha sus causas no han sido determinadas; sin embargo, estudios recientes han revelado la existencia del Parkinson Juvenil que se presenta a partir de los 35 años de edad. El Ecuador carece de cifras oficiales sobre la incidencia del Parkinson en la población, por lo que el trabajo presentado a continuación consiste en un plan de investigación e iniciativa comunicacional de impulso para que los pacientes con Parkinson sigan siendo entes activos de la sociedad y para que exista una sociedad más proactiva e informada

Auditoría de comunicación y campañas de comunicación internas y externas para el Colegio Johannes Kepler

The communication in the XXIst century has changed and transformed the development of the companies into the social area. The interpersonal and group relations not only appear in a daily ambience but also in a managerial ambience. Really for this reason the development of tactics and communicative strategies they will allow any individual to be able to interfere in a group or be a participant of the society who surrounds it...La comunicación en el siglo XXI ha cambiado y transformado el desarrollo de las empresas en el área social. Las relaciones interpersonales y grupales no solo se presentan en un ambiente cotidiano sino también en un ambiente empresarial. Es por esta razón que el desarrollo de tácticas y estrategias comunicativas permitirán que cualquier individuo pueda involucrarse en un grupo o ser partícipe de la sociedad que lo rodea..

Análisis de la diversidad genética de la población de toros Holstein Friesian importados al Ecuador entre los años 2000-2021.

Genetic diversity ensures the animal populations evolution and adaptation. Therefore assesing the genetic relationships, among others, imported and currently marketed bulls in Ecuador, through genealogical information, it is the research aim. As of digital and physical catalogs of bovine semen trading enterprises, it was used 273 bulls imported to Ecuador that are available, between the 2000-2021 years. It was got genealogical information for all Bulls up to four generations. For the flow and genetic relationships análisis, they were used information corresponding to name, international code (ID), country imported bull (DOB) and its ancestors birth date, both paternal (SIRE) and maternal (DAM), considering the queries in the ancestor origin countries databases, into four generations. It was assessed the ages, percentile value for net merit, the inbreeding by pedigree and genomics. The descriptive statistical análisis is performed by using the INFOSTAT program. The inbreeding coefficient and the average kinship with the ENDOG v4.8 program. Holstein Friesian genetics from the United States and Canada is responsible for 89.25% of the genetic flow to Ecuador. The assessed bulls average age was 8.50 years, assuming a generational interval between 6-8 years. Within the Ecuadorian market there is great proven Bulls in proof use, affecting the generation interval and genetic progress in comparison to the genomis bull´s, use. Regarding consanguinity, there is a high percentage index (20% - 13%) between the 2012 – 2016 years. In relation to net merit, the most the bulls are less than the 50th percentile, being the most used.ello, evaluar las relaciones genéticas entre toros importados y comercializados actualmente en el Ecuador mediante la información genealógica, constituye el objetivo de la investigación. A partir de catálogos digitales y físicos de las empresas comercializadoras de semen bovino se utilizaron 273 toros importados al Ecuador que se encuentran disponibles, entre los años 2000-2021. Se obtuvo la información genealógica de todos los toros hasta cuatro generaciones. Para el análisis del flujo y relaciones genéticas se utilizó información correspondiente a nombre, código internacional (ID), país, fecha de nacimiento del toro importado (DOB) y sus ancestros tanto paternos (SIRE) como maternos (DAM), considerando las consultas en las bases de datos de los países de origen de los ancestros, en 4 generaciones. Se evaluó las edades, el valor del percentil para mérito neto, la consanguinidad por pedigrí y genómica. El análisis estadístico descriptivo se realiza empleando el programa INFOSTAT. El coeficiente de consanguinidad y el parentesco medio con el programa ENDOG v4.8. La genética Holstein Friesian de Estados Unidos y Canadá es responsable en un 89.25% del flujo genético al Ecuador. La edad promedio de los toros evaluados fue de 8.50 años, presumiendo un intervalo generacional entre 6-8 años. Dentro del mercado ecuatoriano hay gran demanda de pajuelas de toros probados con alta confiabilidad, lo que implica el uso de toros de avanzada edad y toros en prueba, afectando al intervalo generacional y el progreso genético en comparación al uso de toros genómicos. Respecto a la consanguinidad existe un alto índice porcentual (20% - 13%) entre los años 2012 – 2016. En relación al mérito neto, la mayor parte de los toros están en menos del percentil 50, siendo los más utilizados

Aldea para niños en Quitumbe Arquitectura : potenciando los recursos naturales.

The village aims to get children abandoned on the streets, orphans and kids abused in their homes. Where to have a home and a mother who gives them love and affection. The village program contains public spaces, semi-public and private. Generating security and protection as well as training for these children. Each household has approximately 4-5 children having a completely private character. Workshops for learning and community use space with dining, game rooms and exhibition. A neighborhood library, workshops and public rental stores. The village seeks recovery and strengthening of the creek Shanshayaku, located in the parish Quitumbe as a closing of the existing broken branch. The lot has 15 500 square meters. The village will enhance the gorge by creating public space for the neighborhood parks and livable community.La aldea tiene como finalidad recibir niños abandonados en las calles, huérfanos y con maltrato en sus hogares. Donde tengan un hogar y una madre que les brinde cariño y afecto. El programa contenido en la aldea son espacios públicos, semipúblicos y privados. Generando seguridad y protección como también formación para estos niños. Cada hogar alberga aproximadamente de 4 a 5 niños teniendo un carácter completamente privado. Talleres de aprendizaje y un espacio de uso comunal con comedor, salas de juegos y exhibición semipúblicos. Una biblioteca barrial, talleres y almacenes de alquiler públicos. La aldea busca la recuperación y potenciación de la quebrada Shanshayaku, ubicada en la parroquia Quitumbe como un remate de la ramificación de quebradas existentes. El lote tiene 15 500 metros cuadrados. La aldea potenciara la quebrada por medio del espacio público generando parques habitables para el barrio y la comunidad

Weather Types Affect Rain Microstructure: Implications for Estimating Rain Rate

Quantitative precipitation estimation (QPE) through remote sensing has to take rain microstructure into consideration, because it influences the relationship between radar reflectivity Z and rain intensity R. For this reason, separate equations are used to estimate rain intensity of convective and stratiform rain types. Here, we investigate whether incorporating synoptic scale meteorology could yield further QPE improvements. Depending on large-scale weather types, variability in cloud condensation nuclei and the humidity content may lead to variation in rain microstructure. In a case study for Bavaria, we measured rain microstructure at ten locations with laser-based disdrometers, covering a combined 18,600 h of rain in a period of 36 months. Rain was classified on a temporal scale of one minute into convective and stratiform based on a machine learning model. Large-scale wind direction classes were on a daily scale to represent the synoptic weather types. Significant variations in rain microstructure parameters were evident not only for rain types, but also for wind direction classes. The main contrast was observed between westerly and easterly circulations, with the latter characterized by smaller average size of drops and a higher average concentration. This led to substantial variation in the parameters of the radar rain intensity retrieval equation Z-R. The e ect of wind direction on Z-R parameters was more pronounced for stratiform than convective rain types. We conclude that building separate Z-R retrieval equations for regional wind direction classes should improve radar-based QPE, especially for stratiform rain events

Bayesian analysis of the species-specific lengthening of the growing season in two European countries and the influence of an insect pest

A recent lengthening of the growing season in mid and higher latitudes of the northern hemisphere is reported as a clear indicator for climate change impacts. Using data from Germany (1951–2003) and Slovenia (1961–2004), we study whether changes in the start, end, and length of the growing season differ among four deciduous broad-leaved tree species and countries, how the changes are related to temperature changes, and what might be the confounding effects of an insect attack. The functional behaviour of the phenological and climatological time series and their trends are not analysed by linear regression, but by a new Bayesian approach taking into account different models for the functional description (one change-point, linear, constant models). We find advanced leaf unfolding in both countries with the same species order (oak > horse chestnut, beech, and birch). However, this advance is non linear over time and more apparent in Germany with clear change-points in the late 1970s, followed by marked advances (on average 3.67 days decade−1 in the 2000s). In Slovenia, we find a more gradual advance of onset dates (on average 0.8 days decade−1 in the 2000s). Leaf colouring of birch, beech, and oak has been slightly delayed in the last 3 decades, especially in Germany, however with no clear functional behaviour. Abrupt changes in leaf colouring dates of horse chestnut with recent advancing onset dates can be linked across countries to damage by a newly emerging pest, the horse chestnut leaf-miner (Cameraria ohridella). The lengthening of the growing season, more distinct in Germany than in Slovenia (on average 4.2 and 1.0 days decade−1 in the 2000s, respectively), exhibits the same species order in both countries (oak > birch > beech). Damage by horse chestnut leaf-miner leads to reduced lengthening (Germany) and drastic shortening (Slovenia) of the horse chestnut growing season (-12 days decade−1 in the 2000s). Advanced spring leaf unfolding and lengthening of the growing season of oak, beech and birch are highly significantly related to increasing March temperatures in both countries. Only beech and oak leaf unfolding in Germany, which is generally observed later in the year than that of the other two species, is more closely correlated with April temperatures, which comparably exhibit marked change-points at the end of the 1970s

Auditoria tributaria para el cumplimiento de las obligaciones tributarias de la “Empresa Fabrimetalicos Cesarin E.I.R.L.” periodo 2020 - Nuevo Chimbote

El presente trabajo de investigación tuvo como objetivo general; determinar el cumplimiento de las obligaciones tributarias mediante una auditoria tributaria en la empresa Fabrimetalicos Cesarin E.I.R.L., Nuevo Chimbote. El tipo de investigación es descriptiva y el diseño de investigación es no experimental. Por otra parte, la población estuvo conformada por todos los documentos relacionados con la obligación tributaria de la empresa Fabrimetalicos Cesarin E.I.R.L. Las técnicas e instrumentos utilizados fue la guía de entrevista. Se pudo concluir que la empresa “Fabrimetalicos Cesarin E.I.R.L,” no cumple de manera correcta con sus tributos, ya que, al momento de hacer las declaraciones correspondientes, no paga en los plazos establecidos, por lo que le genera atrasos, multas, notificaciones, entre otros, para ello se elaboró una propuesta de auditoría tributaria que le permita cumplir correctamente con las obligaciones tributarias respetando las normas y reglas que le ayudará a identificar los problemas, errores, omisiones, multas, que pueda tener la empresa

Stratiform and convective rain classification using machine learning models and micro rain radar

Rain type classification into convective and stratiform is an essential step required to improve quantitative precipitation estimations by remote sensing instruments. Previous studies with Micro Rain Radar (MRR) measurements and subjective rules have been performed to classify rain events. However, automating this process by using machine learning (ML) models provides the advantages of fast and reliable classification with the possibility to classify rain minute by minute. A total of 20,979 min of rain data measured by an MRR at Das in northeast Spain were used to build seven types of ML models for stratiform and convective rain type classification. The proposed classification models use a set of 22 parameters that summarize the reflectivity, the Doppler velocity, and the spectral width (SW) above and below the so-called separation level (SL). This level is defined as the level with the highest increase in Doppler velocity and corresponds with the bright band in stratiform rain. A pre-classification of the rain type for each minute based on the rain microstructure provided by the collocated disdrometer was performed. Our results indicate that complex ML models, particularly tree-based ensembles such as xgboost and random forest which capture the interactions of different features, perform better than simpler models. Applying methods from the field of interpretable ML, we identified reflectivity at the lowest layer and the average spectral width in the layers below SL as the most important features. High reflectivity and low SW values indicate a higher probability of convective rainPostprint (published version

Why do not pregnant women want to get vaccinated against the flu? : a scoping review

Fundamentos: Las mujeres embarazadas, los neonatos y los recién nacidos tienen mayor riesgo de complicaciones por la gri- pe estacional. La vacunación es efectiva y segura, pero hay baja adherencia en embarazadas. El objetivo de este trabajo fue iden- tificar los motivos que llevan a las embarazadas a no vacunarse contra la gripe estacional. Métodos: Scoping Review, en la que su utilizaron como tér- minos de búsqueda: DeCS “Mujeres Embarazadas”, “Vacunas contra la Influenza”. MeSH “Pregnant Women”, “Influenza Vac- cines”. Las bases de datos en las que se realizaron las búsquedas fueron: Medline, BVS, Scielo, CUIDEN. Se utilizó el modelo PRISMA y herramienta del Instituto Joanna Briggs para ordenar la búsqueda y sintetizar los resultados. Se identificaron los mo- tivos de no vacunación en cada estudio y se ordenaron según su frecuencia de aparición. Resultados: 16 estudios que identifican 15 motivos para no vacunarse. Los más frecuentes: Preocupación por los efectos secundarios y/o seguridad de la vacuna y falta de información/ recomendación por parte del personal sanitario. Conclusiones: La decisión para no vacunarse parece ser mul- tifactorial. En algunos motivos hallados el papel del profesional puede jugar un papel fundamental en la adherencia. Estos resul- tados podrían ser útiles para futuras investigaciones y pueden ser- vir de ejemplo para discusiones internas entre los profesionales sanitarios con el objetivo de promover la vacunación antigripal en embarazadas.Background: Pregnant women and newborns are at in- creased risk of complications from seasonal flu. Vaccination is effective and safe but there is low adherence in pregnant women. Objective: to identify the reasons that lead pregnant women not to be vaccinated against seasonal influenza. Methods: Scoping Review in which we used as search terms. DeCS “Pregnant Women”, “Vaccines against Influenza”. MeSH “Pregnant Women”, “Influenza Vaccines”, united by AND. Data- bases: Medline, VHL, Scielo, CUIDEN. The PRISMA model and the Joanna Briggs Institute tool were used to sort the search and synthesize the results. Motives were identified in each study and ordered according to frequency of appearance. Results: 16 studies were found that identify 15 reasons for not being vaccinated. The most frequent were: Concern about side effects and / or vaccine safety and lack of information / re- commendation from health professionals. Conclusions: The decision of not to be vaccinated seems to be multifactorial. In some cases, health professionals can play a fundamental role in adherence. These results could be useful for future research

Changes to Airborne Pollen Counts across Europe

A progressive global increase in the burden of allergic diseases has affected the industrialized world over the last half century and has been reported in the literature. The clinical evidence reveals a general increase in both incidence and prevalence of respiratory diseases, such as allergic rhinitis (common hay fever) and asthma. Such phenomena may be related not only to air pollution and changes in lifestyle, but also to an actual increase in airborne quantities of allergenic pollen. Experimental enhancements of carbon dioxide (CO2) have demonstrated changes in pollen amount and allergenicity, but this has rarely been shown in the wider environment. The present analysis of a continental-scale pollen data set reveals an increasing trend in the yearly amount of airborne pollen for many taxa in Europe, which is more pronounced in urban than semi-rural/rural areas. Climate change may contribute to these changes, however increased temperatures do not appear to be a major influencing factor. Instead, we suggest the anthropogenic rise of atmospheric CO2 levels may be influentia