Miners and mining in the Late Bronze Age: a multidisciplinary study from Austria

The extraction and processing of metal ores, particularly those of copper and tin, are regarded as among the principal motors of Bronze Age society. The skills and risks of mining lie behind the weapons, tools and symbols that drove political and ideological change. But we hear much less about the miners themselves and their position in society. Who were these people? Were they rich and special, or expendable members of a hard-pressed workforce? In this study the spotlight moves from the adits, slags and furnaces to the bones and seeds, providing a sketch of dedicated prehistoric labourers in their habitat. The Mauken miners were largely dependent on imported meat and cereals, and scarcely hunted or foraged the resources of the local forest. They seem to be the servants of a command economy, encouraged to keep their minds on the jo

Tolerability of inhaled N-chlorotaurine in an acute pig streptococcal lower airway inflammation model

<p>Abstract</p> <p>Background</p> <p>Inhalation of N-chlorotaurine (NCT), an endogenous new broad spectrum non-antibiotic anti-infective, has been shown to be very well tolerated in the pig model recently. In the present study, inhaled NCT was tested for tolerability and efficacy in the infected bronchopulmonary system using the same model.</p> <p>Methods</p> <p>Anesthetized pigs were inoculated with 20 ml of a solution containing approximately 10⁸CFU/ml <it>Streptococcus pyogenes </it>strain d68 via a duodenal tube placed through the tracheal tube down to the carina. Two hours later, 5 ml of 1% NCT aqueous solution (test group, n = 15) or 5 ml of 0.9% NaCl (control group, n = 16) was inhaled via the tracheal tube connected to a nebulizer. Inhalation was repeated every hour, four times in total. Lung function and haemodynamics were monitored. Bronchoalveolar lavage samples were removed for determination of colony forming units (CFU), and lung samples for histology.</p> <p>Results</p> <p>Arterial pressure of oxygen (PaO₂) decreased rapidly after instillation of the bacteria in all animals and showed only a slight further decrease at the end of the experiment without a difference between both groups. Pulmonary artery pressure increased to a peak 1-1.5 h after application of the bacteria, decreased in the following hour and remained constant during treatment, again similarly in both groups. Histology demonstrated granulocytic infiltration in the central parts of the lung, while this was absent in the periphery. Expression of TNF-alpha, IL-8, and haemoxygenase-1 in lung biopsies was similar in both groups. CFU counts in bronchoalveolar lavage came to 170 (10; 1388) CFU/ml (median and 25 and 75 percentiles) for the NCT treated pigs, and to 250 (10; 5.5 × 10⁵) CFU/ml for NaCl treated pigs (p = 0.4159).</p> <p>Conclusions</p> <p>Inhaled NCT at a concentration of 1% proved to be very well tolerated also in the infected bronchopulmonary system. This study confirms the tolerability in this delicate body region, which has been proven in healthy pigs previously. Regarding efficacy, no conclusions can be drawn, mainly because of the limited test period of the model.</p

Miners and mining in the Late Bronze Age : a multidisciplinary study from Austria

The extraction and processing of metal ores, particularly those of copper and tin, are regarded as among the principal motors of Bronze Age society. The skills and risks of mining lie behind the weapons, tools and symbols that drove political and ideological change. But we hear much less about the miners themselves and their position in society. Who were these people? Were they rich and special, or expendable members of a hardpressed workforce? In this study the spotlight moves from the adits, slags and furnaces to the bones and seeds, providing a sketch of dedicated prehistoric labourers in their habitat. The Mauken miners were largely dependent on imported meat and cereals, and scarcely hunted or foraged the resources of the local forest. They seem to be the servants of a command economy, encouraged to keep their minds on the job

O enquadramento das Missões de Paz (PKO) nas teorias da guerra e de polícia

A clareza original do que sejam as operações de manutenção, ou Missões de Paz - PKO - já não existe, se é que algum dia ela de fato existiu. No decorrer desse artigo Busca-se enquadrar as PKO nas teorias de guerra e de polícia, com base no entendimento sobre força e violência, uso da força, guerra e paz. Ao final, há algumas observações sobre a utilidade desses enquadramentos.<br>The original meaning of what are the Peacekeeping Operations - PKO - no longer exists, that is, if some day it really existed. This article tries to fit the PKO in the theories of war and police, based on the comprehension of strength and violence, the use of strength, war, and peace. In conclusion, there are some observations about the utility of those allocations