198 research outputs found
Thrombopoietin Receptor Agonists for Severe Thrombocytopenia after Allogeneic Stem Cell Transplantation : Experience of the Spanish Group of Hematopoietic Stem Cell Transplant
- Author
- Bastida J.M.
- Bento L.
- Bosch-Vilaseca Anna
- Cabrera R.
- Chinea A.
- De Miguel C.
- Duarte R.
- Espigado I.
- Fernández-Avilés Francesc
- Garcia Cadenas Irene
- García-Torres E.
- González-Porras J.R.
- Gutiérrez A.
- Herrera C.
- López J.
- Martínez-Muñoz M.E.
- Rivera D.
- Roldán Galvan Elisa
- Sampol A.
- Solano Carlos
- Universitat Autònoma de Barcelona
- Valcárcel David
- Vaz C.P.
- Yáñez L.
- Zudaire Teresa
- Publication venue
- Publication date
- 01/01/2019
- Field of study
Persistent thrombocytopenia is a common complication after allogeneic hematopoietic stem cell transplantation (allo-SCT). Romiplostim and eltrombopag are the currently available thrombopoietin receptor agonists (TPO-RAs), and some studies with very small numbers of cases have reported their potential efficacy in the allo-SCT setting. The present retrospective study evaluated the safety and efficacy of TPO-RAs in 86 patients with persistent thrombocytopenia after allo-HSCT. Sixteen patients (19%) had isolated thrombocytopenia (PT), and 71 (82%) had secondary failure of platelet recovery (SFPR). TPO-RA therapy was started at a median of 127 days (range, 27 to 1177 days) after allo-SCT. The median initial and maximum administered doses were 50 mg/day (range, 25 to 150 mg/day) and 75 mg/day (range, 25 to 150 mg/day), respectively, for eltrombopag and 1 µg/kg (range, 1 to 7 µg/kg) and 5 µg/kg (range, 1 to 10 µg/kg), respectively, for romiplostin. The median platelet count before initiation of TPO-RA therapy was 14,000/µL (range, 1000 to 57,000/µL). Platelet recovery to ≥50,000/µL without transfusion support was achieved in 72% of patients at a median time of 66 days (range, 2 to 247 days). Eighty-one percent of the patients had a decreased number of megakaryocytes before treatment, showing a slower response to therapy (P =.011). The median duration of treatment was 62 days (range, 7 to 700 days). Grade 3-4 adverse events (hepatic and asthenia) were observed in only 2% of the patients. At last follow-up, 81% of patients had discontinued TPO-RAs and maintained response, and 71% were alive. To our knowledge, this is the largest series analyzing the use of TPO-RAs after allo-SCT reported to date. Our results support the efficacy and safety in this new setting. Further prospective trials are needed to increase the level of evidence and to identify predictors of response
SARS-CoV-2 viral load in nasopharyngeal swabs is not an independent predictor of unfavorable outcome
- Author
- Aguilar-Guisado Manuela
- Aguilera A.
- Aguilera C.
- Aldabo-Pallas T.
- Alfaro-Lara V.
- Amaya Rosario
- Amodeo C.
- Ampuero J.
- Asensio M.
- Avilés M.D.
- Barrera-Pulido L.
- Barón-Franco B.
- Bellido-Alba R.
- Benjumea A.S.
- Berastegui-Cabrera Judith
- Bernabeu-Wittel M.
- Bueno Claudio
- Caballero-Eraso C.
- Cabrera M.
- Calderón E.
- Camacho-Martínez Pedro
- Carbajal-Guerrero J.
- Carretero-Ledesma Marta
- Cid-Cumplido M.
- Cisneros José Miguel
- Corcia-Palomo Y.
- Cordero Elisa
- Crespo-Rivas Juan Carlos
- de Azua Z.R.
- Delgado J.
- Deniz A.
- Domínguez-Petit A.
- Dusseck-Brutus R.
- Escoresca-Ortega A.
- Espinosa F.
- Espinosa N.
- Espinoza M.
- Ferrer M.
- Ferrer T.
- Ferrándiz-Millón C.
- Gallego-Texeira I.
- García E.
- García-Delgado H.
- García-Gutiérrez M.
- Gascón-Castillo M.L.
- González D.
- González-Estrada A.
- González-León R.
- Grande-Cabrerizo C.
- Gutiérrez S.
- Gámez-Mancera R.
- Gómez-González C.
- Hernández-Quiles C.
- Herrera-Melero I.C.
- Herrero-Romero M.
- Infante-Domínguez Carmen
- Jara L.
- Jiménez-Jorge S.
- Jiménez-Juan C.
- Jiménez-Sánchez M.
- Lanseros-Tenllado J.
- Lepe José Antonio
- Lomas José Manuel
- Luque-Márquez R.
- López C.
- López I.
- López-Barrios Á.
- López-Cortés L.F.
- Macías-García D.
- Martín-Gutiérrez G.
- Martín-Villén L.
- Molina J.
- Morillo A.
- Márquez Eduardo
- Navarro-Amuedo M.D.
- Nieto-Martín D.
- Ortega F.
- Pachón Jerónimo
- Paniagua-García M.
- Peña-Rodgíuez A.
- Poyato M.
- Praena-Segovia J.
- Pérez E.
- Roca-Oporto C.
- Rodríguez J.F.
- Rodríguez-Hernández M.J.
- Rodríguez-Suárez S.
- Rodríguez-Villodres Á.
- Romero-Rodríguez N.
- Ruiz R.
- Ríos R.
- Salamanca C.
- Salto-Alejandre Sonsoles
- Sotomayor C.
- Sánchez S.
- Sánchez-Céspedes Javier
- Sánchez-Montagut V.M.
- Toral J.
- Publication venue
- Publication date
- 01/01/2021
- Field of study
The aim was to assess the ability of nasopharyngeal SARS-CoV-2 viral load at first patient’s hospital evaluation to predict unfavorable outcomes. We conducted a prospective cohort study including 321 adult patients with confirmed COVID-19 through RT-PCR in nasopharyngeal swabs. Quantitative Synthetic SARS-CoV-2 RNA cycle threshold values were used to calculate the viral load in log10 copies/mL. Disease severity at the end of follow up was categorized into mild, moderate, and severe. Primary endpoint was a composite of intensive care unit (ICU) admission and/or death (n = 85, 26.4%). Univariable and multivariable logistic regression analyses were performed. Nasopharyngeal SARS-CoV-2 viral load over the second quartile (≥ 7.35 log10 copies/mL, p = 0.003) and second tertile (≥ 8.27 log10 copies/mL, p = 0.01) were associated to unfavorable outcome in the unadjusted logistic regression analysis. However, in the final multivariable analysis, viral load was not independently associated with an unfavorable outcome. Five predictors were independently associated with increased odds of ICU admission and/or death: age ≥ 70 years, SpO2, neutrophils > 7.5 × 103/µL, lactate dehydrogenase ≥ 300 U/L, and C-reactive protein ≥ 100 mg/L. In summary, nasopharyngeal SARS-CoV-2 viral load on admission is generally high in patients with COVID-19, regardless of illness severity, but it cannot be used as an independent predictor of unfavorable clinical outcome
Epidemiological trends of HIV/HCV coinfection in Spain, 2015-2019
- Author
- Alcaráz A.
- Aldámiz-Echevarría T
- Alonso G.
- Arazo P.
- Armiñanzas Carlos
- Armiñanzas Carlos
- Arnalich F.
- Arponen S.
- Arranz A.
- Arribas J. R.
- Artero Arturo
- Artero Arturo
- Azkune H.
- Baraia J.
- Barrufet P.
- Berenguer J.
- Berenguer Juan
- Bernal E.
- Bernardino J.I.
- Bisbal O.
- Bisbe J.
- Blanes M.
- Boix Vicente
- Brieva T.
- Busca Carmen
- Busca Carmen
- Calabuig Eva
- Camacho A.
- Campoamor M.
- Cano A.
- Carmena J.
- Carmona M.P.
- Carretero S.
- Casado J.L.
- Casas E.
- Castellano A.
- Chamarro E.
- Chocarro A.
- Cifuentes C.
- Cifuentes Carmen
- Crespo M.
- Cuellar S.
- de la Fuente Belén
- de la Fuente Belén
- de la Peña M.
- De Lagarde M.
- de Miguel J.
- De Miguel Marta
- Del Romero J.
- Delgado A.
- Domingo Pere
- Domínguez L.
- Domínguez Lourdes
- Díez C.
- Díez M.
- Echevarría S.
- Egea I.
- Escrig C.
- Esteban M.C.
- Estrada V.
- Fanciulli C.
- Fanciulli Chiara
- Fariñas C.
- Fernández I.
- Fernández J.
- Ferrer A.
- Ferrero O.L.
- Ferrero Oscar L.
- Force L.
- Force Luis
- Galindo María José
- Galindo María José
- García C.
- García Coral
- García L.
- Gaspar G.
- Gaspar Gabriel
- Geijo P.
- Gimeno A.
- Giner L.
- Giner Livia
- Goenaga M.A.
- González Garcia Juan
- González-García J.
- Guardiola J.M.
- Gutiérrez I.
- Gutiérrez M.
- Gutiérrez-Cuadra M.
- Hernando A.
- Hernández-Quero J.
- Hervás R.
- Hontañón V.
- Ibarguren M.
- Ibarra S.
- Iribarren J.A.
- Iribarren José A.
- Jarrín I.
- Jarrín Inmaculada
- Lara G.
- Losa J.E.
- Losa Juan E.
- López I.
- López J.C.
- López-Aldeguer J.
- Machuca I.
- Manzardo Christian
- Martín-Carbonero M.L.
- Martínez-Alfaro Elisa
- Matarranz M.
- Mateo G.
- Merino E.
- Micán R.
- Miralles C.
- Montejano R.
- Montero M.
- Montero Marta
- Montero-Martínez Carmen Cecilia Ordoñez
- Montes M.L.
- Morano L.
- Morano Luis
- Moreno A.
- Moreno J.
- Moreno Javier
- Moreno L.
- Moreno S.
- Moreno V.
- Muñoz A.
- Muñoz J.
- Muñoz J.
- Muñoz L.
- Márquez M.
- Navarro C.
- Navarro J.
- Navarro Jordi
- Nuño E.
- Núñez M.J.
- Ocampo A.
- Orti A.J.
- Oteo J.A.
- Padilla B.
- Palacios R.
- Pampliega M.
- Peláez A.I.
- Peraire J.
- Piera-Rojo G.
- Planas B.
- Portilla I.
- Portilla J.
- Prado-González E.
- Puerta T.
- Pulido F.
- Pérez L.
- Pérez Laura
- Pérez-Elías M.J.
- Pérez-Latorre L.
- Pérez-Valero I.
- Quereda C.
- Ramírez M.
- Raposo M.
- Reus S.
- Rivero-Juárez A.
- Rivero-Román A.
- Rivero-Román Antonio
- Rodrigo M.
- Rodríguez C.
- Rodríguez Carmen
- Rodríguez-Arrondo F.
- Rubio R.
- Ruiz J.
- Salavert M.
- Santos I.
- Santos Ignacio
- Santos J.
- Santos Jesús
- Sanz J.
- Sanz J.
- Sanz José
- Silvariño R.
- Tasias M.
- Teira R.
- Tejerina F.
- Toledo C.
- Torrella A.
- Torrús D.
- Tuya M.J.
- Téllez M.J.
- Téllez María J.
- Valencia E.
- Vargas M.
- Vegas A.
- Velasco M.
- Veloso S.
- Veloso Sergio
- Vera M.
- Vergas J.
- Vidal F.
- Viladés C.
- Vilaró J.
- Vinuesa D.
- Vivancos M.J.
- Vivancos María J.
- Von Wichmann M.A.
- Zubero Z.
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Altres ajuts: Spanish AIDS Research Network; European Funding for Regional Development (FEDER).Objectives: We assessed the prevalence of anti-hepatitis C virus (HCV) antibodies and active HCV infection (HCV-RNA-positive) in people living with HIV (PLWH) in Spain in 2019 and compared the results with those of four similar studies performed during 2015-2018. Methods: The study was performed in 41 centres. Sample size was estimated for an accuracy of 1%. Patients were selected by random sampling with proportional allocation. Results: The reference population comprised 41 973 PLWH, and the sample size was 1325. HCV serostatus was known in 1316 PLWH (99.3%), of whom 376 (28.6%) were HCV antibody (Ab)-positive (78.7% were prior injection drug users); 29 were HCV-RNA-positive (2.2%). Of the 29 HCV-RNA-positive PLWH, infection was chronic in 24, it was acute/recent in one, and it was of unknown duration in four. Cirrhosis was present in 71 (5.4%) PLWH overall, three (10.3%) HCV-RNA-positive patients and 68 (23.4%) of those who cleared HCV after anti-HCV therapy (p = 0.04). The prevalence of anti-HCV antibodies decreased steadily from 37.7% in 2015 to 28.6% in 2019 (p < 0.001); the prevalence of active HCV infection decreased from 22.1% in 2015 to 2.2% in 2019 (p < 0.001). Uptake of anti-HCV treatment increased from 53.9% in 2015 to 95.0% in 2019 (p < 0.001). Conclusions: In Spain, the prevalence of active HCV infection among PLWH at the end of 2019 was 2.2%, i.e. 90.0% lower than in 2015. Increased exposure to DAAs was probably the main reason for this sharp reduction. Despite the high coverage of treatment with direct-acting antiviral agents, HCV-related cirrhosis remains significant in this population
Patient preferences and treatment safety for uncomplicated vulvovaginal candidiasis in primary health care
- Author
- A Spinillo
- A van Wersch
- Alicia Simón Fernández
- AM van Heusden
- AM van Heusden
- Ana I González González
- Ana Pastor Rodríguez-Moñino
- Ana Rey López
- BD Reed
- Beatriz López Uriarte
- Blanca Gutiérrez Teira
- C Calderón Gómez
- CA Rodgers
- Carmen Carballo
- Cristina De-Alba Romero
- Dolores Martínez López
- Elisa Ceresuela Wiesmann
- Evidence-Based Medicine Working Group
- F Garcia de Blas Gonzalez
- Fernanda Morales
- Fernando Gallardo Alonso
- Francisca García-de-Blas González
- GE Stein
- GE Stein
- H Timonen
- H Timonen
- Isabel Del-Cura González
- J das Neves
- J Martin-Fernandez
- J Pinto
- JD Sobel
- JD Sobel
- JD Sobel
- Jeannet Sánchez Yepes
- Jesús Fernández Horcajuelo
- Jesús Martín Fernández
- JM Tobin
- JS Bingham
- Justo M Del-Alamo Rodríguez
- Laura Balsalobre Arenas
- LO Eckert
- LO Eckert
- LS Seidman
- M del Canto De-Hoyos Alonso
- M José Iglesias Piñeiro
- M Nurbhai
- Marta Sánchez-Celaya del Pozo
- María J Rojas Giraldo
- MB Slavin
- ME Egan
- OO Adetoro
- Paulino Cubero González
- PG Pappas
- Ricardo Rodríguez Barrientos
- Rocío A Vello Cuadrado
- Rosa A Escriva Ferrairo
- S Fosch
- S Osser
- Sociedad Española de Medicina de Familia y Comunitaria
- Susana Tudanca Hernández
- Teresa Sanz Cuesta
- VM Montori
- Yolanda Ginés Díaz
- Yolanda Hernando Sanz
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>Vaginitis is a common complaint in primary care. In uncomplicated candidal vaginitis, there are no differences in effectiveness between oral or vaginal treatment. Some studies describe that the preferred treatment is the oral one, but a Cochrane's review points out inconsistencies associated with the report of the preferred way that limit the use of such data. Risk factors associated with recurrent vulvovaginal candidiasis still remain controversial.</p> <p>Methods/Design</p> <p>This work describes a protocol of a multicentric prospective observational study with one year follow up, to describe the women's reasons and preferences to choose the way of administration (oral vs topical) in the treatment of not complicated candidal vaginitis. The number of women required is 765, they are chosen by consecutive sampling. All of whom are aged 16 and over with vaginal discharge and/or vaginal pruritus, diagnosed with not complicated vulvovaginitis in Primary Care in Madrid.</p> <p>The main outcome variable is the preferences of the patients in treatment choice; secondary outcome variables are time to symptoms relief and adverse reactions and the frequency of recurrent vulvovaginitis and the risk factors. In the statistical analysis, for the main objective will be descriptive for each of the variables, bivariant analysis and multivariate analysis (logistic regression).. The dependent variable being the type of treatment chosen (oral or topical) and the independent, the variables that after bivariant analysis, have been associated to the treatment preference.</p> <p>Discussion</p> <p>Clinical decisions, recommendations, and practice guidelines must not only attend to the best available evidence, but also to the values and preferences of the informed patient.</p
Strategies to reengage patients lost to follow up in HIV care in high income countries, a scoping review
- Author
- Abdulghani N.
- Aceiton Jordi
- Almuedo Riera Alex
- Ambrosioni J.
- Amengual M. J.
- Barrufet Pilar M.
- Blanco J. L.
- Bruguera Andreu
- Burgos J.
- Cairó Mireia
- Calzado S.
- Campins Antoni
- Casabona Jordi
- Cervantes M.
- Chamarro E.
- Chivite Ivan
- Cifuentes Carmen
- Clotet i Sala Bonaventura
- Comella T.
- Cortés C.
- Curran Adrian
- Dalmau D.
- Diaz Yesika
- Domingo Pere (Domingo Pedrol)
- Escrig C.
- Falcó Vicenç
- Fanjul Francisco
- Ferrés M.
- Font R.
- Force Lluís
- Garcia Alcaide F.
- García Gasalla M.
- Gargoulas F.
- Giralt D.
- Gonzalez E.
- Gracia Mateo María
- Gurgui Ferrer Mercedes
- Gutiérrez Maria del Mar
- Hernandez Juanse
- Homar Borràs Francesc
- Imaz Arkaitz
- Jaén Angels
- Jou A.
- Laguno M.
- Lazzari Elisa de
- Leon E.
- Leyes M.
- Llibre Josep María
- Mallolas Masferrer Josep
- Manzardo Christian
- Martin L.
- Martinez Lacasa X.
- Martínez E.
- Martínez M.
- Masabeu Àngels
- Meyer Sebastián
- Miró Josep M.
- Morell B.
- Moreno Sergio
- Muntada Esteve
- Murillas Angoiti Javier
- Navarro Bernabé Joan
- Navarro G.
- Navarro M.
- Ortí Llaveria Amat
- Palacio Vieira Jorge
- Payeras T.
- Peraire Joaquim
- Peñaranda María
- Picis Study Group
- Podzamczer Palter Daniel
- Prieto P.
- Raventós B.
- Reyes Urueña Juliana Maria
- Ribas Maria Àngels
- Ribera Esteban
- Riera Melchor
- Rubia J. C.
- Saumoy Maria
- Segura F.
- Silva A.
- Tamayo M.
- Tiraboschi Juan Manuel
- Vanrell T.
- Vargas Montserrat
- Vidal Francesc
- Viladés Consuelo
- Vilaró Ingrid
- Vilchez H.
- Vilà J.
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 16/09/2021
- Field of study
Background: Despite remarkable achievements in antiretroviral therapy (ART), losses to follow-up (LTFU) might prevent the long-term success of HIV treatment and might delay the achievement of the 90-90-90 objectives. This scoping review is aimed at the description and analysis of the strategies used in high-income countries to reengage LTFU in HIV care, their implementation and impact. Methods: A scoping review was done following Arksey & O'Malley's methodological framework and recommendations from Joanna Briggs Institute. Peer reviewed articles were searched for in Pubmed, Scopus and Web of Science; and grey literature was searched for in Google and other sources of information. Documents were charted according to the information presented on LTFU, the reengagement procedures used in HIV units in high-income countries, published during the last 15 years. In addition, bibliographies of chosen articles were reviewed for additional articles. Results: Twenty-eight documents were finally included, over 80% of them published in the United States later than 2015. Database searches, phone calls and/or mail contacts were the most common strategies used to locate and track LTFU, while motivational interviews and strengths-based techniques were used most often during reengagement visits. Outcomes like tracing activities efficacy, rates of reengagement and viral load reduction were reported as outcome measures. Conclusions: This review shows a recent and growing trend in developing and implementing patient reengagement strategies in HIV care. However, most of these strategies have been implemented in the United States and little information is available for other high-income countries. The procedures used to trace and contact LTFU are similar across reviewed studies, but their impact and sustainability are widely different depending on the country studied
Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification
- Author
- Aalfs Cora M.
- Agata Simona
- Aittomäki Kristiina
- Alducci Elisa
- Alonso Cerezo María Concepción
- Arnold Norbert
- Asperen Christi J.
- Auber Bernd
- Austin Rachel
- Azzollini Jacopo
- Balmaña Judith
- Barbieri Elena
- Bartram Claus R.
- Blanco Ana
- Blümcke Britta
- Bonache Sandra
- Bonanni Bernardo
- Borg Åke
- Bortesi Beatrice
- Brunet Joan
- Bruzzone Carla
- Bucksch Karolin
- Cagnoli Giulia
- Caldés Trinidad
- Caliebe Almuth
- Caligo Maria A.
- Calvello Mariarosaria
- Capone Gabriele L.
- Caputo Sandrine M.
- Carnevali Ileana
- Carrasco Estela
- Caux Moncoutier Virginie
- Cavalli Pietro
- Cini Giulia
- Clarke Edward M.
- Concolino Paola
- Cops Elisa J.
- Cortesi Laura
- Couch Fergus J.
- Darder Esther
- Dean Michael
- Debatin Irmgard
- Del Valle Jesús
- Delnatte Capucine
- Derive Nicolas
- Diez Orland
- Ditsch Nina
- Domchek Susan M.
- Dutrannoy Véronique
- Eccles Diana M.
- Ehrencrona Hans
- Enders Ute
- Engel Christoph
- Evans D. Gareth
- Farra Chantal
- Faust Ulrike
- Felbor Ute
- Feliubadaló i Elorza Maria Lídia
- Feroce Irene
- Fine Miriam
- Foulkes William D.
- Galvao Henrique C.R.
- Gambino Gaetana
- Garcia Encarna B.
- Gehrig Andrea
- Gensini Francesca
- Gerdes Anne Marie
- Germani Aldo
- Giesecke Jutta
- Gismondi Viviana
- Goldgar David E.
- González Sara
- Grau Garcés Èlia
- Grill Sabine
- Gross Eva
- Guerrieri Gonzaga Aliana
- Guillaud Bataille Marine
- Gutiérrez Enríquez Sara
- Gómez Carolina
- Haaf Thomas
- Hackmann Karl
- Hahnen Eric
- Hansen Thomas V.O.
- Harris Marion
- Hauke Jan
- Heinrich Tilman
- Hellebrand Heide
- Herold Karen N.
- Honisch Ellen
- Horvath Judit
- Houdayer Claude
- Hoya Miguel
- Hübbel Verena
- Iglesias Silvia
- Investigators Kconfab
- Izquierdo Angel
- James Paul A.
- Janssen Linda A.M.
- Jeschke Udo
- Kaulfuß Silke
- Keupp Katharina
- Kiechle Marion
- Krieger Sophie
- Kruse Torben A.
- Kvist Anders
- Kölbl Alexandra
- Lalloo Fiona
- Larsen Mirjam
- Lattimore Vanessa L.
- Lautrup Charlotte
- Ledig Susanne
- Leinert Elena
- Lewis Alexandra L.
- Li Hongyan
- Lim Joanna
- Loeffler Markus
- Lucci Cordisco Emanuela
- Lázaro García Conxi
- López Fernández Adrià
- Maass Nicolai
- Mackelenbergh Marion T.
- Manoukian Siranoush
- Marabelli Monica
- Matricardi Laura
- Meindl Alfons
- Michelli Rodrigo D.
- Moghadasi Setareh
- Moles Fernández Alejandro
- Montagna Marco
- Montalban Gemma
- Monteiro Alvaro N.
- Montes Eva
- Mori Luigi
- Moserle Lidia
- Mundhenke Christoph
- Müller Clemens R.
- Naldi Nadia
- Nathanson Katherine L.
- Navarro Matilde
- Nevanlinna Heli
- Nichols Cassandra B.
- Nicolo Arcangela
- Niederacher Dieter
- Nielsen Henriette R.
- Ong Kai Ren
- Pachter Nicholas
- Palmero Edenir I.
- Papi Laura
- Parsons Michael T.
- Pedersen Inge Søkilde
- Peissel Bernard
- Pfeifer Katharina
- Pineda Riu Marta
- Pohl Rescigno Esther
- Poplawski Nicola K.
- Porfirio Berardino
- Pérez Segura Pedro
- Quante Anne S.
- Radice Paolo
- Ramser Juliane
- Reis Rui M.
- Revillion Françoise
- Rhiem Kerstin
- Riboli Barbara
- Ritter Julia
- Rivera Daniela
- Rofes Paula
- Rump Andreas
- Salinas Monica
- Schmidt Gunnar
- Schmutzler Rita K.
- Schoenwiese Ulrike
- Seggewiß Jochen
- Solanes Ares
- Spurdle Amanda B.
- Steinemann Doris
- Stiller Mathias
- Stoppa Lyonnet Dominique
- Sullivan Kelly J.
- Susman Rachel
- Sutter Christian
- Sánchez de Abajo Ana María
- Tavtigian Sean V.
- Teo Soo H.
- Teulé Alex
- Thomassen Mads
- Tibiletti Maria Grazia
- Tischkowitz Marc
- Tognazzo Silvia
- Toland Amanda E.
- Tornero Eva
- Torres Esquius Sara
- Toss Angela
- Trainer Alison H.
- Tucker Katherine M.
- Tudini Emma
- Törngren Therese
- Varesco Liliana
- Vargas Parra Gardenia
- Varon Raymonda
- Vega Ana
- Velasco Àngela
- Vesper Anne Sophie
- Viel Alessandra
- Vreeswijk Maaike P. G.
- Wagner Sebastian A.
- Waha Anke
- Walker Logan C.
- Walters Rhiannon J.
- Wang Gohrke Shan
- Wappenschmidt Barbara
- Weber Bernhard H. F.
- Weichert Wilko
- Wieland Kerstin
- Wiesmüller Lisa
- Witzel Isabell
- Woodward Emma R.
- Wöckel Achim
- Zachariae Silke
- Zampiga Valentina
- Zeder Göß Christine
- Publication venue
- 'Wiley'
- Publication date
- 08/03/2021
- Field of study
The multifactorial likelihood analysis method has demonstrated utility for quantitative assessment of variant pathogenicity for multiple cancer syndrome genes. Independent data types currently incorporated in the model for assessing BRCA1 and BRCA2 variants include clinically calibrated prior probability of pathogenicity based on variant location and bioinformatic prediction of variant effect, co-segregation, family cancer history profile, co-occurrence with a pathogenic variant in the same gene, breast tumor pathology, and case-control information. Research and clinical data for multifactorial likelihood analysis were collated for 1,395 BRCA1/2 predominantly intronic and missense variants, enabling classification based on posterior probability of pathogenicity for 734 variants: 447 variants were classified as (likely) benign, and 94 as (likely) pathogenic; and 248 classifications were new or considerably altered relative to ClinVar submissions. Classifications were compared with information not yet included in the likelihood model, and evidence strengths aligned to those recommended for ACMG/AMP classification codes. Altered mRNA splicing or function relative to known nonpathogenic variant controls were moderately to strongly predictive of variant pathogenicity. Variant absence in population datasets provided supporting evidence for variant pathogenicity. These findings have direct relevance for BRCA1 and BRCA2 variant evaluation, and justify the need for gene-specific calibration of evidence types used for variant classification
TRY plant trait database – enhanced coverage and open access
- Author
- Aakala Tuomas
- Abedi Mehdi
- Acosta Alicia T. R.
- Adamidis George C.
- Adamson Kairi
- Aiba Masahiro
- Albert Cécile H.
- Alcántara Julio M.
- Alcázar C Carolina
- Aleixo Izabela
- Ali Hamada
- Amiaud Bernard
- Ammer Christian
- Amoroso Mariano M.
- Anand Madhur
- Anderson Carolyn
- Anten Niels
- Antos Joseph
- Apgaua Deborah Mattos Guimarães
- Ashman Tia‐Lynn
- Asmara Degi Harja
- Asner Gregory P.
- Aspinwall Michael
- Atkin Owen
- Aubin Isabelle
- Baastrup‐Spohr Lars
- Bahalkeh Khadijeh
- Bahn Michael
- Baker Timothy
- Baker William J.
- Bakker Jan P.
- Baldocchi Dennis
- Baltzer Jennifer
- Banerjee Arindam
- Baranger Anne
- Barlow Jos
- Barneche Diego R.
- Baruch Zdravko
- Bastianelli Denis
- Battles John
- Bauerle William
- Bauters Marijn
- Bazzato Erika
- Beckmann Michael
- Beeckman Hans
- Beer Arend Jacobus
- Beest Mariska
- Beierkuhnlein Carl
- Bekker Renee
- Belfry Gavin
- Belluau Michael
- Beloiu Mirela
- Benavides Raquel
- Benomar Lahcen
- Berdugo‐Lattke Mary Lee
- Berenguer Erika
- Bergamin Rodrigo
- Bergmann Carlucci Marcos
- Bergmann Joana
- Berner Logan
- Bernhardt‐Römermann Markus
- Bigler Christof
- Bjorkman Anne D.
- Blackman Chris
- Blanco Carolina
- Blonder Benjamin
- Blumenthal Dana
- Bocanegra‐González Kelly T.
- Bodegom Peter M.
- Boeckx Pascal
- Bohlman Stephanie
- Boisvert‐Marsh Laura
- Bond William
- Bond‐Lamberty Ben
- Boom Arnoud
- Boonman Coline C. F.
- Bordin Kauane
- Boughton Elizabeth H.
- Boukili Vanessa
- Bowman David M. J. S.
- Bravo Sandra
- Brendel Marco Richard
- Breugel Michiel
- Broadley Martin R.
- Brown Kerry A.
- Bruelheide Helge
- Brumnich Federico
- Bruun Hans Henrik
- Bruy David
- Buchanan Serra W.
- Bucher Solveig Franziska
- Buchmann Nina
- Buitenwerf Robert
- Bunker Daniel E.
- Burrascano Sabina
- Burslem David F. R. P.
- Butterfield Bradley J.
- Byun Chaeho
- Böhning‐Gaese Katrin
- Bönisch Gerhard
- Bürger Jana
- Caccianiga Marco
- Cadotte Marc
- Cailleret Maxime
- Camac James
- Camarero Jesús Julio
- Campany Courtney
- Campetella Giandiego
- Campos Juan Antonio
- Cano‐Arboleda Laura
- Canullo Roberto
- Carbognani Michele
- Carvalho Fabio
- Casanoves Fernando
- Castagneyrol Bastien
- Catford Jane A.
- Cavender‐Bares Jeannine
- Cerabolini Bruno E. L.
- Cervellini Marco
- Chacón‐Madrigal Eduardo
- Chapin F. Stuart
- Chapin Kenneth
- Chelli Stefano
- Chen Anping
- Chen Si‐Chong
- Cherubini Paolo
- Chianucci Francesco
- Choat Brendan
- Chung Kyong‐Sook
- Chytrý Milan
- Ciccarelli Daniela
- Coll Lluís
- Collins Courtney G.
- Conti Luisa
- Coomes David
- Cornelissen Johannes H. C.
- Cornwell William K.
- Corona Piermaria
- Coyea Marie
- Craine Joseph
- Craven Dylan
- Cromsigt Joris P. G. M.
- Csecserits Anikó
- Cufar Katarina
- Cuntz Matthias
- Dahlin Kyla M.
- Dainese Matteo
- Dalke Igor
- Dalle Fratte Michele
- Dang‐Le Anh Tuan
- Danihelka Jirí
- Dannoura Masako
- Dawson Samantha
- De Frutos Angel
- De Long Jonathan R.
- Dechant Benjamin
- Delagrange Sylvain
- Delpierre Nicolas
- Derroire Géraldine
- Dias Arildo S.
- Diaz‐Toribio Milton Hugo
- Dimitrakopoulos Panayiotis G.
- Dios Victor Resco
- Dobrowolski Mark
- Doktor Daniel
- Domingues Tomas F.
- Dong Ning
- Dransfield John
- Dressler Stefan
- Duarte Leandro
- Ducouret Emilie
- Dullinger Stefan
- Durka Walter
- Duursma Remko
- Dymova Olga
- Díaz Sandra
- Dřevojan Pavel
- Eckstein Rolf Lutz
- Ejtehadi Hamid
- Elser James
- Emilio Thaise
- Engemann Kristine
- Erfanian Mohammad Bagher
- Erfmeier Alexandra
- Esquivel‐Muelbert Adriane
- Esser Gerd
- Estiarte Marc
- E‐Vojtkó Anna
- Fagan William F.
- Fagúndez Jaime
- Falster Daniel S.
- Fan Ying
- Fang Jingyun
- Farris Emmanuele
- Fazlioglu Fatih
- Feng Yanhao
- Fernandez‐Mendez Fernando
- Ferrara Carlotta
- Ferreira Joice
- Fidelis Alessandra
- Finegan Bryan
- Firn Jennifer
- Flowers Timothy J.
- Flynn Dan F. B.
- Fontana Veronika
- Forey Estelle
- Forgiarini Cristiane
- Frangipani Marcelo
- Frank Dorothea
- François Louis
- Frenette‐Dussault Cedric
- Freschet Grégoire T.
- Fry Ellen L.
- Fyllas Nikolaos M.
- Gachet Sophie
- Gallagher Rachael
- Ganade Gislene
- Ganga Francesca
- García‐Palacios Pablo
- Gargaglione Verónica
- Garnier Eric
- Garrido Jose Luis
- Gasper André Luís
- Gea‐Izquierdo Guillermo
- Gibson David
- Gillison Andrew N.
- Giroldo Aelton
- Glasenhardt Mary‐Claire
- Gleason Sean
- Gliesch Mariana
- Goldberg Emma
- Gonzalez‐Akre Erika
- Gonzalez‐Andujar Jose L.
- González‐Melo Andrés
- González‐Robles Ana
- Graae Bente Jessen
- Granda Elena
- Graves Sarah
- Green Walton A.
- Gregor Thomas
- Gross Nicolas
- Guerin Greg R.
- Gutiérrez Alvaro G.
- Göldel Bastian
- Günther Angela
- Haddock Lillie
- Haines Anna
- Hall Jefferson
- Hambuckers Alain
- Han Wenxuan
- Harrison Sandy P.
- Hattingh Wesley
- Hawes Joseph E.
- He Pengcheng
- He Tianhua
- Heberling Jacob Mason
- Helm Aveliina
- Hempel Stefan
- Hentschel Jörn
- Hereş Ana‐Maria
- Herz Katharina
- Heuertz Myriam
- Hickler Thomas
- Hietz Peter
- Higuchi Pedro
- Hipp Andrew L.
- Hirons Andrew
- Hock Maria
- Hogan James Aaron
- Holl Karen
- Honnay Olivier
- Hornstein Daniel
- Hou Enqing
- Hough‐Snee Nate
- Hovstad Knut Anders
- Hérault Bruno
- Ichie Tomoaki
- Igić Boris
- Illa Estela
- Isaac Marney
- Ishihara Masae
- Ivanov Leonid
- Ivanova Larissa
- Iversen Colleen M.
- Izquierdo Jordi
- Jackson Benjamin
- Jackson Robert B.
- Jactel Hervé
- Jagodzinski Andrzej M.
- Jandt Ute
- Jansen Steven
- Jenkins Thomas
- Jentsch Anke
- Jespersen Jens Rasmus Plantener
- Jiang Guo‐Feng
- Johansen Jesper Liengaard
- Johnson David
- Jokela Eric J.
- Joly Carlos Alfredo
- Jordan Gregory J.
- Joseph Grant Stuart
- Junaedi Decky
- Junker Robert R.
- Justes Eric
- Kabzems Richard
- Kane Jeffrey
- Kaplan Zdenek
- Kattenborn Teja
- Kattge Jens
- Kavelenova Lyudmila
- Kearsley Elizabeth
- Kempel Anne
- Kenzo Tanaka
- Kerkhoff Andrew
- Khalil Mohammed I.
- Kinlock Nicole L.
- Kissling Wilm Daniel
- Kitajima Kaoru
- Kitzberger Thomas
- Kjøller Rasmus
- Klein Tamir
- Kleunen Mark
- Kleyer Michael
- Klimešová Jitka
- Klipel Joice
- Kloeppel Brian
- Klotz Stefan
- Knops Johannes M. H.
- Kohyama Takashi
- Koike Fumito
- Kollmann Johannes
- Komac Benjamin
- Komatsu Kimberly
- Kraft Nathan J. B.
- Kramer Koen
- Kreft Holger
- Kumarathunge Dushan
- Kuppler Jonas
- Kurokawa Hiroko
- Kurosawa Yoko
- Kuyah Shem
- König Christian
- Kühn Ingolf
- Laclau Jean‐Paul
- Lafleur Benoit
- Lallai Erik
- Lamb Eric
- Lamprecht Andrea
- Larkin Daniel J.
- Laughlin Daniel
- Lavorel Sandra
- Le Bagousse‐Pinguet Yoann
- Leadley Paul
- Lee Tali
- Lens Frederic
- Lewis Simon L.
- Lhotsky Barbara
- Li Xine
- Li Yuanzhi
- Lichstein Jeremy W.
- Liebergesell Mario
- Lim Jun Ying
- Lin Yan‐Shih
- Linares Juan Carlos
- Liu Chunjiang
- Liu Daijun
- Liu Udayangani
- Livingstone Stuart
- Llusià Joan
- Lohbeck Madelon
- Lopez‐Gonzalez Gabriela
- Lososová Zdeňka
- Louault Frédérique
- Lukeš Petr
- Lukács Balázs A.
- Luo Yunjian
- Lussu Michele
- López‐García Álvaro
- Ma Siyan
- Maciel Rabelo Pereira Camilla
- Mack Michelle
- Maire Guerric
- Maire Vincent
- Malhado Ana Claudia Mendes
- Mallik Azim
- Manning Peter
- Manzoni Stefano
- Marchetti Zuleica
- Marchino Luca
- Marcilio‐Silva Vinicius
- Marcon Eric
- Marignani Michela
- Markesteijn Lars
- Marques Marcia
- Martin Adam
- Martínez‐Garza Cristina
- Martínez‐Vilalta Jordi
- Mason Kelly
- Mason Norman
- Massad Tara Joy
- Masse Jacynthe
- Mayrose Itay
- Mazzochini Guilherme G.
- Mašková Tereza
- McCarthy James
- McCormack M. Luke
- McCulloh Katherine
- McFadden Ian R.
- McGill Brian J.
- McPartland Mara Y.
- Medeiros Juliana S.
- Medlyn Belinda
- Meerts Pierre
- Mehrabi Zia
- Meir Patrick
- Melo Felipe P. L.
- Mencuccini Maurizio
- Meredieu Céline
- Merwe Stephni
- Messier Julie
- Metsaranta Juha
- Michaletz Sean T.
- Michelaki Chrysanthi
- Migalina Svetlana
- Milla Ruben
- Miller Jesse E. D.
- Minden Vanessa
- Ming Ray
- Mokany Karel
- Moles Angela T.
- Molnár Attila, V
- Molofsky Jane
- Molz Martin
- Montgomery Rebecca A.
- Monty Arnaud
- Moravcová Lenka
- Moreno‐Martínez Alvaro
- Moretti Marco
- Mori Akira S.
- Mori Shigeta
- Morris Dave
- Morrison Jane
- Mucina Ladislav
- Mueller Sandra
- Muir Christopher D.
- Munoz François
- Myers‐Smith Isla H.
- Myster Randall W.
- Mäkelä Annikki
- Mäkinen Harri
- Mészáros Ilona
- Müller Sandra Cristina
- Nagano Masahiro
- Naidu Shawna
- Narayanan Ayyappan
- Natesan Balachandran
- Negoita Luka
- Nelson Andrew S.
- Neuschulz Eike Lena
- Ni Jian
- Niedrist Georg
- Nieto Jhon
- Niinemets Ülo
- Nolan Rachael
- Nottebrock Henning
- Nouvellon Yann
- Novakovskiy Alexander
- Nystuen Kristin Odden
- O\u27Grady Anthony
- O\u27Hara Kevin
- O\u27Reilly‐Nugent Andrew
- Oakley Simon
- Oberhuber Walter
- Ohtsuka Toshiyuki
- Oliveira Ricardo
- Olson Mark E.
- Onipchenko Vladimir
- Onoda Yusuke
- Onstein Renske E.
- Ordonez Jenny C.
- Osada Noriyuki
- Ostonen Ivika
- Ottaviani Gianluigi
- Otto Sarah
- Overbeck Gerhard E.
- Ozinga Wim A.
- Pahl Anna T.
- Paine C. E. Timothy
- Pakeman Robin J.
- Papageorgiou Aristotelis C.
- Parfionova Evgeniya
- Patacca Marco
- Paula Susana
- Paule Juraj
- Pauli Harald
- Pausas Juli G.
- Peco Begoña
- Penuelas Josep
- Perea Antonio
- Peri Pablo Luis
- Petisco‐Souza Ana Carolina
- Petraglia Alessandro
- Petritan Any Mary
- Phillips Oliver L.
- Pierce Simon
- Pillar Valério D.
- Pinho Bruno X.
- Pisek Jan
- Plas Fons
- Pomogaybin Alexandr
- Poorter Hendrik
- Portsmuth Angelika
- Poschlod Peter
- Potvin Catherine
- Pounds Devon
- Powell A. Shafer
- Power Sally A.
- Prentice Iain Colin
- Prinzing Andreas
- Puglielli Giacomo
- Pyšek Petr
- Pärtel Meelis
- Raevel Valerie
- Rammig Anja
- Ransijn Johannes
- Ray Courtenay A.
- Reich Peter B.
- Reichstein Markus
- Reid Douglas E. B.
- Ribeiro Sabina
- Richardson Sarah
- Riibak Kersti
- Rillig Matthias C.
- Riviera Fiamma
- Robert Elisabeth M. R.
- Roberts Scott
- Robroek Bjorn
- Roddy Adam
- Rodrigues Arthur Vinicius
- Rogers Alistair
- Rollinson Emily
- Rolo Victor
- Ronzhina Dina
- Roscher Christiane
- Rosell Julieta A.
- Rosenfield Milena Fermina
- Rossi Christian
- Roux Elizabeth
- Roux Peter C.
- Roy David B.
- Royer‐Tardif Samuel
- Ruiz‐Peinado Ricardo
- Rumpf Sabine B.
- Rusch Graciela M.
- Ryo Masahiro
- Réjou‐Méchain Maxime
- Römermann Christine
- Rüger Nadja
- Sack Lawren
- Saldaña Angela
- Salgado‐Negret Beatriz
- Salguero‐Gomez Roberto
- Sande Masha T.
- Santacruz‐García Ana Carolina
- Santa‐Regina Ignacio
- Santos Joaquim
- Sardans Jordi
- Scalon Marina C.
- Schamp Brandon
- Scherer‐Lorenzen Michael
- Schleuning Matthias
- Schmid Bernhard
- Schmidt Marco
- Schmitt Sylvain
- Schneider Julio V.
- Schowanek Simon D.
- Schrader Julian
- Schrodt Franziska
- Schuldt Bernhard
- Schurr Frank
- Selaya Garvizu Galia
- Semchenko Marina
- Seymour Colleen
- Sfair Julia C.
- Sharpe Joanne M.
- Sheppard Christine S.
- Sheremetiev Serge
- Shiodera Satomi
- Shipley Bill
- Shovon Tanvir Ahmed
- Siebenkäs Alrun
- Sierra Carlos
- Silva Ana Carolina
- Silva Mateus
- Silva Vasco
- Sitzia Tommaso
- Sjöman Henrik
- Slot Martijn
- Smith Nicholas G.
- Sodhi Darwin
- Soltis Douglas
- Soltis Pamela
- Somers Ben
- Sonnier Grégory
- Sosinski Enio Egon, Jr
- Soudzilovskaia Nadejda A.
- Souza Alexandre F.
- Spasojevic Marko
- Sperandii Marta Gaia
- Stan Amanda B.
- Stegen James
- Steinbauer Klaus
- Stephan Jörg G.
- Sterck Frank
- Stojanovic Dejan B.
- Strydom Tanya
- Suarez Maria Laura
- Svenning Jens‐Christian
- Svitková Ivana
- Svitok Marek
- Svoboda Miroslav
- Swaine Emily
- Swenson Nathan
- Sørensen Mia Vedel
- Tabarelli Marcelo
- Takagi Kentaro
- Tappeiner Ulrike
- Tarifa Rubén
- Tarin Tonantzin
- Tautenhahn Susanne
- Tauugourdeau Simon
- Tavsanoglu Cagatay
- Tedersoo Leho
- Thiffault Nelson
- Thom Dominik
- Thomas Evert
- Thompson Ken
- Thornton Peter E.
- Thuiller Wilfried
- Tichý Lubomír
- Tissue David
- Tjoelker Mark G.
- Tng David Yue Phin
- Tobias Joseph
- Torres‐Ruiz José M.
- Treurnicht Martina
- Trivellone Valeria
- Trolliet Franck
- Trotsiuk Volodymyr
- Tsakalos James L.
- Tsiripidis Ioannis
- Tysklind Niklas
- Tóthmérész Béla
- Török Péter
- Umehara Toru
- Usoltsev Vladimir
- Vadeboncoeur Matthew
- Vaezi Jamil
- Valladares Fernando
- Vamosi Jana
- Van Cleemput Elisa
- Van Meerbeek Koenraad
- Vanderwel Mark
- Vanselow Kim André
- Varone Laura
- Vasquez Valderrama Maribel Yesenia
- Vassilev Kiril
- Vellend Mark
- Veneklaas Erik J.
- Verbeeck Hans
- Verheyen Kris
- Vibrans Alexander
- Vieira Ima
- Villacís Jaime
- Violle Cyrille
- Vivek Pandi
- Vårhammar Angelica
- Wagner Katrin
- Waldram Matthew
- Waldron Anthony
- Walker Anthony P.
- Waller Martyn
- Walther Gabriel
- Wang Feng
- Wang Han
- Wang Weiqi
- Watkins Harry
- Watkins James
- Weber Ulrich
- Weedon James T.
- Weg Martine
- Wei Liping
- Weigelt Patrick
- Weiher Evan
- Wells Aidan W.
- Wellstein Camilla
- Wenk Elizabeth
- Werner Gijsbert D. A.
- Westoby Mark
- Westwood Alana
- White Philip John
- Whitten Mark
- Williams Mathew
- Winkler Daniel E.
- Winter Klaus
- Wirth Christian
- Womack Chevonne
- Wright Ian J.
- Wright Justin
- Wright S. Joseph
- Ximenes Fabiano
- Yamada Toshihiro
- Yamaji Keiko
- Yanai Ruth
- Yankov Nikolay
- Yguel Benjamin
- Zanini Kátia Janaina
- Zanne Amy E.
- Zelený David
- Zhao Yun‐Peng
- Zheng Ji
- Zheng Jingming
- Ziemińska Kasia
- Zirbel Chad R.
- Zizka Georg
- Zotz Gerhard
- Zo‐Bi Irié Casimir
- Öllerer Kinga
- Publication venue
- John Wiley and Sons
- Publication date
- 10/01/2020
- Field of study
Plant traits - the morphological, anatomical, physiological, biochemical and phenological characteristics of plants - determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits - almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives
Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV
- Author
- Aarrestad Thea Klaeboe
- Aarup Petersen Henriette
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdullin Salavat
- Abercrombie Daniel
- Abreu A.
- Acharya Himal
- Acosta Darin
- Adam Wolfgang
- Adamidis K.
- Adams Eric
- Adams Mark Raymond
- Adams Todd
- Addesa Francesca Maria
- Adloff Catherine
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmed Asar
- Ahuja Sudha
- Aime` Chiara
- Aime‘ C.
- Akchurin Nural
- Akgun Bora
- Akpinar Alp
- Albergo Sebastiano
- Albert Andreas
- Albrecht Steffen
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Alison John
- Almond John
- Alpana Km
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gallo Pereira Miguel
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrozas Marijus
- Amendola Chiara
- Amin Nick
- Amram Oz
- Amsler Claude
- An Sitong
- An Ying
- Anagnostou Georgios
- Andrea Jeremy
- Andreassi Guido
- Andreev Vladimir
- Andreev Yu.
- Andreev Yuri
- Andrejkovic Janik Walter
- Andrews Michael Benjamin
- Androsov Konstantin
- Anguiano J.
- Antchev Georgy
- Anthony David
- Antunovic Zeljko
- Apollinari Giorgio
- Apparu Dylan
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Aruta Caterina
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Asghar Muhammad Irfan
- Asilar Ece
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awais Ali
- Awan Muhammad Imran Malik
- Ayala Edy
- Ayala Gabriel
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M
- Babaev Anton
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden A.
- Baden Drew
- Baechler Joachim
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Bakshi Amandeep Singh
- Baldenegro Barrera Cristian
- Ban Yong
- Band Reyer
- Bandyopadhyay Hirak
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barnes Virgil E
- Barney David
- Baron Owen
- Barria Patrizia
- Barrio Luna Mar
- Barroso Ferreira Filho Mapse
- Bartek Rachel
- Bartosik Nazar
- Bartók Márton
- Bastos Diogo
- Battilana Carlo
- Baty Austin
- Bauer Gerry
- Bauerdick Lothar AT
- Baxter Samuel
- Bayatmakou M.
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Becerril Gonzalez Hugo
- Bechtel Janek
- Beghin Diego
- Behera Prafulla Kumar
- Behera Subash Chandra
- Behnke Olaf
- Bein Samuel
- Belforte Stefano
- Bell Ken W
- Bellan Riccardo
- Belloni Alberto
- Bellora Andrea
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benecke Anna
- Benelli Gabriele
- Benitez Jose F
- Benussi Luigi
- Berenguer Antequera Jorge
- Bergauer Thomas
- Berger Pirmin
- Beri Suman Bala
- Bermúdez Martínez Armando
- Bernardes Cesar Augusto
- Bernet Colin
- Berry Douglas
- Berryhill Jeffrey
- Bertacchi Valerio
- Besancon Marc
- Bestintzanos I.
- Bethani Agni
- Beyrouthy Taha
- Bhal Eshwen
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- Wilson Graham
- Wilson Jonathan
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- Winer Brian L
- Winterbottom Daniel
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- Wissing Christoph
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- Xiang Yifan
- Xiao Jie
- Xiao Meng
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- Yagil Avraham
- Yalvac Metin
- Yan Furong
- Yan Xuli
- Yang S.
- Yang Shuai
- Yang Unki
- Yang Yu Chul
- Yao Yao
- Yarar Hevjin
- Yates Brent
- Yazgan Efe
- Ye Zhenyu
- Yetkin Elif Asli
- Yi Kai
- Yigitbasi Efe
- Yohay Rachel
- Yoo Hwi Dong
- Yoo Jaehyeok
- Yoon Inseok
- You Zhengyun
- Yu David
- Yu Geum Bong
- Yu Intae
- Yu Pei-rong
- Yu Shin-Shan
- Yuan Li
- Yuan Siqi
- Yuldashev Bekhzod S
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabi Alexandre
- Zacharopoulou Anna
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zeinali Maryam
- Zeuner Wolfram Dietrich
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Liuyao
- Zhang Wenyu
- Zhang Yi
- Zhang Yousen
- Zhang Zhicai
- Zhao Jingzhou
- Zhizhin Ilia
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Ziemons Tim
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zotz Alexander
- Zou David
- Zou Rui
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Zygala Lara
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- Publication date
- 01/01/2021
- Field of study
A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe
Probing effective field theory operators in the associated production of top quarks with a Z boson in multilepton final states at root s=13 TeV
- Author
- Aarrestad Thea Klaeboe
- Aarup Petersen Henriette
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdalla Hassan
- Abdullin Salavat
- Abercrombie Daniel
- Abreu A.
- Acharya Himal
- Acosta Darin
- Adam Wolfgang
- Adamidis K.
- Adamov George
- Adams Eric
- Adams Mark Raymond
- Adams Todd
- Addesa Francesca Maria
- Adloff Catherine
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmed Asar
- Ahuja Sudha
- Aime` Chiara
- Aime‘ C.
- Akchurin Nural
- Akgun Bora
- Akpinar Alp
- Albergo Sebastiano
- Albert Andreas
- Albrecht Steffen
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Alison John
- Almond John
- Alpana Km
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gallo Pereira Miguel
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrozas Marijus
- Amendola Chiara
- Amin Nick
- Amram Oz
- Amsler Claude
- An Sitong
- An Ying
- Anagnostou Georgios
- Andrea Jeremy
- Andreassi Guido
- Andreev Vladimir
- Andreev Yu.
- Andreev Yuri
- Andrejkovic Janik Walter
- Andrews Michael Benjamin
- Androsov Konstantin
- Anguiano J.
- Antchev Georgy
- Anthony David
- Antunovic Zeljko
- Apollinari Giorgio
- Apparu Dylan
- Appelt Eric
- Apresyan Artur
- Apyan Aram
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- Argiro Stefano
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- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Asghar Muhammad Irfan
- Asilar Ece
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- Atakisi Ismail Okan
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- Hollar Jonathan
- Holmberg Mei-li
- Hong Byung-Sik
- Hoorani Hafeez R
- Horisberger Roland
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- Norberg Scarlet
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- Scham M.
- Scheurer Valerie
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- Yuldashev Bekhzod S
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- Yusli Mohd Nizam
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- Zacharopoulou Anna
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zeinali Maryam
- Zeuner Wolfram Dietrich
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Liuyao
- Zhang Wenyu
- Zhang Yi
- Zhang Yousen
- Zhang Zhicai
- Zhao Jingzhou
- Zhizhin Ilia
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Ziemons Tim
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zotz Alexander
- Zou David
- Zou Rui
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Zygala Lara
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Peer reviewe
Combined searches for the production of supersymmetric top quark partners in proton-proton collisions at root s=13 TeV
- Author
- Aarrestad Thea Klaeboe
- Aarup Petersen Henriette
- Abbaneo Duccio
- Abbiendi Giovanni
- Abbrescia Marcello
- Abdalla Hassan
- Abdullin Salavat
- Abercrombie Daniel
- Abreu A.
- Acharya Himal
- Acosta Darin
- Adam Wolfgang
- Adamov George
- Adams Eric
- Adams Mark Raymond
- Adams Todd
- Addesa Francesca Maria
- Adloff Catherine
- Adzic Petar
- Afanasiev Serguei
- Agapitos Antonis
- Agarwal Garvita
- Aggleton Robin
- Agram Jean-Laurent
- Aguilar-Benitez Manuel
- Ahmad Ashfaq
- Ahmad Muhammad
- Ahmed Asar
- Ahuja Sudha
- Aime` Chiara
- Aime‘ C.
- Akchurin Nural
- Akgun Bora
- Akpinar Alp
- Albergo Sebastiano
- Albert Andreas
- Albrecht Steffen
- Albrow Michael
- Alcaraz Maestre Juan
- Aldaya Martin Maria
- Aldá Júnior Walter Luiz
- Aleksandrov Aleksandar
- Alexander James
- Alhusseini Mohammad
- Alimena Juliette
- Alison John
- Almond John
- Alpana Km
- Alvarez Gonzalez Barbara
- Alverson George
- Alves Gallo Pereira Miguel
- Alves Gilvan
- Aly Reham
- Alyari Maral
- Amapane Nicola
- Ambrozas Marijus
- Amendola Chiara
- Amin Nick
- Amram Oz
- Amsler Claude
- An Sitong
- An Ying
- Anagnostou Georgios
- Andrea Jeremy
- Andreassi Guido
- Andreev Vladimir
- Andreev Yu.
- Andreev Yuri
- Andrejkovic Janik Walter
- Andrews Michael Benjamin
- Androsov Konstantin
- Anguiano J.
- Antchev Georgy
- Anthony David
- Antunovic Zeljko
- Apollinari Giorgio
- Apparu Dylan
- Appelt Eric
- Apresyan Artur
- Apyan Aram
- Araujo Mariana
- Arcaro Daniel
- Arcidiacono Roberta
- Arenton Michael Wayne
- Argiro Stefano
- Arneodo Michele
- Aruta Caterina
- Asavapibhop Burin
- Asawatangtrakuldee Chayanit
- Asenov Patrick
- Asghar Muhammad Irfan
- Asilar Ece
- Askew Andrew
- Asmuss Paul
- Atakisi Ismail Okan
- Attikis Alexandros
- Auffray Etiennette
- Aushev Tagir
- Auzinger Georg
- Avati Valentina
- Avery Paul
- Avila Carlos
- Awais Ali
- Awan Muhammad Imran Malik
- Ayala Edy
- Ayala Gabriel
- Azarkin Maksim
- Azhgirey Igor
- Aziz Tariq
- Azzi Patrizia
- Azzurri Paolo
- Baarmand Marc M.
- Babaev Anton
- Babounikau Illia
- Bacchetta Nicola
- Bachiller Irene
- Bachtis Michail
- Backhaus Malte
- Baden A.
- Baden Drew
- Baechler Joachim
- Bagliesi Giuseppe
- Bahinipati Seema
- Baillon Paul
- Bainbridge Robert
- Bakas Georgios
- Bakhshiansohi Hamed
- Bakshi Amandeep Singh
- Baldenegro Barrera Cristian
- Ban Yong
- Band Reyer
- Bandyopadhyay Hirak
- Banerjee Sudeshna
- Banerjee Sunanda
- Bansal Sunil
- Barbagli Giuseppe
- Barberis Emanuela
- Bargassa Pedrame
- Baringer Philip
- Barnes Virgil E.
- Barney David
- Baron Owen
- Barrio Luna Mar
- Barroso Ferreira Filho Mapse
- Bartek Rachel
- Bartosik Nazar
- Bartók Márton
- Bastos Diogo
- Battilana Carlo
- Baty Austin
- Bauer Gerry
- Bauerdick Lothar A. T.
- Baxter Samuel
- Bayshev Igor
- Bean Alice
- Beauceron Stephanie
- Beaudette Florian
- Becerril Gonzalez Hugo
- Bechtel Janek
- Beghin Diego
- Behera Prafulla Kumar
- Behera Subash Chandra
- Behnke Olaf
- Bein Samuel
- Belforte Stefano
- Bell Ken W.
- Bellan Riccardo
- Belloni Alberto
- Bellora Andrea
- Belyaev Alexander
- Belyaev Andrey
- Benaglia Andrea
- Benato Lisa
- Bencze Gyorgy
- Bendavid Joshua
- Benecke Anna
- Benelli Gabriele
- Benitez Jose F.
- Benussi Luigi
- Berenguer Antequera Jorge
- Bergauer Thomas
- Berger Pirmin
- Berger Thomas
- Beri Suman Bala
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- Beyrouthy Taha
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- Bhowmik Sandeep
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- Bi Ran
- Bialkowska Helena
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- Bianco Michele
- Bianco Stefano
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- Bilin Bugra
- Bin Anuar Afiq Aizuddin
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- Bisello Dario
- Black Kevin
- Blekman Freya
- Blinov Vladimir
- Bloch Daniel
- Bloch Philippe
- Bloom Kenneth
- Bluj Michal
- Blumenfeld Barry
- Boccali Tommaso
- Bocci Andrea
- Bodek Arie
- Boimska Bozena
- Boletti Alessio
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- Bornheim Adolf
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- Borshch Vladislav
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- Bossini Edoardo
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- Botta Valeria
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- Bozzo Marco
- Bragagnolo Alberto
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- Brainerd Christopher
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- Brandt Stephanie
- Branson James G.
- Breedon Richard
- Breeze Shane
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- Chatterjee Suman
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- Cox Peter Timothy
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- Cummings Grace
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- D'Alfonso Mariarosaria
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- Das Abhishek
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- de Barbaro Pawel
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- De Iorio Agostino
- De Jesus Damiao Dilson
- De La Cruz Begona
- De La Cruz-Burelo Eduard
- De Lentdecker Gilles
- De Leo Ksenia
- De Moraes Gregores Eduardo
- De Palma Mauro
- De Roeck Albert
- De Souza Lemos Dener
- de Trocóniz Jorge F.
- De Wit Adinda
- De Wolf Eddi A.
- Decaro Matthew
- Deelen Nikkie
- Defranchis Matteo Maria
- Deile Mario
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- Delcourt Martin
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- Xiang Yifan
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- Xiao Rui
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- Yang Shuai
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- Yarar Hevjin
- Yates Brent
- Yazgan Efe
- Ye Zhenyu
- Yetkin Elif Asli
- Yi Kai
- Yigitbasi Efe
- Yohay Rachel
- Yoo Hwi Dong
- Yoo Jaehyeok
- Yoon Inseok
- You Zhengyun
- Yu David
- Yu Geum Bong
- Yu Intae
- Yu Pei-rong
- Yu Shin-Shan
- Yuan Li
- Yuan Siqi
- Yuldashev Bekhzod S.
- Yumiceva Francisco
- Yusli Mohd Nizam
- Zabi Alexandre
- Zacharopoulou Anna
- Zahid Sema
- Zaleski Shawn
- Zalewski Piotr
- Zanetti Marco
- Zarubin Anatoli
- Zarucki Mateusz
- Zecchinelli Angelo Giacomo
- Zeinali Maryam
- Zeuner Wolfram Dietrich
- Zghiche Amina
- Zhang Fengwangdong
- Zhang Huaqiao
- Zhang Jingyu
- Zhang Liuyao
- Zhang Sijing
- Zhang Wenyu
- Zhang Yi
- Zhang Yousen
- Zhang Zhicai
- Zhao Jingzhou
- Zhizhin Ilia
- Zhokin Alexander
- Zhu De Hua
- Zhu Ren-Yuan
- Ziemons Tim Matthias
- Zoi Irene
- Zolkapli Zukhaimira
- Zorbakir Ibrahim Soner
- Zorbilmez Caglar
- Zotto Pierluigi
- Zou David
- Zou Rui
- Zucchetta Alberto
- Zumerle Gianni
- Zuo Xunwu
- Zuolo Davide
- Zygala Lara
- Álvarez Fernández Adrian
- Özçelik Özlem
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
A combination of searches for top squark pair production using proton-proton collision data at a center-of-mass energy of 13 TeV at the CERN LHC, corresponding to an integrated luminosity of 137 fb(-1) collected by the CMS experiment, is presented. Signatures with at least 2 jets and large missing transverse momentum are categorized into events with 0, 1, or 2 leptons. New results for regions of parameter space where the kinematical properties of top squark pair production and top quark pair production are very similar are presented. Depending on themodel, the combined result excludes a top squarkmass up to 1325 GeV for amassless neutralino, and a neutralinomass up to 700 GeV for a top squarkmass of 1150 GeV. Top squarks with masses from 145 to 295 GeV, for neutralino masses from 0 to 100 GeV, with a mass difference between the top squark and the neutralino in a window of 30 GeV around the mass of the top quark, are excluded for the first time with CMS data. The results of theses searches are also interpreted in an alternative signal model of dark matter production via a spin-0 mediator in association with a top quark pair. Upper limits are set on the cross section for mediator particle masses of up to 420 GeV
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