8 research outputs found
Temporal bone verrucous carcinoma: outcomes and treatment controversy
- Author
- A Ferlito
- A Ferlito
- AF Jahn
- Akira Ishiyama
- B O’Sullivan
- BB Koch
- DJ Chute
- DR Edelstein
- DW Proops
- EA Fonts
- FT Kraus
- G Cristalli
- GE Woodson
- GR Kletzker
- Guy F. Juillard
- H Hagiwara
- H Kunst
- J Yiotakis
- JA Lundgren
- JA Minielly
- JE Bouquot
- JE Medina
- JG Batsakis
- JJ Pindborg
- JM McCoy
- JM McCoy
- JM Pleat
- JS McDonald
- JV Diengdoh
- LB Aydogan
- LD Thompson
- LJ Orvidas
- M Maurizi
- ME Tharp 2nd
- Mia E. Miller
- ML Farrell
- Neil Martin
- P Hagen
- P Strojan
- R Rajendran
- RR Walvekar
- S Edstrom
- SF Pattee
- SH Huang
- Sunita Bhuta
- TV McCaffrey
- WD Rider
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2010
- Field of study
Verrucous carcinoma is a rare tumor that presents in the head and neck with the most common sites being the oral cavity and larynx. Fourteen cases of verrucous carcinoma of the temporal bone have been described in literature; this study aims to examine treatment outcomes and discuss the controversy surrounding postoperative radiation. The study design included a literature review along with individual case report in the setting of a tertiary care medical center. Outcome analysis of all cases of verrucous carcinoma of the temporal bone, which are documented in the English literature, and presentation of a single patient report including gross, histologic and radiologic analyses were performed. The longest recorded survival for verrucous carcinoma of the temporal bone occurs in patients treated with surgery alone. Poorer outcomes for patients treated with adjuvant (chemo)radiation may be due to more advanced stage of disease at the time of treatment. Early reports of radiation leading to tumor dedifferentiation or early recurrence are not supported by more recent studies. Whether adjuvant radiation therapy is indicated in verrucous carcinoma of the temporal bone remains controversial
Mutant Versions of the S. cerevisiae Transcription Elongation Factor Spt16 Define Regions of Spt16 That Functionally Interact with Histone H3
- Author
- A Jamai
- A Lloyd
- A Rowley
- AA Duina
- AA Duina
- AF O'Donnell
- AF O'Donnell
- Andrea A. Duina
- AP VanDemark
- AP VanDemark
- AR Rhoades
- B Li
- Catherine N. Myers
- CD Kaplan
- D Kolodrubetz
- D Reinberg
- DM Keller
- DR Evans
- EA Malone
- F Winston
- F Winston
- G Orphanides
- Gary B. Berner
- GP Pfeifer
- H Ferreira
- H Xin
- J Wittmeyer
- JA Martens
- Jennifer A. Harper
- Joseph H. Holthoff
- K Luger
- K Luger
- Kirby Martinez-Fonts
- L Bai
- LA Selth
- Laura N. Rusche
- M Hampsey
- MD Rose
- Megan N. Taylor
- MJ Carrozza
- NK Brewster
- NK Brewster
- P Andre
- PB Mason
- R Belotserkovskaya
- S Ruone
- Sarah Alford
- T Formosa
- T Formosa
- T Formosa
- T Stuwe
- V Cheung
- XC Li-Sucholeiki
- YJ Park
- Publication venue
- Public Library of Science
- Publication date
- Field of study
In eukaryotic cells, the highly conserved FACT (FAcilitates Chromatin Transcription) complex plays important roles in several chromatin-based processes including transcription initiation and elongation. During transcription elongation, the FACT complex interacts directly with nucleosomes to facilitate histone removal upon RNA polymerase II (Pol II) passage and assists in the reconstitution of nucleosomes following Pol II passage. Although the contribution of the FACT complex to the process of transcription elongation has been well established, the mechanisms that govern interactions between FACT and chromatin still remain to be fully elucidated. Using the budding yeast Saccharomyces cerevisiae as a model system, we provide evidence that the middle domain of the FACT subunit Spt16 – the Spt16-M domain – is involved in functional interactions with histone H3. Our results show that the Spt16-M domain plays a role in the prevention of cryptic intragenic transcription during transcription elongation and also suggest that the Spt16-M domain has a function in regulating dissociation of Spt16 from chromatin at the end of the transcription process. We also provide evidence for a role for the extreme carboxy terminus of Spt16 in functional interactions with histone H3. Taken together, our studies point to previously undescribed roles for the Spt16 M-domain and extreme carboxy terminus in regulating interactions between Spt16 and chromatin during the process of transcription elongation
Multi Centricity of Oral Verrucous Carcinoma: A Case Series of 22 Cases
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A masked initiation region in retinoblastoma protein regulates its proteasomal degradation
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Reliability of Incision Biopsy for Diagnosis of Oral Verrucous Carcinoma: A Multivariate Clinicopathological Study
- Author
- A Alkan
- A Ferlito
- A Ogawa
- BB Koch
- DP Slaughter
- EA Fonts
- GL Ross
- HBE Klieb
- JA Woolgar
- Jesus E Medina
- JG Batsakis
- JJ Pindborg
- JL Kasperbauer
- JM McCoy
- John G Batsakis
- K Tornes
- K. A. Jeevan Kumar
- K. V. V. N. Raju
- L Ackerman
- L. M. Chandrasekhara Rao
- LR Eversole
- M Shear
- ME Tharp II
- Nagendra Parvataneni
- P Radkani
- Pieter J Slootweg
- Ravi Chander
- S Jacobson
- Sandhya Gokavarapu
- SDE Demian
- Sujit Chau Patnaik
- T Saito
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Verrucous Carcinoma with Dysplasia or Minimal Invasion: A Variant of Verrucous Carcinoma with Extremely Favorable Prognosis
- Author
- A Ferlito
- A Ferlito
- A Kolokythas
- AF Jahn
- AS Masih
- BB Koch
- C-J Kang
- CA Perez
- DT Oliveira
- EA Fonts
- FL Durden
- FT Kraus
- James S. Lewis
- JE Medina
- JG Batsakis
- JS McDonald
- K Chandler
- Kalyani R. Patel
- KP Rekha
- LJ Orvidas
- LV Ackerman
- MS Vidyasagar
- N Johnson
- P Strojan
- P Strojan
- Parul Sinha
- R Cerero-Lapiedra
- R Jyothirmayi
- Rebecca D. Chernock
- RR Walvekar
- S Chuanyu
- S Larsen
- S-Y An
- Samir K. El-Mofty
- SD Demian
- Susan Müller
- Y Yoshimura
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Röntgenschäden
- Author
- A Bachem
- A Bachem
- A Bock
- A Brandt
- A Costa
- A Costa
- A Crevoisier
- A Czepa
- A Determann
- A Determann
- A Determann
- A Determann
- A Dombrovskij
- A Dombrovskij
- A Druckmann
- A Döderlein
- A Döderlein
- A Engelhard
- A Filatov
- A Frank
- A Hautant
- A Jugenburg
- A Jugenburg
- A Kahlstorff
- A Kahlstorff
- A Köhler
- A Köhler
- A Köhler
- A Köhler
- A Lacassagne
- A Lorey
- A Lorey
- A Lorey
- A Lorey
- A Ludwig
- A Mutscheller
- A Pokorny
- A Reisner
- A Reisner
- A Reisner
- A Reisner
- A Reisner
- A Reisner
- A Reisner
- A Reyn
- A Reyn
- A Richarz
- A Rost
- A Simons
- A Simons
- A Simons
- A Springer
- A Springer
- A Waegner
- A Wagner
- A Wagner
- A Wierig
- A Zollinger
- AA Thibaudeau
- AE Barclay
- AEL Dean
- AH Roffo
- AH Roffo
- AH Roffo
- AH Roffo
- AH Roffo
- Albers-Schönberg
- Albers-Schönberg
- Albers-Schönberg
- Albers-Schönberg
- Albers-Schönberg
- Albers-Schönberg
- Alberti
- Alberti
- Albrecht
- Altschul
- Altschul
- Amersbach
- Amersbach
- Amersbach
- Andersen
- Andrews
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- Apostoli
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- AU Desjardins
- AU Desjardins
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- AW Siehe
- B Aulamo
- B Aulamo
- B Aulamo
- B Bloch
- B Bloch
- B Bloch
- B Bloch
- B Droste
- B Gaβmann
- B Glocker
- B Glocker
- B Hickey
- B Jaksch-Wartenhorst
- B Kelen
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- B Walter
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- Bernhardt
- Berthold
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- Die ultravioletten Strahlen als Prophylaktikum gegen Röntgendermatitis
- Dietel
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- G Backer de
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- Gabriel
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1935
- Field of study
Physiologie und Pathologie des Renin/Angiotensin-Systems
- Author
- A Beaulnes
- A Bianchi
- A Blalock
- A Blalock
- A Bohle
- A Bohle
- A Breckenridge
- A Distler
- A Divry
- A Eisalo
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- A Freedman
- A Girolami
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- A Huvos
- A Kaplan
- A Kumagai
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- A Merrill
- A Orollmann
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- A Verniory
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- PJ Mulrow
- PJ Mulrow
- PJ Mulrow
- PJ Mulrow
- PM Daniel
- PM Daniel
- PM Hartroft
- PM Hartroft
- PM Hartroft
- PM Hartroft
- PM Hartroft
- PM Hartroft
- PM Hartroft
- PM Hartroft
- PN Yu
- PP Leyssac
- PP Leyssac
- PP Leyssac
- PP Leyssac
- PP Moraea
- PT Pickens
- PY Hatt
- PY Hatt
- PY Hatt
- PY Hatt
- PY Hatt
- R Abdul-Karim
- R Boucher
- R Boucher
- R Boucher
- R Boucher
- R Boucher
- R Cade
- R Croxatto
- R DeRoos
- R Edelman
- R Edelman
- R Eraser
- R Gaunt
- R Gaunt
- R Gaunt
- R Gregory
- R Gregory
- R Hegglin
- R Heintz
- R Hess
- R Hess
- R Hess
- R Jaques
- R Laverty
- R Lenel
- R Meier
- R Meier
- R Meier
- R Poro Del
- R Sannerstedt
- R Schröder
- R Schröder
- R Schwyzer
- R Schwyzer
- R Schwyzer
- R Schwyzer
- R Schwyzer
- R Tigerstedt
- R Veyrat
- R Veyrat
- R Veyrat
- R Veyrat
- R Veyrat
- R Wedeen
- R Weiser
- R Yu
- R.R. Smeby
- RB Blacket
- RB Hickler
- RB Hickler
- RB Hickler
- RB Hickler
- RB Hickler
- RC Lillehei
- RC Nairn
- RD Bunag
- RD Cressman
- RD Gordon
- RD Gordon
- RD Gordon
- RD Moore
- RE Morris
- RE Morris
- RE Morris
- RG Abell
- RG Abell
- RH Harris
- RH Heptinstall
- RH Heptinstall
- RJ Cohen
- RJ Girerd
- RJ Girerd
- RK Bickerton
- RK Jones
- RL Hodge
- RL Hodge
- RL Malvin
- RL Wathen
- RL Wolf
- RM Boughton
- RM Stein
- RM Tucker
- RP Ames
- RP Finegan
- RR Smeby
- RR Smeby
- RR Smeby
- RR Susat
- RT Curnow
- RT Solis
- S Chandra
- S Chandra
- S Fukuchi
- S Giovannetti
- S Glabman
- S Gomba
- S Koletsky
- S Koletsky
- S Koletsky
- S Koletsky
- S Koletsky
- S Middleton
- S Moore
- S Rodbard
- S Rodbard
- S Rosenfeld
- S Rothman
- S Schapiro
- S Yagi
- S Yagi
- SC Freed
- SC Freed
- SD Deodhar
- SD Deodhar
- SD Deodhar
- SD Deodhar
- SE Bradley
- SE Downing
- SE Moutsos
- SH Kremen
- SL Skinner
- SL Skinner
- SL Skinner
- SL Skinner
- SL Skinner
- SM Friedman
- SM Friedman
- SM Friedman
- SM Friedman
- SM Friedman
- SM Friedman
- SM Friedman
- SM Sancetta
- SW Hoobler
- SW Hoower
- T Addis
- T Addis
- T Addis
- T Lehner
- T Omae
- T Omae
- T Omae
- T Torikai
- TA Stamey
- TA Stamey
- TA Stamey
- TC Brown
- TC Brown
- TC Lee
- TC Lee
- TC Westfall
- TE Emerson
- TF Ferris
- TL Goodfriend
- TL Goodfriend
- TL Goodfriend
- TR Harrison
- TR Harrison
- TR Harrison
- TUL Biber
- V Szokoly
- V Vertes
- VN Udhoji
- VN Udhoji
- W Brumfitt
- W Brumiitt
- W Dock
- W Dock
- W Feldberg
- W Feldberg
- W Feldberg
- W Meesmann
- W Nowaczynski
- W Rittel
- W Rittel
- W Waldhäusl
- WA Mersereau
- WB Berry
- WB Severs
- WC Poque
- WD Davis
- WD Love
- WD Reid
- WE Goorno
- WE Goorno
- WE Goorno
- WE Judson
- WE Lassiter
- WF Cook
- WF Cook
- WF Cook
- WF Cook
- WF Cook
- WF Cook
- WF Ganong
- WF Ganong
- WF Ganong
- WF Ganong
- WF Ganong
- WF Greenwood
- WF Oanong
- WG Kubicek
- WH Pritchard
- WH Tu
- WH Tu
- WJ Kolff
- WJ Kolff
- WJ Kolff
- WJ Kolff
- WJ Oliver
- WJ Oliver
- WL Brandt
- WP Johnson
- WS Hartroft
- WS Hartroft
- WS Kiser
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WS Peart
- WT Williams
- Y Cuypers
- YJ Katz
- YJ Katz
- YJ Katz
- YJ Katz
- ZM Massani
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1968
- Field of study