975 research outputs found
Порівняльний аналіз систем для ранжирування українських наукових періодичних видань та їхніх складових
Проаналізовано відомі бази даних наукових публікацій і рейтинги наукових публікацій, окремих науковців, наукових журналів та окремих галузей науки. Запропоновано інфологічну модель і бізнес-правила бази даних наукових публікацій. На її основі запропоновано метод розрахунку вебометричного рейтингу наукових публікацій, авторів, організацій, журналів.Проанализированы известные базы данных научных публикаций и рейтинги научных публикаций, отдельных ученых, научных журналов и отдельных направлений науки. Предложена инфологическая модель и бизнес-правила базы данных научных публикаций. На ее основе предложен метод расчета вебометрического рейтинга научных публикаций, авторов, организаций, журналов.The known databases of scientific publications and the rating of scientific publications, certain scientists, scientific journals and certain fields of science are analyzed. The infological model and the business rules of scientific publications database are proposed. The computing method of webometrics rating of scientific publications, authours, journals and organizations is proposed
Colloid-oil-water-interface interactions in the presence of multiple salts: charge regulation and dynamics
We theoretically and experimentally investigate colloid-oil-water-interface
interactions of charged, sterically stabilized, poly(methyl-methacrylate)
colloidal particles dispersed in a low-polar oil (dielectric constant
) that is in contact with an adjacent water phase. In this model
system, the colloidal particles cannot penetrate the oil-water interface due to
repulsive van der Waals forces with the interface whereas the multiple salts
that are dissolved in the oil are free to partition into the water phase. The
sign and magnitude of the Donnan potential and/or the particle charge is
affected by these salt concentrations such that the effective interaction
potential can be highly tuned. Both the equilibrium effective colloid-interface
interactions and the ion dynamics are explored within a Poisson-Nernst-Planck
theory, and compared to experimental observations.Comment: 13+2 pages, 5+3 figures; V2: small clarifications in the tex
CO2 budgeting at the regional scale using a Lagrangian experimental strategy and meso-scale modeling
An atmospheric Lagrangian experiment for regional CO2 budgeting with aircraft measurements took place during the CarboEurope Regional Experiment Strategy campaign (CERES) in south-west France, in June 2005. The atmospheric CO2 aircraft measurements taken upstream and downstream of an active and homogeneous pine forest revealed a CO2 depletion in the same air mass, using a Lagrangian strategy. This field experiment was analyzed with a meteorological meso-scale model interactively coupled with a surface scheme, with plant assimilation, ecosystem respiration, anthropogenic CO2 emissions and sea fluxes. First, the model was carefully validated against observations made close to the surface and in the atmospheric boundary layer. Then, the carbon budget was evaluated using the numerous CERES observations, by upscaling the surface fluxes observations, and using the modeling results, in order to estimate the relative contribution of each physical process. A good agreement is found between the two methods which use the same vegetation map: the estimation of the regional CO2 surface flux by the Eulerian meso-scale model budget is close to the budget deduced from the upscaling of the observed surface fluxes, and found a budget between −9.4 and −12.1μmol.m−2.s−1, depending on the size of the considered area. Nevertheless, the associated uncertainties are rather large for the upscaling method and reach 50%. A third method, using Lagrangian observations of CO2 estimates a regional CO2 budget a few different and more scattered, (−16.8μmol.m−2.s−1 for the small sub-domain and −8.6μmol.m−2.s−1 for the larger one). For this budgeting method, we estimate a mean of 31% error, mainly arising from the time of integration between the two measurements of the Lagrangian experiment. The paper describes in details the three methods to assess the regional CO2 budget and the associated error
Genome-wide diversity and global migration patterns in dromedaries follow ancient caravan routes
Dromedaries have been essential for the prosperity of civilizations in arid environments and the dispersal of humans, goods and cultures along ancient, cross-continental trading routes. With increasing desertification their importance as livestock species is rising rapidly, but little is known about their genome-wide diversity and demographic history. As previous studies using few nuclear markers found weak phylogeographic structure, here we detected fine-scale population differentiation in dromedaries across Asia and Africa by adopting a genome-wide approach. Global patterns of effective migration rates revealed pathways of dispersal after domestication, following historic caravan routes like the Silk and Incense Roads. Our results show that a Pleistocene bottleneck and Medieval expansions during the rise of the Ottoman empire have shaped genome-wide diversity in modern dromedaries. By understanding subtle population structure we recognize the value of small, locally adapted populations and appeal for securing genomic diversity for a sustainable utilization of this key desert species
О финансово-экономическом кризисе
У статті для визначення позиції молодих учених, стосовно фінансово-економічної кризи 2008–2010 р. використаний метод нечіткої кластеризації даних, що працює в режимі паралельної їхньої обробки. Наведено заходи щодо зниження наслідків кризи для України.В статье для определения позиции молодых ученых, применительно к финансово-экономическому кризису 2008—2010 гг. использован метод нечеткой кластеризации данных, который работает в режиме параллельной их обработки. Приведены мероприятия по снижению последствий кризиса для Украины.In an article for determining the position of young scientists, in relation to financial and economic crisis, 2008— 2010. used the method of fuzzy clustering, which operates in parallel processing. Shows the measures to reduce the impact of the crisis in Ukraine
Geo-additive models of Childhood Undernutrition in three Sub-Saharan African Countries
We investigate the geographical and socioeconomic determinants of childhood undernutrition in Malawi, Tanzania and Zambia, three neighboring countries in Southern Africa using the 1992 Demographic and Health Surveys. We estimate models of undernutrition jointly for the three countries to explore regional patterns of undernutrition that transcend boundaries, while allowing for country-specific interactions. We use semiparametric models to flexibly model the effects of selected so-cioeconomic covariates and spatial effects. Our spatial analysis is based on a flexible geo-additive model using the district as the geographic unit of anal-ysis, which allows to separate smooth structured spatial effects from random effect. Inference is fully Bayesian and uses recent Markov chain Monte Carlo techniques. While the socioeconomic determinants generally confirm what is known in the literature, we find distinct residual spatial patterns that are not explained by the socioeconomic determinants. In particular, there appears to be a belt run-ning from Southern Tanzania to Northeastern Zambia which exhibits much worse undernutrition, even after controlling for socioeconomic effects. These effects do transcend borders between the countries, but to a varying degree. These findings have important implications for targeting policy as well as the search for left-out variables that might account for these residual spatial patterns
Improving Illumina assemblies with Hi-C and long reads : An example with the North African dromedary
Researchers have assembled thousands of eukaryotic genomes using Illumina reads, but traditional mate-pair libraries cannot span all repetitive elements, resulting in highly fragmented assemblies. However, both chromosome conformation capture techniques, such as Hi-C and Dovetail Genomics Chicago libraries and long-read sequencing, such as Pacific Biosciences and Oxford Nanopore, help span and resolve repetitive regions and therefore improve genome assemblies. One important livestock species of arid regions that does not have a high-quality contiguous reference genome is the dromedary (Camelus dromedarius). Draft genomes exist but are highly fragmented, and a high-quality reference genome is needed to understand adaptation to desert environments and artificial selection during domestication. Dromedaries are among the last livestock species to have been domesticated, and together with wild and domestic Bactrian camels, they are the only representatives of the Camelini tribe, which highlights their evolutionary significance. Here we describe our efforts to improve the North African dromedary genome. We used Chicago and Hi-C sequencing libraries from Dovetail Genomics to resolve the order of previously assembled contigs, producing almost chromosome-level scaffolds. Remaining gaps were filled with Pacific Biosciences long reads, and then scaffolds were comparatively mapped to chromosomes. Long reads added 99.32 Mbp to the total length of the new assembly. Dovetail Chicago and Hi-C libraries increased the longest scaffold over 12-fold, from 9.71 Mbp to 124.99 Mbp and the scaffold N50 over 50-fold, from 1.48 Mbp to 75.02 Mbp. We demonstrate that Illumina de novo assemblies can be substantially upgraded by combining chromosome conformation capture and long-read sequencing.Peer reviewe
The Impact of a Pulmonary-Artery-Catheter-Based Protocol on Fluid and Catecholamine Administration in Early Sepsis
Objective. The pulmonary artery catheter (PAC) remains topic of debate. Despite abundant data, it is of note that many trials did not incorporate a treatment protocol.
Methods. We retrospectively evaluated fluid balances and catecholamine doses in septic patients after the introduction of a PAC-based treatment protocol in comparison to historic controls. Results. 2 × 70 patients were included. The first day the PAC group had a significantly higher positive fluid balance in comparison to controls (6.1 ± 2.6 versus 3.8 ± 2.4 litre, P < 0.001). After 7 days the cumulative fluid balance in the PAC group was significantly lower than in controls (9.4 ± 7.4 versus 13 ± 7.6 litre, P = 0.001). Maximum dose of norepinephrine was significantly higher in the PAC group. Compared to controls this was associated with a significant reduction in ventilator and ICU days. Conclusions. Introduction of a PAC-based treatment protocol in sepsis changed the administration of fluid and vasopressors significantly
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