Extensión Mylyn para Reuniones de Revisión de Proyecto

El objetivo de este trabajo consiste en la construcción de una herramienta que permita hacer más fácil, eficiente y objetiva la realización de reuniones de revisión de proyecto, procesos de seguimiento que se suceden de manera regular durante el desarrollo de un proyecto software y que consisten en el análisis de una serie de datos y estadísticas que proporcionen la información suficiente para valorar el estado de un proyecto en un momento dado. De este modo se puede realizar un seguimiento objetivo del mismo y replanificar u organizar de manera eficiente los recursos disponibles para su desarrollo, adaptando y ajustando el proyecto según las necesidades o imprevistos que surjan. La herramienta RRP se ha desarrollado sobre Eclipse, que es una de las plataformas libres de desarrollo de software más usadas en todo el mundo, e incorpora un framework de gestión de ciclo de vida de proyectos software de código libre, denominado Mylyn, cada vez más popular. Se trata de un proyecto conocido, que cuenta con un gran número de contribuidores que hacen que crezca funcionalmente día tras días. Con este objetivo y con Eclipse y Mylyn como entornos nace la herramienta RRP, Reunión de Revisión de Proyecto. RRP se ha desarrollado como extensión de Mylyn, también de código libre, y al alcance de toda persona que quiera añadir esta nueva funcionalidad a su sistema. RRP utiliza toda la información disponible que almacena Mylyn para poder reunir una serie de datos y calcular todo tipo de estadísticas que puedan ser de utilidad en una reunión de revisión de proyecto. El resultado de su ejecución es un informe en formato HTML, legible en cualquier navegador web. Se ha realizado un análisis de los diferentes protocolos que actualmente existen y que ofrecen procedimientos para realizar reuniones de revisión de proyecto de calidad, así como de las herramientas de pago que realizan algunas funciones similares. RRP se ha diseñado de acuerdo al estilo de Mylyn, manteniendo una interfaz simple y clara. Internamente se ha implementado un código legible y fácil de entender, con el propósito de que otras personas lo puedan utilizar para desarrollar nueva funcionalidad. El conjunto de funcionalidades del sistema se encuentra en un paquete dentro de uno de los proyectos que componen Mylyn. Finalmente, se han realizado un conjunto de pruebas unitarias y de integración para verificar y validar el sistema obteniendo resultados satisfactorios. Además, distintos usuarios han evaluado -positivamente la herramienta-, y han sugerido el añadir algunas funcionalidades nuevas. La versión resultante de este trabajo, realizado íntegramente por la estudiante Lara Domínguez, es una primera versión de la herramienta totalmente operativa, a falta de poder añadirla al repositorio oficial de Eclipse de extensiones de Mylyn.The aim of this work is to build a tool that makes the realization of project review meetings easier, more efficient and more objective. The project review meetings are tracking process that occur regularly during the development of a software project which consist on analyzing a set of data and statistics that provide enough information to evaluate the status of a project at any given time. In this way, you can keep track of the project and replan or organize efficiently the resources available for the development of it, adapting and adjusting the project according to the needs or contingencies that arise. This tool, called RRP, has been developed in Eclipse, that is one of the free software development platforms most commonly used in the world, and incorporates an open-source framework of lifecycle management of software projects, called Mylyn, increasingly popular. It is a known project, which has a large number of contributors who work hard to make functionally grow day after day. With this aim and using Eclipse and Mylyn as development environments, was born the RRP tool, Project Review Meeting (acronym in Spanish). RRP has been developed as an extension of Mylyn, also open-source, and available to anyone who wants to add new functionality to their system. RRP uses all available information stored by Mylyn to collect certain information and calculate all kinds of statistics that can be useful in a project review meeting. The result of its execution is a report in HTML format, readable on any web browser. It has done an analysis of the different protocols that currently exist and provide procedures for do project review meetings with high quality, as well as payment tools that perform some similar functions. RRP has been designed according to the style of Mylyn, keeping a simple and clear interface. Internally it has been implemented a code easy-readable and easy to understand, in order that other contributors may use it to develop new functionality. The feature set of the system is in a package in one of the projects that make up Mylyn. Finally, it has been made a set unitary and integration tests to verify and validate the system obtaining satisfactory results. In addition, different users have evaluated -positively the tool-, and they have suggested adding others new ones. The resulting version of this work, which it has been done entirely by the student Lara Dominguez, is the first version of the fully operational tool, but waiting to add it to the official repository of Eclipse Mylyn extensions

Inside the Outbreak of the 2009 Influenza A (H1N1)v Virus in Mexico

Influenza viruses pose a threat to human health because of their potential to cause global disease. Between mid March and mid April a pandemic influenza A virus emerged in Mexico. This report details 202 cases of infection of humans with the 2009 influenza A virus (H1N1)v which occurred in Mexico City as well as the spread of the virus throughout the entire country.From May 1st to May 5th nasopharyngeal swabs, derived from 751 patients, were collected at 220 outpatient clinics and 28 hospitals distributed throughout Mexico City. Analysis of samples using real time RT-PCR revealed that 202 patients out of the 751 subjects (26.9%) were confirmed to be infected with the new virus. All confirmed cases of human infection with the strain influenza (H1N1)v suffered respiratory symptoms. The greatest number of confirmed cases during the outbreak of the 2009 influenza A (H1N1)v were seen in neighbourhoods on the northeast side of Mexico City including Iztapalapa, Gustavo A. Madero, Iztacalco, and Tlahuac which are the most populated areas in Mexico City. Using these data, together with data reported by the Mexican Secretariat of Health (MSH) to date, we plot the course of influenza (H1N1)v activity throughout Mexico.Our data, which is backed up by MSH data, show that the greatest numbers of the 2009 influenza A (H1N1) cases were seen in the most populated areas. We speculate on conditions in Mexico which may have sparked this flu pandemic, the first in 41 years. We accept the hypothesis that high population density and a mass gathering which took in Iztapalapa contributed to the rapid spread of the disease which developed in three peaks of activity throughout the Country

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe

Measurement of prompt open-charm production cross sections in proton-proton collisions at root s=13 TeV

The production cross sections for prompt open-charm mesons in proton-proton collisions at a center-of-mass energy of 13TeV are reported. The measurement is performed using a data sample collected by the CMS experiment corresponding to an integrated luminosity of 29 nb(-1). The differential production cross sections of the D*(+/-), D-+/-, and D-0 ((D) over bar (0)) mesons are presented in ranges of transverse momentum and pseudorapidity 4 < p(T) < 100 GeV and vertical bar eta vertical bar < 2.1, respectively. The results are compared to several theoretical calculations and to previous measurements.Peer reviewe

Measurement of B-c(2S)(+) and B-c*(2S)(+) cross section ratios in proton-proton collisions at root s=13 TeV

Peer reviewe

Development and validation of HERWIG 7 tunes from CMS underlying-event measurements

This paper presents new sets of parameters (“tunes”) for the underlying-event model of the HERWIG7 event generator. These parameters control the description of multiple-parton interactions (MPI) and colour reconnection in HERWIG7, and are obtained from a fit to minimum-bias data collected by the CMS experiment at s=0.9, 7, and 13Te. The tunes are based on the NNPDF 3.1 next-to-next-to-leading-order parton distribution function (PDF) set for the parton shower, and either a leading-order or next-to-next-to-leading-order PDF set for the simulation of MPI and the beam remnants. Predictions utilizing the tunes are produced for event shape observables in electron-positron collisions, and for minimum-bias, inclusive jet, top quark pair, and Z and W boson events in proton-proton collisions, and are compared with data. Each of the new tunes describes the data at a reasonable level, and the tunes using a leading-order PDF for the simulation of MPI provide the best description of the dat

Measurement of the W gamma Production Cross Section in Proton-Proton Collisions at root s=13 TeV and Constraints on Effective Field Theory Coefficients

A fiducial cross section for W gamma production in proton-proton collisions is measured at a center-of-mass energy of 13 TeV in 137 fb(-1) of data collected using the CMS detector at the LHC. The W -> e nu and mu nu decay modes are used in a maximum-likelihood fit to the lepton-photon invariant mass distribution to extract the combined cross section. The measured cross section is compared with theoretical expectations at next-to-leading order in quantum chromodynamics. In addition, 95% confidence level intervals are reported for anomalous triple-gauge couplings within the framework of effective field theory.Peer reviewe

Reconstruction of signal amplitudes in the CMS electromagnetic calorimeter in the presence of overlapping proton-proton interactions

A template fitting technique for reconstructing the amplitude of signals produced by the lead tungstate crystals of the CMS electromagnetic calorimeter is described. This novel approach is designed to suppress the contribution to the signal of the increased number of out-of-time interactions per beam crossing following the reduction of the accelerator bunch spacing from 50 to 25 ns at the start of Run 2 of the LHC. Execution of the algorithm is sufficiently fast for it to be employed in the CMS high-level trigger. It is also used in the offline event reconstruction. Results obtained from simulations and from Run 2 collision data (2015-2018) demonstrate a substantial improvement in the energy resolution of the calorimeter over a range of energies extending from a few GeV to several tens of GeV.Peer reviewe

Observation of the Production of Three Massive Gauge Bosons at root s=13 TeV

The first observation is reported of the combined production of three massive gauge bosons (VVV with V = W, Z) in proton-proton collisions at a center-of-mass energy of 13 TeV. The analysis is based on a data sample recorded by the CMS experiment at the CERN LHC corresponding to an integrated luminosity of 137 fb(-1). The searches for individualWWW, WWZ, WZZ, and ZZZ production are performed in final states with three, four, five, and six leptons (electrons or muons), or with two same-sign leptons plus one or two jets. The observed (expected) significance of the combinedVVV production signal is 5.7 (5.9) standard deviations and the corresponding measured cross section relative to the standard model prediction is 1.02(-0.23)(+0.26). The significances of the individual WWW and WWZ production are 3.3 and 3.4 standard deviations, respectively. Measured production cross sections for the individual triboson processes are also reported