The psychosocial burden of hidradenitis suppurativa: the patients' perspectives

We designed a qualitative study to interview 12 patients with Hidradenitis Suppurativa. This was done by means of a semistructured interview. Questions on quality of life, the impact of their skin disease on family, friends, work, intimate relationships, treatments, etc. were asked. Patients consented to be interviewed and to be video taped to facilitate the transcription of the interviews. The interviews lasted between 30 and 60 minutes and were carried out by a psychologist and a social worker. The dermatologist had previously seen the patients and filled in a form with the Hurley Stage, years of evolution and treatment..

Solutions of the dispersion equation in the region of overlapping of zero-sound and particle-hole modes

In this paper the solutions of the zero-sound dispersion equation in the random phase approximation (RPA) are considered. The calculation of the damped zero-sound modes \omega_s(k) (complex frequency of excitation) in the nuclear matter is presented. The method is based on the analytical structure of the polarization operators \Pi(\omega,k). The solutions of two dispersion equations with \Pi(\omega,k) and with Re(\Pi(\omega,k)) are compared. It is shown that in the first case we obtain one-valued smooth solutions without "thumb-like" forms. Considering the giant resonances in the nuclei as zero-sound excitations we compare the experimental energy and escape width of the giant dipole resonance (GDR) in the nucleus A with \omega_s(k) taken at a definite wave vector k=k_A.Comment: 14 pages, 5 figures; revised versio

Fiabilidad y validez de constructo del test MUNSH para medir felicidad, en población de adultos mayores chilenos

Diaz, EM (reprint author), Univ Talca, Fac Psicol, Casilla 747, Talca, Chile.The goal was to adapt and to conduct the preliminary validation of the Scale of Happiness of the Memorial University of Newfounland (MUNSH). Three hundred elderly (Maule, Chile) of more than 65 years (M = 72,8; DS = 5,71), answered the MUNSH, the Life Satisfaction Scale of Diener (ESV), and the Abbreviated Geriatric Depression Scale of Yesavage (EGADY). The MUNSH reached a Cronbach's alpha consistency of 0.90, and correlated positively with the ESV (r = 0.623) and negatively with the EGADY (r = -0.746), demonstrating appropriate convergent validity. A factor analysis revealed a multifactorial structure for the MUNSH with a single factor explaining 31,7 % of the variance. The data collected with the MUNSH are analyzed in terms of age and sex differences and separate normative scores are provided. Accession Number: WOS:00029970900002

Patrón de comportamiento tipo A, ira y enfermedades cardiovasculares (ECV) en población urbana chilena

Diaz, EM (Moyano Diaz, Emilio)1; Icaza, G (Icaza, Gloria); Mujica, V (Mujica, Veronica); Nunez, L (Nunez, Loreto); Leiva, E (Leiva, Elba); Vasquez, M (Vasquez, Marcela); Palomo, I (Palomo, Ivan)A worldwide raise in the number of cardiovascular disease (CVD) and the existence of a higher percentage in Maule (Chile) than the national media, and increased attention in the analysis of psychological factors motivate to analyze the Type A Behavior Pattern (TABP) and anger in relation to CVD. The sample was 1007 adults between 18 and 74 years old (citizens of Talca, Chile), mostly women. They provided information about their demographic details, eating habits and lifestyle, answered the Novaco's Anger inventory and the Retiro Scale of Type A Behavior (RSTAB), and also were taken measurements like weight, body mass index and blood pressure and blood tests related to risk factors to traditional cardiovascular diseases. The results show Overall, that the participants appear highly sedentary (79.9%) with relatively high levels of tabaquism (53.6%), and hypercholesterolemia (44.5%), overweight (40.7%) and obesity (32.6%). A quarter of the sample also presents hyperglycemic indexes, hypertension and TABP unequally distributed by sex. The absence of PCTA (or PCTB presence) appeared mostly associated with traditional cardiovascular risk factors (CRF). Regarding anger, women present more high than men (2.1% against 0.3%; c(2)(3) = 27.99,p<.0001), decreasing for both sexes with age, while also befall stroke by sex

The Orbit of the New Milky Way Globular Cluster FSR1716 =VVV-GC05

Indexación: Scopus.We use deep, multi-epoch near-IR images of the VISTA Variables in the Via Lictea (VVV) Survey to measure proper motions (PMs) of stars in the Milky Way globular cluster (GC) FSR1716 = VVV-GC05. The colormagnitude diagram of this object, made by using PM-selected members, shows an extended horizontal branch, nine confirmed RR Lyrae (RRL) members in the instability strip, and possibly several hotter stars extending to the blue. Based on the fundamental-mode (ab-type) RRL stars that move coherently with the cluster, we confirmed that FSR1716 is an Oosterhoff I GC with a mean period aPabn = 0.574 days. Intriguingly, we detect tidal extensions to both sides of this cluster in the spatial distribution of PM-selected member stars. Also, one of the confirmed RRabs is located -11 arcmin in projection from the cluster center, suggesting that FSR1716 may be losing stars due to the gravitational interaction with the Galaxy. We also measure radial velocities (RVs) for five cluster red giants selected using the PMs. The combination of RVs and PMs allow us to compute for the first time the orbit of this GC, using an updated Galactic potential. The orbit results to be confined within|Zmax| < 2.0 kpc, and has eccentricity 0.4 < e < 0.6, with perigalactic distance 1.5 < Rperi (kpc) < 2.3, and apogalactic distance 5.3 < Rapo (kpc) < 6.4. We conclude that, in agreement with its relatively low metallicity ([Fe/H] =-1.4 dex), this is an inner-halo GC plunging into the disk of the Galaxy. As such, this is a unique object with which to test the dynamical processes that contribute to the disruption of Galactic GCs. © 2018. The American Astronomical Society. All rights reserved.https://iopscience.iop.org/article/10.3847/1538-4357/aacd0

6Li direct breakup lifetimes

alpha-d coincidence data were studied for the 6Li + 59Co reaction at E(lab) = 29.6 MeV. By using a kinematic analysis, it was possible to identify which process, leading to the same final state, has the major contribution for each of the selected angular regions. Contributions of the 6Li sequential and direct breakup to the incomplete fusion/transfer process were discussed by considering the lifetimes obtained by using a semiclassical approach, for both breakup components.Comment: 5 pages, 4 figures, Invited Talk (Parrallel Sessions) of A. Szanto de Toledo, prepared for the Proccedings of the 10th International Conference on Nucleus-Nucleus Collisions, August 16-21, 2009, Beijing, China; submitted to Nucl. Phys. A (Proceedings of NN2009

Reaction mechanisms for weakly-bound, stable nuclei and unstable, halo nuclei on medium-mass targets

An experimental overview of reactions induced by the stable, but weakly-bound nuclei 6Li, 7Li and 9Be, and by the exotic, halo nuclei 6He, 8B, 11Be and 17F on medium-mass targets, such as 58Ni, 59Co or 64Zn, is presented. Existing data on elastic scattering, total reaction cross sections, fusion processes, breakup and transfer channels are discussed in the framework of a CDCC approach taking into account the breakup degree of freedom.Comment: 7 pages, 6 figures, Invited Talk given by C. Beck to the 10th International Conference on Nucleus-Nucleus Collisions, August 16-21, 2009 Beijing, China; Paper submitted to the NN2009 Proceedings, Nuclear Physics A (to be published

Coagulation Parameters: An Efficient Measure for Predicting the Prognosis and Clinical Management of Patients with COVID-19

Background. COVID-19 is an ongoing global pandemic. Since the detection of the first cases of coronavirus disease 2019 (COVID-19) in Wuhan, China, the current pandemic has affected more than 25.3 million people worldwide. The aim of this study was to evaluate the relationship between coagulation abnormalities and prognosis in a cohort of patients with COVID-19. Methods. We performed a retrospective cohort study of 3581 patients admitted to Hospital La Paz (Madrid, Spain) due to respiratory infection by severe acute respiratory syndrome coronavirus from the beginning of the current pandemic to 15 July 2020. Results. Of the 3581 study patients, 48.94% were men, and 19.80% were healthcare workers. The median age was 62 years. Compared with the survivors, the non-survivors had lower prothrombin activity (82.5 (Interquartile range-IQR, 67-95) vs. 95.25 (IQR, 87-104) for non-survivors and survivors, respectively; p < 0.001), higher fibrinogen levels (748.5-IQR, 557-960) vs. 572.75 (IQR, 417-758; p < 0.001), and notably higher D-dimer levels (2329-IQR, 1086.12-5670.40) vs. 635.5 (IQR, 325.5-1194.8); p < 0.001). Conclusions. The evaluation of coagulation parameters could be an efficient measure for predicting the prognosis and improving the clinical management of patients with COVID-19

Reactivation of ancestral strains of HIV-1 in the gp120 V3 env region in patients failing antiretroviral therapy and subjected to structured treatment interruption

We analyzed gp120V3 HIV-1 env region genetic diversity of 27 patients failing antiretrovirals and subjected to 12-week structured treatment interruption (STI). Based on heteroduplex mobility assays, eight patients presented low pre- and post-STI genetic diversity (G1); five presented high pre-STI but low post-STI diversity (G2); five presented low pre-STI and high post-STI diversity (G3); and nine, high pre- and post-STI diversity (G4). One patient from G1, two from G2 and two from G3 were subjected to proviral DNA end-point PCR and sequencing. in three patients, the dramatic disturbance caused by STI resulted in ancestral viral progeny activation, which repopulated the cell reservoir. in two patients presenting highly homogeneous sequences and low immune selective pressure (dN/dS ratio < 1), this phenomenon was not observed. the mechanisms involved in viral evolution, in which antiretroviral therapy also applies selective pressure, sometimes affects coreceptor usage of circulating viruses, leading to the suppression of x4 strains. (c) 2006 Published by Elsevier Inc.Universidade Federal de São Paulo, Escola Paulista Med, Lab Retrovirol, BR-04039032 São Paulo, BrazilFundacao Pro Sangue, BR-05403000 São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Lab Retrovirol, BR-04039032 São Paulo, BrazilWeb of Scienc

On Isotropic Turbulence in the Dark Fluid Universe

As first part of this work, experimental information about the decay of isotropic turbulence in ordinary hydrodynamics, u^2(t) proportional to t^{-6/5}, is used as input in FRW equations in order to investigate how an initial fraction f of turbulent kinetic energy in the cosmic fluid influences the cosmological development in the late, quintessence/phantom, universe. First order perturbative theory to the first order in f is employed. It turns out that both in the Hubble factor, and in the energy density, the influence from the turbulence fades away at late times. The divergences in these quantities near the Big Rip behave essentially as in a non-turbulent fluid. However, for the scale factor, the turbulence modification turns out to diverge logarithmically. As second part of our work, we consider the full FRW equation in which the turbulent part of the dark energy is accounted for by a separate term. It is demonstrated that turbulence occurrence may change the future universe evolution due to dissipation of dark energy. For instance, phantom-dominated universe becomes asymptotically a de Sitter one in the future, thus avoiding the Big Rip singularity.Comment: 10 pages, no figures, significant revision. Matches published versio