Impact of Malaria Severity on Selected Liver Function Markers in Aden, Yemen: A Pilot Study

Background: Malaria remains a significant public health concern, with Plasmodium falciparum and P. vivax infections often leading to systemic complications, including hepatic dysfunction. Objective: This study investigates the relationship between malaria severity and liver function abnormalities, particularly bilirubin and liver enzyme elevations, in malaria patients in Aden, Yemen. Method: A retrospective observational study was conducted among 150 malaria patients from September to December 2024 in multiple private and public hospitals in Aden, Yemen. Malaria severity was classified based on WHO criteria into severe, moderate and mild. Liver function markers, including (ALT), (AST), (T. Bilirubin), and (D. Bilirubin), were measured using spectrophotometry. Statistical analyses were performed using SPSS version 26 with significance set at p < 0.05. Results: Males (61%) were more affected than females (39%), with Plasmodium falciparum accounting for 68% of cases. Severe malaria was observed in 56% of patients. Liver enzyme levels were markedly elevated in severe malaria cases, with mean ALT at 80.29 ± 45.11 U/L and ALT at 78.46 ± 46.67 U/L. Bilirubin levels were also significantly increased (T. Bilirubin: 3.00 ± 2.3 mg/dL, D. Bilirubin: 1.19 ± 1.1 mg/dL), with a strong association between disease severity and hepatic dysfunction (p < 0.001). However, no statistical relationship was found between malaria severity and demographic characteristics, including gender (p = 0.318), place of residence (p = 0.438), and participant age (p = 0.869). Conclusion: Severe malaria is associated with significant hepatic dysfunction, characterized by elevated liver enzyme levels and hyperbilirubinemia. These findings underscore the importance of continuous liver function monitoring in malaria patients to prevent severe hepatic complications. Further research is needed to elucidate the underlying mechanisms and potential long-term impacts of malarial hepatopathy

The Bostrichidae of the Maltese Islands (Coleoptera)

The Bostrichidae of the Maltese Islands are reviewed. Ten species are recorded with certainty from this Archipelago, of which 6 namely, Trogoxylon impressum (Comolli, 1837), Amphicerus bimaculatus (A.G. Olivier, 1790), Heterobostrychus aequalis (Waterhouse, 1884), Sinoxylon unidentatum (Fabricius, 1801), Xyloperthella picea (A.G. Olivier, 1790) and Apate monachus Fabricius, 1775 are recorded for the first time. Two of the mentioned species (H. aequalis and S. unidentatum) are alien and recorded only on the basis of single captures and the possible establishment of these species is discussed. Earlier records of Scobicia pustulata (Fabricius, 1801) from Malta are incorrect and should be attributed to S. chevrieri (A. Villa & J.B. Villa, 1835). A zoogeographical analysis and an updated checklist of the 12 species of Bostrichidae recorded from the Maltese Islands and neighbouring Sicilian islands (Pantelleria, Linosa and Lampedusa) are also provided. Rhizopertha dominica (Fabricius, 1792) form granulipennis Lesne in Beeson & Bhatia, 1937 from Uttarakhand (northern India) was overlooked by almost all subsequent authors. Its history is summarized and the following new synonymy is established: Rhizopertha dominica (Fabricius, 1792) form granulipennis Lesne in Beeson & Bhatia, 1937 = Rhyzopertha dominica (Fabricius, 1792), syn. n. Finally, records of Amphicerus bimaculatus from Azerbaijan, of Bostrichus capucinus (Linnaeus, 1758) from Jordan and Syria, of Scobicia chevrieri from Jordan and Italy, of Xyloperthella picea from Italy, and of Apate monachus from Corsica (France) and Italy, are also provided.peer-reviewe

اردو ناول میں انسانی حقوق اور طبقاتی کشمکش کاشعور

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UnhideWhenUsed="false" Name="Colorful List Accent 6"/> <w:LsdException Locked="false" Priority="73" SemiHidden="false" UnhideWhenUsed="false" Name="Colorful Grid Accent 6"/> <w:LsdException Locked="false" Priority="19" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Subtle Emphasis"/> <w:LsdException Locked="false" Priority="21" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Intense Emphasis"/> <w:LsdException Locked="false" Priority="31" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Subtle Reference"/> <w:LsdException Locked="false" Priority="32" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Intense Reference"/> <w:LsdException Locked="false" Priority="33" SemiHidden="false" UnhideWhenUsed="false" QFormat="true" Name="Book Title"/> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif"; mso-fareast-font-family:"Times New Roman";} This research paper deals with the situation of human rights and class conflicts as shown in the tradition of Urdu Novel. The first part of the paper presents theoretical discussion on human rights. In the second part the works of the novelists like Nazir Ahmed, Hadi Ruswa, Prem Chand, Krishan Chander, Qurat-ul-ain Hyder, Anees Nagi, Intzar Hussain, Abdullah Hussain and Tarar have been analyzed in the light of their deep concern with the human rights and class conflict. The paper ends with the conclusion that these writers have been successful in their attempt to discuss these issues in their works.</p

دشتِ سوس کے نمائندہ کرداروں کے افکار و نظریات

Dasht-e-Soos, more sentimental and more philosophical, amazing, fascinating and astonishing dispassionate analysis of a bye gone age of Muslim history, One can imagine that the main player of Jamila Hashmi's this novel would be Hussain Bin Mansur Hillaj. However throughout the story one cannot escape the overbearing aroma of "Aghul" and other characters. This was an unexpected love story or at least with an unusual diction that one does not come across in Urdu fiction .Many of the critics expected a story that would bring out Hillaj as he was commonly imagined but Jamila Hashmi had done a lot of historical and theoretical research to write about the Sufi Saint's inner journey. Someone who challenged the Status -quo of religion in 9th century Baghdad.But Jamila Hashmi's interest was in writing about the journey which started with Aghul"and ended with every bit of Hillaj's body, as it was hung by the king's decree and then chopped into pieces , screaming Anal Haq.</p

The reality of implementing investigation activities in the science course during the application of e-learning of teacher's point of view in Najran city

هدفت هذه الدراسة إلى التعرف على واقع تنفيذ أنشطة الاستقصاء في مقررات العلوم أثناء تطبيق التعليم الإلكتروني، استخدم فيها الباحث المنهج الوصفي المسحي، وقد بلغت عينة الدراسة (73) معلماً للعلوم في المرحلة الابتدائية بمدينة نجران، في الفصل الدراسي الثاني 1442هـ، وقد توصلت هذه الدراسة إلى عدد من النتائج منها ممارسة المعلمين للاستقصاء في تنفيذ الأنشطة أثناء تطبيق التعليم الإلكتروني بدرجة استجابة أحيانا حيث بلغ المتوسط الكلي للمحور (2.30)، وتوظيف المعلمين للتقنية في تنفيذ أنشطة الاستقصاء أثناء تطبيق التعليم الإلكتروني بدرجة استجابة أحياناً حيث بلغ المتوسط الكلي للمحور (2.13)، وجود بعض المعوقات في تنفيذ أنشطة الاستقصاء أثناء تطبيق التعليم الإلكتروني حيث بلغ المتوسط الكلي للمحور (2.22)؛ كما توصلت الدراسة إلى وجود فروق ذات دلالة إحصائية في تنفيذ أنشطة الاستقصاء أثناء تطبيق التعليم الإلكتروني من وجهة نظر المعلمين تبعاً لمتغير مستوى الإلمام بالتقنية لصالح المستوى الجيد بدلالة (0.011)، كذلك وجود فروق ذات دلالة إحصائية في تنفيذ أنشطة الاستقصاء أثناء تطبيق التعليم الإلكتروني من وجهة نظر المعلمين تبعاً لمتغير تلقي الدورات التدريبية في الاستقصاء لصالح أفراد العينة الذين تلقوا الدورات التدريبية بدلالة (0.001)، وقد أوصت الدراسة بضرورة تدريب المعلمين على دمج التقنية في تنفيذ أنشطة الاستقصاء وإجراء دراسات مماثلة حول مدى استخدام المعلمين لسلم التقدير الرباعي لتقويم القدرات اللازمة لتنفيذ استقصاء علمي.This study aimed to identify the reality of the implementation of scientific investigation activities in science courses at the primary stage and during the application of e-learning، in which the researcher used a questionnaire as data collection tool after verifying its validity and reliability by applying it to an exploratory sample consisting of 20 teachers. The study sample was (73) Science teachers in the primary stage in the second semester of 1441 AH in Najran city . This study reached a number of results، including the practice of teachers to investigate the implementation of activities during the application of e-learning which sometimes have a degree of response ، where the total average of the axis reached (2.30) and teachers’ employment of technology in implementing Survey activities during the application of e-learning with a degree of response sometimes، where the total average of the axis reached (2.13) and the presence of some obstacles in the implementation of survey activities during the application of e-learning، where the total average of the axis reached (2.22). The survey during the application of e-learning from the point of view of teachers according to the variable of the level of knowledge of technology in favor of the good level with a significance (0.011) There are also statistically significant differences in the implementation of survey activities during the application of e-learning from the teachers’ point of view، according to the variable of receiving training courses in the survey in favor of the sample members who received training courses with a significance (0.001). moreover the study recommended the need to train teachers to integrate technology in the implementation of educational activities. Survey and similar studies on the extent of teachers uses of &nbsp;the Quadruple Scale to assess the capabilities needed to carry out a scientific investigatio

The Effect of Obesity on Triglycerides, Uric Acid, and Blood Pressure in People Living in Aden, Yemen. A cross-sectional Study

Obesity is a growing concern in many parts of the world, and its association with various metabolic and cardiovascular conditions has been well-documented. This study aimed to investigate the effect of obesity on triglycerides, uric acid, and blood pressure in individuals living in Aden, Yemen. A total of 100 participants were included in this study, which was conducted in June 2024 at a diagnostic lab in Aden Hospitals. The results showed that a significant percentage of participants had elevated levels of triglycerides (76%) and uric acid (54%), while over half of the participants (53%) had high blood pressure. Furthermore, there was a significant association between obesity and elevated triglyceride levels, with a p-value of less than 0.05. Other significant relationships were found between triglycerides and age, residence, as well as between uric acid and place of residence. These findings highlight the importance of addressing obesity in the context of metabolic and cardiovascular health in Aden, Yemen