Extension Military Parent–Teen Camp Experiences: Family Resilience Building in Action

The purpose of the study addressed in this article was to gather information from military service members and their teenage children attending Extension camping programs together. We used a pretest and a posttest to examine resilience of both groups and compared other postprogram youth outcome measures to a normative sample. We found statistically significant increases in resilience scores for both service member participants and teenage participants as well as elevated youth outcomes in the areas of problem solving and connecting with others. Our results constitute useful information on the value of Extension outdoor and recreational programming for family systems

Friction and Texture Equipment Correlation Study

The Kentucky Transportation Cabinet’s (KYTC) foremost goal is building and maintaining a safe road network. To accomplish this goal, KYTC needs reliable pavement friction and macrotexture data, both of which influence road performance and safety. KYTC currently measures fiction using a lock-wheel skid tester (AASHTO T 242), however, the agency has not been able to collect data at the network level due to equipment and personnel limitations. In 2020 the Cabinet commissioned a study to collect friction and macrotexture data. Investigators used a sideway-force coefficient routine investigation machine (SCRIM) (AASHTO TP 143) to measure friction. To understand the performance of a range of devices used to measure friction and macrotexture (a lock-wheel skid tester, Dynamic Friction Tester (ASTM E1011), LMI Selcom Optocator, LCMS, and AMES Laser Texture Scanner), this study evaluated the degree to which data obtained by different types of equipment are correlated. Five routes and 13 different segments were selected for the study to capture a range of friction and macrotexture values. The following surfaces were tested: concrete pavement, Superpave 0.38 bituminous pavement, crack sealed bituminous surfaces, single and double layer of microsurfacing, cape seal composed of a chip seal with microsurfacing placed on the chip seal, and a Superpave 4.75 mm bituminous surface. Friction data had seasonal corrections applied. Friction and macrotexture values obtained using different equipment types were highly correlated with one another. Due to the condition of concrete pavement and its effects on correlations and regression equations, future studies should evaluate concrete pavements and bituminous pavements separately. Only one piece of each type of equipment was used for the study. Consideration should be given to developing correlations and regression equations for each piece of equipment/device used to make measurements. Future studies should also evaluate how the seasonal factors influence correlations and regression equations

AID Project Summary Report for Intelligent Compaction

This study reviews data from five roadway construction projects on which intelligent compaction (IC) techniques were used to achieve the more uniform compaction of road-building materials. Kentucky Transportation Center (KTC) researchers looked at IC data collected from these projects — resulting in the production of eight analyzable data sets — to determine whether they complied with the special construction note included in contract documents. The report also compares the intelligent compaction measurement value (ICMV) collected on each project to traditional laboratory results. Researchers used Veta software to analyze geospatial data collected from IC machines during construction work. Of the data sets, three indicated the required minimum coverage pass count had been achieved, although these did not attain the required minimum coverage for ICMV. Three other data sets achieved minimum ICMV coverage, while the final two data sets did not reach minimum coverage for either metric. Regression analysis found no meaningful relationship between density and ICMV. Attention is also paid to challenges which arose during the review of IC data and feedback received from contractors about the use of IC. Contractors appreciate that IC is able to transmit real-time data to operators and provides access to the mat temperature, however they observed inconsistencies with the ICMV for mill/fill projects and on new construction. These inconsistencies are the product of several factors, including cuts, fills, soil types, and the amount of water in the roller. A special construction note with instructions for using IC on Federal-aid projects is included as well. It specifies materials and equipment requirements, contractor responsibilities, construction methods, payment, and performance measures

Longer Lasting Bridge Deck Overlays

The objective of this report is to determine the most effective method for bridge deck overlay construction and repair by assessing current practices; examining new products and technologies; and reviewing NCHRP (National Cooperative Highway Research Program) guidelines, state standard specifications, ASCE (American Society of Civil Engineers) infrastructure ratings, and original bridge core chloride penetration data. Based on the review, this report offers the following conclusions. Latex modified concrete (LMC) overlays perform well, provide a long service life, and are the most commonly used method of bridge deck rehabilitation. Ohio considers microsilica concrete (MSC) overlays as state of the art due to their lower permeability. Superplasticized dense concrete (SDC), fly-ash modified concrete (FAMC), and polymer modified concrete (PMC) are other acceptable choices for bridge deck overlays. Silane or epoxy sealers may be used as a low-cost preventative approach to slow the deterioration of concrete bridge decks. Waterproofing membranes have produced mixed results but have the potential to be an effective system if installed correctly. Rosphalt® can be an expensive material but offers benefits such as minimizing traffic disruption due to shorter installation periods and increased durability. The two most important conclusions drawn from this research are the importance of a comprehensive approach when selecting a bridge deck rehabilitation method, and the importance of properly following instructions when installing overlays or waterproofing membrane systems

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

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Yorkshire Enhanced Stop Smoking study (YESS): a protocol for a randomised controlled trial to evaluate the effect of adding a personalised smoking cessation intervention to a lung cancer screening programme

Introduction:Integration of smoking cessation (SC) into lung cancer screening (LCS) is essential to optimise clinical and cost effectiveness. The most effective way to use this “teachable moment” is unclear. The Yorkshire Enhanced Stop Smoking study (YESS) will measure the effectiveness of a SC service integrated within the Yorkshire Lung Screening Trial (YLST) and will test the efficacy of a personalised SC intervention, incorporating incidental findings detected on the low-dose computed tomography scan performed as part of YLST.Methods and analysis: Unless explicitly declined, all smokers enrolled in YLST will see a Smoking Cessation Practitioner (SCP) at baseline and receive smoking cessation support over 4-weeks comprising behavioural support, pharmacotherapy and/or a commercially available e-cigarette. Eligible smokers will be randomised (1:1 in permuted blocks of random size up to size 6) to receive either an enhanced, personalised smoking cessation support package, including CT scan images, or continued SBP. Anticipated recruitment is 1040 smokers (January 2019 – December 2020). The primary objective is to measure 7-day point prevalent carbon monoxide (CO) validated smoking cessation after 3-months. Secondary outcomes include CO validated cessation at 4-weeks and 12-months, self-reported continuous cessation at 4-weeks, 3-month and 12-months, attempts to quit smoking and changes in psychological variables, including perceived risk of lung cancer, motivation to quit smoking tobacco, confidence and efficacy beliefs (self and response) at all follow up points. A process evaluation will explore under which circumstances and on which groups the intervention works best, test intervention fidelity and theory test the mechanisms of intervention impact.Ethics and dissemination: This study has been approved by the East Midlands-Derby Research Ethics Committee (18/EM/0199) and the Health Research Authority/Health and Care Research Wales. Results will be disseminated through publication in peer-reviewed scientific journals, presentation at conferences and via the YLST website. Trial registration number: ISRCTN63825779; NIH ClinicalTrials.gov NCT0375011

High fidelity frictional models for MEMS.

The primary goals of the present study are to: (1) determine how and why MEMS-scale friction differs from friction on the macro-scale, and (2) to begin to develop a capability to perform finite element simulations of MEMS materials and components that accurately predicts response in the presence of adhesion and friction. Regarding the first goal, a newly developed nanotractor actuator was used to measure friction between molecular monolayer-coated, polysilicon surfaces. Amontons law does indeed apply over a wide range of forces. However, at low loads, which are of relevance to MEMS, there is an important adhesive contribution to the normal load that cannot be neglected. More importantly, we found that at short sliding distances, the concept of a coefficient of friction is not relevant; rather, one must invoke the notion of 'pre-sliding tangential deflections' (PSTD). Results of a simple 2-D model suggests that PSTD is a cascade of small-scale slips with a roughly constant number of contacts equilibrating the applied normal load. Regarding the second goal, an Adhesion Model and a Junction Model have been implemented in PRESTO, Sandia's transient dynamics, finite element code to enable asperity-level simulations. The Junction Model includes a tangential shear traction that opposes the relative tangential motion of contacting surfaces. An atomic force microscope (AFM)-based method was used to measure nano-scale, single asperity friction forces as a function of normal force. This data is used to determine Junction Model parameters. An illustrative simulation demonstrates the use of the Junction Model in conjunction with a mesh generated directly from an atomic force microscope (AFM) image to directly predict frictional response of a sliding asperity. Also with regards to the second goal, grid-level, homogenized models were studied. One would like to perform a finite element analysis of a MEMS component assuming nominally flat surfaces and to include the effect of roughness in such an analysis by using a homogenized contact and friction models. AFM measurements were made to determine statistical information on polysilicon surfaces with different roughnesses, and this data was used as input to a homogenized, multi-asperity contact model (the classical Greenwood and Williamson model). Extensions of the Greenwood and Williamson model are also discussed: one incorporates the effect of adhesion while the other modifies the theory so that it applies to the case of relatively few contacting asperities

Haematological consequences of acute uncomplicated falciparum malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data

Background: Plasmodium falciparum malaria is associated with anaemia-related morbidity, attributable to host, parasite and drug factors. We quantified the haematological response following treatment of uncomplicated P. falciparum malaria to identify the factors associated with malarial anaemia. Methods: Individual patient data from eligible antimalarial efficacy studies of uncomplicated P. falciparum malaria, available through the WorldWide Antimalarial Resistance Network data repository prior to August 2015, were pooled using standardised methodology. The haematological response over time was quantified using a multivariable linear mixed effects model with nonlinear terms for time, and the model was then used to estimate the mean haemoglobin at day of nadir and day 7. Multivariable logistic regression quantified risk factors for moderately severe anaemia (haemoglobin &lt; 7 g/dL) at day 0, day 3 and day 7 as well as a fractional fall ≥ 25% at day 3 and day 7. Results: A total of 70,226 patients, recruited into 200 studies between 1991 and 2013, were included in the analysis: 50,859 (72.4%) enrolled in Africa, 18,451 (26.3%) in Asia and 916 (1.3%) in South America. The median haemoglobin concentration at presentation was 9.9 g/dL (range 5.0–19.7 g/dL) in Africa, 11.6 g/dL (range 5.0–20.0 g/dL) in Asia and 12.3 g/dL (range 6.9–17.9 g/dL) in South America. Moderately severe anaemia (Hb &lt; 7g/dl) was present in 8.4% (4284/50,859) of patients from Africa, 3.3% (606/18,451) from Asia and 0.1% (1/916) from South America. The nadir haemoglobin occurred on day 2 post treatment with a mean fall from baseline of 0.57 g/dL in Africa and 1.13 g/dL in Asia. Independent risk factors for moderately severe anaemia on day 7, in both Africa and Asia, included moderately severe anaemia at baseline (adjusted odds ratio (AOR) = 16.10 and AOR = 23.00, respectively), young age (age &lt; 1 compared to ≥ 12 years AOR = 12.81 and AOR = 6.79, respectively), high parasitaemia (AOR = 1.78 and AOR = 1.58, respectively) and delayed parasite clearance (AOR = 2.44 and AOR = 2.59, respectively). In Asia, patients treated with an artemisinin-based regimen were at significantly greater risk of moderately severe anaemia on day 7 compared to those treated with a non-artemisinin-based regimen (AOR = 2.06 [95%CI 1.39–3.05], p &lt; 0.001). Conclusions: In patients with uncomplicated P. falciparum malaria, the nadir haemoglobin occurs 2 days after starting treatment. Although artemisinin-based treatments increase the rate of parasite clearance, in Asia they are associated with a greater risk of anaemia during recovery.</p

Yorkshire Enhanced Stop Smoking (YESS) study: a protocol for a randomised controlled trial to evaluate the effect of adding a personalised smoking cessation intervention to a lung cancer screening programme

Introduction:Integration of smoking cessation (SC) into lung cancer screening (LCS) is essential to optimise clinical and cost effectiveness. The most effective way to use this “teachable moment” is unclear. The Yorkshire Enhanced Stop Smoking study (YESS) will measure the effectiveness of a SC service integrated within the Yorkshire Lung Screening Trial (YLST) and will test the efficacy of a personalised SC intervention, incorporating incidental findings detected on the low-dose computed tomography scan performed as part of YLST.Methods and analysis: Unless explicitly declined, all smokers enrolled in YLST will see a Smoking Cessation Practitioner (SCP) at baseline and receive smoking cessation support over 4-weeks comprising behavioural support, pharmacotherapy and/or a commercially available e-cigarette. Eligible smokers will be randomised (1:1 in permuted blocks of random size up to size 6) to receive either an enhanced, personalised smoking cessation support package, including CT scan images, or continued SBP. Anticipated recruitment is 1040 smokers (January 2019 – December 2020). The primary objective is to measure 7-day point prevalent carbon monoxide (CO) validated smoking cessation after 3-months. Secondary outcomes include CO validated cessation at 4-weeks and 12-months, self-reported continuous cessation at 4-weeks, 3-month and 12-months, attempts to quit smoking and changes in psychological variables, including perceived risk of lung cancer, motivation to quit smoking tobacco, confidence and efficacy beliefs (self and response) at all follow up points. A process evaluation will explore under which circumstances and on which groups the intervention works best, test intervention fidelity and theory test the mechanisms of intervention impact.Ethics and dissemination: This study has been approved by the East Midlands-Derby Research Ethics Committee (18/EM/0199) and the Health Research Authority/Health and Care Research Wales. Results will be disseminated through publication in peer-reviewed scientific journals, presentation at conferences and via the YLST website. Trial registration number: ISRCTN63825779; NIH ClinicalTrials.gov NCT0375011