1,570 research outputs found
Fluid Dynamic Effects of Ring- Type Internals in a Dual Circulating Fluidized Bed System
Intensified gas-solids contact in the fuel reactor of chemical looping combustion systems can be a key issue for achieving the necessary gas-phase conversion rates. Wedge-shaped rings were designed and installed in the fuel reactor of a cold flow model for fluid dynamic testing. These internals are meant to reduce the typical radial and axial solids concentration non-uniformity. It is shown, that more solids are present in the upper regions of the riser when in-ternals are used. Additionally, increase of the solids elutriation rate from the riser was foun
Synthesis of a 12R-type hexagonal perovskite solid solution Sr3NdNb3-xTixO12-delta and the influence of acceptor doping on electrical properties
A solid solution forms for Sr3NdNb3âxTixO12âÎŽ with approximate limits 0 †x †0.06. The system crystallizes with a 12R-type hexagonal perovskite structure in the space group R[3 with combining macron], as determined by neutron diffraction and selected area electron diffraction. The electrical properties of the end members have been investigated by impedance spectroscopy in the temperature range 550â800 °C under various gas atmospheres and as a function of oxygen and water-vapour partial pressure. Proton transport dominates under wet oxidising conditions in the temperature range 550â700 °C, as confirmed by the H+/D+ isotope effect. Acceptor doping considerably enhances proton conductivity with a value of 3.3 Ă 10â6 S cmâ1 for the bulk response of x = 0.06 at 700 °C in moistened air. The presence of a âÂŒ slope for both doped and undoped samples in the range 10â19 †pO2 †10â8 atm at 900 °C indicates n-type transport under reducing conditions following the extrinsic model attributable to acceptor centres. The conductivity is essentially independent of pO2 at 600 °C under dry oxidising conditions, consistent with oxide-ion transport; a positive power-law dependence at higher temperature indicates extrinsic behaviour and a significant electronâhole contribution. The dielectric constant at RT of nominally stoichiometric Sr3NdNb3O12 is Δr ⌠37, with a moderately high quality factor of Q Ă f ⌠16 400 GHz at fr ⌠6.4 GHz. The temperature coefficient of resonant frequency of x = 0 is Ïf ⌠12 ppm °Câ1, which lowers to â3 ppm °Câ1 for the Ti-doped phase x = 0.06
Tomonaga-Luttinger features in the resonant Raman spectra of quantum wires
The differential cross section for resonant Raman scattering from the
collective modes in a one dimensional system of interacting electrons is
calculated non-perturbatively using the bosonization method. The results
indicate that resonant Raman spectroscopy is a powerful tool for studying
Tomonaga-Luttinger liquid behaviour in quasi-one dimensional electron systems.Comment: 4 pages, no figur
Letter to the Editor: "Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline"
We read with interest the recently published clinical practice guidelines for preventing and treating childhood obesity (1). The authors reported their evaluation of the quality of the evidence and an assessment of the strength of recommendations according to objective criteria across a diverse literature. In our view, however, this excellent and comprehensive report does not mention two relevant issues: attrition and enrollment. These issues are likely to be of concern for clinicians, administrators, and researchers because they can have a substantial impact on clinical care
Lymphovascular and perineural invasion as selection criteria for adjuvant therapy in intrahepatic cholangiocarcinoma: a multi-institution analysis
AbstractObjectivesCriteria for the selection of patients for adjuvant chemotherapy in intrahepatic cholangiocarcinoma (IHCC) are lacking. Some authors advocate treating patients with lymph node (LN) involvement; however, nodal assessment is often inadequate or not performed. This study aimed to identify surrogate criteria based on characteristics of the primary tumour.MethodsA total of 58 patients who underwent resection for IHCC between January 2000 and January 2010 at any of three institutions were identified. Primary outcome was overall survival (OS).ResultsMedian OS was 23.0months. Median tumour size was 6.5cm and the median number of lesions was one. Overall, 16% of patients had positive margins, 38% had perineural invasion (PNI), 40% had lymphovascular invasion (LVI) and 22% had LN involvement. A median of two LNs were removed and a median of zero were positive. Lymph nodes were not sampled in 34% of patients. Lymphovascular and perineural invasion were associated with reduced OS [9.6months vs. 32.7months (P= 0.020) and 10.7months vs. 32.7months (P= 0.008), respectively]. Lymph node involvement indicated a trend towards reduced OS (10.7months vs. 30.0months; P= 0.063). The presence of either LVI or PNI in node-negative patients was associated with a reduction in OS similar to that in node-positive patients (12.1months vs. 10.7months; P= 0.541). After accounting for adverse tumour factors, only LVI and PNI remained associated with decreased OS on multivariate analysis (hazard ratio4.07, 95% confidence interval 1.60â10.40; P= 0.003).ConclusionsLymphovascular and perineural invasion are separately associated with a reduction in OS similar to that in patients with LN-positive disease. As nodal dissection is often not performed and the number of nodes retrieved is frequently inadequate, these tumour-specific factors should be considered as criteria for selection for adjuvant chemotherapy
Prescription Opioid Use Among Hispanics/Latinos With Arthritis Symptoms: Results From the Hispanic Community Health Study/Study of Latinos
Introduction: To determine the prevalence of prescription opioid (PO) use among Hispanics/Latinos with arthritis symptoms and to characterize how demographic and cultural factors are associated with PO use. Method: Cross-sectional analysis of baseline visit data during 2008 to 2011 from the Hispanic Community Health Study/Study of Latinos, a population-based cohort study of 16,415 Hispanics/Latinos living in Chicago, Illinois, Miami, Florida, Bronx, New York, and San Diego, California. Included participants self-reported painful inflammation or swelling in one or more joints. Multivariate models controlling for physical and mental health scores were constructed to assess how demographic and cultural factors were associated with PO use. Results: A total of 9.3% were using POs at the time of the baseline visit. In multivariate models, persons of Cuban background (adjusted odds ratio [AOR] = 0.42, 95% confidence interval [CI; 0.21, 0.81]) and of Dominican background (AOR = 0.38, 95% CI [0.18, 0.80]) were significantly less likely to use POs compared with a reference group of persons of Mexican background. Greater language acculturation was also negatively associated with PO use (AOR = 0.68, 95% CI [0.53, 0.87]). Conclusion: POs were used relatively uncommonly, and use showed marked variation between Hispanic/Latino groups. Future study should determine mechanisms for why greater use of English among Hispanics/Latinos might influence PO use
Visual fixation and continuous head rotations have minimal effect on set-point adaptation to magnetic vestibular stimulation
Background: Strong static magnetic fields such as those in an MRI machine can induce sensations of self-motion and nystagmus. The proposed mechanism is a Lorentz force resulting from the interaction between strong static magnetic fields and ionic currents in the inner ear endolymph that causes displacement of the semicircular canal cupulae. Nystagmus persists throughout an individual's exposure to the magnetic field, though its slow-phase velocity partially declines due to adaptation. After leaving the magnetic field an after effect occurs in which the nystagmus and sensations of rotation reverse direction, reflecting the adaptation that occurred while inside the MRI. However, the effects of visual fixation and of head shaking on this early type of vestibular adaptation are unknown. Methods: Three-dimensional infrared video-oculography was performed in six individuals just before, during (5, 20, or 60 min) and after (4, 15, or 20 min) lying supine inside a 7T MRI scanner. Trials began by entering the magnetic field in darkness followed 60 s later, either by light with visual fixation and head still, or by continuous yaw head rotations (2 Hz) in either darkness or light with visual fixation. Subjects were always placed in darkness 10 or 30 s before exiting the bore. In control conditions subjects remained in the dark with the head still for the entire duration. Results: In darkness with head still all subjects developed horizontal nystagmus inside the magnetic field, with slow-phase velocity partially decreasing over time. An after effect followed on exiting the magnet, with nystagmus in the opposite direction. Nystagmus was suppressed during visual fixation; however, after resuming darkness just before exiting the magnet, nystagmus returned with velocity close to the control condition and with a comparable after effect. Similar after effects occurred with continuous yaw head rotations while in the scanner whether in darkness or light. Conclusions: Visual fixation and sustained head shaking either in the dark or with fixation inside a strong static magnetic field have minimal impact on the short-term mechanisms that attempt to null unwanted spontaneous nystagmus when the head is still, so called VOR set-point adaptation. This contrasts with the critical influence of vision and slippage of images on the retina on the dynamic (gain and direction) components of VOR adaptation
Circumstellar interaction in supernovae in dense environments - an observational perspective
In a supernova explosion, the ejecta interacting with the surrounding
circumstellar medium (CSM) give rise to variety of radiation. Since CSM is
created from the mass lost from the progenitor star, it carries footprints of
the late time evolution of the star. This is one of the unique ways to get a
handle on the nature of the progenitor star system. Here, I will focus mainly
on the supernovae (SNe) exploding in dense environments, a.k.a. Type IIn SNe.
Radio and X-ray emission from this class of SNe have revealed important
modifications in their radiation properties, due to the presence of high
density CSM. Forward shock dominance of the X-ray emission, internal free-free
absorption of the radio emission, episodic or non-steady mass loss rate,
asymmetry in the explosion seem to be common properties of this class of SNe.Comment: Fixed minor typos. 31 pages, 9 figures, accepted for publication in
Space Science Reviews. Chapter in International Space Science Institute
(ISSI) Book on "Supernovae" to be published in Space Science Reviews by
Springe
Adsorption of mono- and multivalent cat- and anions on DNA molecules
Adsorption of monovalent and multivalent cat- and anions on a deoxyribose
nucleic acid (DNA) molecule from a salt solution is investigated by computer
simulation. The ions are modelled as charged hard spheres, the DNA molecule as
a point charge pattern following the double-helical phosphate strands. The
geometrical shape of the DNA molecules is modelled on different levels ranging
from a simple cylindrical shape to structured models which include the major
and minor grooves between the phosphate strands. The densities of the ions
adsorbed on the phosphate strands, in the major and in the minor grooves are
calculated. First, we find that the adsorption pattern on the DNA surface
depends strongly on its geometrical shape: counterions adsorb preferentially
along the phosphate strands for a cylindrical model shape, but in the minor
groove for a geometrically structured model. Second, we find that an addition
of monovalent salt ions results in an increase of the charge density in the
minor groove while the total charge density of ions adsorbed in the major
groove stays unchanged. The adsorbed ion densities are highly structured along
the minor groove while they are almost smeared along the major groove.
Furthermore, for a fixed amount of added salt, the major groove cationic charge
is independent on the counterion valency. For increasing salt concentration the
major groove is neutralized while the total charge adsorbed in the minor groove
is constant. DNA overcharging is detected for multivalent salt. Simulations for
a larger ion radii, which mimic the effect of the ion hydration, indicate an
increased adsorbtion of cations in the major groove.Comment: 34 pages with 14 figure
Improved constraints on the expansion rate of the Universe up to z~1.1 from the spectroscopic evolution of cosmic chronometers
We present new improved constraints on the Hubble parameter H(z) in the
redshift range 0.15 < z < 1.1, obtained from the differential spectroscopic
evolution of early-type galaxies as a function of redshift. We extract a large
sample of early-type galaxies (\sim11000) from several spectroscopic surveys,
spanning almost 8 billion years of cosmic lookback time (0.15 < z < 1.42). We
select the most massive, red elliptical galaxies, passively evolving and
without signature of ongoing star formation. Those galaxies can be used as
standard cosmic chronometers, as firstly proposed by Jimenez & Loeb (2002),
whose differential age evolution as a function of cosmic time directly probes
H(z). We analyze the 4000 {\AA} break (D4000) as a function of redshift, use
stellar population synthesis models to theoretically calibrate the dependence
of the differential age evolution on the differential D4000, and estimate the
Hubble parameter taking into account both statistical and systematical errors.
We provide 8 new measurements of H(z) (see Tab. 4), and determine its change in
H(z) to a precision of 5-12% mapping homogeneously the redshift range up to z
\sim 1.1; for the first time, we place a constraint on H(z) at z \neq 0 with a
precision comparable with the one achieved for the Hubble constant (about 5-6%
at z \sim 0.2), and covered a redshift range (0.5 < z < 0.8) which is crucial
to distinguish many different quintessence cosmologies. These measurements have
been tested to best match a \Lambda CDM model, clearly providing a
statistically robust indication that the Universe is undergoing an accelerated
expansion. This method shows the potentiality to open a new avenue in constrain
a variety of alternative cosmologies, especially when future surveys (e.g.
Euclid) will open the possibility to extend it up to z \sim 2.Comment: 34 pages, 15 figures, 6 tables, published in JCAP. It is a companion
to Moresco et al. (2012b, http://arxiv.org/abs/1201.6658) and Jimenez et al.
(2012, http://arxiv.org/abs/1201.3608). The H(z) data can be downloaded at
http://www.physics-astronomy.unibo.it/en/research/areas/astrophysics/cosmology-with-cosmic-chronometer
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