551 research outputs found

    Recognising the Key Role of Agriculture In Achieving Sustainable Development Goal 2: Challenges And Prospects In Nigeria

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    The issue of food security has in recent times attracted a lot of scholarly debates in Nigeria. In spite of different methodologies utilised by the governments in addressing the challenge, the issue still persists. Results further revealed that the agricultural sector has not performed palatably in its quest for ensuring sustainable development. Suffice to note that agriculture should be given its rightful place if the country wants to experience development that will be said to be sustainable. In addressing this, the second Sustainable Development Goals (SDGs) become handy because of its emphasis on eradicating hunger, which can only be achieved when the role of agriculture is recognised in the nation. It is on this premise that this paper examined the key role of Agriculture in achieving Sustainable Development Goal 2 in Nigeria. This is a conceptual paper that relies on an extensive review of related literature. The findings show that the agriculture sector faces many challenges, making it quite difficult in achieving its main goal which is ensuring an adequate supply of food in all parts of the country. In specificterms, the current insurgency in Northern Nigeria has been one of the major factors which have further destabilised the lopsided agricultural sector in the country. The paper recommended among others that investment in the agricultural sector should be given top priority by the Federal, State and Local Governments so that the continuous dependence on imported products will be reduced, as well as to relieve dependence on the oil sector for economic growth

    Beyond Prejudice as Simple Antipathy: Hostile and Benevolent Sexism Across Cultures

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    The authors argue that complementary hostile and benevolent componen:s of sexism exist ac ro.ss cultures. Male dominance creates hostile sexism (HS). but men's dependence on women fosters benevolent sexism (BS)-subjectively positive attitudes that put women on a pedestal but reinforce their subordination. Research with 15,000 men and women in 19 nations showed that (a) HS and BS are coherenl constructs th at correlate positively across nations, but (b) HS predicts the ascription of negative and BS the ascription of positive traits to women, (c) relative to men, women are more likely to reject HS than BS. especially when overall levels of sexism in a culture are high, and (d) national averages on BS and HS predict gender inequal ity across nations. These results challenge prevailing notions of prejudice as an antipathy in that BS (an affectionate, patronizing ideology) reflects inequality and is a cross-culturally pervasive complement to HS

    Costs and Cost-Effectiveness of Hypertension Screening and Treatment in Adults with Hypertension in Rural Nigeria in the Context of a Health Insurance Program.

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    BACKGROUND: High blood pressure is a leading risk factor for death and disability in sub-Saharan Africa (SSA). We evaluated the costs and cost-effectiveness of hypertension care provided within the Kwara State Health Insurance (KSHI) program in rural Nigeria. METHODS: A Markov model was developed to assess the costs and cost-effectiveness of population-level hypertension screening and subsequent antihypertensive treatment for the population at-risk of cardiovascular disease (CVD) within the KSHI program. The primary outcome was the incremental cost per disability-adjusted life year (DALY) averted in the KSHI scenario compared to no access to hypertension care. We used setting-specific and empirically-collected data to inform the model. We defined two strategies to assess eligibility for antihypertensive treatment based on 1) presence of hypertension grade 1 and 10-year CVD risk of >20%, or grade 2 hypertension irrespective of 10-year CVD risk (hypertension and risk based strategy) and 2) presence of hypertension in combination with a CVD risk of >20% (risk based strategy). We generated 95% confidence intervals around the primary outcome through probabilistic sensitivity analysis. We conducted one-way sensitivity analyses across key model parameters and assessed the sensitivity of our results to the performance of the reference scenario. RESULTS: Screening and treatment for hypertension was potentially cost-effective but the results were sensitive to changes in underlying assumptions with a wide range of uncertainty. The incremental cost-effectiveness ratio for the first and second strategy respectively ranged from US1,406toUS 1,406 to US 7,815 and US732toUS 732 to US 2,959 per DALY averted, depending on the assumptions on risk reduction after treatment and compared to no access to antihypertensive treatment. CONCLUSIONS: Hypertension care within a subsidized private health insurance program may be cost-effective in rural Nigeria and public-private partnerships such as the KSHI program may provide opportunities to finance CVD prevention care in SSA

    Survivorship patterns of histopathological variants and molecular subtypes of breast cancer in a teaching hospital in Nigeria

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    Objective: To study the relationship of histopathological characteristics, molecular subtypes of breast cancer and survival in a low resource setting.Design: Tumours from prospectively ascertained patients newly diagnosed with breast cancer were analyzed. Formalin-fixed and paraffin-embedded sections were constructed into tissue micro-arrays and immunostained with five anti-bodies. Five molecular subtypes were determined.Settings: The study was conducted jointly in the Department of Pathology of University of Ilorin Teaching Hospital, Ilorin in Nigeria and at the University of Chicago in the United States.Subjects: The study included a total of 203 histologically confirmed breast cancer patients whose pathological specimens were processed in the Department of Pathology of University of Ilorin Teaching Hospital, Ilorin, Nigeria between January 2003 and December 2007.Results: Mean age at diagnosis was 49.2 (SO ±11.9) years. Median time from symptom onset to cancer diagnosis was six months. Median follow-up time was 8.3 months. Median tumour size at diagnosis was 6cm. The proportion of ER+, PR+, HER2+ tumours were 27%, 16% and 30%, respectively. The most common molecular subtype was basal-like (25.1%) followed by unclassified (24.0%), luminal A (20.5%), HER2+/ER( 19.3%) and luminal B (11.1 %). Luminal A and B had best prognosis while basal-like and unclassified had worst prognosis. ER+ patients had longer duration of symptoms to diagnosis (median 8 months) than ER- patients (5 months) but ER+ patients had smaller tumours (median 5cm) than ER-patients (6cm, p=0.02). Recurrence-free survival was best for stage 1 and worst for stage 4 tumours. About 32.6% of patients had locoregional and/or metastatic recurrence.Conclusions: In consecutive breast cancer cases in Nigeria, almost half of patients were triple negative. Luminal A and B subtypes had best prognosis while triple negative had worst prognosis. The delay in breast cancer diagnosis and higher proportion of late stage of breast cancer underscores need for prompt diagnosis and initiation of treatment, especially hormonal therapy for ER positive patients

    Some open questions in TDDFT: Clues from Lattice Models and Kadanoff-Baym Dynamics

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    Two aspects of TDDFT, the linear response approach and the adiabatic local density approximation, are examined from the perspective of lattice models. To this end, we review the DFT formulations on the lattice and give a concise presentation of the time-dependent Kadanoff-Baym equations, used to asses the limitations of the adiabatic approximation in TDDFT. We present results for the density response function of the 3D homogeneous Hubbard model, and point out a drawback of the linear response scheme based on the linearized Sham-Schl\"uter equation. We then suggest a prescription on how to amend it. Finally, we analyze the time evolution of the density in a small cubic cluster, and compare exact, adiabatic-TDDFT and Kadanoff-Baym-Equations densities. Our results show that non-perturbative (in the interaction) adiabatic potentials can perform quite well for slow perturbations but that, for faster external fields, memory effects, as already present in simple many-body approximations, are clearly required.Comment: 15 pages, submitted to Chemical Physic

    Quality Attributes of Heat Treated Cocoyam (Colocasia esculenta) Flour

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    Cocoyam (Colocasia esculenta), a staple food and a food thickner has a small starch grains and improved digestibility. In view of adding value to cocoyam, this study investigated the effect of different processing methods on the quality of cocoyam flour. In this study, cocoyam samples were given different heat treatments and milled into flour. The moisture content of the flour samples ranged between 7.85% - 18.75%. Protein content was between 3.48% - 12.60%. Loose bulk density ranged between 0.77g/cm3 – 0.83g/cm3 initially and 0.45g/cm3 – 0.56g/cm3 finally. Starch content ranged from 16.06% - 52.84%. The control sample that has no heat treatment has the highest value of overall acceptability. Keywords : Cocoyam, digestibility, heat treatment and value additio

    The Financial Burden of Non-Communicable Chronic Diseases in Rural Nigeria: Wealth and Gender Heterogeneity in Health Care Utilization and Health Expenditures

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    Objectives Better insights into health care utilization and out-of-pocket expenditures for non-communicable chronic diseases (NCCD) are needed to develop accessible health care and limit the increasing financial burden of NCCDs in Sub-Saharan Africa. Methods A household survey was conducted in rural Kwara State, Nigeria, among 5,761 individuals. Data were obtained using biomedical and socio-economic questionnaires. Health care utilization, NCCD-related health expenditures and distances to health care providers were compared by sex and by wealth quintile, and a Heckman regression model was used to estimate health expenditures taking selection bias in health care utilization into account. Results The prevalence of NCCDs in our sample was 6.2%. NCCD-affected individuals from the wealthiest quintile utilized formal health care nearly twice as often as those from the lowest quintile (87.8% vs 46.2%, p = 0.002). Women reported foregone formal care more often than men (43.5% vs. 27.0%, p = 0.058). Health expenditures relative to annual consumption of the poorest quintile exceeded those of the highest quintile 2.2-fold, and the poorest quintile exhibited a higher rate of catastrophic health spending (10.8% among NCCD-affected households) than the three upper quintiles (4.2% to 6.7%). Long travel distances to the nearest provider, highest for the poorest quintile, were a significant deterrent to seeking care. Using distance to the nearest facility as instrument to account for selection into health care utilization, we estimated out-of-pocket health care expenditures for NCCDs to be significantly higher in the lowest wealth quintile compared to the three upper quintiles. Conclusions Facing potentially high health care costs and poor accessibility of health care facilities, many individuals suffering from NCCDs—particularly women and the poor—forego formal care, thereby increasing the risk of more severe illness in the future. When seeking care, the poor spend less on treatment than the rich, suggestive of lower quality care, while their expenditures represent a higher share of their annual household consumption. This calls for targeted interventions that enhance health care accessibility and provide financial protection from the consequences of NCCDs, especially for vulnerable populations

    Impact of Chlamydia trachomatis in the reproductive setting: British Fertility Society Guidelines for practice

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    Chlamydia trachomatis infection of the genital tract is the most common sexually transmitted infection and has a world-wide distribution. The consequences of infection have an adverse effect on the reproductive health of women and are a common cause of infertility. Recent evidence also suggests an adverse effect on male reproduction. There is a need to standardise the approach in managing the impact of C. trachomatis infection on reproductive health. We have surveyed current UK practice towards screening and management of Chlamydia infections in the fertility setting. We found that at least 90% of clinicians surveyed offered screening. The literature on this topic was examined and revealed a paucity of solid evidence for estimating the risks of long-term reproductive sequelae following lower genital tract infection with C. trachomatis. The mechanism for the damage that occurs after Chlamydial infections is uncertain. However, instrumentation of the uterus in women with C. trachomatis infection is associated with a high risk of pelvic inflammatory disease, which can be prevented by appropriate antibiotic treatment and may prevent infected women from being at increased risk of the adverse sequelae, such as ectopic pregnancy and tubal factor infertility. Recommendations for practice have been proposed and the need for further studies is identified

    Design, fabrication and evaluation of fish meal pelletizing machine

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    A 113.1kg/h fish meal pellet processing machine which produced 4mm diameter pellet, with an average length of 6mm was designed and fabricated. Design values of 210 was used for the maximum angle that the hopper wall formed with the vertical in the discharge zone, a critical stress of 1.3kPa of the ground particulate materials, and a density of 2.4521kg/m3 of the particulate materials, were used to obtain a hopper smallest outlet diameter of 12.7cm with a capacity of 24,118cm3 which proved efficient for the pelletizing machine. Two 3-cm diameter shafts carried the speed reduction gears with the perforated disc attached to the roller cutters on one end, while at the other end a 5hp motor was connected to the speed reduction gear by pulleys with diameters of 6cm and 12cm respectively. The speed reduction was 1:5 over a motor speed of 2000rpm. The fish meal pelletizing machine utilized 4kg of ingredients to produce 3.77kg pellets at an efficiency of 94.2%. The percentage loss due to unprocessed ground particulate materials was 5.8%.The moisture content of the fish meal pellets after 7days of drying in open air was 26.5% (wet basis). When tested for floatation, the pellets stayed afloat for 9 days, while the un-dried pellets only remained afloat for 2days. A combination of the weight of the twin roller cutters and the addition of some starch to the ground particulate materials assisted the compacting and gelatinization of pellet formed. This machine will be useful to medium and small scale aquaculture farmers and also reduce the need for foreign sources of fish meal in the aquaculture industry, thus conserving foreign exchange.Keywords: Ground particulate materials; mixing; compacting; gelatinizing; pelletizin
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