Infrared cutoffs and the adiabatic limit in noncommutative spacetime

We discuss appropriate infrared cutoffs and their adiabatic limit for field theories on the noncommutative Minkowski space in the Yang-Feldman formalism. In order to do this, we consider a mass term as interaction term. We show that an infrared cutoff can be defined quite analogously to the commutative case and that the adiabatic limit of the two-point function exists and coincides with the expectation, to all orders.Comment: 19 page

The wave front set of oscillatory integrals with inhomogeneous phase function

A generalized notion of oscillatory integrals that allows for inhomogeneous phase functions of arbitrary positive order is introduced. The wave front set of the resulting distributions is characterized in a way that generalizes the well-known result for phase functions that are homogeneous of order one.Comment: 12 pages, published versio

On the increased climate sensitivity in the EC-Earth model from CMIP5 to CMIP6

Many modelling groups that contribute to CMIP6 (Coupled Model Intercomparison Project Phase 6) have found a larger equilibrium climate sensitivity (ECS) with their latest model versions compared with the values obtained with the earlier versions used in CMIP5. This is also the case for the EC-Earth model. Therefore, in this study, we investigate what developments since the CMIP5 era could have caused the increase in the ECS in this model. Apart from increases in the horizontal and vertical resolution, the EC-Earth model has also substantially changed the representation of aerosols; in particular, it has introduced a more sophisticated description of aerosol indirect effects. After testing the model with some of the recent updates switched off, we find that the ECS increase can be attributed to the more advanced treatment of aerosols, with the largest contribution coming from the effect of aerosols on cloud microphysics (cloud lifetime or second indirect effect). The increase in climate sensitivity is unrelated to model tuning, as all experiments were performed with the same tuning parameters and only the representation of the aerosol effects was changed. These results cannot be generalised to other models, as their CMIP5 and CMIP6 versions may differ with respect to aspects other than the aerosol-cloud interaction, but the results highlight the strong sensitivity of ECS to the details of the aerosol forcing

The quiet crossing of ocean tipping points

Anthropogenic climate change profoundly alters the ocean’s environmental conditions, which, in turn, impact marine ecosystems. Some of these changes are happening fast and may be difficult to reverse. The identification and monitoring of such changes, which also includes tipping points, is an ongoing and emerging research effort. Prevention of negative impacts requires mitigation efforts based on feasible research-based pathways. Climate-induced tipping points are traditionally associated with singular catastrophic events (relative to natural variations) of dramatic negative impact. High-probability high-impact ocean tipping points due to warming, ocean acidification, and deoxygenation may be more fragmented both regionally and in time but add up to global dimensions. These tipping points in combination with gradual changes need to be addressed as seriously as singular catastrophic events in order to prevent the cumulative and often compounding negative societal and Earth system impacts

Density functional theory study of the multimode Jahn-Teller effect – ground state distortion of benzene cation

The multideterminental-DFT approach performed to analyze Jahn-Teller (JT) active molecules is described. Extension of this method for the analysis of the adiabatic potential energy surfaces and the multimode JT effect is presented. Conceptually a simple model, based on the analogy between the JT distortion and reaction coordinates gives further information about microscopic origin of the JT effect. Within the harmonic approximation the JT distortion can be expressed as a linear combination of all totally symmetric normal modes in the low symmetry minimum energy conformation, which allows calculating the Intrinsic Distortion Path, IDP, exactly from the high symmetry nuclear configuration to the low symmetry energy minimum. It is possible to quantify the contribution of different normal modes to the distortion, their energy contribution to the total stabilization energy and how their contribution changes along the IDP. It is noteworthy that the results obtained by both multideterminental-DFT and IDP methods for different classes of JT active molecules are consistent and in agreement with available theoretical and experimental values. As an example, detailed description of the ground state distortion of benzene cation is given

Volume, heat, and freshwater transports of the global ocean circulation 1993-2000, estimated from a general circulation model constrained by World Ocean Circulation Experiment (WOCE) data.

An analysis of ocean volume, heat and freshwater transports from a fully con-strained general circulation model is described. Output from a data synthesis, or state estimation, method is used by which the model was forced to a large-scale, time varying global ocean data set over six years. Time-mean fluxes estimated from this fully time-dependent circulation have converged with independent time-independent estimates from box inversions over most parts of the world ocean but especially in the southern hemisphere. However, heat transport estimates differ substantially in the North Atlantic where our estimates result in only 1/2 previous heat transports. The estimated mean circulation around Australia involves a net volume flux of 14 Sv through the Indonesian Through flow and the Mozambique Channel. In addition we show that this flow regime exist on all time scales above one month rendering the variability in the South Pacific strongly coupled to the Indian Ocean. Moreover, the dynamically consistent variations in the model show temporal variability of oceanic heat fluxes, heat storage and atmospheric exchanges that are complex and with a strong dependence upon location, depth, and time-scale. Results presented demonstrate the great potential of an ocean /state estimation system to provide a dynamical description of the time-dependent observed heat transport and heat content changes and their relation to air-sea interactions

F18-FDG PET/CT imaging early predicts pathologic complete response to induction chemoimmunotherapy of locally advanced head and neck cancer: preliminary single-center analysis of the checkrad-cd8 trial

Aim In the CheckRad-CD8 trial patients with locally advanced head and neck squamous cell cancer are treated with a single cycle of induction chemo-immunotherapy (ICIT). Patients with pathological complete response (pCR) in the re-biopsy enter radioimmunotherapy. Our goal was to study the value of F-18-FDG PET/CT in the prediction of pCR after induction therapy. Methods Patients treated within the CheckRad-CD8 trial that additionally received FDG- PET/CT imaging at the following two time points were included: 3–14 days before (pre-ICIT) and 21–28 days after (post-ICIT) receiving ICIT. Tracer uptake in primary tumors (PT) and suspicious cervical lymph nodes (LN +) was measured using different quantitative parameters on EANM Research Ltd (EARL) accredited PET reconstructions. In addition, mean FDG uptake levels in lymphatic and hematopoietic organs were examined. Percent decrease (Δ) in FDG uptake was calculated for all parameters. Biopsy of the PT post-ICIT acquired after FDG-PET/CT served as reference. The cohort was divided in patients with pCR and residual tumor (ReTu). Results Thirty-one patients were included. In ROC analysis, ΔSUVmax PT performed best (AUC = 0.89) in predicting pCR (n = 17), with a decline of at least 60% (sensitivity, 0.77; specificity, 0.93). Residual SUVmax PT post-ICIT performed best in predicting ReTu (n = 14), at a cutpoint of 6.0 (AUC = 0.91; sensitivity, 0.86; specificity, 0.88). Combining two quantitative parameters (ΔSUVmax ≥ 50% and SUVmax PT post-ICIT ≤ 6.0) conferred a sensitivity of 0.81 and a specificity of 0.93 for determining pCR. Background activity in lymphatic organs or uptake in suspected cervical lymph node metastases lacked significant predictive value. Conclusion FDG-PET/CT can identify patients with pCR after ICIT via residual FDG uptake levels in primary tumors and the related changes compared to baseline. FDG-uptake in LN + had no predictive value. Trial registry ClinicalTrials.gov identifier: NCT03426657

Circulation characteristics in three eddy-permitting models of the North Atlantic

A systematic intercomparison of three realistic eddy-permitting models of the North Atlantic circulation has been performed. The models use different concepts for the discretization of the vertical coordinate, namely geopotential levels, isopycnal layers, terrain-following (sigma) coordinates, respectively. Although these models were integrated under nearly identical conditions, the resulting large-scale model circulations show substantial differences. The results demonstrate that the large-scale thermohaline circulation is very sensitive to the model representation of certain localised processes, in particular to the amount and water mass properties of the overflow across the Greenland-Scotland region, to the amount of mixing within a few hundred kilometers south of the sills, and to several other processes at small or sub-grid scales. The different behaviour of the three models can to a large extent be explained as a consequence of the different model representation of these processes