69 research outputs found

    Las fuentes y el ambiente de un pasaje comprometido de Las postrimerías del hombre (1603), de fray Pedro de Oña

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    The reasons are studied why a work of Christian edification, written by a Catholic author (Las postrimerías del hombre), should appear in the 1747 Index of forbidden books. Its sources, Chasseneux and Lemonnier de Lesnauderie, were upholders of sixteenth-century Pietism and were sentenced to expurgation for their use of apocryphal auctoritates.Se estudian las razones por las que una obra de edificación cristiana de un autor católico (Las postrimerías del hombre) acaba apareciendo en el Índice de libros prohibidos de 1747: sus fuentes, Chasseneux y Lemonnier de Lesnauderie, en la línea más pietista del siglo XVI, fueron condenados a expurgo por recurrir a auctoritates apócrifas

    Dos palabras curiosas en un documento gallego del siglo XII

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    This paper studies the terms subricius and gallinarius, which are featured in a document given by Fernando II, King of León, in 1170. Additionally, the paper discusses the possibilities of computer programs managing textual corpora in lexicographical research. Keywords : Obliuionis incommoda ; subricius ; gallinarius ; maiorinus ; comes

    La Biblia, los Padres y la exégesis de lo ridículo

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    La expresión «meante a Ia pared» en Ia traducción bíblica de Casiodoro Reina da pie a una investigación acerca del sistema exegético de los Padres de Ia Iglesia y los comentaristas cuando se enfrentan a locuciones para ellos desconocidas o aparentemente ridículas.The expression «any that pisseth against the wall>> is the turning-point of a research upon the exegetical system of the Fathers and later Church writers who must face unknown idioms and apparently ridiculous sentences in the Bible

    El problema del acercamiento a los textos escritos en latín, y las tendencias de investigación en Filología latina medieval: una visión crítica de todo ello

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    Este trabajo se ocupa de exponer y, en todo caso, analizar, algunas de las más recientes tendencias de investigación en Filología latina medieval; también se tienen en cuenta los más útiles instrumenta laboris.This paper deals with some of the latest trends in medieval Latin Philology, and many of their more useful resources are analysed as wel

    Effects of intubation timing in patients with COVID-19 throughout the four waves of the pandemic : a matched analysis

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    The primary aim of our study was to investigate the association between intubation timing and hospital mortality in critically ill patients with COVID-19-associated respiratory failure. We also analysed both the impact of such timing throughout the first four pandemic waves and the influence of prior non-invasive respiratory support on outcomes. This is a secondary analysis of a multicentre, observational and prospective cohort study that included all consecutive patients undergoing invasive mechanical ventilation due to COVID-19 from across 58 Spanish intensive care units (ICU) participating in the CIBERESUCICOVID project. The study period was between 29 February 2020 and 31 August 2021. Early intubation was defined as that occurring within the first 24 h of intensive care unit (ICU) admission. Propensity score (PS) matching was used to achieve balance across baseline variables between the early intubation cohort and those patients who were intubated after the first 24 h of ICU admission. Differences in outcomes between early and delayed intubation were also assessed. We performed sensitivity analyses to consider a different timepoint (48 h from ICU admission) for early and delayed intubation. Of the 2725 patients who received invasive mechanical ventilation, a total of 614 matched patients were included in the analysis (307 for each group). In the unmatched population, there were no differences in mortality between the early and delayed groups. After PS matching, patients with delayed intubation presented higher hospital mortality (27.3% versus 37.1%, p =0.01), ICU mortality (25.7% versus 36.1%, p=0.007) and 90-day mortality (30.9% versus 40.2%, p=0.02) when compared to the early intubation group. Very similar findings were observed when we used a 48-hour timepoint for early or delayed intubation. The use of early intubation decreased after the first wave of the pandemic (72%, 49%, 46% and 45% in the first, second, third and fourth wave, respectively; first versus second, third and fourth waves p<0.001). In both the main and sensitivity analyses, hospital mortality was lower in patients receiving high-flow nasal cannula (n=294) who were intubated earlier. The subgroup of patients undergoing NIV (n=214) before intubation showed higher mortality when delayed intubation was set as that occurring after 48 h from ICU admission, but not when after 24 h. In patients with COVID-19 requiring invasive mechanical ventilation, delayed intubation was associated with a higher risk of hospital mortality. The use of early intubation significantly decreased throughout the course of the pandemic. Benefits of such an approach occurred more notably in patients who had received high-flow nasal cannul
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