77 research outputs found
Changes induced by glucose in the plasma membrane properties of pancreatic islets
Partially purified membranes obtained from rat pancreatic isolated islets preincubated for 3 min with 3.3 and 16.6 mM glucose were labelled with 1,6-diphenyl-1,3,5-hexatriene to study fluorescence polarization. Other islets, incubated for 5 min with the same glucose concentration, were extracted and phospholipids separated by thin-layer chromatography. The composition of phospholipids of fatty acids was then studied by gas-liquid chromatography. Arrhenius plots of the microviscosity in membranes obtained from islets exhibited two components, a steeper slope below 18 degrees C and a gentler slope above 18 degrees C, indicating greater flow activation energy at temperatures below the transition point. Exposure of islets to 16.6 mM glucose significantly increased the flow activation energy (delta E), below and above the transition point. Islets incubated for 5 min with 16.6 mM glucose showed an increase in the percentage composition of 12:0 and 18:2 together with a decrease in the 20:2 W6 and 22:3 W3 fatty acids esterified to phospholipids. Regardless of these changes, no significant alterations occurred in the proportion of saturated fatty acids or in the double bond index; these measurements therefore did not account for the effects of glucose concentration in flow activation energy. The thermotropic changes reported here might be the consequence of some degree of disorder induced by glucose upon the membrane structure. This order alteration could either favor the membrane fusion which occurs during the emiocytosis or only reflects the consequence of such a process
Approximating Fixation Probabilities in the Generalized Moran Process
We consider the Moran process, as generalized by Lieberman et al. (Nature 433:312–316, 2005). A population resides on the vertices of a finite, connected, undirected graph and, at each time step, an individual is chosen at random with probability proportional to its assigned “fitness” value. It reproduces, placing a copy of itself on a neighbouring vertex chosen uniformly at random, replacing the individual that was there. The initial population consists of a single mutant of fitness r>0 placed uniformly at random, with every other vertex occupied by an individual of fitness 1. The main quantities of interest are the probabilities that the descendants of the initial mutant come to occupy the whole graph (fixation) and that they die out (extinction); almost surely, these are the only possibilities. In general, exact computation of these quantities by standard Markov chain techniques requires solving a system of linear equations of size exponential in the order of the graph so is not feasible. We show that, with high probability, the number of steps needed to reach fixation or extinction is bounded by a polynomial in the number of vertices in the graph. This bound allows us to construct fully polynomial randomized approximation schemes (FPRAS) for the probability of fixation (when r≥1) and of extinction (for all r>0)
On Synchronization in a Lattice Model of Pulse-Coupled Oscillators
We analyze the collective behavior of a lattice model of pulse-coupled
oscillators. By means of computer simulations we find the relation between the
intrinsic dynamics of each member of the population and their mutual
interaction that ensures, in a general context, the existence of a fully
synchronized regime. This condition turns out to be the same than the obtained
for the globally coupled population. When the condition is not completely
satisfied we find different spatial structures. This also gives some hints
about self-organized criticality.Comment: 4 pages, RevTex, 1 PostScript available upon request, To appear in
Phys. Rev. Let
Damping mechanisms for oscillations in solar prominences
Small amplitude oscillations are a commonly observed feature in
prominences/filaments. These oscillations appear to be of local nature, are
associated to the fine structure of prominence plasmas, and simultaneous flows
and counterflows are also present. The existing observational evidence reveals
that small amplitude oscillations, after excited, are damped in short spatial
and temporal scales by some as yet not well determined physical mechanism(s).
Commonly, these oscillations have been interpreted in terms of linear
magnetohydrodynamic (MHD) waves, and this paper reviews the theoretical damping
mechanisms that have been recently put forward in order to explain the observed
attenuation scales. These mechanisms include thermal effects, through
non-adiabatic processes, mass flows, resonant damping in non-uniform media, and
partial ionization effects. The relevance of each mechanism is assessed by
comparing the spatial and time scales produced by each of them with those
obtained from observations. Also, the application of the latest theoretical
results to perform prominence seismology is discussed, aiming to determine
physical parameters in prominence plasmas that are difficult to measure by
direct means.Comment: 36 pages, 16 figures, Space Science Reviews (accepted
Visual Analysis of a Cold Rolling Process Using Data-Based Modeling
International Conference on Engineering Applications of Neural Networks (13th. 2012. Coventry Univ, Otaniemi, Finland
Neutrino Masses, Mixing and New Physics Effects
We introduce a parametrization of the effects of radiative corrections from
new physics on the charged lepton and neutrino mass matrices, studying how
several relevant quantities describing the pattern of neutrino masses and
mixing are affected by these corrections. We find that the ratio omega = sin
theta / tan theta_atm is remarkably stable, even when relatively large
corrections are added to the original mass matrices. It is also found that if
the lightest neutrino has a mass around 0.3 eV, the pattern of masses and
mixings is considerably more stable under perturbations than for a lighter or
heavier spectrum. We explore the consequences of perturbations on some flavor
relations given in the literature. In addition, for a quasi-degenerate neutrino
spectrum it is shown that: (i) starting from a bi-maximal mixing scenario, the
corrections to the mass matrices keep tan theta_atm very close to unity while
they can lower tan theta_sol to its measured value; (ii) beginning from a
scenario with a vanishing Dirac phase, corrections can induce a Dirac phase
large enough to yield CP violation observable in neutrino oscillations.Comment: 14 pages, 21 figures. Uses RevTeX4. Added several comments and
references. Final version to appear in PR
Approximating Fixation Probabilities in the Generalized Moran Process
We consider the Moran process, as generalized by Lieberman, Hauert and Nowak
(Nature, 433:312--316, 2005). A population resides on the vertices of a finite,
connected, undirected graph and, at each time step, an individual is chosen at
random with probability proportional to its assigned 'fitness' value. It
reproduces, placing a copy of itself on a neighbouring vertex chosen uniformly
at random, replacing the individual that was there. The initial population
consists of a single mutant of fitness placed uniformly at random, with
every other vertex occupied by an individual of fitness 1. The main quantities
of interest are the probabilities that the descendants of the initial mutant
come to occupy the whole graph (fixation) and that they die out (extinction);
almost surely, these are the only possibilities. In general, exact computation
of these quantities by standard Markov chain techniques requires solving a
system of linear equations of size exponential in the order of the graph so is
not feasible. We show that, with high probability, the number of steps needed
to reach fixation or extinction is bounded by a polynomial in the number of
vertices in the graph. This bound allows us to construct fully polynomial
randomized approximation schemes (FPRAS) for the probability of fixation (when
) and of extinction (for all ).Comment: updated to the final version, which appeared in Algorithmic
Test of Lorentz and CPT violation with Short Baseline Neutrino Oscillation Excesses
The sidereal time dependence of MiniBooNE electron neutrino and anti-electron
neutrino appearance data are analyzed to search for evidence of Lorentz and CPT
violation. An unbinned Kolmogorov-Smirnov test shows both the electron neutrino
and anti-electron neutrino appearance data are compatible with the null
sidereal variation hypothesis to more than 5%. Using an unbinned likelihood fit
with a Lorentz-violating oscillation model derived from the Standard Model
Extension (SME) to describe any excess events over background, we find that the
electron neutrino appearance data prefer a sidereal time-independent solution,
and the anti-electron neutrino appearance data slightly prefer a sidereal
time-dependent solution. Limits of order 10E-20 GeV are placed on combinations
of SME coefficients. These limits give the best limits on certain SME
coefficients for muon neutrino to electron neutrino and anti-muon neutrino to
anti-electron neutrino oscillations. The fit values and limits of combinations
of SME coefficients are provided.Comment: 14 pages, 3 figures, and 2 tables, submitted to Physics Letters
J-PLUS: The javalambre photometric local universe survey
ABSTRACT: TheJavalambrePhotometric Local UniverseSurvey (J-PLUS )isanongoing 12-band photometricopticalsurvey, observingthousands of squaredegrees of theNorthernHemispherefromthededicated JAST/T80 telescope at the Observatorio Astrofísico de Javalambre (OAJ). The T80Cam is a camera with a field of view of 2 deg2 mountedon a telescopewith a diameter of 83 cm, and isequippedwith a uniquesystem of filtersspanningtheentireopticalrange (3500–10 000 Å). Thisfiltersystemis a combination of broad-, medium-, and narrow-band filters, optimallydesigned to extracttherest-framespectralfeatures (the 3700–4000 Å Balmer break region, Hδ, Ca H+K, the G band, and the Mg b and Ca triplets) that are key to characterizingstellartypes and delivering a low-resolutionphotospectrumforeach pixel of theobservedsky. With a typicaldepth of AB ∼21.25 mag per band, thisfilter set thusallowsforanunbiased and accuratecharacterization of thestellarpopulation in our Galaxy, itprovidesanunprecedented 2D photospectralinformationforall resolved galaxies in the local Universe, as well as accuratephoto-z estimates (at the δ z/(1 + z)∼0.005–0.03 precisionlevel) formoderatelybright (up to r ∼ 20 mag) extragalacticsources. Whilesomenarrow-band filters are designedforthestudy of particular emissionfeatures ([O II]/λ3727, Hα/λ6563) up to z < 0.017, theyalsoprovidewell-definedwindowsfortheanalysis of otheremissionlines at higherredshifts. As a result, J-PLUS has thepotential to contribute to a widerange of fields in Astrophysics, both in thenearbyUniverse (MilkyWaystructure, globular clusters, 2D IFU-likestudies, stellarpopulations of nearby and moderate-redshiftgalaxies, clusters of galaxies) and at highredshifts (emission-line galaxies at z ≈ 0.77, 2.2, and 4.4, quasi-stellarobjects, etc.). Withthispaper, wereleasethefirst∼1000 deg2 of J-PLUS data, containingabout 4.3 millionstars and 3.0 milliongalaxies at r < 21mag. With a goal of 8500 deg2 forthe total J-PLUS footprint, thesenumbers are expected to rise to about 35 millionstars and 24 milliongalaxiesbytheend of thesurvey.Funding for the J-PLUS Project has been provided by the Governments of Spain and Aragón through the Fondo de Inversiones de Teruel, the Spanish Ministry of Economy and Competitiveness (MINECO; under grants AYA2017-86274-P, AYA2016-77846-P, AYA2016-77237-C3-1-P, AYA2015-66211-C2-1-P, AYA2015-66211-C2-2, AYA2012-30789, AGAUR grant SGR-661/2017, and ICTS-2009-14), and European FEDER funding (FCDD10-4E-867, FCDD13-4E-2685
Milagro limits and HAWC sensitivity for the rate-density of evaporating Primordial Black Holes
postprin
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