314 research outputs found

    The Roman Villa of El Saucedo, Talavera la Nueva, Toledo: Archaeometric Analysis of the Tessellae from the Mosaic Pavements of a Convivial Space

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    Presentamos un estudio arqueométrico de un conjunto de teselas procedentes de los mosaicos que solaron algunas de las salas del espacio convivial, en el que pudieron llegar a reunirse hasta un total de 27 comensales. Los datos aportados por la difracción de rayos X y el estudio con microscopio han permitido determinar la composición mineralógica de las teselas y plantear hipótesis sobre su identificación petrográfica; sugiriéndose el empleo de diferentes tipos de rocas (cuarzoarenitas, cuarcitas y mármoles calcáreos) que ofrecían una paleta de colores ampliaWe present an archaeometric study of a group of tessellae from the floor mosaics of the Villa de Saucedo’s convivial space (a room with place for 27 guests). Data provided by X-ray diffraction and microscopic examination revealed the mineralogical composition of the tessellae and therefore allowed some hypotheses regarding their petrographic identification. The data suggest the use of different kinds of rocks (quartzarenites, quartzites and calcareous marbles), which allowed for a broad color palett

    Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin

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    Objectives. To compare the effectiveness of postcesarean thromboprophylaxis with two different regimens of bemiparin. Material and Methods. The study included 646 women with cesarean delivery in our hospital within a 1-year period, randomly assigned to one of two groups for prophylaxis with 3500 IU bemiparin once daily for 5 days or 3500 IU bemiparin once daily for 10 days. Results. There was one case of pulmonary embolism (first day following cesarean). An additional risk factor was present in 98.52% of the women, most frequently emergency cesarean, anemia, or obesity. The only risk factors for thromboembolic disease significantly related to pulmonary thromboembolism were placental abruption and prematurity. There were no differences in thromboembolic events among the two thromboprophylaxis regimens. Conclusions. Cesarean-related thromboembolic events were reduced in our study population due to the thromboprophylactic measures taken. Thromboprophylaxis with 3500 IU bemiparin once daily for 5 days following cesarean was sufficient to avoid thromboembolic events

    Predictive Model for Preeclampsia Combining sFlt-1, PlGF, NT-proBNP, and Uric Acid as Biomarkers

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    Angiogenic factors; Preeclampsia; Uric acidFactores angiogénicos; Preeclampsia; Ácido úricoFactors angiogènics; Preeclàmpsia; Àcid úricN-terminal pro-brain natriuretic peptide (NT-proBNP) and uric acid are elevated in pregnancies with preeclampsia (PE). Short-term prediction of PE using angiogenic factors has many false-positive results. Our objective was to validate a machine-learning model (MLM) to predict PE in patients with clinical suspicion, and evaluate if the model performed better than the sFlt-1/PlGF ratio alone. A multicentric cohort study of pregnancies with suspected PE between 24+0 and 36+6 weeks was used. The MLM included six predictors: gestational age, chronic hypertension, sFlt-1, PlGF, NT-proBNP, and uric acid. A total of 936 serum samples from 597 women were included. The PPV of the MLM for PE following 6 weeks was 83.1% (95% CI 78.5-88.2) compared to 72.8% (95% CI 67.4-78.4) for the sFlt-1/PlGF ratio. The specificity of the model was better; 94.9% vs. 91%, respectively. The AUC was significantly improved compared to the ratio alone [0.941 (95% CI 0.926-0.956) vs. 0.901 (95% CI 0.880-0.921), p < 0.05]. For prediction of preterm PE within 1 week, the AUC of the MLM was 0.954 (95% CI 0.937-0.968); significantly greater than the ratio alone [0.914 (95% CI 0.890-0.934), p < 0.01]. To conclude, an MLM combining the sFlt-1/PlGF ratio, NT-proBNP, and uric acid performs better to predict preterm PE compared to the sFlt-1/PlGF ratio alone, potentially increasing clinical precision.This work was supported by public funds obtained in competitive calls with peer review (grant PI19/00702), Insituto de Salud Carlos III, Spanish Ministry of Health, by the Maternal and Child Health and Development Network (SAMID, RD16/0022/0015), Instituto de Salud Carlos III, Madrid, Spain, the Spanish Clinical Research and Clinical Trials Platform, SCReN (Spanish Clinical Research Network), funded by the ISCIII-General Subdirectorate for Evaluation and Promotion of Research, through project PT13/0002/0028, integrated in the 2013–2016 R + D + I State Plan and co-financed by and the European Regional Development Fund (FEDER); and by the Primary Care Interventions to Prevent Maternal and Child Chronic Diseases of Perinatal and Developmental Origin Network (RICORS, RD21/0012/0001), Instituto de Salud Carlos III, Madrid, Spain, funded by the Recovery, Transformation and Resilience Plan 2017–2020, ISCIII, and by the European Union-Next Generation EU. Dr Cruz-Lemini is supported by Juan Rodés contract JR19/00047, Instituto de Salud Carlos III-Spanish Ministry of Health. Funding sources were not involved in study design, collection, analysis, and interpretation of data

    Physical Education through a joint curriculum in secondary schools

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    Resumen basado en el de la publicaciónLa Educación Física ha de adoptar un papel principal en la sociedad del bienestar, del tiempo libre y del ocio. Teniendo en cuenta los resultados de diversos estudios a nivel europeo y norteamericano, en relación a la Educación Física recibida por parte de los escolares, se plantea un proyecto con el objetivo principal de diseñar un currículum común del área de Educación Física entre los distintos centros de la zona de Almería, teniendo en cuenta la variedad y novedad de los contenidos a plantear en clase, intentando alejarse de los que tradicionalmente han predominado en las sesiones de Educación Física. Se espera que un mayor y amplio número de experiencias, que parten de los intereses del alumnado, tenga unos efectos positivos en la actitud y motivación de los mismos, tanto en las clases como en un impacto positivo en la adhesión a la actividad física a lo largo de toda su vida.AndalucíaES

    The use of a web application – SciFinder to complement the Organic Chemistry teaching to the student of the Degree in Pharmacy

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    La necesidad de motivación del alumno, además de la adaptación de la actual enseñanza a los créditos ECTS, han sido los motores que nos han llevado a proponer el uso de una aplicación web denominada SciFinder en la enseñanza de la Química Orgánica. Se trata de una herramienta imprescindible en la investigación avanzada que se utiliza en cualquier laboratorio de síntesis química. La Universidad de Granada dispone de una suscripción que permite 6 usos simultáneos a la que el alumno puede acceder a través de un acceso directo a SciFinder on Web en el sólo es necesario registrarse como usuario. Permitir al alumno transportarse a un laboratorio virtual es una de las múltiples posibilidades que ofrece esta aplicación web ayudándoles a complementar los conocimientos científicos básicos que se han explicado en clase. Durante el desarrollo de los distintos temas que componen la asignatura se plantearán reacciones concretas que el alumno deberá ampliar con la información que esta aplicación les proporciona: reactivos empleados en dichas reacciones condiciones de reacción (estequiometría, tiempo, temperatura…) bibliografía actual. Al final del curso académico se evaluará esta nueva experiencia mediante encuestas de opinión del alumnado para determinar dos aspectos fundamentales de la misma, el aumento de interés por la asignatura durante el desarrollo del trabajo y la dificultad en la realización del mismo.The need to motivate the students, besides adapting the teaching to the ECTS credits, have been the driving force that leads us to propose the use of a web application called Sci Finder in the education of Organic Chemistry. It is an essential tool used in any advanced research laboratory of synthetic chemistry. The University of Granada provides a subscription with 6 simultaneous accesses. The students may accede directly to the SciFinder on Web being only necessary the registration as users. One of the many possibilities that offers this web application allows to the student be transported to a virtual laboratory and complement the basic scientific knowledge explained in class. During the development of the different topics, specific reactions will be presented to the student and they may increase the information by using this application: reagents of the reactions reaction conditions (stoichiometry, time, temperature…) up-to-date bibliography At the end of the academic year this new experience will be evaluate through opinion poll to the student in order to determinate two essential aspect, the interest increase for the subject during the development of this work and the difficulty in carrying out it

    Controlling Nerve Growth with an Electric Field Induced Indirectly in Transparent Conductive Substrate Materials

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    N.C.-P., A.M.R., and C.D.M. conceived and designed the study. N.-C.P., J.M.-V., and A.M.C. prepared the substrate materials and conducted electrochemical and AFM analysis. Z.Z. performed time lapse nerve growth experiments and analysis under the supervision of A.M.R. A.M.R. and N.C.-P. drafted the manuscript from an early draft prepared by Z.Z. All the authors participated in refining drafts. Equal contribution from the University of Aberdeen and Institut de Ciència de Materials de Barcelona-CSIC is acknowledged. This work was funded by the European Commission FP6 NEST Program (Contract 028473), MAT2011-24363 and MAT2015-65192-R from the Spanish Science Ministry, La Marato de TV3 Foundation (Identification Number 110131), and Severo Ochoa Programme for Centres of Excellence in R&D (SEV-2015-0496).Peer reviewedPostprin

    Is GNSS real-time positioning a reliable option to validate erosion studies at olive grove environments?

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    Aim of study: Soil degradation in agricultural areas is a widespread problem. In this framework, a data validation methodology is presented, including a study of the spatial resolution of Global Navigation Satellite System (GNSS) measurements, the calculation of erosion/deposition models, and the contribution of dual frequency and low-cost single frequency GNSS receivers.Area of study: A test olive grove in SE Spain.Material and methods: The study is based on three observation campaigns, between 2016 and 2018, using different GNSS receivers and working modes. The comparison between different surveys provide the volumetric variation over the analyzed period.Main results: Considering the dual-frequency receiver, there was no statistically significant difference between the means and the variances from 1.5 m and from 4.5 m data resolution at the 0.05 significance level. In order to estimate vertical differences from successive GNSS campaigns a differential digital elevation approach was applied. Although the differences depended on the zone of the test area and they changed along the monitoring period, the erosion rate could be catalogued as very low. The dual-frequency receiver satisfied the vertical centimetric precision limits for high accurate Digital Elevation Model (DEM), making it a reliable and accurate option to validate erosion studies in small areas.Research highlights: The results have allowed the characterization of multi-annual spatial redistribution of the topsoil at local scale, being of great help to design future prevention actions for the “tillage erosion” in olive grove environments. However, more tests are needed to guarantee the feasibility of low-cost receivers

    Desarrollo organizacional de las empresas mexicanas ante el covid-19: estrategias y acciones operativas

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    This work is characterized by determining the current Mexican companies conditions in face of the pandemic generated by COVID-19. The objective is to detect the strategies and operational actions that companies use to promote organizational development, based on the hypothesis that al least 80% of Mexican companies do so optimally. An exploratory study was developed, due to the fact that it’s a topic insufficiently studied, but at the same time novel and current issue. Likewise, descriptive, because it’s intended to specify the characteristics of Mexican companies in times of COVID-19. To obtain information and data analysis, the Survey about the Economic Impact Generated by COVID-19 in Companies (INEGI, 2020) was used, which aims to obtain information on the effects of the contingency caused by COVID-19 in Mexican companies. It was concluded that Mexican companies carry out pertinent health actions, however, they must promote operational strategies to face the pandemic, because there are 40% of companies that don’t implement any operational action.El presente trabajo, se caracteriza por determinar las condiciones actuales de las empresas mexicanas ante la pandemia generada por el COVID-19. El objetivo es detectar las estrategias y acciones operativas que emplean las empresas para impulsar el desarrollo organizacional, partiendo de la hipótesis, de que al menos el 80% de las empresas mexicanas, lo hace de forma óptima. Se desarrolló un estudio exploratorio, debido a que es un tema poco estudiado, pero a su vez novedoso y de actualidad; así mismo, descriptivo, porque se pretende especificar las características de las empresas mexicanas en tiempos del COVID-19. Para la obtención de información y análisis de datos, se empleó la Encuesta sobre el Impacto Económico Generado por COVID-19 en las Empresas (INEGI, 2020), que tiene como finalidad obtener información sobre las afectaciones de la contingencia originada por el COVID-19 en las empresas de México. Se concluyó que las empresas mexicanas, realizan acciones sanitarias pertinentes, sin embargo, deben impulsar estrategias operativas para hacer frente a la pandemia, ya que hay un 40% de empresas que no instrumentan alguna acción operativa
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