336 research outputs found

    The blood groups in Portuguese India

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    Sementes contra a varíola: Joaquim Vás e a tradução científica das pevides de bananeira brava em Goa, Índia (1894-1930) Seeds against smallpox: Joaquim Vás and the scientific translation of bananeira brava seeds in Goa, India (1894-1930)

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    Em 1914, em Goa, antiga colĂŽnia portuguesa na Índia, o mĂ©dico AntĂłnio Joaquim VĂĄs anunciou a descoberta de um fabuloso tratamento contra a varĂ­ola: a aplicação clĂ­nica das pevides, ou sementes, de bananeira brava, medicamento de origem vegetal extraĂ­do das prĂĄticas mĂ©dicas indianas. Este artigo investiga as circunstĂąncias do sucesso e insucesso dessa descoberta. A constituição das pevides de bananeira brava como medicamento contra a varĂ­ola, no inĂ­cio do sĂ©culo XX, Ă© interpretada com base no conceito de tradução cientĂ­fica. Argumenta-se que a tradução das pevides - de atividade indĂ­gena a terapĂȘutica cientĂ­fica - constitui um caso de criação de quasi-medicamentos, uma tradução mĂ©dia. Embora habitando um lugar problemĂĄtico no programa de tradução cientĂ­fica, as pevides circularam ativamente no interior da prĂłpria ciĂȘncia, persistindo contra a varĂ­ola nas prĂĄticas mĂ©dicas.<br>In 1914, in the former Portuguese colony of Goa, India, the physician AntĂłnio Joaquim VĂĄs announced the discovery of a wonderful treatment for smallpox, entailing clinical application of seeds from the bananeira brava (Heliconia biahi Sw.m.), a plant remedy allegedly derived from Indian medical practices. The present article explores the circumstances surrounding the successes and failures of this discovery. The concept of scientific translation is used to interpret the transformation of bananeira bravaseeds into an early twentieth-century remedy for smallpox. This transfer from indigenous use to scientific therapeutics constitutes the creation of a quasi-medicine, that is, a case of 'medium translation'. Although these seeds occupy a problematic place within the program of scientific translation, they enjoyed active circulation within science and remained a part of medical practices for combating smallpox

    Multiplicity dependence of light (anti-)nuclei production in p–Pb collisions at sNN=5.02 TeV

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    The measurement of the deuteron and anti-deuteron production in the rapidity range −1 < y < 0 as a function of transverse momentum and event multiplicity in p–Pb collisions at √sNN = 5.02 TeV is presented. (Anti-)deuterons are identified via their specific energy loss dE/dx and via their time-of- flight. Their production in p–Pb collisions is compared to pp and Pb–Pb collisions and is discussed within the context of thermal and coalescence models. The ratio of integrated yields of deuterons to protons (d/p) shows a significant increase as a function of the charged-particle multiplicity of the event starting from values similar to those observed in pp collisions at low multiplicities and approaching those observed in Pb–Pb collisions at high multiplicities. The mean transverse particle momenta are extracted from the deuteron spectra and the values are similar to those obtained for p and particles. Thus, deuteron spectra do not follow mass ordering. This behaviour is in contrast to the trend observed for non-composite particles in p–Pb collisions. In addition, the production of the rare 3He and 3He nuclei has been studied. The spectrum corresponding to all non-single diffractive p-Pb collisions is obtained in the rapidity window −1 < y < 0 and the pT-integrated yield dN/dy is extracted. It is found that the yields of protons, deuterons, and 3He, normalised by the spin degeneracy factor, follow an exponential decrease with mass number

    Charged-particle multiplicity distributions over a wide pseudorapidity range in proton-proton collisions at √s = 0.9, 7, and 8 TeV

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    We present the charged-particle multiplicity distributions over a wide pseudorapidity range (−3.4<η<5.0) for pp collisions at s√=0.9,7, and 8 TeV at the LHC. Results are based on information from the Silicon Pixel Detector and the Forward Multiplicity Detector of ALICE, extending the pseudorapidity coverage of the earlier publications and the high-multiplicity reach. The measurements are compared to results from the CMS experiment and to PYTHIA, PHOJET and EPOS LHC event generators, as well as IP-Glasma calculations

    Production of ÎŁ(1385)± and Ξ(1530)0 in p–Pb collisions at √sNN = 5.02 TeV

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    The transverse momentum distributions of the strange and double-strange hyperon resonances (ÎŁ(1385)±, Ξ(1530)0) produced in p-Pb collisions at sNN−−−√=5.02 TeV were measured in the rapidity range −0.5<yCMS<0 for event classes corresponding to different charged-particle multiplicity densities, ⟹dNch/dηlab⟩. The mean transverse momentum values are presented as a function of ⟹dNch/dηlab⟩, as well as a function of the particle masses and compared with previous results on hyperon production. The integrated yield ratios of excited to ground-state hyperons are constant as a function of ⟹dNch/dηlab⟩. The equivalent ratios to pions exhibit an increase with ⟹dNch/dηlab⟩, depending on their strangeness content

    Multiharmonic Correlations of Different Flow Amplitudes in Pb-Pb Collisions at sNN=2.76\sqrt{s_{_{NN}}}=2.76 TeV

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    The event-by-event correlations between three flow amplitudes are measured for the first time in Pb-Pb collisions, using higher-order symmetric cumulants. We find that different three-harmonic correlations develop during the collective evolution of the medium when compared to correlations that exist in the initial state. These new results cannot be interpreted in terms of previous lower-order flow measurements since contributions from two-harmonic correlations are explicitly removed in the new observables. A comparison to Monte Carlo simulations provides new and independent constraints for the initial conditions and system properties of nuclear matter created in heavy-ion collisions

    Neutral pion and η meson production at mid-rapidity in Pb–Pb collisions at √sNN = 2.76 TeV

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    Neutral pion and η meson production in the transverse momentum range 1 < pT < 20 GeV/c have been measured at mid-rapidity by the ALICE experiment at the Large Hadron Collider (LHC) in central and semi-central Pb-Pb collisions at sNN−−−−√ = 2.76 TeV. These results were obtained using the photon conversion method as well as the PHOS and EMCal detectors. The results extend the upper pT reach of the previous ALICE π0 measurements from 12 GeV/c to 20 GeV/c and present the first measurement of η meson production in heavy-ion collisions at the LHC. The η/π0 ratio is similar for the two centralities and reaches at high pT a plateau value of 0.457 ± 0.013stat ± 0.018syst. A suppression of similar magnitude for π0 and η meson production is observed in Pb-Pb collisions with respect to their production in pp collisions scaled by the number of binary nucleon-nucleon collisions. We discuss the results in terms of NLO pQCD predictions and hydrodynamic models. The measurements show a stronger suppression with respect to what was observed at lower center-of-mass energies in the pT range 6 < pT < 10 GeV/c. At pT < 3 GeV/c, hadronization models describe the π0 results while for the η some tension is observed
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