1,183 research outputs found
Light, medium-weight or heavy? The nature of the first supermassive black hole seeds
Observations of hyper-luminous quasars at reveal the rapid growth of
supermassive black holes (SMBHs ) whose origin is still
difficult to explain. Their progenitors may have formed as remnants of massive,
metal free stars (light seeds), via stellar collisions (medium-weight seeds)
and/or massive gas clouds direct collapse (heavy seeds). In this work we
investigate for the first time the relative role of these three seed
populations in the formation of SMBHs within an Eddington-limited gas
accretion scenario. To this aim, we implement in our semi-analytical
data-constrained model a statistical description of the spatial fluctuations of
Lyman-Werner (LW) photo-dissociating radiation and of metal/dust enrichment.
This allows us to set the physical conditions for BH seeds formation, exploring
their relative birth rate in a highly biased region of the Universe at .
We find that the inclusion of medium-weight seeds does not qualitatively change
the growth history of the first SMBHs: although less massive seeds () form at a higher rate, the mass growth of a
SMBH at is driven by efficient gas accretion (at a sub-Eddington rate)
onto its heavy progenitors (). This conclusion holds
independently of the critical level of LW radiation and even when medium-weight
seeds are allowed to form in higher metallicity galaxies, via the so-called
super-competitive accretion scenario. Our study suggests that the genealogy of
SMBHs is characterized by a rich variety of BH progenitors, which
represent only a small fraction () of all the BHs that seed
galaxies at .Comment: (21 pages, 18 figures, 2 tables. Accepted for publication in MNRAS
Lensed CMB power spectra from all-sky correlation functions
Weak lensing of the CMB changes the unlensed temperature anisotropy and
polarization power spectra. Accounting for the lensing effect will be crucial
to obtain accurate parameter constraints from sensitive CMB observations.
Methods for computing the lensed power spectra using a low-order perturbative
expansion are not good enough for percent-level accuracy. Non-perturbative
flat-sky methods are more accurate, but curvature effects change the spectra at
the 0.3-1% level. We describe a new, accurate and fast, full-sky
correlation-function method for computing the lensing effect on CMB power
spectra to better than 0.1% at l<2500 (within the approximation that the
lensing potential is linear and Gaussian). We also discuss the effect of
non-linear evolution of the gravitational potential on the lensed power
spectra. Our fast numerical code is publicly available.Comment: 16 pages, 4 figures. Changes to match PRD version including new
section on non-linear corrections. CAMB code available at http://camb.info
Rhythmic dynamics and synchronization via dimensionality reduction : application to human gait
Reliable characterization of locomotor dynamics of human walking is vital to understanding the neuromuscular control of human locomotion and disease diagnosis. However, the inherent oscillation and ubiquity of noise in such non-strictly periodic signals pose great challenges to current methodologies. To this end, we exploit the state-of-the-art technology in pattern recognition and, specifically, dimensionality reduction techniques, and propose to reconstruct and characterize the dynamics accurately on the cycle scale of the signal. This is achieved by deriving a low-dimensional representation of the cycles through global optimization, which effectively preserves the topology of the cycles that are embedded in a high-dimensional Euclidian space. Our approach demonstrates a clear advantage in capturing the intrinsic dynamics and probing the subtle synchronization patterns from uni/bivariate oscillatory signals over traditional methods. Application to human gait data for healthy subjects and diabetics reveals a significant difference in the dynamics of ankle movements and ankle-knee coordination, but not in knee movements. These results indicate that the impaired sensory feedback from the feet due to diabetes does not influence the knee movement in general, and that normal human walking is not critically dependent on the feedback from the peripheral nervous system
Coupling of alpha(1)-Adrenoceptors to ERK1/2 in the Human Prostate
Introduction: alpha(1)-Adrenoceptors are considered critical for the regulation of prostatic smooth muscle tone. However, previous studies suggested further alpha(1)-adrenoceptor functions besides contraction. Here, we investigated whether alpha(1)-adrenoceptors in the human prostate may activate extracellular signal-regulated kinases (ERK1/2). Methods: Prostate tissues from patients undergoing radical prostatectomy were stimulated in vitro. Activation of ERK1/2 was assessed by Western blot analysis. Expression of ERK1/2 was studied by immunohistochemistry. The effect of ERK1/2 inhibition by U0126 on phenylephrine-induced contraction was studied in organ-bath experiments. Results: Stimulation of human prostate tissue with noradrenaline (30 mu M) or phenylephrine (10 mu M) resulted in ERK activation. This was reflected by increased levels of phosphorylated ERK1/2. Expression of ERK1/2 in the prostate was observed in smooth muscle cells. Incubation of prostate tissue with U0126 (30 mu M) resulted in ERK1/2 inhibition. Dose-dependent phenylephrine-induced contraction of prostate tissue was not modulated by U0126. Conclusions: alpha(1)-Adrenoceptors in the human prostate are coupled to ERK1/2. This may partially explain previous observations suggesting a role of alpha(1)-adrenoceptors in the regulation of prostate growth. Copyright (C) 2011 S. Karger AG, Base
The OPERA experiment Target Tracker
The main task of the Target Tracker detector of the long baseline neutrino
oscillation OPERA experiment is to locate in which of the target elementary
constituents, the lead/emulsion bricks, the neutrino interactions have occurred
and also to give calorimetric information about each event. The technology used
consists in walls of two planes of plastic scintillator strips, one per
transverse direction. Wavelength shifting fibres collect the light signal
emitted by the scintillator strips and guide it to both ends where it is read
by multi-anode photomultiplier tubes. All the elements used in the construction
of this detector and its main characteristics are described.Comment: 25 pages, submitted to Nuclear Instrument and Method
Emulsion sheet doublets as interface trackers for the OPERA experiment
New methods for efficient and unambiguous interconnection between electronic
counters and target units based on nuclear photographic emulsion films have
been developed. The application to the OPERA experiment, that aims at detecting
oscillations between mu neutrino and tau neutrino in the CNGS neutrino beam, is
reported in this paper. In order to reduce background due to latent tracks
collected before installation in the detector, on-site large-scale treatments
of the emulsions ("refreshing") have been applied. Changeable Sheet (CSd)
packages, each made of a doublet of emulsion films, have been designed,
assembled and coupled to the OPERA target units ("ECC bricks"). A device has
been built to print X-ray spots for accurate interconnection both within the
CSd and between the CSd and the related ECC brick. Sample emulsion films have
been extensively scanned with state-of-the-art automated optical microscopes.
Efficient track-matching and powerful background rejection have been achieved
in tests with electronically tagged penetrating muons. Further improvement of
in-doublet film alignment was obtained by matching the pattern of low-energy
electron tracks. The commissioning of the overall OPERA alignment procedure is
in progress.Comment: 19 pages, 19 figure
Measurement of the rate of nu_e + d --> p + p + e^- interactions produced by 8B solar neutrinos at the Sudbury Neutrino Observatory
Solar neutrinos from the decay of B have been detected at the Sudbury
Neutrino Observatory (SNO) via the charged current (CC) reaction on deuterium
and by the elastic scattering (ES) of electrons. The CC reaction is sensitive
exclusively to nu_e's, while the ES reaction also has a small sensitivity to
nu_mu's and nu_tau's. The flux of nu_e's from ^8B decay measured by the CC
reaction rate is
\phi^CC(nu_e) = 1.75 +/- 0.07 (stat)+0.12/-0.11 (sys.) +/- 0.05(theor) x 10^6
/cm^2 s.
Assuming no flavor transformation, the flux inferred from the ES reaction
rate is
\phi^ES(nu_x) = 2.39+/-0.34 (stat.)+0.16}/-0.14 (sys) x 10^6 /cm^2 s.
Comparison of \phi^CC(nu_e) to the Super-Kamiokande Collaboration's precision
value of \phi^ES(\nu_x) yields a 3.3 sigma difference, providing evidence that
there is a non-electron flavor active neutrino component in the solar flux. The
total flux of active ^8B neutrinos is thus determined to be 5.44 +/-0.99 x
10^6/cm^2 s, in close agreement with the predictions of solar models.Comment: 6 pages (LaTex), 3 figures, submitted to Phys. Rev. Letter
Measurement of the atmospheric muon charge ratio with the OPERA detector
The OPERA detector at the Gran Sasso underground laboratory (LNGS) was used
to measure the atmospheric muon charge ratio in the TeV energy region. We
analyzed 403069 atmospheric muons corresponding to 113.4 days of livetime
during the 2008 CNGS run. We computed separately the muon charge ratio for
single and for multiple muon events in order to select different energy regions
of the primary cosmic ray spectrum and to test the charge ratio dependence on
the primary composition. The measured charge ratio values were corrected taking
into account the charge-misidentification errors. Data have also been grouped
in five bins of the "vertical surface energy". A fit to a simplified model of
muon production in the atmosphere allowed the determination of the pion and
kaon charge ratios weighted by the cosmic ray energy spectrum.Comment: 14 pages, 10 figure
Planck Intermediate Results. IV. The XMM-Newton validation programme for new Planck galaxy clusters
We present the final results from the XMM-Newton validation follow-up of new
Planck galaxy cluster candidates. We observed 15 new candidates, detected with
signal-to-noise ratios between 4.0 and 6.1 in the 15.5-month nominal Planck
survey. The candidates were selected using ancillary data flags derived from
the ROSAT All Sky Survey (RASS) and Digitized Sky Survey all-sky maps, with the
aim of pushing into the low SZ flux, high-z regime and testing RASS flags as
indicators of candidate reliability. 14 new clusters were detected by XMM,
including 2 double systems. Redshifts lie in the range 0.2 to 0.9, with 6
clusters at z>0.5. Estimated M500 range from 2.5 10^14 to 8 10^14 Msun. We
discuss our results in the context of the full XMM validation programme, in
which 51 new clusters have been detected. This includes 4 double and 2 triple
systems, some of which are chance projections on the sky of clusters at
different z. We find that association with a RASS-BSC source is a robust
indicator of the reliability of a candidate, whereas association with a FSC
source does not guarantee that the SZ candidate is a bona fide cluster.
Nevertheless, most Planck clusters appear in RASS maps, with a significance
greater than 2 sigma being a good indication that the candidate is a real
cluster. The full sample gives a Planck sensitivity threshold of Y500 ~ 4 10^-4
arcmin^2, with indication for Malmquist bias in the YX-Y500 relation below this
level. The corresponding mass threshold depends on z. Systems with M500 > 5
10^14 Msun at z > 0.5 are easily detectable with Planck. The newly-detected
clusters follow the YX-Y500 relation derived from X-ray selected samples.
Compared to X-ray selected clusters, the new SZ clusters have a lower X-ray
luminosity on average for their mass. There is no indication of departure from
standard self-similar evolution in the X-ray versus SZ scaling properties.
(abridged)Comment: accepted by A&
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