Noncommutative Super Yang-Mills Theories with 8 Supercharges and Brane Configurations

In this paper we consider D=4 NCSYM theories with 8 supercharges. We study these theories through a proper type IIA (and M-theory) brane configuration. We find the one loop beta function of these theories and show that there is an elliptic curve describing the moduli space of the theory, which is in principle the same as the curve for the commutative counter-part of our theory. We study some other details of the dynamics by means of this brane configuration.Comment: 14 pages, no figures, v2: typos correcte

On Measuring Split-SUSY Neutralino and Chargino Masses at the LHC

In Split-Supersymmetry models, where the only non-Standard Model states produceable at LHC-energies consist of a gluino plus neutralinos and charginos, it is conventionally accepted that only mass differences among these latter are measureable at the LHC. The present work shows that application of a simple `Kinematic Selection' technique allows full reconstruction of neutralino and chargino masses from one event, in principle. A Monte Carlo simulation demonstrates the feasibilty of using this technique at the LHC.Comment: 17 pages, 4 figures; EPJC versio

Noncommutative SO(n) and Sp(n) Gauge Theories

We study the generalization of noncommutative gauge theories to the case of orthogonal and symplectic groups. We find out that this is possible, since we are allowed to define orthogonal and symplectic subgroups of noncommutative unitary gauge transformations even though the gauge potentials and gauge transformations are not valued in the orthogonal and symplectic subalgebras of the Lie algebra of antihermitean matrices. Our construction relies on an antiautomorphism of the basic noncommutative algebra of functions which generalizes the charge conjugation operator of ordinary field theory. We show that the corresponding noncommutative picture from low energy string theory is obtained via orientifold projection in the presence of a non-trivial NSNS B-field.Comment: 17 pages; considerations about fermions added and some minor change

Final State Interactions in Hypernuclear Decay

We present an update of the One-Meson-Exchange (OME) results for the weak decay of s- and p-shell hypernuclei (Ref. Phys. Rev. C {\bf 56}, 339 (1997)), paying special attention to the role played by final state interactions between the emitted nucleons. The present study also corrects for a mistake in the inclusion of the $K$ and $K^*$ exchange mechanisms, which substantially increases the ratio of neutron-induced to proton-induced transitions, $\Gamma_n/\Gamma_p$. With the most up-to-date model ingredients, we find that the OME approach is able to describe very satisfactorily most of the measured observables, including the ratio $\Gamma_n/\Gamma_p$.Comment: 20 pages, 2 eps figure

Dirac Quantization of Open Strings and Noncommutativity in Branes

We apply the Dirac bracket quantization to open strings attached to branes in the presence of background antisymmetric field and recover an inherent noncommutativity in the internal coordinates of the brane.Comment: 25 pp, typos corrected, minor change

Weak Field Black Hole Formation in Asymptotically AdS Spacetimes

We use the AdS/CFT correspondence to study the thermalization of a strongly coupled conformal field theory that is forced out of its vacuum by a source that couples to a marginal operator. The source is taken to be of small amplitude and finite duration, but is otherwise an arbitrary function of time. When the field theory lives on $R^{d-1,1}$, the source sets up a translationally invariant wave in the dual gravitational description. This wave propagates radially inwards in $AdS_{d+1}$ space and collapses to form a black brane. Outside its horizon the bulk spacetime for this collapse process may systematically be constructed in an expansion in the amplitude of the source function, and takes the Vaidya form at leading order in the source amplitude. This solution is dual to a remarkably rapid and intriguingly scale dependent thermalization process in the field theory. When the field theory lives on a sphere the resultant wave either slowly scatters into a thermal gas (dual to a glueball type phase in the boundary theory) or rapidly collapses into a black hole (dual to a plasma type phase in the field theory) depending on the time scale and amplitude of the source function. The transition between these two behaviors is sharp and can be tuned to the Choptuik scaling solution in $R^{d,1}$.Comment: 50 pages + appendices, 6 figures, v2: Minor revisions, references adde

Emergence of Anti-Cancer Drug Resistance: Exploring the Importance of the Microenvironmental Niche via a Spatial Model

Practically, all chemotherapeutic agents lead to drug resistance. Clinically, it is a challenge to determine whether resistance arises prior to, or as a result of, cancer therapy. Further, a number of different intracellular and microenvironmental factors have been correlated with the emergence of drug resistance. With the goal of better understanding drug resistance and its connection with the tumor microenvironment, we have developed a hybrid discrete-continuous mathematical model. In this model, cancer cells described through a particle-spring approach respond to dynamically changing oxygen and DNA damaging drug concentrations described through partial differential equations. We thoroughly explored the behavior of our self-calibrated model under the following common conditions: a fixed layout of the vasculature, an identical initial configuration of cancer cells, the same mechanism of drug action, and one mechanism of cellular response to the drug. We considered one set of simulations in which drug resistance existed prior to the start of treatment, and another set in which drug resistance is acquired in response to treatment. This allows us to compare how both kinds of resistance influence the spatial and temporal dynamics of the developing tumor, and its clonal diversity. We show that both pre-existing and acquired resistance can give rise to three biologically distinct parameter regimes: successful tumor eradication, reduced effectiveness of drug during the course of treatment (resistance), and complete treatment failure

Plasma matrix metalloproteinases in neonates having surgery for congenital heart disease

During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfunction. This study was to determine plasma matrix-metalloproteinases in neonates after cardiopulmonary-bypass and their relation to post-operative course. A prospective observational study included 18 neonates having cardiac surgery. Plasma matrix-metalloproteinases-2 and 9 activities were measured by gelatin-zymography pre-operatively, on starting cardiopulmonarybypass, 7–8 min after aortic cross-clamp release, and 1h, 4h, 24h, and 3d after cardiopulmonary-bypass. Plasma concentrations of their tissue inhibitors 1 and 2 were determined by enzyme-linked immunosorbent assay. Cardiac function was assessed by serial echocardiography. Paired t-tests and Wilcoxon tests were used to assess temporal changes, and linear correlation with simultaneous clinical and cardiac function parameters were assessed using Pearson's product-moment correlation coefficient. Plasma matrix-metalloproteinases activities and their tissue inhibitor concentrations decreased during cardiopulmonary-bypass. Matrix-metalloproteinase-2 plasma activity increased progressively starting 1h after cardiopulmonarybypass and returned to pre-operative levels at 24h. Matrix-metalloproteinase-9 plasma activity increased significantly after release of aortic cross-clamp, peaked 7–8min later, and returned to baseline at 24h. Plasma tissueinhibitor 1 and 2 concentrations increased 1h after cardiopulmonary-bypass. Cardiac function improved from 4h to 3d after surgery (p<0.05). There was no evidence of significant correlations between matrix-metalloproteinases or their inhibitors and cardiac function, inotrope scores, organ dysfunction scores, ventilation days, or hospital days. The temporal profile of plasma matrix-metalloproteinases and their inhibitors after cardiopulmonary-bypass in neonates are similar to adults. In neonates, further study should determine whether circulating matrix-metalloproteinases are useful biomarkers of disease activity locally within the myocardium, and hence of clinical outcomes

Teleparallel Gravity and Dimensional Reductions of Noncommutative Gauge Theory

We study dimensional reductions of noncommutative electrodynamics on flat space which lead to gauge theories of gravitation. For a general class of such reductions, we show that the noncommutative gauge fields naturally yield a Weitzenbock geometry on spacetime and that the induced diffeomorphism invariant field theory can be made equivalent to a teleparallel formulation of gravity which macroscopically describes general relativity. The Planck length is determined in this setting by the Yang-Mills coupling constant and the noncommutativity scale. The effective field theory can also contain higher-curvature and non-local terms which are characteristic of string theory. Some applications to D-brane dynamics and generalizations to include the coupling of ordinary Yang-Mills theory to gravity are also described.Comment: 31 pages LaTeX; References adde

Search for a strongly decaying neutral charmed pentaquark

We present a search for a charmed pentaquark decaying strongly to $D^{(*)-}p$. Finding no evidence for such a state, we set limits on the cross section times branching ratio relative to $D^{*-}$ and $D^-$ under particular assumptions about the production mechanism.Comment: To be published in Physics Letters